• Journal of the Korea Convergence Society
• /
• v.10 no.2
• /
• pp.309-313
• /
• 2019

This study examined the response of the EMG of URA, LRA, IO, EO and RFM of various types of abdominal motion (crunch, spine V-up on ball, prone V-up on slide board, prone V-up on TRX, and prone V-up power wheel). The subjects performed anisometric contact of abs during these exercises. Tests have shown that there were no statistically significant differences between EO, URA and LRA between any movements. However, during the inspection of IO, the positive-wawed V-up motion showed significantly greater muscle activity than during the slide movement. Also, EMG activity during crunch was significantly lower than any other five exercises. These results indicate that in the implementation of equilateral absolutism, the equipment-free based exercise gives an impetus similar to equipment-based exercise. Abdominal muscle tissue is considered one of the five components that make up an individual's core. The abdominal muscles also ensure proper functioning of the lumbar spine. Although all abdominal muscles contribute to lumbar stabilization, TA & IO has been shown to perform major stabilizers.

• The Journal of the Institute of Internet, Broadcasting and Communication
• /
• v.22 no.6
• /
• pp.31-36
• /
• 2022

In this paper, we present the design, manufacture and test results of Backend unit for SAR(Synthetic Aperture Radar) that can be applied on a small satellite. The Backend unit for SAR was designed with a control/storage board, TRX(transmission and receiving) board and a power supply board as a single unit in consideration of the applying of a small satellite. The control/storage board uses RFSoC to generate wideband chirp signal, generate operating timings, and perform control and calculations for SAR operation. The TRX board is designed to convert the wideband chirp signal generated by the control/storage board to the operating frequency of X-band by up-converting the frequency. Since small size, light weight, and low cost are important consideration for small satellite, MIL/Industrial grade components were appropriately applied and the at the same time it was designed to ensure mission life through the radiation test, analysis and space environment tests.

• Journal of Plant Biotechnology
• /
• v.33 no.1
• /
• pp.1-9
• /
• 2006

Peroxiredoxins (Prxs) are ubiquitously distributed and play important functions in diverse cellular signaling systems. The proteins are largely classified into three groups, such as typical 2-Cys Prx, atypical 2-Cys Prx, and 1-Cys Prx, that are distinguished by their catalytic mechanisms and number of Cys residues. From the three classes of Prxs, the typical 2-Cys Prx containing the two-conserved Cys residues at its N-terminus and C-terminus catalyzes $H_2O_2$ with the use of thioredoxin (Trx) as an electron donor. During the catalytic cycle, the N-terminal Cys residue undergoes a peroxide-dependent oxidation to sulfenic acid, which can be further oxidized to sulfinic acid at the presence of high concentrations of $H_2O_2$ and a Trx system containing Trx, Trx reductase, and NADPH. The sulfinic acid form of 2-Cys Prx is reduced by the action of sulfiredoxin which requires ATP as an energy source. Under the strong oxidative or heat shock stress conditions, 2-Cys Prx in eukaryotes rapidly switches its protein structure from low-molecular-weight species to high-molecular-weight protein structures. In accordance with its structural changes, the protein concomitantly triggers functional switching from a peroxidase to a molecular chaperone, which can protect its substrate denaturation from external stress. In addition to its N-terminal active site, the C-terminal domain including 'YF-motif' of 2-Cys Prx plays a critical role in the structural changes. Therefore, the C-terminal truncated 2-Cys Prxs are not able to regulate their protein structures and highly resistant to $H_2O_2$-dependent hyperoxidation, suggesting that the reaction is guided by the peroxidatic Cys residue. Based on the results, it may be concluded that the peroxidatic Cys of 2-Cys Prx acts as an '$H_2O_2$-sensor' in the cells. The oxidative stress-dependent regulation of 2-Cys Prx provides a means of defense systems in cells to adapt stress conditions by activating intracellular defense signaling pathways. Particularly, 2-Cys Prxs in plants are localized in chloroplasts with a dynamic protein structure. The protein undergoes conformational changes again oxidative stress. Depending on a redox-potential of the chloroplasts, the plant 2-Cys Prx forms super-molecular weight protein structures, which attach to the thylakoid membranes in a reversible manner.

• Journal of Life Science
• /
• v.24 no.7
• /
• pp.713-720
• /
• 2014

In this study, the antioxidative and anti-inflammatory activities of Ardisia arborescens ethanol extract (AAEE) were evaluated using in vitro assays and a cell culture model system. AAEE exhibited potent scavenging activity against 1,1-diphenyl-2-picryl hydrazyl (DPPH), similar to ascorbic acid, which was used as a positive control. Moreover, AAEE effectively suppressed lipopolysaccharide (LPS)- and hydrogen peroxide ($H_2O_2$)-induced reactive oxygen species (ROS) in RAW 264.7 cells. Furthermore, AAEE induced the expression of antioxidative enzymes, heme oxygenase 1 (HO-1), and thioredoxin reductase 1 (TrxR1), in addition to their upstream transcription factor, nuclear factor-E2-related factor 2 (Nrf2), in a dose-dependent manner. The upstream signaling pathways of mitogen-activated protein kinases (MAPKs) might regulate the modulation of HO-1, TrxR1, and Nrf2 expression. On the other hand, AAEE inhibited LPS-induced nitric oxide (NO) formation, without cytotoxicity. Suppression of NO formation was the result of AEEE-induced down-regulation of inducible NO synthase (iNOS). The suppression of NO and iNOS by AAEE might be modulated by their upstream transcription factor, nuclear factor (NF)-${\kappa}B$, and activator protein (AP)-1 pathways. Taken together, these results provide important new insights into the antioxidative and anti-inflammatory activities of A. arborescens. AAAEE might represent a promising material in the field of nutraceuticals.

• 한국생물공학회:학술대회논문집
• /
• 2005.10a
• /
• pp.620-620
• /
• 2005

• Proceedings of the PSK Conference
• /
• 2005.11a
• /
• pp.123-124
• /
• 2005

• Progress in Medical Physics
• /
• v.5 no.2
• /
• pp.27-34
• /
• 1994

In this study, we developed E.C.G telemetry system by using a digital communication method. This system is composed of a number of Ambulatory Telemetry System(ATS)'s that use for the same frequency and one center monitoring system(CMS) utilized the personal computer. The purpose of the ATS is, Therefore, to present for acqusition ECG data and transmitting to CMS. The ATS hardware is based on one chip microprocessor (8096) included A/D convert, ECG pre amplifier, ID-decoder, TRX Gateway and FM TRX module. Using the PC can be convinet to processing and deposite for long terms continued patient data.

• BMB Reports
• /
• v.32 no.5
• /
• pp.497-501
• /
• 1999

Biotinylation of recombinant proteins is a powerful tool for the detection and analysis of proteins of interest in a large variety of assay systems. The recent development of in vivo biotinylation techniques in E. coli has opened new possibilities for the production of site-specifically biotinylated proteins without the need for further manipulation after the isolation of the recombinantly expressed proteins. In the present study, a novel vector set was generated which allows the convenient cloning and expression of proteins of interest fused with an N-terminal in vivo biotinylated thioredoxin (TRX) protein. These vectors were derived from the previously reported pBIOTRX vector into which was incorporated part of the pBluescript II+phagemid multiple cloning site (MCS), amplified by PCR using a pair of sophisticated oligonucleotide primers. The functionality of these novel vectors was examined in this system by recombinant expression of rat transforming growth factor-$\beta$. Western-blot analysis using TRX-specific antibodies or peroxidase-conjugated streptavidin confirmed the successful induction of the fusion protein and the in vivo conjugation of biotin molecules, respectively. The convenience of molecular subcloning provided by the MCS and the effective in vivo biotinylation of proteins of interest makes this novel vector set an interesting alternative for the production of biotinylated proteins.

• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.25 no.6A
• /
• pp.893-899
• /
• 2000

WDM technology has been an emerging issue for the efficient use of optical links. WDM uses a number of different wavelengths that are assigned to each channel. The minimal number of optical transcievers and receivers should be used in a node to build an economic WDM transmission system without degrading system performance. Hence, the analysis of performance parameters such as throughput and delay is important to guarantee the WDM system performance. In this paper, the performance of a MAC protocol on a slotted WDM system that has a tunable transmitter(TTX), a tunable receiver(TRX), and a fixed receiver(FRX), respectively, on each node, was statistically analyzed. The computer simulation validates the performance analysis.

• Tuberculosis and Respiratory Diseases
• /
• v.59 no.2
• /
• pp.142-150
• /
• 2005

Background : Continuous growth stimulation by various factors, as well as chronic oxidative stress, may co-exist in many solid tumors, such as lung cancer. A new family of antioxidant proteins, the peroxiredoxins (Prxs), have been implicated in the regulation of many cellular processes, including cell proliferation, differentiation and apoptosis. However, a real pathophysiological significance of Prx proteins, especially in lung disease, has not been sufficiently defined. Therefore, this study was conducted to investigate the distribution and expression of various Prx isoforms in lung cancer and other pulmonary conditions. Method : Patients diagnosed with lung cancer, and who underwent surgery at the Ajou Medical Center, were enrolled. The expressions of Prxs, Thioredoxin (Trx) and Thioredoxin reductase (TR) were analyzed using proteomic techniques and the subcellular localization of Prx proteins was studied using immunohistochemistry on normal mouse lung tissue. Result : Immunohistochemical staining has shown the isoforms of Prx I, II, III and V are predominantly expressed in bronchial and alveolar lining epithelia, as well as in the alveolar macrophages of the normal mouse lung. The isoforms of Prx I and III, and thioredoxin were also found to be over-expressed in the lung cancer tissues compared to their paired normal lung controls. There was also an increased amount of the oxidized form of Prx I, as well as a putative truncated form of Prx III, in the lung cancer samples when analyzed using 2-dimensional electrophoresis. In addition, a 43 kDa intermediate molecular weight protein band, and other high molecular weight bands of over 20 kDa, recognized by the anti-Prx I antibody, were present in the tissue extracts of lung cancer patients on 1-Dimensional electrophoresis, which require further investigation. Conclusion : The over-expressions of Prx I and III, and Trx in human lung cancer tissue, as well as their possible chaperoning function, may represent an attempt by tumor cells to adjust to their microenvironment in a manner advantageous to their survival and proliferation, while maintaining their malignant potential.