• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.8
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• pp.315-324
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• 2020

The purpose of this study was to examine the relationship between emotional traumatic experience, stress, depression, and anxiety and to identify factors influencing suicide ideation. Data collection was carried out using a questionnaire survey administered to students from four health colleges in B city and a total of 289 questionnaires. Collected data were analyzed by frequency and percentage, mean, standard deviation, t-test, ANOVA, and multiple regression analysis using the SPSS/WIN program. The results show that there were significant differences in emotional trauma according to the general characteristics of the study subjects (p=.005) and stress related to grades (p=.029). Depression showed significant differences for gender (p=.020), religion (p=.022), and anxiety related to gender (p=.047). Suicidal thinking was not significantly different from the general characteristics. The suicidal ideation of the subjects was significantly correlated with emotional trauma (p<.001), stress (p<.001), depression (p<.001) and anxiety (p<.001). Factors affecting the suicidal ideation of the subjects were emotional trauma (t=4.117, p<.001), stress (t=2.909, p=.004), depression (t=3.421, p=.001), and anxiety (t=2.875, p=.004), and the explanatory power was 34.1%. This study can be used as basic data for the development of a suicide prevention program by identifying correlations between emotional traumatic experience, stress, depression, and anxiety related to suicide ideation and identifying factors affecting suicide ideation. Based on these results, the development of programs to reduce the college student suicide rate is necessary.

• Journal of Gastric Cancer
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• v.1 no.2
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• pp.77-82
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• 2001

Purpose: The most important prognostic factors in gastric cancer are depth of invasion and lymph node metastasis. Therefore, the prognosis for serosa and lymph node negative gastric cancer is favorable. However, there is no general agreement on the prognostic factors in this subset of patients. This study was undertaken to evaluate the prognostic significances of venous invasion (VI), lymphatic invasion (LI), and perineural invasion (NI) in T1 and T2 gastric cancer without lymph node involvement. Materials and Methods: We retrospectively evaluated 206 patients with T1 and T2, lymph node negative gastric cancer who underwent a curative resection from 1989 to 1993 at Kangnam St. Mary's Hospital, Seoul, Korea. The Chi-square test was used to determine the statistical significance of differences, and the Kaplan-Meier method was used to calculate survival rates. Significant differences in the survival rates were assessed using the log-rank test, and the Cox regression method was used to evaluate independent prognostic significance. Results: The rate of VI, LI and NI correlated well with the depth of tumor invasion. The rates of VI (+) for T1 vs T2 was $0\%\;vs\;5.1\%$, of LI (+) was $5.6\%\;vs\;26.8\%$, and of NI (+) was $1.6\%\;vs\;26.8\%$ in NI (+). There were 13 recurrent cases, 10 cases out of the 13 were T2 gastric cancers, and the recurrence rate was higher in LI (+) and NI (+) cases than in LI (-) and NI (-) cases. The 5-year survival rates were $93.4\%$ in LI (-) cases, $77.4\%$ in LI (+) cases, $92.5\%$ in NI (-) cases, $74\%$ in NI(+) cases, $95.9\%$ in LI (-) NI (-) cases, and $73.9\%$ in LI (+) NI (+) cases. Multivariate analysis demonstrated that simultaneous LI and NI was the only significant factor influencing the prognosis. Conclusion: These results suggest that simultaneous lymphatic and perineural invasion may be an independent prognostic factor in patients with T1 and T2 gastric cancer without lymph node metastasis.

• Investigative Magnetic Resonance Imaging
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• v.20 no.2
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• pp.81-87
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• 2016

Purpose: To analyze the feasibility of three-dimensional (3D) diffusion-weighted (DW) PSIF (reversed FISP [fast imaging with steady-state free precession]) sequence in order to evaluate peripheral nerves in the elbow. Materials and Methods: Ten normal, asymptomatic volunteers were enrolled (6 men, 4 women, mean age 27.9 years). The following sequences of magnetic resonance images (MRI) of the elbow were obtained using a 3.0-T machine: 3D DW PSIF, 3D T2 SPACE (sampling perfection with application optimized contrasts using different flip angle evolution) with SPAIR (spectral adiabatic inversion recovery) and 2D T2 TSE (turbo spin echo) with modified Dixon (m-Dixon) sequence. Two observers used a 5-point grading system to analyze the image quality of the ulnar, median, and radial nerves. The signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) of each nerve were measured. We compared 3D DW PSIF images with other sequences using the Wilcoxon-signed rank test and Friedman test. Inter-observer agreement was measured using intraclass correlation coefficient (ICC) analysis. Results: The mean 5-point scores of radial, median, and ulnar nerves in 3D DW PSIF (3.9/4.2/4.5, respectively) were higher than those in 3D T2 SPACE SPAIR (1.9/2.8/2.8) and 2D T2 TSE m-Dixon (1.7/2.8/2.9) sequences (P < 0.05). The mean SNR in 3D DW PSIF was lower than 3D T2 SPACE SPAIR, but there was no difference between 3D DW PSIF and 2D T2 TSE m-Dixon in all of the three nerves. The mean CNR in 3D DW PSIF was lower than 3D T2 SPACE SPAIR and 2D T2 TSE m-Dixon in the median and ulnar nerves, but no difference among the three sequences in the radial nerve. Conclusion: The three-dimensional DW PSIF sequence may be feasible to evaluate the peripheral nerves around the elbow in MR imaging. However, further optimization of the image quality (SNR, CNR) is required.

• Journal of Convergence for Information Technology
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• v.11 no.3
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• pp.220-228
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• 2021

In this study, 20 middle-aged women aged from 35 to 55 were studied from October 12, 2020 to November 15, 2020 to find out the effects of improvement of facial skin of Jinyeosoo Clean Mist. Among the 20 participants, 10 were divided into experimental group and 10 control group. The Janus facial skin scope system (PSI Co.) used on the skin to measure pore, wrinkles, elasticity, UV pigmentation, and skin tone observed depending the difference in light sources. The facial examination took place 10 minutes after cleansing to stabilize and a total of 4 examinations were carried out after every week of using Jinyeosoo Clean Mist for 4 weeks. For statistical processing, SPSS statistics program 21.0 was utilized to compare the mean averages of pre-experimental and post-experimental data from the above two groups - the experimental group that used Jinyeosoo Clean Mist (hydrogen ion mist) 1 and 2 and the control group that did not use the subject products - and the corresponding sample t-test was used. As a result of the analysis, the group that used Jinyeosoo Clean Mist showed difference in pores (t=3.280, p<.05), wrinkles (t=4.353, p<.01) and elasticity (t=3.003, p<.05), skin tone(t=3.280, p<.01) under the statistical significance level.

• The Korean Journal of Nuclear Medicine Technology
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• v.16 no.1
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• pp.115-118
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• 2012

Purpose: The Levey-Jennings chart controlled measurement values that deviated from the tolerance value (mean ${\pm}2SD$ or ${\pm}3SD$). On the other hand, the upgraded Westgard Multi-Rules are actively recommended as a more efficient, specialized form of hospital certification in relation to Internal Quality Control. To apply Westgard Multi-Rules in quality control, credible quality control substance and target value are required. However, as physical examinations commonly use quality control substances provided within the test kit, there are many difficulties presented in the calculation of target value in relation to frequent changes in concentration value and insufficient credibility of quality control substance. This study attempts to improve the professionalism and credibility of quality control by applying Westgard Multi-Rules and calculating credible target value by using a commercialized quality control substance. Materials and Methods : This study used Immunoassay Plus Control Level 1, 2, 3 of Company B as the quality control substance of Total T3, which is the thyroid test implemented at the relevant hospital. Target value was established as the mean value of 295 cases collected for 1 month, excluding values that deviated from ${\pm}2SD$. The hospital quality control calculation program was used to enter target value. 12s, 22s, 13s, 2 of 32s, R4s, 41s, $10\bar{x}$, 7T of Westgard Multi-Rules were applied in the Total T3 experiment, which was conducted 194 times for 20 days in August. Based on the applied rules, this study classified data into random error and systemic error for analysis. Results: Quality control substances 1, 2, and 3 were each established as 84.2 ng/$dl$, 156.7 ng/$dl$, 242.4 ng/$dl$ for target values of Total T3, with the standard deviation established as 11.22 ng/$dl$, 14.52 ng/$dl$, 14.52 ng/$dl$ respectively. According to error type analysis achieved after applying Westgard Multi-Rules based on established target values, the following results were obtained for Random error, 12s was analyzed 48 times, 13s was analyzed 13 times, R4s was analyzed 6 times, for Systemic error, 22s was analyzed 10 times, 41s was analyzed 11 times, 2 of 32s was analyzed 17 times, $10\bar{x}$ was analyzed 10 times, and 7T was not applied. For uncontrollable Random error types, the entire experimental process was rechecked and greater emphasis was placed on re-testing. For controllable Systemic error types, this study searched the cause of error, recorded the relevant cause in the action form and reported the information to the Internal Quality Control committee if necessary. Conclusions : This study applied Westgard Multi-Rules by using commercialized substance as quality control substance and establishing target values. In result, precise analysis of Random error and Systemic error was achieved through the analysis of 12s, 22s, 13s, 2 of 32s, R4s, 41s, $10\bar{x}$, 7T rules. Furthermore, ideal quality control was achieved through analysis conducted on all data presented within the range of ${\pm}3SD$. In this regard, it can be said that the quality control method formed based on the systematic application of Westgard Multi-Rules is more effective than the Levey-Jennings chart and can maximize error detection.

• Journal of Convergence for Information Technology
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• v.10 no.9
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• pp.244-250
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• 2020

The aim of the study is to investigate the effect of the benefit of soft waxing, hard waxing, and sugaring waxing on intention to reuse in Korean adults, and to provide useful information to people who are new to waxing. As a research method, from May 1, 2019 to August 30 (17 weeks), we surveyed 422 subjects between 10 and 40 years old who lived in Busan and Yeongnam area and experienced waxing. In statistical analysis, Cronbach's alpha was calculated for reliability test, and Chi-squared test, independent t-test, correlation analysis and linear regression analysis were used. Multiple responses were analyzed using multiple response test. In the result of the effect of waxing benefit on intention to reuse, there was a significant positive correlation of waxing seeking score by body part, total waxing benefit score(r=0.389, p<0.001), and total score of intention to reuse (r=0.214, p>0.001) with intention to reuse. There was also a significant positive correlation between waxing benefit by body part and intention to reuse, except arms and legs. In the result of the effect of waxing benefit on intention to reuse, face waxing (β=0.106, p<0.001), Brazilian waxing (β=0.221, p<0.001) and total waxing benefit score (β=0.321, p<0.001) had a significant effect on intention to reuse. In the present study, awareness of sugaring waxing was low but favor and intention to reuse were strong, and the subjects sought sugaring waxing for sensitive body parts. Thus, would provide useful information for consumers new to waxing, and also basic information for studies on waxing.

• Journal of Korean Society of Forest Science
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• v.108 no.3
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• pp.322-328
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• 2019

The purpose of this study was to provide basic data for maintenance and repair of the forest road surfaces using the light drop weight test (LDWT), density test, and grain size analysis at four sites in Yeongyang-gun Mt. (2011y, 2014y, 2016y, and 2017y). In terms of the density test results, the opening density in 2011 was the highest at $2.0694g/cm^3$, and the opening density in 2017 was the lowest at $1.7443g/cm^3$. The grain size analysis showed that the proportion of large aggregates was highest at the opening in 2017, and the proportion of large aggregates decreased with the delay of opening date. From the LDWT results, $E_{vd}$ (the dynamic deformation coefficient) of the 2011y forest road was $35.7MN/m^2$, 2014y was $30.5MN/m^2$, 2016y was $28.6MN/m^2$, and 2017y was $23.5MN/m^2$. The $E_{vd}$ value for the oldest forests opened with the 2011y forest road was the highest, the average $E_{vd}$ value of the center portion was $21.45MN/m^2$, the average $E_{vd}$ value of the wheel portion of the banking part was $31.31MN/m^2$, and the average $E_{vd}$ value of the wheel portion of the cut part was $36.71MN/m^2$.

• Korean Journal of Psychosomatic Medicine
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• v.24 no.1
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• pp.66-73
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• 2016

Objectives : The purpose of this study was to investigate the characteristics of psychosocial factors related to functional dyspepsia(FD) and their effects on quality of life(QOL) in firefighters. Methods : This study examined data collected from 1,217 firefighters. We measured psychological symptoms by Patient Health Questionnaire-9(PHQ-9), Generalized Anxiety Disorder questionnaire(GAD-7), Korean Occupational Stress Scale(KOSS), Ways of Coping checklist(WCCL), Rosenberg's Self-Esteem Scale(RSES) and World Health Organization Quality of Life Scale abbreviated version(WHOQOL-BREF). Chi-square test, independent t-test, Pearson's correlation test, logistic regression analysis, and hierarchical regression analysis were used as statistical analysis methods. Results : For the group with FD, the male participants showed significantly higher frequency(p=0.006) compared to the female participants. The group with FD had higher scores for depressive symptoms(p<.001), anxiety (p<.001), and occupational stress(p<.001), and did lower scores for self-esteem(p=.008), quality of life(p<.001) than those without FD. The FD risk was higher in the following KOSS subcategories: job demand(OR 1.94, 95% CI : 1.29-2.93), lack of reward(OR 2.47, 95% CI : 1.61-3.81), and occupational climate(OR 1.51, 95% CI : 1.01-2.24). In the hierarchical regression analysis, QOL was best predicted by depressive symptoms, self-esteem, and occupational stress. Three predictive variables above accounts for 42.0% variance explained of total variance. Conclusions : The psychosocial factors showed significant effects on FD, and predictive variables for QOL were identified based on regression analysis. The results suggest that the psychiatric approach should be accompanied with medical approach in future FD assessment.

• Journal of Global Scholars of Marketing Science
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• v.9
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• pp.1-17
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• 2002

The purposes of this study were to investigate clothing involvement and clothing information source on personality types. Personality types were applied using Myers-Briggs Type Indicator(MBTI). Clothing involvement was measured using 17 questions of 5-point scales. Clothing information source was measured using 16 items of 5-point scales. The data were collected from 275 female using questionnaire. The data analysed with frequence, factor analysis, t-test, one-way ANOVA, and Duncan test. The clothing involvement included three factors: Symbolic Expression, Pleasure and Interest, and Fashionability. The clothing information source included four factors: Printed Media, Radio Media, Professional Media and Store Search. Extroversion-introvertion and thinking-feeling index had significant difference in the dimensions of clothing involvement. Extroversion types were significantly evaluated fashionability more than introvertion types(t=2.008, p<.05). Feeling types were significantly evaluated fashionability more than thinking types (t=2.428, p<.05). Extroversion-introvertion index had significant difference in clothing information source. Extroversion types were significantly used printed media more than Introvertion types.

• Biomolecules & Therapeutics
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• v.11 no.1
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• pp.65-71
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• 2003

Terbinafine is a synthetic allylamine that is available in an oral formulation and is used at a dosage of 250mg/day. It is used as an active antifungal agent and inhibits the fungal enzyme squalene epoxidase, which leads to the accumulation of the sterol squalene, which is toxic to the organism. The purpose of the present study was to evaluate the bioequivalence of two terbinafine tablets, Lamisil (Novartis Korea Ltd.) and Terbinex (C-TRI Ltd.), according to the guidelines of Korea Food and Drug Administration (KFDA). Eighteen normal male volunteers, 26.00$\pm$2.57 year in age and 70.51$\pm$9.36 kg in body weight, were divided into two groups and a randomized 2${\times}$2 cross-over study was employed. After one tablet containing 125 mg of terbinafine was orally administered, blood was taken at predetermined time intervals and the concentrations of terbinafine in plasma were determined using HPLC with UV detector. Pharmacokinetic parameters such as AUC, $C_{max}$ and $T_{max}$ were calculated and ANOVA test was utilized for the statistical analysis of the parameters. The results showed that the differences in AUC, $C_{max}$ and $T_{max}$ between two tablets were －4.191％, 5.223％ and －25.720％, respectively when calculated against the Lamisil, tablet. The powers (1-$\beta$) for AUC, $C_{max}$ and $T_{max}$ were 81％, 87％ and below 60％, respectively. Minimum detectable differences(.il) at alpha=O.1 and 1-/3=0.8 were less than 20％ (e.g., 19.72％ and 17.77％ for AUC and $C_{max}$, respectively). But minimum detectable differences($\Delta$) at alpha=0.1 and 1-$\beta$=0.8 for $T_{max}$ were more than 20％ (e.g., 26.25％). The 90％ confidence intervals were within $\pm$20％ (e.g., －17.440∼9.06 and －6.713∼17.160 for AUC and $C_{max}$ respectively). But 90％ confidence intervals for $T_{max}$ were not within $\pm$20％ (e.g., －43.346∼8.083). Another ANOVA test was conducted for logarithmically transformed AUC and $C_{max}$. These results showed that there are no significant differences in AUC and $C_{max}$ between the two formulations: The differences between the formulations in these log transformed parameters were all for less than 20％ (e.g., －4.19％ and 5.22％ for AUC and $C_{max}$, respectively). The 90％ confidence intervals for the log transformed data were not the acceptance range of log 0.8 to log 1.25 in AUC but the acceptance range of log 0.8 to log 1.25 in $C_{max}$ (e.g., log 1.13∼log 1.50 and log 0.94-log 1.22 for AUC and $C_{max}$ respectively). The major parameters, AUC and $C_{max}$ met the criteria of KFDA for bioequivalence although $T_{max}$ did not meet the criteria of KFDA (1998 year) for bioequivalence, indicating that Onfran tablet is bioequivalent to Zofran tablet. But in another ANOVA test AUC did not meet the criteria of KFDA (2002) for bioequivalence but $C_{max}$ met the criteria of KFDA (2002 year) for bioequivalence.or bioequivalence.equivalence.equivalence.equivalence.