• 대한수학회논문집
• /
• 제33권4호
• /
• pp.1141-1158
• /
• 2018

Hahn difference operator $D_{q,{\omega}}$ which is defined by $$D_{q,{\omega}}g(t)=\{{\frac{g(gt+{\omega})-g(t)}{t(g-1)+{\omega}}},{\hfill{20}}\text{if }t{\neq}{\theta}:={\frac{\omega}{1-q}},\\g^{\prime}({\theta}),{\hfill{83}}\text{if }t={\theta}$$ received a lot of interest from many researchers due to its applications in constructing families of orthogonal polynomials and in some approximation problems. In this paper, we investigate sufficient conditions for stability of the abstract linear Hahn difference equations of the form $$D_{q,{\omega}}x(t)=A(t)x(t)+f(t),\;t{\in}I$$, and $$D^2{q,{\omega}}x(t)+A(t)D_{q,{\omega}}x(t)+R(t)x(t)=f(t),\;t{\in}I$$, where $A,R:I{\rightarrow}{\mathbb{X}}$, and $f:I{\rightarrow}{\mathbb{X}}$. Here ${\mathbb{X}}$ is a Banach algebra with a unit element e and I is an interval of ${\mathbb{R}}$ containing ${\theta}$.

• 대한수학회보
• /
• 제59권4호
• /
• pp.929-949
• /
• 2022

Given an ACM set 𝕏 of points in a multiprojective space ℙ^m×ℙⁿ over a field of characteristic zero, we are interested in studying the Kähler different and the Cayley-Bacharach property for 𝕏. In ℙ¹×ℙ¹, the Cayley-Bacharach property agrees with the complete intersection property and it is characterized by using the Kähler different. However, this result fails to hold in ℙ^m×ℙⁿ for n > 1 or m > 1. In this paper we start an investigation of the Kähler different and its Hilbert function and then prove that 𝕏 is a complete intersection of type (d₁, …, d_m, d'₁, …, d'_n) if and only if it has the Cayley-Bacharach property and the Kähler different is non-zero at a certain degree. We characterize the Cayley-Bacharach property of 𝕏 under certain assumptions.

• Korean Journal of Acupuncture
• /
• 제21권3호
• /
• pp.137-146
• /
• 2004

Objective : The purpose of this study is to report the patient with peripheral neuropathy, who improved by Oriental medical treatment. Methods : The patient was managed by acupuncture, moxibustion, physical treatment and herbal medicine. We checked digital infrared thermographic imaging(D.I.T.I.), electromyography(E.M.G.), nerve conduction velocity(N.C.V.), deep tendon reflex(D.T.R.), sensory recover area and range of motion(R.O.M.) of knee & ankle. Results : After 6 week treatment, clinical sign(the movement and sense of leg) of improvement was appeared. Also E.M.G., N.C.V., D.T.R. and D.I.T.I. was recovered to nearly normal range. Conclusion : The results suggest that combination of acupunture, moxibustion and herbal medicine is good method for treatment of peripheral neuropathy. But further studies may be required to concretely prove the effectiveness of this methods for treating peripheral neuropathy.

• Kyungpook Mathematical Journal
• /
• 제49권3호
• /
• pp.473-481
• /
• 2009

In this paper, we study the uniqueness of entire functions and prove the following theorem. Let n(${\geq}$ 5), k be positive integers, and let $S_1$ = {z : $z^n$ = 1}, $S_2$ = {$a_1$, $a_2$, ${\cdots}$, $a_m$}, where $a_1$, $a_2$, ${\cdots}$, $a_m$ are distinct nonzero constants. If two non-constant entire functions f and g satisfy $E_f(S_1,2)$ = $E_g(S_1,2)$ and $E_{f^{(k)}}(S_2,{\infty})$ = $E_{g^{(k)}}(S_2,{\infty})$, then one of the following cases must occur: (1) f = tg, {$a_1$, $a_2$, ${\cdots}$, $a_m$} = t{$a_1$, $a_2$, ${\cdots}$, $a_m$}, where t is a constant satisfying $t^n$ = 1; (2) f(z) = $de^{cz}$, g(z) = $\frac{t}{d}e^{-cz}$, {$a_1$, $a_2$, ${\cdots}$, $a_m$} = $(-1)^kc^{2k}t\{\frac{1}{a_1},{\cdots},\frac{1}{a_m}\}$, where t, c, d are nonzero constants and $t^n$ = 1. The results in this paper improve the result given by Fang (M.L. Fang, Entire functions and their derivatives share two finite sets, Bull. Malaysian Math. Sc. Soc. 24(2001), 7-16).

• 대한기계학회:학술대회논문집
• /
• 대한기계학회 2005년도 창립60주년 기념 추계 학술대회
• /
• pp.209.2-209.2
• /
• 2005

• Asian-Australasian Journal of Animal Sciences
• /
• 제26권3호
• /
• pp.343-348
• /
• 2013

This experiment was conducted to evaluate the development of T cells in intrauterine growth retarded (IUGR) piglets at different gestational stages, and tentatively explore the relationship between T cells development and the Notch signaling pathway. A total of 18 crossbred (Landrace${\times}$Large white) primiparous sows were mated at similar weights and estruses and euthanized at d 60, 90 and 110 of gestation with six replicates for each time point. One IUGR and one normal fetus were picked from each litter. The T-cell subsets, mRNA expression of Delta-like1, Delta-like4, Jagged1, and Notch2 genes in the thymus were investigated. Compared to normal piglets, $CD3^+CD4^-CD8^+$ cells in IUGR fetuses at d 90 was 0.13% lower (p<0.05). At d 110 of gestation $CD8^+$ T cells in IUGR fetuses was 0.19% lower (p<0.05). The percentage of $CD8^+$ T cells was 3.14% lower (p<0.05) of the total T cells in IUGR pigs at d 60. The abundance of Notch2 and Delta-like4 mRNA at d 110 was 20.93% higher and 0.77% (p<0.05) lower, and Delta-like1 mRNA at d 90 was 0.19% (p<0.05) higher compared to normal pigs. These results suggested that normal fetuses had a greater proportion of T-cell subsets at earlier gestation periods, and the Notch signaling pathway was likely partially responsible for these differences to some degree.

• Clinical and Experimental Pediatrics
• /
• 제48권4호
• /
• pp.387-394
• /
• 2005

목 적 : 선천성 갑상선기능저하증에 대한 신생아 선별검사결과의 이상빈도는 실제 임상적으로 진단되는 질환의 발생빈도보다 훨씬 높다. 본원에서 시행되는 선천성 갑상선기능저하증에 대한 신생아 선별검사의 위양성률과 소환율을 알아보고 재태기간과 출생체중에 따른 검사결과치를 비교하여 각각의 결과에 따라 cut-off value를 재평가함으로써 임상에서 신생아 선별검사의 결과를 해석하고 질환을 진단하는데 도움을 주고자 하였다. 방 법 : 2000년 5월부터 2003년 1월까지 단국대학교병원에서 출생한 2,133명의 신생아를 대상으로 정상분만의 경우 생후 3일째, 제왕절개인 경우 생후 5일째, 신생아중환자실에 입원한 미숙아인 경우 생후 $14.3{\pm}12.4$일(5-79일) 이내에 신생아의 발뒤꿈치를 천자하여 모세혈을 검사용 채혈지에 묻혀 갑상선자극호르몬과 유리 $T_4$를 효소면역법으로 분석하였고 각각의 기존참고치인 $20{\mu}IU/mL$ 이상, 1 ng/dL 미만일 경우 소아과 외래로 불러 재검하였으며 이때 이학적 검사 및 주산기적 병력, 약물력, 모체질환 등의 여부를 조사하였고 혈청을 이용해 면역형광법에 의한 갑상선기능검사를 시행하였다. 결 과 : 1) 다른 질병이 없었던 1,749명의 갑상선자극호르몬과 유리 $T_4$의 평균${\pm}$표준편차는 각각 $9.01{\pm}5.82{\mu}IU/mL$, $1.99{\pm}0.90ng/dL$이었고 성별, 분만형태, 아프가 점수에 따른 차이는 없었다. 2) 재태연령과 출생체중에 따라 갑상선자극호르몬의 수치는 의미있는 차이가 없었고 유리 $T_4$의 수치는 의미있는 차이가 있었다(P<0.01). 3) 다른 질병이 있었던 384명의 갑상선자극호르몬과 유리 $T_4$의 평균${\pm}$표준편차는 각각 $9.17{\pm}7.22{\mu}IU/mL$, $1.52{\pm}0.75ng/dL$이었고, 건강한 신생아와 비교시 갑상선자극호르몬의 수치는 의미있는 차이가 없었고 유리 $T_4$의 수치는 의미있는 차이가 있었다(P<0.01). 4) 신생아 선별검사에서 131명이 소환되었고 재소환율은 7.48%이었으며, 이중 추적관찰이 가능했던 87명의 갑상선기능이 정상화된 기간은 출생체중과 의미있는 관계는 없었고, 출생주수와는 음의 상관관계를 보였다(P=0.042, Pearson 상관계수 -0.177). 5) 신생아 선별검사에서 재소환되어 선천성 갑상선기능저하증을 진단받은 환아는 모두 4명으로 2명은 갑상선자극호르몬 수치만 $20{\mu}IU/mL$ 이상이었고 2명은 유리 $T_4$ 수치만 1 ng/dL 미만이었으며, 3명은 건강한 신생아에, 1명은 질병이 있었던 군에 속했다. 6) Cut-off value를 본 연구에서 시행되었던 기준인 갑상선 자극호르몬이 $20{\mu}IU/mL$ 이상이거나 또는 유리 $T_4\;1\;ng/dL$ 미만인 경우 소환율, 양성예측률, 민감도, 특이도는 각각 7.48%, 2.29%, 75%, 92.6%이었다. 갑상선자극호르몬이 $20{\mu}IU/mL$ 이상이거나 유리 $T_4\;0.64\;ng/dL$ 미만인 경우에 소환율, 양성예측률, 민감도, 특이도가 각각 4.8%, 3.57%, 75%, 95.3%이었다. 결 론 : 결론적으로 선천성 갑상선기능저하증에 대한 신생아 선별검사에서 갑상선자극호르몬 및 유리 $T_4$ 모두를 선별검사로 사용하는 것은 타당하고, 현재의 cut-off value가 소환율이 높기는 하나 검사의 민감도를 고려할 때 cut-off를 바꾸기에는 문제가 있을 것으로 생각되며 향후 더 큰 대상군을 바탕으로 한 재평가가 필요하리라 생각된다.

• 전자통신동향분석
• /
• 제30권4호
• /
• pp.92-101
• /
• 2015

미래 전장은 정보 지식 기반의 첨단 전력체계를 확충하기 위해 향후 전력구조를 통합, 지휘통제통신(C4I) 체계와 생존성과 통합성이 향상된 전장의 네트워크중심전(NCW) 수행능력을 향상시킬 것이다. 사이버물리시스템(Cyber-Physical Systems: CPS)은 함정전투체계에 적용되고 있는 DDS를 포함하여 국방 M&S의 근간인 Live, Virture, Constructive(L-V-C) 체계의 큰 축을 형성하고 있다. 사물인터넷(Internet of Things: IoT) 기술은 센서네트워크, 통신, Radio Frequency Identification(RFID), Ubiquitous Sensor Network(USN), Machine to Machine(M2M), D2D 기술 및 상황인지, 지능서비스를 위한 정보수집/가공/융합/분석/예측기술을 포괄적으로 포함한 기술로서 미래산업을 이끌어 갈 차세대 선도 기술이며, 특히 군사적으로도 감시정찰 센서네트워크(USN), 견마형로봇, 경전투로봇과 무인기 기술 및 전술정보통신망체계(TICN) 등 첨단 통신네트워크 기술의 전력화 추세는 IoT 기술의 적용영역을 넓혀주고 있다. 감시정찰체계(Sensor)에서는 감시정찰 분야 영상정보 처리, 표적탐지 등과 관련된 IoT 기술 소요와 지휘통제통신(C4I) 체계의 상호운용성, 데이터링크, 지능형 통신체계 등 C4I 관련 IoT 기술 소요 및 타격체계(Shooter)의 내장형 SW 등 유 무인 무기체계 관련 IoT 기술의 소요가 증대될 것으로 예상된다. 본고는 CPS 및 IoT 기술의 군사적 활용방안 및 획득전략에 대한 적용기술 및 발전방향을 살펴본다.

• Nutrition Research and Practice
• /
• 제18권1호
• /
• pp.1-18
• /
• 2024

BACKGROUND/OBJECTIVES: Endoplasmic reticulum (ER) stress in adipose tissue causes an inflammatory response and leads to metabolic diseases. However, the association between vitamin D and adipose ER stress remains poorly understood. In this study, we investigated whether 1,25-dihydroxyvitamin D₃ (1,25(OH)₂D₃) alleviates ER stress in adipocytes. MATERIALS/METHODS: 3T3-L1 cells were treated with different concentrations (i.e., 10-100 nM) of 1,25(OH)₂D₃ after or during differentiation (i.e., on day 0-7, 3-7, or 7). They were then incubated with thapsigargin (TG, 500 nM) for an additional 24 h to induce ER stress. Next, we measured the mRNA and protein levels of genes involved in unfold protein response (UPR) and adipogenesis using real-time polymerase chain reaction and western blotting and quantified the secreted protein levels of pro-inflammatory cytokines. Finally, the mRNA levels of UPR pathway genes were measured in adipocytes transfected with siRNA-targeting Vdr. RESULTS: Treatment with 1,25(OH)₂D₃ during various stages of adipocyte differentiation significantly inhibited ER stress induced by TG. In fully differentiated 3T3-L1 adipocytes, 1,25(OH)₂D₃ treatment suppressed mRNA levels of Ddit3, sXbp1, and Atf4 and decreased the secretion of monocyte chemoattractant protein-1, interleukin-6, and tumor necrosis factor-α. However, downregulation of the mRNA levels of Ddit3, sXbp1, and Atf4 following 1,25(OH)₂D₃ administration was not observed in Vdr-knockdown adipocytes. In addition, exposure of 3T3-L1 preadipocytes to 1,25(OH)₂D₃ inhibited transcription of Ddit3, sXbp1, Atf4, Bip, and Atf6 and reduced the p-alpha subunit of translation initiation factor 2 (eIF2α)/eIF2α and p-protein kinase RNA-like ER kinase (PERK)/PERK protein ratios. Furthermore, 1,25(OH)₂D₃ treatment before adipocyte differentiation reduced adipogenesis and the mRNA levels of adipogenic genes. CONCLUSIONS: Our data suggest that 1,25(OH)₂D₃ prevents TG-induced ER stress and inflammatory responses in mature adipocytes by downregulating UPR signaling via binding with Vdr. In addition, the inhibition of adipogenesis by vitamin D may contribute to the reduction of ER stress in adipocytes.

• 물과 미래
• /
• 제6권2호
• /
• pp.30-37
• /
• 1973

The coefficient of the current meter generally determined by the maker Its coefficient is subject to being changed with time. Therefore the coefficient of the current meter has to be checked up before it is ready to be used Such an inspection is termed a current meter rating The current meter equipped an electronic apparatus and all the others are to be rated in a rating flume. The price current meter which is most widely used for measuring flow velocities ranging between 0.3m/sec and 3.5m/sec has been used in this study. The length of the flume and the optimum range of the rating in the cross section are determined in the range of 20∼120cm deep, 50∼160cm wide of the flume. In this study, the 23 different kinds of the current meter rating enabled us to determine the constants a and b of the following equation. V=an+b(m/sec) where, n is number of revolution per second(n=N/T) V is velocity(v=D/T) The above constant can be determined by the least squares method and plotting, using the velocity(V=D/T) and the number of revolution per second(n=N/T) obtained from the running distance(D), time(T), the number of revolutin(N), and the running number(m). From the experiments the following conclusions are drawn: 1) The rating flume is large enough if the flume is 110∼120cm deep, and 40∼50m long. 2) The optimum depth for rating of a current meter is in the range of h=40∼50cm.