• Clinical and Experimental Reproductive Medicine
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• v.48 no.4
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• pp.311-315
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• 2021

Objective: As clinicians and patients await consensus on intraovarian platelet-rich plasma (PRP) treatment, this project evaluated contemporary research trends in the literature. Methods: A PubMed/NLM search aggregated all ovarian PRP-related publications (n=54) to evaluate their scope, abstract utility, submission-to-publication interval, journal selected, article processing charge (APC), free reader access to full-text manuscripts, number and nationality of authors, and inclusion of international collaborators. The NIH Clinical Trials database was also audited. Results: Published output on intraovarian PRP has increased consistently since 2016, especially among investigators in Greece, Iran, USA, and Turkey. Between 2013 and 2021, 42 articles met the relevancy criteria, of which 40.5% reported clinical studies, small series, or case reports, 33% described experimental animal models, and 23.8% were opinion/review papers. Only two works included a placebo control group. The submission-to-publication interval (mean±standard deviation) was 130±96 days, there were 5.9±3.2 authors per project, and journals invoiced US $1,613±1,466 (range, $0-$3,860) for APCs. Conclusion: There was no correlation between APC and time to publish (Pearson's r=-0.01). Abstract content was inconsistent; sample size and patient age were often missing, yet free full-text "open access" was available for most publications (59.5%). The NIH Clinical Trials portal lists eight registered studies on "ovarian rejuvenation," of which two are actively recruiting patients, while four have been terminated or have an uncertain status. Two studies have concluded, with results from one posted to the NIH website. PRP and its derivatives for ovarian treatment show early promise, but require further investigation. Research is accelerating and should be encouraged, particularly placebo-controlled randomized clinical trials.

• The Korean Journal of Archival Studies
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• no.49
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• pp.51-75
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• 2016

A records management agency assessment must reflect the possibility of actual situations including conditions and implementation. Institutional evaluation systems and indicators tools to improve records management. However, the reality is difficult if they are not conducted through the resources and efforts of the organization. The 2017 evaluation system of the National Archives of Korea and the index, which was published in March 2016, are expected to be highly difficult to perform as the frontline field tasks of the institution for a year. It is composed of indices with questionable effectiveness that are difficult to implement on the field. Some of these include the following: three training sessions for more than 10% of all employees, submission of document archive pictures of all schools, submission of the index items of all documents, increasing the utilization level of the standard record management system for the electronic documents that have not been transferred for several years, the transfer of non-electronic documents of all institutions, reclassification of non-disclosed records, etc. It recognizes the fundamental problems of the records management system and the 2017 evaluation indicators that the National Archives has mentioned about operations. As such, now is the time to reflect the years of experience in the field to amass knowledge that will help improve records management.

• Korean Journal of Clinical Pharmacy
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• v.31 no.1
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• pp.53-60
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• 2021

Objective: To gather the opinions of hands-on workers for successful introduction of the Development Safety Update Report (DSUR) according to a five-year comprehensive plan for clinical trial development [Ministry of Food and Drug Safety, 2019]. Methods: We conducted a survey on considerations that industry stakeholders may have related to the enforcement of the DSUR. A questionnaire was distributed among pharmacovigilance specialists from 13 pharmaceutical companies in South Korea on June 4, 2020. The questionnaire comprised two sections: 1) current status of the Drug Safety Data Management System and 2) considerations on the implementation and management of the DSUR. Results: All respondents have agreed the introduction of DSUR is inevitable for regulatory harmonization and safety of trial subject. However, most respondents (85%) felt concern about additional workload with DSUR implementation. They answered that format and operation system of DSUR should be harmonized with those of international standards and authorities need to minimize double burden due to related report. Conclusion: All respondents asserted that domestic DSUR should be harmonized with International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH) E2F guidelines. Respondents from global companies also suggested regulatory authorities allow DSUR written in English to replace Korean version considering their deadline for submission. Moreover, every respondent agreed regulatory authorities need delicate effort when implementing mandatory submission of DSUR to ensure that even small pharmaceutical companies with no experience in DSUR can comply with the system.

• Journal of Animal Reproduction and Biotechnology
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• v.36 no.4
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• pp.230-238
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• 2021

This study attempted to determine the characteristic features of postpartum dairy cows during their return to estrus. Moreover, it investigated the effects of abnormal ovarian cycles (AOC) on subsequent reproductive performance and the relationship between normal ovarian cycles (NOC) and the blood urea nitrogen (BUN) level postpartum. Incidentally, 56.3% of the Holstein cows and 66.7% of the Jersey cows had NOC, whereas the 43.7% and 33.3% of the Holstein and Jersey, respectively, had AOC. Within 100 days of calving, the cows with AOC had significantly lower rates of artificial insemination (AI) submission as well as pregnancy and a significantly longer interval to first AI, as compared to that in the cows with NOC. Additionally, the cows with NOC had a significantly higher first AI conception rate than that in the cows with AOC. In this study, of the 32 Holstein cows, 8 resumed their ovarian cycle within 20 days of calving, 10 resumed the cycle with 21-40 days of calving, 8 within 41-60 days of calving, while the remaining 6 did not resume their ovarian cycles until 60 days postpartum. Furthermore, the likelihood ratios of incidence of NOC are 0.93, 1.94, and 0.38, respectively, in the groups with BUN levels < 15, 15-19.9, and ≥ 20 mg/dl. In conclusion, AOC postpartum adversely affects reproductive performance such as AI submission rate, pregnancy rate, interval to first AI and first AI conception rate; moreover, an increase or decrease in the BUN levels beyond 15-19.9 mg/dL leads to the AOC postpartum.

• Journal of Industrial Convergence
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• v.20 no.7
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• pp.57-64
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• 2022

There are various structures in the underground space, and the structures is managed as 3D data in Integrated Underground Geospatial Map Management System(IUGMMS). The worker transmits and updates the integrated map including the changed underground geospatial data to IUGMMS with the completed book submission program. However, there is a problem in that the transmission time and the update time is delayed because the size of the integrated map file is large. In this paper, we try to extract and transmit only the changed integrated map by obtaining and comparing each spatial characteristic information of the integrated map. As a result of the experiment, the transmission time of the suggestion method is short and the update time is also short than the transitional method because the suggestion method transmits only the integrated map including the changed underground geospatial data. As a result, it was possible to reduce the delay time in transmitting and updating the changed integrated map.

• Aerospace Engineering and Technology
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• v.7 no.2
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• pp.38-45
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• 2008

It is challenging to build the integrated information system for a large scale cooperative R & D project. To develop the aircraft program which especially has several leading agencies and is supported by many demestic/foreign participating companies, the common data flow in harmony is the core factor to achieve a development goal. For this, the development are carried out maintaining the existing management systems of agencies and companies. As a first step, the standard for the common data information and the classification category of technical data are defined. Second, the work flow standards are also set. Based on the foundation, the efficient technical data management system are built including the function of storage, inquiry, revision, link, approval, submission, etc.

• Korean Journal of Mathematics
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• v.18 no.4
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• pp.409-424
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• 2010

We observed the symptoms that occur to students who dislike mathematics when they study mathematics and the data that mathematics is related to foreign language. This study investigated the relation between mathematics and foreign language. Continuous immersion aids not only in acquiring language but also in learning mathematics. For continuous immersion, it is essential to organize small class. We organized small class and compared large class with small class about how the relation between mathematics and language appears in achievement, rate of presence, rate of submission of report, and attitude and enthusiasm. Based on the result, we try to find out the way to increase understanding mathematics and level up the achievements.

• Proceedings of the Korean Information Science Society Conference
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• 2000.10c
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• pp.79-81
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• 2000

최근의 이동 컴퓨팅 환경에서는 정보를 다양한 이동 컴퓨터의 환경에 맞추어서 제공하기 위하여 이동 호스트와 서버사이에 프락시를 넣는 구조가 제안되었다. 프락시는 서버에서 이동 호스트로 전송되는 데이터를 중간에서 이동 호스트의 자원에 알맞게 필터링한 후 이동 호스트로 보내주는 역할을 한다. 이러한 필터링 작업을 보다 효율적으로 하기 위해서는 프락시가 이동 호스트 자원 정보를 알고 있어야 하고 프락시는 이 자원 정보를 관리하며 필요에 맞게 사용할 수 있어야 한다. 본 논문에서는 다양한 이동 호스트들을 효과적으로 지원하기 위하여 필터링에서 고려할 수 있는 자원들의 정보를 분류하고 이 정보를 이동 호스트에서 프락시로 전달하는 방법을 제안한다. 또한 전송된 이동 호스트 자원정보에 따른 프라시 필터링 방법을 제안하였다.

• Clinical and Experimental Pediatrics
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• v.52 no.7
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• pp.756-765
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• 2009

This paper aims to provide an introduction to junior authors on how to write a medical paper in a clearer and more scientific manner. One important thing to be always remembered is that the reviewer and the reader will be reading your paper for the first time, and thus, you should make it as lucid as possible. You should pay attention to consistency in every regard in your paper. Use of the active voice usually makes the sentences shorter and clearer in meaning. Organize your content carefully and present it logically, avoiding unnecessary repetition in different sections. Give a diligent thought to every aspect; research is a work of the mind, not of the hands. Write technically, using powerful language. Most importantly, fulfill the exact submission requirements of the journal.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.13 no.2
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• pp.117-127
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• 2010

This paper aims to give beginners an introductory course on how to write a medical paper more effectively. Bear in mind the reviewer and the reader will be reading your paper for the first time, so you should write it easily. Everything in your paper must be coherent. Use of the active voice is usually shorter and clearer. Organize your story carefully and logically, and then you can avoid unnecessary repetition in different sections. Think hard, because research is made by the mind, not by the hands. Write technically and powerfully. Above all, you have to meet the submission regulation of the target journal exactly.