• Transactions on Electrical and Electronic Materials
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• v.9 no.1
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• pp.38-43
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• 2008

Using an arterial pressure-volume (APV) model, we performed an analysis of the conventional blood pressure estimation method using an oscillometric sphygmomanometer with computer simulation. Traditionally, the maximum amplitude algorithm (MAA) has been applied to the oscillation waveforms of the APV model to obtain the mean arterial pressure and the characteristic ratio. The estimation of mean arterial pressure and characteristic ratio was significantly affected by the shape of the blood pressure waveforms and the cutoff frequency of high-pass filter (HPF) circuitry. Experimental errors result from these effects when estimating blood pressure. To determine an algorithm independent of the influence of waveform shapes and parameters of HPF, the volume oscillation of the APV model and the phase shift of the oscillation with fast Fourier transform (FFT) were tested while increasing the cuff pressure from 1 mmHg to 200 mmHg (1 mmHg/s). The phase shift between ranges of volume oscillation was then only observed between the systolic and the diastolic blood pressures. The same results were obtained from simulations performed on two different arterial blood pressure waveforms and one hyperthermia waveform.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.16 no.4
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• pp.1209-1223
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• 2022

Blood pressure is one of the key physiological parameters for determining human health, and can prove whether human cardiovascular function is healthy or not. In general, what we call blood pressure refers to arterial blood pressure. Blood pressure fluctuates greatly and, due to the influence of various factors, even varies with each heartbeat. Therefore, achievement of continuous blood pressure measurement is particularly important for more accurate diagnosis. It is difficult to achieve long-term continuous blood pressure monitoring with traditional measurement methods due to the continuous wear of measuring instruments. On the other hand, radar technology is not easily affected by environmental factors and is capable of strong penetration. In this study, by using machine learning, tried to develop a linear blood pressure prediction model using data from a public database. The radar sensor evaluates the measured object, obtains the pulse waveform data, calculates the pulse transmission time, and obtains the blood pressure data through linear model regression analysis. Confirm its availability to facilitate follow-up research, such as integrating other sensors, collecting temperature, heartbeat, respiratory pulse and other data, and seeking medical treatment in time in case of abnormalities.

• Journal of Environmental Health Sciences
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• v.17 no.2
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• pp.48-53
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• 1991

This study was carried out to investigate age, noise intensity, work period, hearing loss at frequencies, hypertension and to examine correlation of the total quantity of noise exposure(Dose) and blood pressure (Response) in the auto industry during May 1987-December 1987. To perform this study 65 workers were tested. Results of this study were as follows: 1. In frequency analysis, the CS-dip phenomenon occurred around 4000 Hz. 2. Between under of ten years group and over of ten years group, average hearing loss value was statitically significant (P < 0.05). 3. The prevalence of hypertension of 65 workers was 7.84% . 4. At 90dB(A) over and 10 years under and workers in the 20's group, the total quantity of noise exposure (Dose) and systolic blood pressure (Response) were statistically significant (P < 0.05). 5. At under 10 years of work period group, the total quantity of noise exposure(Dose) and diastolic blood pressure (Response) were statistically significant(r =0.234, P < 0.1).

• Journal of Nutrition and Health
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• v.37 no.7
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• pp.509-514
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• 2004

This study was conducted to investigate the supplementary effects of Lentinus edodes on blood pressure and blood lipid levels in the Hypertensive Rat. We supplied 3 kinds of experimental diets (Control; CO, cap of Lentinus edodes; LC, and stipe of Lentinus edodes; LS) to spontaneously hypertensive rats (SHR) for 8 weeks. Diet intake, body weight, organ weights, and serum lipid levels were measured. There was no significant difference in diet intake, and body, liver and epididymal fat pad weights among experimental groups. The levels of systolic and diastolic blood pressure were significantly lower in LC and LS groups than CO group. The concentrations of serum total cholesterol were lower in LC and LS groups than CO group. These results suggested that Lentinus edodes decrease blood pressure levels and serum total cholesterol concentration in the spontaneously hypertensive rats. But these effects of Lentinus edodes didn't show any significant difference between animals fed cap and stipe of this mushroom.

• Biomolecules & Therapeutics
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• v.10 no.2
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• pp.89-98
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• 2002

In this study general pharmacological profiles of KI-60606 on the central nervous system, the cardiovascular system and the other organs were investigated. The dosages given were 0,5, 10 and 25 mg/kg and drugs were administered intravenously. The animals used for this study were mice, rats, cats and guinea pigs. KI-60606 showed no effects on general behavior, motor coordination, spontaneous locomotor activity, hexobarbital-induced hypnosis time, body temperature, analgesic activity, anticonvulsant activity and contraction of nictitating membrane in cats. Furthermore KI-60606 showed no effects on blood pressure, heart rate, LVP (left ventricular peak systolic pressure), LVEDP (left ventricular end diastolic pressure), LVDP (left ventricular developing pressure), DP(double product), CFR(coronary flow rate), smooth muscle contraction using guinea pig ileum and gastric secretion at all dosage tested except the increase of gastrointestinal transport and urinary $K^+$ excretion.

• Proceedings of the Korean Environmental Health Society Conference
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• 2003.06a
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• pp.166-170
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• 2003

Smoking of tobacco cigarettes is associated with a rise in blood pressure together with an increase in heart beat rate. This study examined the acute effect of tobacco and non-tobacco cigarette smoking on the blood pressure and heart beat rate by randomized crossover study involved 39 volunteers. In the results, systolic blood pressure and heart beat rate changes after smoking were significantly different in non-tobacco cigarette smoking group from in tobacco cigarette smoking group.

• Toxicological Research
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• v.19 no.1
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• pp.29-31
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• 2003

It has been reported that the genetic variations in the Y chromosome has influence the blood pressure in some Caucasian male populations, but the effect in non-Caucasian population is unclear. In the present study, we examined the relationship between blood pressure and a HindIII RFLP of Y chromosome in 152 unrelated male individuals of ethnically homogeneous Korean origin. There were no significant differences in systolic and diastolic blood pressures between genotype groups, respectively. However, the frequency of A genotype in Korean population was much higher than those of Caucasian populations (P＜0.05). Therefore, the results of this study will con-tribute the better understanding the genetic characteristics of Y chromosome in Korean population.

• Biomolecules & Therapeutics
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• v.7 no.2
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• pp.170-177
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• 1999

PEG-hemoglobin SB1 (SB1), which is a hemoglobin-based oxygen carrier, is intended to use as a safe blood substitute against brain ischemia and stroke. The general pharmacological profiles of SB1 were studied. The doses given were 0, 5, 10, 20 ml/kg and drugs were administered intravenously. The animals used for this study were mouse, rat and guinea pig. SB1 showed no effects on general behavior, motor coordination, spontaneous locomotor activity, hexobarbital sleeping time, anticonvulsant activity, analgesic activity, blood pressure and heart rate, left ventricular peak systolic pressure, left ventricular end diastolic pressure, left ventricular developing pressure, double product, heart rate, coronary flow rate, smooth muscle contraction using guinea pig ileum, gastrointestinal transport, gastric secretion, urinary volume and electrolyte excretion at all doses tested except the decrease of body temperature. These findings demonstrated that SB1 possesses no general pharmacological effects at all doses tested.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.61 no.11
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• pp.1720-1724
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• 2012

This study describes an oscillometric-based blood pressure measuring algorithm by detecting turning points of oscillation signal from digitally filtered cuff signals of an automatic sphygmomanometer. The blood pressure measuring algorithm uses a characteristic ratios method from the turning points. The accurate values of the systolic/diastolic blood presures(SBP/DBP) are calculated using the peaks in the ranges of characteristic ratios. Performances of the proposed algorithm and four automatic sphygmomanometers are compared with the mercury manometer(manual type sphygmomanometer), regarding the SBP and DBP values of manual sphygmomanometer as the reference values. The performance test showed the proposed algorithm revealed the best results in errors and a statistical analysis. Therefore this algorithm can be usable in any automatic sphygmomanometers.ssure states. This may be compromising results for subject-independent sensibility evaluation using EEG signal.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.34 no.2
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• pp.131-134
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• 2008

Purpose: The objective of this study was to evaluate the clinical parameters in terms of the midazolam sedation in patients undergoing dental practice. Patients and Methods: Total 28 patients were included in this study. They received the dental practice in the daycare center and sedation was done with midazolam. The recorded variables were blood pressure, pulse rate, $SpO_2$, and patient's response. The differences between observations were analyzed with paired samples t-test. Results: The blood pressure was significantly decreased after the administration of midazolam and the systolic pressure was significantly increased at the start of operation (P<0.05). The pulse rate was significantly increased after lidocaine injection (P<0.001). The amnesic effect was shown 21 cases out of 28 cases (75%). Conclusions: The effect of midazolam on pulse rate was not significant. However, midazolam could decrease the blood pressure significantly. Therefore, the sedation with midazolam could be successfully used in the dental practice, particularly for the patients having the hypertension.