• Journal of the Korean Society of Radiology
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• v.82 no.3
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• pp.575-588
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• 2021

Immunoglobulin G4 (IgG4)-related disease is a systemic fibro-inflammatory disease characterized by pathologic findings in various organs. Imaging is critical for the diagnosis and treatment assessment of patients with IgG4-related disease. In this pictorial essay, we review the key features of multiple imaging modalities, typical pathologic findings, and differential diagnosis of IgG4-related disease. This systematic pictorial review can further our understanding of the broad-spectrum manifestations of this disease.

• Journal of Radiation Industry
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• v.17 no.4
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• pp.391-396
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• 2023

Currently, state-of-the-art devices such as SPECT, PET/CT, and PET/MRI are rapidly spreading nationwide, and the penetration rate of nuclear medical devices is also ranked fifth in the world. However, PET/MRI's system is slower and less common because it is more complex than PET/CT. The purpose of this study is to provide optimal information on PET/MRI according to the patient's disease. The subjects obtained information on head and neck cancer, pediatric patients, breast cancer patients, heart disease patients, lung cancer patients, and rectal cancer patients. We tried to accumulate protocols by obtaining a lot of information about each disease. In diagnosing head and neck cancer, it is believed that it is highly likely to be used in evaluating preoperative stage determination, recurrence and remote metastasis after treatment, and unclear primary cervical lymph node metastasis. Diagnosis and continuous follow-up of pediatric patients can increase patient benefits by minimizing radiation exposure. Breast cancer provides a comprehensive evaluation of the clinical need to determine the extent of disease in breast and local lymph nodes and the systematic stages of early diagnosis or recurrence. In diagnosing heart disease patients, MR-based PET motion correction helps to realize the full potential of PET images. For lung cancer patients, the clinical value and usefulness of the resolution and detection ability of integrated PET/MRI for soft tissues such as lung cancer will be sufficient. In diagnosing rectal cancer patients, the detection of missing residual diseases can change the clinical response evaluation for rectal cancer patients treated with TNT, and both the initial stage and treatment response evaluation are possible. Therefore, this literature study provided basic clinical data for PET/MRI tests.

• Journal of Oriental Neuropsychiatry
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• v.28 no.4
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• pp.319-332
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• 2017

Objectives: The present study aimed to provide clinical evidence on the effect of herbal medicine, Hyeolbuchukeo-tang or Xuefu Zhuyu decoction for the treatment of primary insomnia using a systematic review and meta-analysis of randomized controlled trials (RCTs). Methods: This study included RCTs that verified the effects of Hyeolbuchukeo-tang or Xuefu Zhuyu decoction for the treatment of primary insomnia. Literature searches of English, Chinese and Korean databases were performed, and the selected literature was assessed for investigating the risk of bias. Results: The analysis included 10 RCTs. The Chinese Classification of Mental Disorders-3 was most frequently used to define the diagnostic criteria for Hyeolbuchukeo-tang or Xuefu Zhuyu decoction intervention in patients with primary insomnia. The effective rate was the most commonly used outcome measure. A meta-analysis revealed that the effective rate, the Pittsburgh Sleep Quality Index, and the Athens Insomnia Scale in the Modified Xuefu Zhuyu decoction (MXZD) group were higher compared to Western Medicine (WM) group (RR: 1.17, 95% Cl: 1.08 to 1.26, p<0.0001, $I^2$=0/MD: -1.29, 95% Cl: -2.09 to -0.49, p=0.002, $I^2$=0%/MD: -0.99, 95% Cl: -1.81 to -0.18, p=0.02, $I^2$=15%). The effective rate of the MXZD+WM group was significantly different compared to the WM group (RR: 1.28, 95% Cl: 1.11 to 1.47, p=0.0006, $I^2$=2%). The included RCTs were of relatively poor quality and had small sample sizes. Conclusions: Treatment with Hyeolbuchukeo-tang or Xuefu Zhuyu decoction was found to be effective in treating primary insomnia. However, the included RCTs were of relatively poor quality and had small sample sizes. It is hypothesized that this study could serve as a foundation for further clinical studies on the development of diagnosis and treatment methods for primary insomnia based on Korean medicine.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.22
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• pp.9879-9884
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• 2014

Aim: The purpose of the current study was to conduct a systematic review of the published literature to evaluate the diagnostic accuracy of FDG-PET, PTE/CT, MRI and scintigraphy for multiple myeloma related bone disease. Methods: Through a search of PubMed, EMBASE, and the Cochrane Library, two reviewers independently assessed the methodological quality of each study. We estimated pooled sensitivity, specificity, positive and negative likelihood ratios (PLR and NLR), and two sample Z-tests were conducted to evaluate for differences in sensitivity, specificity, area under the curve (AUC), and the $Q^*$ index between any two diagnostic modalities. Results: A total of 17 studies were reviewed. The MRI had a pooled sensitivity of 0.88, specificity of 0.68, AUC of 0.897, and $Q^*$ index of 0.828, whereas for MIBI, the corresponding values were 0.98, 0.90, 0.991, and 0.962, respectively, and for bone scan, they were 066, 0.83, 0.805, and 0.740, respectively. The corresponding values of MIBI were 0.98, 0.90, 0.991, and 0.962, respectively. For PET and PET/CT, the values were 0.91, 0.69, 0.927 and 0.861, respectively. Statistically significant differences were not found in the sensitivity, specificity, AUC, and $Q^*$ index between MRI, scintigraphy, FDG-PET and PET/CT. Conclusions: On the condition that X ray is taken as a reference in our study, we suggested that FDG-PET, PTE/CT, MRI and scintigraphy are all associated with high detection rate of bone disease in patients with MM. Thus, in clinical practice, it is recommended that we could choose these tests according to the condition of the patient.

• Journal of Physiology & Pathology in Korean Medicine
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• v.29 no.6
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• pp.458-466
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• 2015

The purpose of this study was to review the research on treating depression in Traditional Chinese Medicine(TCM) over the last 5 years to set the foundation for further studies. We searched for and analyzed articles about depression in CNKI(China National Knowledge Infrastructure) from January 2010 to December 2014. The results were as follows : The most frequently used diagnostic criteria was CCMD-3(The Chinese Classification of Mental Disorders-3), and the most used evaluation criteria was HAMD(Hamilton Depression Rating Scale). Prescription of decoction of medical herbs was most frequently used as a therapeutic method. Acupuncture, traditional Chinese psychotherapy, and music therapy were also used for some studies. The most frequent TCM Syndrome Differentiation Type was stagnation of liver-QI. For decoction of Chinese herbs, Soyo-san(Xiaoyao-san) and Sihosogan-san(Chaihushugan-san) were most often prescribed, and Bupleuri Radix, Paeoniae Radix Alba, Curcumae Radix, Poria cocos wolf, Angelicae Gigantis Radix, Atractylodis Rhizoma Alba were mainly used for medical herbs. BaekHoi(GV20) and Yindang(Ex-HN3) were often used as acupuncture sites. Post-Stroke Depression was the most common case of intercurrent or secondary depression. According to the Jadad Quality Assessment Scale, the quality of the reports was not high as most of the reports had a score of 3 or below. Most systematic reviews on depression were conducted by Chinese researchers. The problem with Clinical research on depression, according to those reviews, was that there were no standardized criteria for the diagnosis and treatment and the trials were usually not randomized nor controlled. We found out there are various clinical methods for treating depression in TCM, and hope that this research could provide the preliminary data for designing and conducting clinical trials for depression.

• The Journal of Korean Academy of Sensory Integration
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• v.17 no.3
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• pp.46-60
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• 2019

Objective : The purpose of this study is to provide evidence for a systematic analysis of occupational therapy evaluations and interventions for the activities of daily living of children and adolescents. Methods : The research period was from 2010 to September 2019. The articles were collected from the Research Information Sharing Service (RISS) and Koreanstudies Information Service System (KISS) databases. The key words were 'pediatric occupational therapy & activities of daily living', 'pediatric occupational therapy & self care', 'pediatric occupational therapy & self management', 'pediatric occupational therapy & occupation', 'occupational therapy & eating', 'occupational therapy & AMPS (Assessment of Motor and Process Skills)', 'occupational therapy & WeeFIM (Functional Independence Measure for children'. Results : A total of 14 studies were analyzed, the qualitative level IV, V of the study was 72% of the total research. The diagnosis of participants included 50% intellectual disorder and 20% brain lesion, including cerebral palsy. The most frequently used method to assess the activities of daily living was Canadian Occupational Performance Measure (COPM). The most frequently used method to therapy was sensory integration therapy. The intervention effect of all studies was positive, however, the use of group programs on the occupational therapy on children with intellectually disorder didn't work. Conclusion : In Korea, there are no articles that systematically analyze whether occupational therapy improves the activities of daily living in children and adolescents.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2004.05a
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• pp.41-44
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• 2004

Recently, in the case of domestic, for all that the deterioration environment about the carbonation of reinforced concrete structures is accelerated, systematic diagnosis and researches are not completed. And the selection techniques of repair material and method used under the situation that the indicator and the performance evaluation method are nor established are dependant on existing experience. Therefore, the purpose of this study is intend to present fundamental data for the reasonable selection of repair material and method. durability design and longevity on the deteriorated reinforced concrete structures, through computing the carbonation depth and velocity coefficient by accelerating carbonation test under various accelerating conditions and investigating the application of carbonation evaluation method. The results of this study are as follow; The resistances to carbonation are increased when the W/C ratio if lower and the treatment of surface coating is executed. And the carbonation depth and velocity coefficient according to accelerating carbonation test conditions are increased when the conditions of temperature, relative humidity and $CO_2$density are higher individually.

• Korean Journal of Computational Design and Engineering
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• v.15 no.2
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• pp.94-105
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• 2010

Todays, there is fast transition about the new manufacturing IT methodologies from the conceptual phase into the practical application phase for the strengthening of enterprise competitiveness in manufacturing industry. One of those new methodologies is PLM (Product Life-cycle Management). PLM methodology consists of 3D CAD for the product design, PDM (Product Data Management) for the data management based on the collaboration platform and lastly DM (Digital Manufacturing). DM has evoluted from the stand-alone computer simulation of early 1980s, and now it covers the overall production development and production. Unfortunately, there exist serious critical problems about the actual application of DM for the real work. This is owing to the transition of the point of view from stand-alone type application (such as flow simulation or robot simulation) to that of business process about product development and production management. In this paper, we propose an application framework for the successful project with the digital manufacturing methodology with the concept of Information Strategy Planning, which enables the systematic diagnosis and the quantitative evaluation. Also, we introduce the actual practice of the proposing framework with the ISP project for 'Analysis & Simulation Technique of manufacturing process project' that is being conducted by Chungnam Techno Park.

• Journal of Sensor Science and Technology
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• v.15 no.2
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• pp.77-83
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• 2006

A monitoring apparatus for pulse shapes of human heartbeats has been developed using an amorphous MI(Magnetic Impedance) sensor. The pulse shapes are successfully obtained from voltage signals due to the variations of magnetic impedance in the amorphous MI sensor, which is attached to a patient's wrist. This voltage signal was fed into a signal processing module to extract the pulse shapes of heartbeats. The signal processing module, which is proposed to detect a weak variations of impedance in MI sensor under a noisy measurement environment, consists of a high frequency current source, an amplifier stage and a synchronous detection circuit. To evaluate the characteristics of a newly developed apparatus, various experiments were performed. The experimental results show that the developed apparatus could be used as a diagnosis tool for traditional Korean medicine with further systematic clinical studies.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.1 no.1
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• pp.65-76
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• 1990

Behavioral characteristics of Attention Deficit Hyperactivity Disorder (ADHD) are aften observed in normal children. As a result, it is at times difficult to distinguish behavior disorder of clinical significance and normal developmental phenomenon. In addition, symptoms of ADHD can vary greatly depending on situations and social context, creating considerable difficulties in assessment. Therefore it is important to obtain information from various sources and in diverse situations. It is also desirable to quantify the severity of the problems whenever possible and determine their clinical significance by comparing the data to developmental norms. Specifically, various assessment methods such as interview with parent and child, behavior rating scales, behavioral observation and psychological testing were reviewed with discussion on merits and limitatious of each. It was emphasized that systematic and comprehensive assessment utilizing appropriate methods is necessary for accurate diagnosis and treatment evaluation of ADHD.