• 제목/요약/키워드: Synthetic method

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합성식용색소의 정량분석법에 관한 검토 (Studies on the Determination of Synthetic Food Colors)

  • 엄애선;이헌옥;심재영;신동화;김용석;이영환;방정호;신재욱;이달수;홍기형;박성관;최장덕;김희연
    • 한국식품위생안전성학회지
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    • 제20권2호
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    • pp.73-76
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    • 2005
  • 국내에 유통되는 식용 타르색소 9종 및 그 알루미늄레이크 6종의 색소 함량을 한국, 일본, 미국 및 JECFA의 색소정량법에 따라 비교$\cdot$검토하였다. 색소정량법은 한국과 일본이 삼염화티탄에 의한 적정법, 미국은 KiPP generator를 이용한 삼염화티탄법과 spectrophotomete법의 평균값을 구하여 나타냈고, JECFA는 미국방법 중 삼염화티탄법을 사용하였다. 또한 색소의 종류에 따라 함량에 대한 규격기준이 달랐으며 분석 시료의 색소물질 함량은 $85.08-96.40\%$, 식용색소레이크의 함량은 $10.00-36.86\%$로서 모두 규격기준에 적합한 것으로 나타났다.

연속수정법을 이용한 레이더 자료와 지상 강우자료의 합성 (Synthesis of Radar Measurements and Ground Measurements using the Successive Correction Method(SCM))

  • 김경준;최정호;유철상
    • 한국수자원학회논문집
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    • 제41권7호
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    • pp.681-692
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    • 2008
  • 본 연구에서는 자료동화 기법의 가장 간단한 방법이라 할 수 있는 연속수정법(successive correction method)을 이용한 레이더 강우자료와 지상 강우자료의 합성방법에 대한 적용성을 검토하였다. 우선 연속수정법의 적용 시 고려해야 할 사항인 반복계산 횟수 및 영향 반경의 규모를 민감도 분석을 통해 결정하였다. 또한 자료 합성에 대한 정량적인 평가를 위해 밀도 있는 지상 강우자료를 공간분포시켜 실제 강우장을 가정하였다. 최근 자료 합성에 많이 이용되고 있는 co-Kriging을 이용하여 두 자료를 합성하여 연속수정법에 의한 자료 합성 결과를 정량적으로 분석하였다. 그 결과 간단하고 경제적인 자료동화 기법인 연속수정법으로도 co-Kriging을 이용하는 경우의 통계적 특성 및 정확도를 확보할 수 있다는 것을 알 수 있었다.

Algorithm for Predicting Functionally Equivalent Proteins from BLAST and HMMER Searches

  • Yu, Dong Su;Lee, Dae-Hee;Kim, Seong Keun;Lee, Choong Hoon;Song, Ju Yeon;Kong, Eun Bae;Kim, Jihyun F.
    • Journal of Microbiology and Biotechnology
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    • 제22권8호
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    • pp.1054-1058
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    • 2012
  • In order to predict biologically significant attributes such as function from protein sequences, searching against large databases for homologous proteins is a common practice. In particular, BLAST and HMMER are widely used in a variety of biological fields. However, sequence-homologous proteins determined by BLAST and proteins having the same domains predicted by HMMER are not always functionally equivalent, even though their sequences are aligning with high similarity. Thus, accurate assignment of functionally equivalent proteins from aligned sequences remains a challenge in bioinformatics. We have developed the FEP-BH algorithm to predict functionally equivalent proteins from protein-protein pairs identified by BLAST and from protein-domain pairs predicted by HMMER. When examined against domain classes of the Pfam-A seed database, FEP-BH showed 71.53% accuracy, whereas BLAST and HMMER were 57.72% and 36.62%, respectively. We expect that the FEP-BH algorithm will be effective in predicting functionally equivalent proteins from BLAST and HMMER outputs and will also suit biologists who want to search out functionally equivalent proteins from among sequence-homologous proteins.

Displacements, damage measures and response spectra obtained from a synthetic accelerogram processed by causal and acausal Butterworth filters

  • Gundes Bakir, Pelin;Richard, J. Vaccaro
    • Structural Engineering and Mechanics
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    • 제23권4호
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    • pp.409-430
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    • 2006
  • The aim of this study is to investigate the reliability of strong motion records processed by causal and acausal Butterworth filters in comparison to the results obtained from a synthetic accelerogram. For this purpose, the fault parallel component of the Bolu record of the Duzce earthquake is modeled with a sum of exponentially damped sinusoidal components. Noise-free velocities and displacements are then obtained by analytically integrating the synthetic acceleration model. The analytical velocity and displacement signals are used as a standard with which to judge the validity of the signals obtained by filtering with causal and acausal filters and numerically integrating the acceleration model. The results show that the acausal filters are clearly preferable to the causal filters due to the fact that the response spectra obtained from the acausal filters match the spectra obtained from the simulated accelerogram better than that obtained by causal filters. The response spectra are independent from the order of the filters and from the method of integration (whether analytical integration after a spline fit to the synthetic accelerogram or the trapezoidal rule). The response spectra are sensitive to the chosen corner frequency of both the causal and the acausal filters and also to the inclusion of the pads. Accurate prediction of the static residual displacement (SRD) is very important for structures traversing faults in the near-fault regions. The greatest adverse effect of the high pass filters is their removal of the SRD. However, the noise-free displacements obtained by double integrating the synthetic accelerogram analytically preserve the SRD. It is thus apparent that conventional high pass filters should not be used for processing near-fault strong-motion records although they can be reliably used for far-fault records if applied acausally. The ground motion parameters such as ARIAS intensity, HUSID plots, Housner spectral intensity and the duration of strong-motion are found to be insensitive to the causality of filters.

실시간 비주기 태스크 스케줄링을 위한 개선된 합성 이용율에 관한 연구 (A Study on Improved Synthetic Utilization for Real-Time Aperiodic Tasks Scheduling)

  • 문석환;김인국
    • 디지털콘텐츠학회 논문지
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    • 제9권3호
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    • pp.441-448
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    • 2008
  • 최근 비주기 태스크들의 스케줄링 분석을 위한 많은 알고리즘이 제시되었는데, 그중 임의의 시점에 비주기 태스크들의 스케줄링 가능성을 판단하기위한 알고리즘으로서 합성 이용율(synthetic utilization)이 Abdelzaher등에 의해 제시되었는데, 이들은 임의의 시점에 합성이용율의 상한 값인 $\frac 1{1+\sqrt{1/2}}{\approx}0.59$를 넘지 않으면 비주기 태스크들이 스케줄링 가능 하다는 것을 증명 하였다. 하지만 이 방법은 비주기 태스크들의 프로세서 이용율 계산 시 태스크가 실제 모든 실행시간을 종료하여 더 이상의 실행시간을 갖지 않더라도 현재요청집합(current invocation)에 속해 있다면 실행시간과 종료시한을 합성 이용율에 포함하기 때문에 실제 스케줄링 가능한 태스크들이 실행 불가능한 경우로 판단되는 문제점을 가지고 있다. 본 논문에서는 이러한 문제점을 해결하여 더 많은 비주기 태스크들이 스케줄링 가능 하도록 개선된 합성 이용율 방법을 제시하였다.

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Facile Synthesis of 5-Hydroxy-3-pyrrolin-2-ones from Morita-Baylis-Hillman Adducts

  • Lim, Cheol-Hee;Kim, Sung-Hwan;Kim, Jae-Nyoung
    • Bulletin of the Korean Chemical Society
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    • 제33권5호
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    • pp.1622-1626
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    • 2012
  • An efficient synthetic method of various 5-hydroxy-3-pyrrolin-2-one derivatives has been developed starting from the MBH adducts. In addition, some synthetic applicability of the prepared 5-hydroxy-3-pyrrolin-2-ones was demonstrated including the synthesis of lactam-fused tetrahydroisoquinolines.

Ampicillin과 Lysinomethylene Ampicillin의 혈중농도비교(血中濃度比較) (Comparision of the Blood Concentration of Ampicillin and Lysinomethylene Ampicillin in Man)

  • 김종갑;김영일;김봉희
    • Journal of Pharmaceutical Investigation
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    • 제10권3호
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    • pp.1-4
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    • 1980
  • In order to increase the solubility and antibacterial activity of ampicillin, the lysinomethylene ampicillin trihydrate was synthesized. The blood concentrations of ampicillin trihydrate and synthetic lysinomethylene ampicillin trihydrate were determined in 10 healthy male volunteers by using large plate method with Sarcina lutea ATCC 9341. The mean blood concentration of synthetic lysinomethylene ampicillin trihydrate was higher ca. 1.3 times than that of ampicillin trihydrate in 10 test subjects after oral administration.

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2중주파 합성시험회로의 TRV 패턴 분류 및 파라미터 계산 방법 (TRV Pattern Classification and Parameter Calculation Method for Double-Frequency Synthetic Test Circuit)

  • 이용한
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2004년도 하계학술대회 논문집 A
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    • pp.587-589
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    • 2004
  • In this paper analytical pattern classification of TRV waves created by double-frequency synthetic test circuit was proposed. According to the classified patterns of the TRV wave, calculation methods of 3 reference lines and 4 parameters characterizing the TRV wave wire proposed. These methods can be utilized to optimize test facility and to standardize test quality.

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A Novel Synthetic Route to 11-Deoxyanthracycline AB Synthons

  • Kim, Hee-doo;Park, Sang-Ae;Jew, Sang-Sup
    • Archives of Pharmacal Research
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    • 제17권4호
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    • pp.249-255
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    • 1994
  • An efficient synthetic method for 11-deoxyanthracycline AB synthons is described. A verstile key intemediate vinyl bromide 3 was prepared from 5- methodxy-1-tetralone in three steps, and then was converted to the allylic alcohols 4 and 8 which, in tum, fumished highly fuctionalized AB synthons 7 and 12, respectively, via sequential epoxidation-reduction-protection processes.

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Efficient Synthesis of Nucleoside Phosphonates using Olefin Cross-Metathesis

  • Quan, Ling-Lin;Kim, Ai-Hong;Kooh, Dae-Ho;Ko, Ok-Hyun;Hong, Joon-Hee
    • 대한약학회:학술대회논문집
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    • 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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    • pp.173.3-173.3
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    • 2003
  • In recent years, olefin cross-metathesis (CM) has emerged as a powerful and convenient synthetic technique in organic chemistry; however, as a general synthetic method, CM has been limited by the lack of predictability in product selectivity and stereoselectivity. A number of excellent studies have recently appeared in the literature which have shown that with the correct catalyst and reaction conditions CM can be used to access a variety of di-and trisubstituted olefinic products in moderate to high yield with good E/Z ratios. (omitted)

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