• Journal of Home Health Care Nursing
• /
• v.26 no.1
• /
• pp.51-63
• /
• 2019

Purpose: The objective of this study was to investigate mothers' perception of antibiotic use for their children. Methods: A cross-sectional survey was conducted of a convenient sample of 210 mothers who visited the two pediatric hospitals in D city. Descriptive statistics, t-test, analysis of variance, Kruskal-Wallis test, Mann-Whitney U test, and Pearson correlation coefficients with SPSS WIN 24.0 were used to analyze the data. Results: The perception of mothers on antibiotic use for their children was relatively low (3.28/5) and showed a statistically significant difference based on the mothers' educational background (${\chi}^2=15.30$, p<.001). About 57-77% of participants discontinued or reduced the dosage of the antibiotics if their children's symptoms were relieved, and about 60% of them perceived that antibiotics treat viral infections. Mothers' adherence to specific doses of antibiotics in their children was positively correlated with their knowledge and beliefs (r=.17, p=.014) and their attitude regarding the use of antibiotics (r=.17, p=.014). Only 1.4% of the participants had educational experience regarding the correct use of antibiotics. Conclusion: Based on the results, it can be concluded that an educational program for mothers should be developed and to verify its effects in order to induce proper use of antibiotics among mothers.

• Korean journal of applied entomology
• /
• v.26 no.2 s.71
• /
• pp.89-97
• /
• 1987

Antagonistic microorganisms from rhizosphere soil were isolated, identified, and applied successfully as the biocontrol agents of damping-off caused by Rhizoctonia spp. Rhizosphere antagonists isolated from rhizosphere soil were identified as Trichoderma viride, T. harzianum, T. hamatum, T. polysporum, Gliocladium sp., Pseudomonas fluorescence, P. stutzeri, P. cepacia, Enterobacter sp., Serratia sp. and Erwinia herbicola. Of these, the most promising ones in vitro were T. virdie, T. harzianum, Gliocladium sp., Serratia sp., P. stutzeri, and P. cepacia. These above six antagonists were efficient in reducing disease incidence to $40{\sim}70%$ when the reselected rhizosphere antagonists preparations were applied to the soil at $10^6$ propagules per gram. Among six antagonists, T. viride was the most promising biocontrol agents against R. solani isolates in soil. The suppressive effect was more evident in steam-sterilized soil than in non-sterilized field soil.

• Proceedings of the Korean Society of Toxicology Conference
• /
• 2001.05a
• /
• pp.160-160
• /
• 2001

We recently reported that, 2-chloro-3-(4-hexylphenyI)-amino-l, 4-naphthoquinone(NQ304), a naphthoquinone derivative, had potent inhibitory effects on the platelet aggregation in vitro and thrombosis in vivo. Furthermore, we reported the antiplatelet mechanism of NQ304 by the reduction of the thromboxane A2 formation, inhibition of adenosine triphosphate release and intracellular calcium mobilization.(omitted)

• Journal of Korean Society of Forest Science
• /
• v.10 no.1
• /
• pp.5-6
• /
• 1970

Abies koreansa Wilson grows at the upper part of Mts. Halla, Chiri, Mudung, Kaji and Dokyu. It was at first collected by Father U. Faurie on the May of 1907 from the Mt. Halla, Quelpaert. Cone colour of this species varies from green to black purple and the typical colour of it is violet purple. A form of black purple was named by Hatushima in 1934. Green and reddish brown or reddish purple colours of this species were discovered recently at the Mt. Halla. All these forms can be identified as the following. for. koreana - Abies koreana Wilson in Journ. Arn. Arb. 1, 188(1920) ; Mori, En. 27(1922) ; Uyeki, Timb. Tr. 117(1926) et Woody Pl. 5(1940) ; Chung et al, Comm. Nam. 12(1937) ; Handb. Kor. Manch. For. 71(1939) ; Kawamoto, III. For. P1. 16(1940) ; T. Lee, Arb. Kor. 12(1947) et Billiogr. Woody P1. 233(1966) ; Nakai, Synopt. 23(1952)-A. nephrolepis sensu Nakai, Rep. Veg. Chirisan 23, no. 27(1915) et Rep. Veg. Quelpaert Isl. 13, no. 142 (1915), non Max. (1866) Strobili violaceo-purpurei, bracteis viridibus juvenilibus vel stramineis matureis. Mt. Halla ( Lee, no. 970527K. ) for. chlorocarpa, forma nova ; Strobili et bracteae viridi sed rubescent in apice juvenili inflerescentiae. Mt. Halla ( Lee, no. 970527C. ) for. rubrocarpa, forma nova ; Strobili et bracteae rubro-purpurei vel rubro-fusui Mt. Halla ( Lee, no. 970527R. ) for nigrocarpa Hatushima, Rep. Exp. For. Kyushu U. 40(1934) ; T. Lee, Arb. Kor. 12(1947) et Bibliogr. Woody P1,233(1966). Strobili et bracteae nigro-purpurei. Mt. Halla (Lee, no. 970527N. )

• Journal of Animal Science and Technology
• /
• v.45 no.5
• /
• pp.857-864
• /
• 2003

In a trial involving 120 pigs, the effects of transport time on blood profile and meat quality in pigs were investigated. One group of 60 animals was subjected to 20 min and the others to 2 h transport time, and held in lairage for 1 h 30 min. There was not significantly different in the carcass weight, backfat thickness and carcass grade between groups. Cortisol and lactic dehydrogenase(LDH) concentrations were significantly(P〈0.05) higher in the group transported for 2 h compared with the group transported for 20 min. There was not significantly different(P〉0.05) in meat quality(pH$_1$, pH$_{u}$, drip loss, cooking loss, hardness, CIE L$^{*}$, a$^{*}$, b$^{*}$ and NPPC) and skin damage of pork carcass between groups. These results imply that the stress could be affected by transport time in transit without meat quality.

• Koreanishche Zeitschrift fur Deutsche Sprachwissenschaft
• /
• v.2
• /
• pp.75-100
• /
• 2000

Das Ziel dieses Aufsatzes ist es, dass wir aile seit Lakoff(1965) als inchoative Verben angenommenen Konstruktionen aus Adjektiv + werden bzw. die dazu synonymen Verben nicht mehr unter eine Kategorie 'Inchoativ' subsumieren, und diese Konstruktionen mutatives(werden + dick), ingressives(werden + krank) und duratives Verb(werden + dicker) untergliedern, und $schlie{\ss}lich$ auf Grund dieser Analyse Vendlers 4 Situationstypen Zustand, Prozess, Accomplishmen und Achievement noch deutlicher spezifizieren. Mutative Verben sind rechtsbegrenzte Prozessverben, ingressive Verben linksbegrenzte Zustandsverben, und durative Verben nichtbegrenzte Prozessverben. In mutativen und durativen Verben wird der Vorgang als Kontinuum aufgefasst, und in ingressiven Verben wird der Vorgang als diskontinuierliche Aufeinanderfolge zweler $Zust\"{a}nde.\;\"{U}brigens$ haben mutative Verben obligatolisch Prozesscharakter und der Prozess bewirkt $Zustandsver\"{a}nderung$. Ingressive Verben haben nicht $prim\"{a}r$ Prozesscharakter, und $m\"{o}glicher$ Prozess $verl\"{a}uft$ innerhalb emes Zustandes. Es gibt also $gen\"{u}gend$ Motivation $daf\"{u}r$, werden bei allen drei Klassen in einheitlicher Weise zu beschreiben. Nach $g\"{a}ngiger$ Auffassung ist die Semantische Form(SF) von werden vom semantisch unmarkierten sein durch das telische $Pt\"{a}dikat\;_{BECOME}$ unterschieden. In diesem Aufsatz $ersetzt_{CHANGE}\;das\;Pradikat\;_{BECOME;}$ die Bedeutung von $von\;_{BECOME}$ ist eine der $m\"{o}glichen kontextabh\"{a}ngigen$ semantischen Anreicherungen $von\;_{CHANGE.\;CHANGE}$ ist unterbestimmt $bez\"{u}glich\;Telizit\"{a}t$ und Prozesshaftigkeit. $_{CHANGE}[P(X)]$ ist die Basis­bedeutungskomponente von werden in allen adjektivischen werden­Konstruktionen. Mit Hilfe von $Pr\"{a}dikaten\;_{CHANGE,\;TARG},\;und\;_{ATOM}$ bekommen wir die Beschreibung von $Markiertheitsverh\"{a}Itnissen$ zwischen den Situations­typen, die mit nur zwei semantischen Klassifizierungskomponenten(${\pm}Prozess,\;{\pm}Become$) nicht darzustellen sind. Veranderungssituationen sind $Nicht-Zust\"{a}nde$, markiert durch das $Pt\"{a}dikat\;_{CHANGE}.\;Ver\"{a}nderungs­situationen$ mit einem Ziel(TARG) sind Ereignisse. Eine Veranderung ohne Begrenzung ist ein Prozess. Achievements sind $atomare(_{ATOM})\;Ereignisse(_{TARG})$. Accomplishments sind durch TARG hinreichend charakterisiert, d.h. eine $zielbezogene(_{TARG})$ Veranderung, die nicht als $atomar(_{-ATOM})$ gekennzeichnet ist, ist ein Accomplishment.

• 한국초전도학회:학술대회논문집
• /
• v.12
• /
• pp.25-25
• /
• 2002

• Asian Pacific Journal of Cancer Prevention
• /
• v.15 no.10
• /
• pp.4331-4338
• /
• 2014

$N^1$-(2, 5-dimethoxyphenyl)-$N^8$-hydroxyoctanediamide (N25) is a novel SAHA cap derivative of HDACi, with a patent (No. CN 103159646). This invention is a hydroxamic acid compound with a structural formula of $RNHCO(CH_2)6CONHOH$ (wherein R=2, 5dimethoxyaniline), a pharmaceutically acceptable salt which is soluble. In the present study, we investigated the effects of N25 with regard to drug distribution and molecular docking, and anti-proliferation, apoptosis, cell cycling, and $LD_{50}$. First, we designed a molecular approach for modeling selected SAHA derivatives based on available structural information regarding human HDAC8 in complex with SAHA (PDB code 1T69). N25 was found to be stabilized by direct interaction with the HDAC8. Anti-proliferative activity was observed in human glioma U251, U87, T98G cells and human lung cancer H460, A549, H1299 cells at moderate concentrations ($0.5-30{\mu}M$). Compared with SAHA, N25 displayed an increased antitumor activity in U251 and H460 cells. We further analyzed cell death mechanisms activated by N25 in U251 and H460 cells. N25 significantly increased acetylation of Histone 3 and inhibited HDAC4. On RT-PCR analysis, N25 increased the mRNA levels of p21, however, decreased the levels of p53. These resulted in promotion of apoptosis, inducing G0/G1 arrest in U251 cells and G2/M arrest in H460 cells in a time-dependent and dose-dependent manner. In addition, N25 was able to distribute to brain tissue through the blood-brain barrier of mice ($LD_{50}$: 240.840mg/kg). In conclusion, our findings demonstrate that N25 will provide an invaluable tool to investigate the molecular mechanism with potential chemotherapeutic value in several malignancies, especially human glioma.

• Journal of Animal Environmental Science
• /
• v.18 no.1
• /
• pp.9-18
• /
• 2012

The output of Korea's livestock industry represents about 40% of the total agricultural production, making it the most high value-added sector in the entire agricultural and forestry industry. However, the fatal epidemics such as foot-and-mouth disease and avian influenza spurs demands for the advanced management of livestock production with IT technologies. U-Livestock means the application of ubiquitous technologies to livestock production. In this study, U-Livestock service models are established on the basis of the life cycle of livestock by using local and overseas cases. The objectives, contents, and structures of service models are required to be designed in detail respectively. The integration of such service models is expected to he1p modernize the livestock industry and raise the productivity of sector.

• Korean Journal of Environmental Biology
• /
• v.27 no.2
• /
• pp.183-190
• /
• 2009

Characterization of the analysis of forest vegetation, soil environmental conditions and water quality were performed from March 2003 to March 2007. The two basins were characterized by cultivated area (Kaesim reservoir) and mountain area (Jangchan reservoir), and divided into eleven small basins, where dynamics of pollutants, forest vegetation and soil environmental conditions were surveyed. The vegetation can be divided into 10 types by $Z\ddot{u}rich$-Montpellier school's method. Pearson coefficients between vegetation type and water quality were correlated with dissolved oxygen (DO) in the Quercus variabilis community at the 5% level and total phosphorus (TP) in the Larix leptolepis plantation at the 1% level. Especially total phosphorous and total nitrogen increased in small basins where the proportion of cultivated and residential area increased. The analysis of influences of pollutant discharge on water quality showed that pollutant charge was very low in forest land area ($Y_{T-P}$=-0.0017X+0.2215, r=0.16, $Y_{COD}$=- 0.0395X+8.5051 r=0.47). The soil types of western area were comparatively simple, but those of eastern area were complicated with regosols, red-yellow soils, lithosoles, etc. The pH, total solid (TS) and volatile substance (VS) of the forest and agricultural land soils collected in each site were 5.4~6.9, 75.8~80.2%, and 3.80%~5.80%, respectively. According to the analytical result of soil environmental conditions, heavy metal contents fell short to the mean value of natural conditions. Runoff amount (Y) and depth of topsoil (X) were negatively correlated, $Y_{ron}=-1.0088X_{top}+35.378$ (r=0.68). The correlation was much lower in up-stream but much higher in down-stream, because permeation into soil particle was larger on down-stream due to its more or less gentle slope. Pearson coefficients between soil pH and water pH were statistically significant at 1% level.