• Journal of the Korean Magnetic Resonance Society
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• v.19 no.2
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• pp.74-82
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• 2015

Ryanodine receptor (RyR) is one of the two major $Ca^{2+}$ channels in membranes of intracellular $Ca^{2+}$ stores and is found in sarcoplasmic reticulum (SR), endoplasmic reticulum (ER). RyR1 is also the major calmodulin-binding protein of sarcoplasmic reticulum membranes. Residues 4064-4210 in the RyR1 polypeptide chain has similar primary sequence with calmodulin (CaM) and was designated as CaM-like domain (CaMLD). When expressed as a recombinant peptide, CaMLD showed several CaM-like properties in previous studies. Still, previous studies of CaMLD were focused on protein-protein interactions rather than its own properties. Here, we studied the expression of CaMLD and its sub-domains corresponding to each lobe of CaM in Escherichia coli. CaMLD could be obtained only as inclusion body, and it was refolded using urea solubilization followed by dialysis. Using spectroscopic approaches, such as NMR, circular dichroism, and gel filtration experiment, we found that the refolded CaMLD exists as nonspecific aggregate, even though it has alpha helical secondary structure. In comparison, the first half of CaMLD (R4061-4141) could be obtained as natively soluble protein with thioredoxin fusion. After the removal of the fusion tag, it exhibited folded and helical properties as shown by NMR and circular dichroism experiments. Its oligomeric status was different from CaMLD, existing as dimeric form in solution. However, the second half of the protein could not be obtained as soluble protein regardless of fusion tag. Based on these results, we believe that CaMLD, although similar to CaM in sequence, has quite different physicochemical properties and that the second half of the protein renders it the aggregative properties.

• Korean Journal of Pharmacognosy
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• v.37 no.2 s.145
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• pp.67-73
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• 2006

The butanol extracts of Agrimonia pilosa (BAP) induced dose-dependent vascular relaxation of phenylephrine-precontracted aorta, which was abolished by removal of functional endothelium. Pretreatment of the endothelium-intact aortic tissues with $N^G$-nitro-L-arginine methyl ester (L-NAME) and 1H-[1,2,4]-oxadiazole-[$4,3-{\alpha}$]-quinoxalin-1-one(ODQ) inhibited the relaxation induced by BAP. BAP-induced vascular relaxation was also markedly attenuated by addition of verapamiI, while the relaxant effect of BAP was not blocked by indomethacine, glibenclamide, tetraethylammonium (TEA), atropine, or propranolo. In addition, incubation of endothelium-intact aortic rings with BAP increased the vascular production of cGMP. These results suggest that BAP relaxes vascular smooth muscle via endothelium-dependent nitric oxide/cGMP signaling pathway, which may be causally related with L-type $Ca^{2+}$ channels.

• Journal of Satellite, Information and Communications
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• v.1 no.2
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• pp.63-70
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• 2006

This paper presents the results of Ka band qualification model multiplexers for COMS Payload to be launched in 2008. These are the input and output multiplexers of the satellite transponder to use available frequency resources effectively and the diplexer of the satellite antenna to use the same reflector for both transmitting and receiving frequency bands, respectively. The input multiplexer with four frequency channels has four(4) independent channel filters which consist of an 8-pole elliptic band-pass filter for high frequency selectivity and a 2-pole equalizer for group delay equalization. For low insertion loss, mass and volume reduction, manifold type os employed for output multiplexer. E-plane T-junction is used for either splitting or combining a frequency band into two sub-bands. Asymmetric inductive irises are used to tune the receiving filter easily. The electrical performance and environmental test such as vibration test, mechanical shock test, thermal vacuum test and EMC test are performed and the results of all qualification model multiplexers are compliant to the requirement of each multiplexer. Followed by this qualification, the flight model equipment will be developed.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.5 no.11
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• pp.1959-1975
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• 2011

Adaptive Bit Loading (ABL) in Multiple-Input Multiple-Output Orthogonal Frequency-Division Multiplexing (MIMO-OFDM) is often used to achieve the desired Bit Error Rate (BER) performance in wireless systems. In this paper, we discuss some of the bit loading algorithms, compare them in terms of the BER performance, and present an effective and concise Adaptive Grouped Loading (AGL) algorithm. Furthermore, we propose a "weight factor" for loading algorithm to converge rapidly to the final solution for various data rate with variable Signal to Noise Ratio (SNR) gaps. In particular, we consider the bit loading in near optimal Singular Value Decomposition (SVD) based MIMO-OFDM system. While using SVD based system, the system requires perfect Channel State Information (CSI) of channel transfer function at the transmitter. This scenario of SVD based system is taken as an ideal case for the comparison of loading algorithms and to show the actual enhancement achievable by our AGL algorithm. Irrespective of the CSI requirement imposed by the mode of the system itself, ABL demands high level of feedback. Grouped Loading (GL) would reduce the feedback requirement depending upon the group size. However, this also leads to considerable degradation in BER performance. In our AGL algorithm, groups are formed with a number of consecutive sub-channels belonging to the same transmit antenna, with individual gains satisfying predefined criteria. Simulation results show that the proposed "weight factor" leads a loading algorithm to rapid convergence for various data rates with variable SNR gap values and AGL requires much lesser CSI compared to GL for the same BER performance.

• The Journal of the Korea Contents Association
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• v.11 no.12
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• pp.241-249
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• 2011

This study takes a uses and gratification theory based approach to identifying the relation between TV home-shopping channel use motivation and purchase intention. The results are summarized as follows. First, in respect of TV home-shopping channel use motivation, the analysis results reveal three factors: convenience, information seeking, and entertainment. Among these, the factor of convenience was the first in the order of importance. Secondly, 1)It is found that use motivation also has some limited influence on purchase intention. 2)Selectivity and involvement degree, the sub-categories of audience activity, are found to be the variables with the highest prediction ability, suggesting a need to give a particular attention to them. 3)In addition, viewing amount, a variable of use behavior, is shown to have a significant influence on purchase intention. The followings are the implications of the study results. First, marketing strategies that enable maximization of shopping convenience are required. Second, there is a need to approach the delivery of TV home-shopping contents as a kind of broadcasting contents on their own rather than merely a medium for selling goods.

• Journal of the Korea Computer Industry Society
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• v.5 no.5
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• pp.761-770
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• 2004

The multicarrier direct sequence code-division (MC-DS/CDMA) is a well-known multiple access and data transmission scheme that is applicable for various mobile and wireless communications. Particularly for modern, smart vehicles equipped with multiple sensors, MC-DS/CDMA is one of the possible means for giving the sensors to get connected one another for sending and receiving messages and control information. For intra-vehicalur communicaiton and networking applications, we have proposed a novel MC-DS/CDMA multiple access and data transmission scheme incorporating a new idea of inserting sub-symbol based cyclic prefixes for compromising inter-symbol interference. In the performance investigation of our MC-DS/CDMA, we have looked into system performances related to bandwidth utiltzation, coding gain, and multiple number of sensors. Since the channel delay is comparatively shorter inside of vehicle than any other general mobile channels, the proposed scheme can be a successful candidate for networking wireless sensors simultaneously operting in an intelligent vehicle.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2005.11a
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• pp.346-350
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• 2005

Effects of the changes of a film cooling mass flow rate and operating conditions on the heat flux characteristics of the subscale calorimeter were studied. A film cooling ring with twelve orifices is inserted between the injector head and the calorimeter. The calorimeter is composed of nineteen cooling channels. When a mass flow rate of film cooling is 10.5 % of a main fuel mass flow rate, maximum heat flux at the nozzle throat is decreased by 30% compared to that without film cooling. In the OD3(of-design point) test result, maximum heat flux at the nozzle throat is increased by 31% compared to that of the DP(design point) test when a film cooling flow rate is zero.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.39C no.5
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• pp.435-446
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• 2014

Even if it is important to transmit high rate multimedia information without any transmission errors for surveillance systems, it is difficult to achieve error-free transmission due to infra-less adhoc networks. In order to reduce the transmission errors furthermore, additional signal overheads or retransmission of signals should be required, but they may lead to transmission delay. This paper represents a study on low delay and adaptive video transmission for the unmanned surveillance systems by developing system protocols. In addition, we introduce an efficient and adaptive control algorithm using system parameters for exploiting unmanned surveillance system properly over multi-channels.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.17 no.6
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• pp.89-95
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• 2017

UFMC is known as a candidate for the 5G wireless communication system because it is robust against ICI and better performs in asynchronous situation than OFDM. In the UFMC system, the filtering is performed for each subband so the performance of the filter is very important. The Dolph-Chebyshev filter has been used in conventional UFMC system because of its small out-of-band radiation. However it has distortion in the sub-band and skirt characteristics is not good enough. Therefore, it is necessary to study a new type of UFMC filter which reduces the distortion in the subband and has sharp skirt characteristics. In this paper we analyze the effect of filter frequency response in UFMC system and suggest the wavelet based type of filter that substitutes the Dolph-ChebyShev filter used in the conventional UFMC system. The simulation results show that wavelet filter has better BER performance in multipath fading channels than conventional filters.

• Journal of the Institute of Electronics Engineers of Korea TE
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• v.39 no.4
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• pp.395-402
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• 2002

In the conventional public switched telephone network(PSTN), there are various types of modulation that can be used in ADSL to offer fast data communication, two of which are CAP(Carrierless Amplitude Phase) and DMT(Discrete MultiTone). As we consider the current situation, DMT is getting more predominant in the market than CAP. One of the reasons is that it gives high performance in spite of its high complexity Since DMT divides the full range of bandwidth into 256 sub-channels, it can be highly adaptive in the circumstances, where the problems of attenuation and noise caused by the propagation distance are very crucial. In this paper, a new bit loading algorithm for DMT modulation is proposed. The proposed algorithm can be efficiently implemented in a way that it requires less computation than the conventional modulation techniques. In contrast to the conventional algorithms which perform sorting processing, the proposed algorithm uses look-up tables to reduce the repetition of calculation. Consequently, it is shown that less processing time and lower complexity can be achieved.