• Title/Summary/Keyword: System Risk Analysis

Search Result 2,524, Processing Time 0.037 seconds

The Factors of Affecting on the Health-related Quality of Life for Young-Old and Old-Old in Women Living Alone (전후기 여성 독거노인의 건강관련 삶의 질 영향 요인)

  • Kim, Hyang-Soo
    • Journal of the Korean Applied Science and Technology
    • /
    • v.36 no.1
    • /
    • pp.59-72
    • /
    • 2019
  • This is the study of descriptive research to look into factors which influence the health-related quality of life for young-old and old-old in women living alone. This research was conducted using the primary data from 2017 -Influences on the quality of health-related life based on pain, nutritional risk, loneliness, and cognitive health condition in women living alone- and the secondary analysis which additionally collected from total 85 cases. According to the analyzed result using SPSS/W IN 18. program, the factors of affecting on the health-related quality of life is followed by pain, regular exercise, and social support for young-old women living alone and regular exercise, activities of Daily Living, and pain for old-old women living alone. The explanatory power was 70.6 percent and 69.7 percent respectively. Thus, it is necessary to improve the health-related quality of life by seeking ways to alleviate pain, enhance the system of social support, activate daily exercise, and maintain the ability of routine activities.

Novel Discovery of LINE-1 in a Korean Individual by a Target Enrichment Method

  • Shin, Wonseok;Mun, Seyoung;Kim, Junse;Lee, Wooseok;Park, Dong-Guk;Choi, Seungkyu;Lee, Tae Yoon;Cha, Seunghee;Han, Kyudong
    • Molecules and Cells
    • /
    • v.42 no.1
    • /
    • pp.87-95
    • /
    • 2019
  • Long interspersed element-1 (LINE-1 or L1) is an autonomous retrotransposon, which is capable of inserting into a new region of genome. Previous studies have reported that these elements lead to genomic variations and altered functions by affecting gene expression and genetic networks. Mounting evidence strongly indicates that genetic diseases or various cancers can occur as a result of retrotransposition events that involve L1s. Therefore, the development of methodologies to study the structural variations and interpersonal insertion polymorphisms by L1 element-associated changes in an individual genome is invaluable. In this study, we applied a systematic approach to identify human-specific L1s (i.e., L1Hs) through the bioinformatics analysis of high-throughput next-generation sequencing data. We identified 525 candidates that could be inferred to carry non-reference L1Hs in a Korean individual genome (KPGP9). Among them, we randomly selected 40 candidates and validated that approximately 92.5% of non-reference L1Hs were inserted into a KPGP9 genome. In addition, unlike conventional methods, our relatively simple and expedited approach was highly reproducible in confirming the L1 insertions. Taken together, our findings strongly support that the identification of non-reference L1Hs by our novel target enrichment method demonstrates its future application to genomic variation studies on the risk of cancer and genetic disorders.

Patient Safety Culture, Perception of Importance on Patient Safety Management, and Patient Safety Management Activities of Care Workers in Nursing Homes: Mixed-method Approach (노인요양시설 요양보호사의 환자안전문화, 환자안전관리 중요성 인식 및 환자안전관리활동: 혼합연구방법 적용)

  • Kim, Soon Ock;Kim, Jeong Ah
    • Journal of Korean Public Health Nursing
    • /
    • v.34 no.3
    • /
    • pp.473-489
    • /
    • 2020
  • Purpose: This study investigated the patient safety culture (PSC), the perception of importance on patient safety management (PIPSM) and the patient safety management activities (PSMA) of care workers in nursing homes. This was a descriptive study that attempted to provide basic data for the patient safety education program of care workers. Methods: Data were collected using questionnaires and interviews from July 1 to 31 in 2020. One hundred and seventy-four care workers participated in quantitative research. The collected data were analyzed by the SPSS/WIN 25.0 program using descriptive statistics, t-test, ANOVA, Bonferroni, and Pearson's correlation. The qualitative data were collected through semi-structured, audio-recorded interviews with six representatives and six care workers from six nursing homes. Content analysis was performed to analyze the data. Results: Positive correlations were observed between PSC and PIPSM, and between PIPSM and PIPSM. Care workers' experience in patient safety management was in the following six categories: "Safety accident risk factors", "Type of safety accidents", "How to prevent safety accidents", "Effective safety management education", "Emphasis on occupational ethics of care workers", and "Needs for standard protocol" Conclusion: These findings indicate that considering the care workers' age and facility size, nurses should enhance patient safety education for care workers and establish a management activity system.

Preparedness of food industry in korea for united states food and drug administration food safety modernization act (미국 식품의약품안전청 식품안전 현대화법에 대한 국내 식품산업의 대처 방안)

  • Kim, Jang Ho;Eun, Jong-Bang
    • Food Science and Industry
    • /
    • v.49 no.3
    • /
    • pp.55-61
    • /
    • 2016
  • Even though the food safety system in the United States is one of the best in the world, many millions of people become sick and thousands die from foodborne illnesses caused by any of a number of microbial pathogens and other contaminants. Large recalls of United States Department of Agriculture (USDA) and the Food Drug and Administration (US FDA)-regulated food products due to findings of E. coli O157:H7, Listeria, Salmonella, and other problems occur each year. As the US FDA Food Safety Modernization Act (FSMA) passed in 2011, FSMA will require food processing, manufacturing, shipping, and other regulated entities to conduct an analysis of the most likely safety hazards and to design and implement risk-based controls to reduce or eliminate these hazards. FSMA also mandates increased scrutiny of food imports, which account for a growing share of U.S. food consumption; food import shipments will have to be accompanied by documentation showing that they can meet safety standards that are at least equivalent to those in the U.S. On September 17, 2015, the US FDA published final rules for Preventive Controls for Human and Animal Food and, continuing into 2016, the US FDA intends to finalize the remaining five rules it has proposed to implement FSMA. Among these rules, this article will review and discuss Preventive Controls for Human Food Rule and its components, and suggest how to comply with these FSMA rules as foreign human food and ingredients suppliers to the US.

A Study on the Blockchain-Based Insurance Fraud Prediction Model Using Machine Learning (기계학습을 이용한 블록체인 기반의 보험사기 예측 모델 연구)

  • Lee, YongJoo
    • Journal of Convergence for Information Technology
    • /
    • v.11 no.6
    • /
    • pp.270-281
    • /
    • 2021
  • With the development of information technology, the size of insurance fraud is increasing rapidly every year, and the method is being organized and advanced in conspiracy. Although various forms of prediction models are being studied to predict and detect this, insurance-related information is highly sensitive, which poses a high risk of sharing and access and has many legal or technical constraints. In this paper, we propose a machine learning insurance fraud prediction model based on blockchain, one of the most popular technologies with the recent advent of the Fourth Industrial Revolution. We utilize blockchain technology to realize a safe and trusted insurance information sharing system, apply the theory of social relationship analysis for more efficient and accurate fraud prediction, and propose machine learning fraud prediction patterns in four stages. Claims with high probability of fraud have the effect of being detected at a higher prediction rate at an earlier stage, and claims with low probability are applied differentially for post-reference management. The core mechanism of the proposed model has been verified by constructing an Ethereum local network, requiring more sophisticated performance evaluations in the future.

A Study on the Evaluation of Importance of Factors Affecting the Vessel Value (선박가치 변화요인에 관한 중요도 평가 연구)

  • Choi, Jung-Suk;Namgung, Ho
    • Journal of the Korean Society of Marine Environment & Safety
    • /
    • v.28 no.1
    • /
    • pp.91-99
    • /
    • 2022
  • The shipping industry is a service industry that operates its business by transporting cargo on ships and receiving freight. Therefore, large-scale capital investment is required for ship operation, and if the value of the ship is uncertain, the risk of shipping management increases. This study aims to identify the factors affecting changes in ship value and to analyze the importance of each variable. To achieve the goal, the factors affecting changes in ship value were identified and structured using the techniques of text mining and topic modeling, and classified into three main factors and 12 sub-factors. This study used AHP analysis to examine the relative importance of each factor. Results indicated that the main factor influencing the change in the vessel value was the shipping factor, followed by the investment factor and the environment factor. Other auxiliary factors that substantially affect the ship value include the volatility of the shipping market and of shipping freight.

Effects of Herbal Medicines on Osteoporosis in Rheumatoid Arthritis: Study Protocol for a Systematic Review and Meta-Analysis (한약이 류마티스 관절염 환자의 골다공증에 미치는 영향: 체계적 문헌 고찰 및 메타분석을 위한 프로토콜)

  • Kwon, Do Young;Gu, Ji Hyang;Lee, Eun Jung
    • Journal of Korean Medicine Rehabilitation
    • /
    • v.32 no.3
    • /
    • pp.77-84
    • /
    • 2022
  • Objectives This study is designed to identify the effectiveness of herbal medicine for osteoporosis in rheumatoid arthritis. Methods We will investigate 10 databases, 4 Korean databases (KoreaMed, KMBASE, Koreanstudies Information Service System [KISS], ScienceOn) and 6 of abroad (PubMed, EMBASE, Cochrane Library, China National Knowledge Infrastructure [CNKI], WanFang, Citation Information by NII [CiNii]) without publication date, language limitation for clinical study of herbal medicine for osteoporosis in rheumatoid arthritis. Type, dose, duration, frequency of herb medicine will be analyzed. Results Randomized controlled trials about herbal medicine or herb extract for osteoporosis in rheumatoid arthritis should be included in the study. Cochrane's risk of bias tools will be used to assess quality of the study. Mean differences or standardized mean differences of 95% confidence intervals will calculated and data synthesis will be conducted using Review Manager (RevMan, ver.5.3; The Nordic Cochrane Centre, The Cochrane Collaboration, Copenhagen, Denmark). Conclusions It is expected to provide basic data for the active use of herb medicine by systematically synthesizing and analyzing the actual situation, effectiveness, and safety of herb medicine for osteoporosis in rheumatoid arthritis.

Review on the Objective Effect and Mechanism Studies of Herbal Medicine, Acupuncture and Moxibustion Treatment for Irritable Bowel Syndrome Patients (과민성 대장증후군 환자를 대상으로 수행된 한약 및 침구치료의 객관적 효과와 기전 연구에 대한 문헌고찰)

  • Noh, Hyun Deok;Kim, Min Jeong;Cho, Im Hak;Kim, So Yeon
    • Journal of Physiology & Pathology in Korean Medicine
    • /
    • v.35 no.5
    • /
    • pp.199-209
    • /
    • 2021
  • The purpose of this study was to explore objective indicators(outcomes) which are used to evaluate clinical efficacy and figure out the mechanisms of herbal medicine, acupuncture and moxibustion treatment for Irritable bowel syndrome(IBS). We searched randomized controlled trials(RCTs) that mediated with herbal medicine, acupuncture and moxibustion treatment for IBS and used objective indicators for outcome from November 1, 2020 to December 31, 2020. The RCTs that were published in Korean, English and Chinese were included in this study. The selected literatures were analyzed about methods of result measurement and assessed by Cochrane's risk of bias(RoB). Total 18 RCTs were included in this study. There were lots of objective indicators for result measurement; the concentration of hormones in blood and neurotransmitters, the sensitivity of rectum, the functional assessment of central nerve and autonomic nerve system, the change of intestinal flora, the concentration of serum cytokines. Various objective indicators can be used to evaluate the clinical efficacy of with herbal medicine, acupuncture and moxibustion treatment for IBS, but due to the limitations of the quality of the included studies, systematic review and meta-analysis will be needed.

Differences in Users' Insights and Increase in The Acceptance Level for Using The BYOD Approach in Government, Non-Profit Organizations, and Private Sectors in Saudi Arabia

  • Alghamdi, Ahmed M.;Bahaddad, Adel A.;Almarhabi, Khalid A.
    • International Journal of Computer Science & Network Security
    • /
    • v.22 no.7
    • /
    • pp.332-346
    • /
    • 2022
  • Digital transformation represents one of the main obstacles facing several government, private, and non-profit sectors that help stabilize digital transformation in the Arabic region. One of the helpful ways to improve the level of freedom, productivity, and flexibility among employees to accept the BYOD approach is using their own devices to perform their work both in and outside the workplace. This study focuses to present the differences between the main three economic sectors, which represent the most important pillars of the economy in Saudi Arabia within the Kingdom's Vision 2030. BYOD also has great importance to the stakeholders for raising their awareness by expressing the implications, if the concept of BYOD is widely and correctly adopted. The study uses the diffusion of innovation (DOI) framework and quantitative analysis data to determine the main dimensions and important factors that help increase the awareness of the target audience. The number of participants in this study was 830, and the participants are mixing between the government, private, and non-profit sectors. The main findings showed a significant impact of several factors such as the importance of knowledge, ease of use, employee satisfaction, risk awareness, and attention to increase the level of acceptance in three main sectors study for using the BYOD approach widespread and professional use.

Effects of Oral Health Behavior and Mental Health on Metabolic Syndrome in Korean Adults

  • Jung, Jin-Ah;Cheon, Hye-Won;Moon, Sang-Eun;Hong, Sun-Hwa
    • Journal of dental hygiene science
    • /
    • v.22 no.2
    • /
    • pp.90-98
    • /
    • 2022
  • Background: Integrated management of general, mental, and oral health is necessary to improve an individual's quality of life. This study aimed to identify the effects of mental and oral health behaviors on metabolic syndrome. Methods: A total of 4,227 Korean adults aged 20 years or older were selected as study subjects using raw data from the first year (2019) of the 8th period of the Korea National Health and Nutrition Examination Survey (KNHANES). A complex sample chi-square test and a complex sample logistic regression analysis were performed using the PASW Statistics ver. 18.0 program. Results: The effect on metabolic syndrome was significantly higher in male than in 1.833 times in male, 2.914 times in 30~49 years old, and 3.855 times in 50~64 years old, and 3.929 times in people over 65 years old compared to 20~29 years old, and compared to those with a college degree or higher, those with a middle school degree or lower are 2.116 times, those with lower income levels are 1.507 times higher, those with middle-lower are 1.359 times higher, those with middle-high are 1.401 times. Compared to non-smokers, smokers were 1.570 times higher than non-smokers and compared to those without speech problem and chewing difficulty, they were 1.717 times and 1.397 times higher, respectively and 1.973 times higher in those with 0~1 brushing times per day. Mental health did not affect prevalence of metabolic syndrome. Conclusion: It is necessary to improve maintain a healthy lifestyle to lower the risk of metabolic syndrome. It is necessary to establish effective dental hygiene customized education and an efficient health management system at the national level that can induce improvement of oral health behavior for the prevention and management of metabolic syndrome.