• Title/Summary/Keyword: Structure determination

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Preparation and Determination of Structure of L-3-Deoxymimosine-containing Peptides

  • Chae, Whi-Gun;Lee, Eung-Seok
    • Archives of Pharmacal Research
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    • 제23권3호
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    • pp.211-221
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    • 2000
  • L-3-Deoxymimosine-containing decapeptides were prepared for the development of protein tyrosine kinase (PTK) inhibitors. During the preparation of peptides, several side products were formed. identification and determination of major peptides generated were reported.

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대리문제가 자본구조에 미치는 효과에 관한 연구 (A Study on the Effect of Agency Problems in the Determination of Capital Structure)

  • 김형준;황동섭
    • 산업경영시스템학회지
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    • 제18권36호
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    • pp.365-370
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    • 1995
  • In recent years, there have been attempts to explain firms' capital structure based upon the agency theory which considers agency problems arising due to ownership structure. Agency theory starts from the coctractual relationship (explicit or implicit) between principals and agents. Since uncertainty exists in real world and information is distributed asymmetrically, there are conflicts between principals and agents. The objectives of this study are to analyze, based upon agency theory, factors which are expected to affect firms' capital structure and to test empirically the relevance of agency cost hypothesis about the determination of capital structure, For these purposes, this paper carried out multiple regression in order to examine whether the factors of agency costs affect significantly the determination of capital structure. The results of empirical analysis are summarrized as follows; First, insider-equity ration has been negatively correlated with capital structure. Second, growth opportunity variabless has been insignificant coefficients with capital structure.

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다층 케이블 돔형 구조물의 자기평형을 위한 부재력 비율 결정 (Determination of Member Force Ratios for Self-equilibrium State of Multi-Layered Cable Dome Type Structures)

  • 김재열
    • 한국공간구조학회논문집
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    • 제13권2호
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    • pp.75-82
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    • 2013
  • For each cable component in a cable dome structure, pre-tension is needed for stability of whole the structure. The summation of these pre-tension at each joint should be zero to achieve the self equilibrium structure. The first step in cable dome structure analysis is to find the ratio of pre-tension in each member which can produce a stable and structure on self-equilibrium. In this paper, a new method based on the basic principle of closed force polygon for equilibrium system is proposed for the determination of self-equilibrium mode of cable dome structure. A single layer cable dome and two multi layer type domes have been analyzed. The ratios of cable members are determined by the presented method, and check the validation of the results by numerical calculation.

Covariance Analysis Study for KOMPSAT Attitude Determination System

  • Rhee, Seung-Wu
    • International Journal of Aeronautical and Space Sciences
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    • 제1권1호
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    • pp.70-80
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    • 2000
  • The attitude knowledge error model is formulated for specifically KOMPSAT attitude determination system using the Lefferts/Markley/Shuster method, and the attitude determination(AD) error analysis is performed so as to investgate the on-board attitude determination capability of KOrea Multi-Purpose SATellite(KOMPSAT) using the covariance analysis method. Analysis results show there is almost no initial value effect on Attitude Determination (AD) error and the sensor noise effects on AD error are drastically decreased as is predicted because of the inherent characteristic of Kalman filter structure. However, it shows that the earth radiance effect of IR-sensor(earth sensor) and the bias effects of both IR-sensor and fine sun sensor are the dominant factors degrading AD error and gyro rate bias estimate error in AD system. Analysis results show that the attitude determination errors of roll, pitch and yaw axes are 0.056, 0.092 and 0.093 degrees, respectively. These numbers are smaller than the required values for the normal mission of KOMPSAT. Also, the selected on-orbit data of KOMPSAT is presented to demonstrate the designed AD system.

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장력안정화 트러스의 단위구조 형상결정에 관한 연구 (A Study on the Shape-Determination for the Unit-structure of Truss Stabilized by the Cable Tension)

  • 권택진;한상을;최옥훈
    • 한국전산구조공학회:학술대회논문집
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    • 한국전산구조공학회 1997년도 봄 학술발표회 논문집
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    • pp.152-159
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    • 1997
  • This unit - structure of truss stabilized by cable tension is composed of four truss member adding to a central post and eight cables, and is connected by hinge joints and is stabilized by cable tension. As this unit - structures itself is a statically closed and stabilize system individually, it can be employed to assemble a structure with a variety of configuration. In this paper, for determination the shape of the unit - structure of truss stabilized by the cable, characteristics such as the stabilized range of the various geometrical parameter about unit system and the relation of the best governing paramter is demonstrated, and the relation of the results is compared in the range for the stabilization of unit-structure.

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모듈을 고려한 조립군의 교체성 평가 (Evaluation of Ease of Exchange of Subassembly Considering Module)

  • 목학수;양태일;곽동영
    • 한국정밀공학회지
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    • 제17권7호
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    • pp.170-180
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    • 2000
  • In this paper, to evaluate ease of exchange of subassembly considering module, it needs to analyze structure and function of subassembly, assembly and disassembly process. Exchange process of module can be divided into pre-process and in-process, and determination factors of exchange process are defined by analyzing characteristics of assembly and disassembly process. Based on the analysis of characteristics for structure and function of subassembly, influential factors of module can be proposed. Considered the interrelationship between determination factors of ease of exchange and influencing factors of module, ease of exchange can be evaluated.

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설계빈도변화를 고려한 천변저류지 최적위치 선정 (Determination of Optimal Location of Washlands Considering Design Frequency)

  • 백천우;안태진
    • 한국수자원학회논문집
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    • 제42권7호
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    • pp.559-569
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    • 2009
  • 환경 및 경제적 문제 등으로 인해 댐과 같은 대규모 수공구조물의 신설이 점차 어려워짐에 따라, 천변저류지 등과 같은 소규모 수공구조물의 설치가 대안으로 검토되고 있다. 천변저류지와 같은 소규모 수공구조물의 경우 홍수량, 유입수문곡선, 천변저류지 용량 및 월류위어의 월류고 등에 따라 홍수저감효과가 민감하게 반응하므로, 대상 저류지의 제원 결정을 위해 목표하는 설계빈도 결정이 선행되어야 한다. 또한 천변저류지를 이용하여 목표하는 홍수저감효과를 얻기 위해 다수의 천변저류지가 설치되어야 하며, 즉 천변저류지군의 홍수조절효과는 이들 저류지군을 연계한 수문네트워크의 분석에 의해 산정되어야 한다. 본 연구에서는 설계빈도 변화에 따른 천변저류지군의 홍수저감효과를 산정해 보았으며 산정된 홍수저감효과를 분석하여 천변저류지의 최적위치를 선정하기 위한 새로운 지수를 제안하였다. 천변저류지의 최적위치를 결정하기 위해 개발된 기존의 의사결정모형을 보완하여 제안된 지수를 산정하기 위한 모형을 개발하였으며, 개발된 모형을 안성천유역에 적용하여 기존의 연구결과와 비교하고, 적용성을 검토하였다. 그 결과 천변저류지 최적위치를 결정하기 위한 기준으로의 활용이 가능한 것으로 판단되었다.

Miniaturized Rectangular Slotted Nameplate Antenna Design for Satellite and Radio Determination Applications

  • Shanmuganantham, Thangavelu;Kaushal, Deepanshu
    • ETRI Journal
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    • 제39권6호
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    • pp.813-819
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    • 2017
  • A slotted rectangular nameplate antenna design with a patch bearing the name of the first author is presented. A $6.8mm{\times}26mm{\times}1.6mm$ substrate of FR-4 epoxy material having a relative permittivity of 4.4 and a dielectric loss tangent of 0.02 is used. Additionally, the feeding technique used is a coaxial mechanism. The standard antenna design parameters, including the reflection coefficient, bandwidth, radiation pattern, gain, directivity, and voltage standing wave radio (VSWR) for the proposed prototype are analyzed using a high-frequency structure simulator (HFSS) v-15, and are compared to the measured results. The designed structure may be considered for different satellite- and radio-determination applications at the respective resonant frequencies.

Computational Approaches for Structural and Functional Genomics

  • Brenner, Steven-E.
    • 한국생물정보학회:학술대회논문집
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    • 한국생물정보시스템생물학회 2000년도 International Symposium on Bioinformatics
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    • pp.17-20
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    • 2000
  • Structural genomics aims to provide a good experimental structure or computational model of every tractable protein in a complete genome. Underlying this goal is the immense value of protein structure, especially in permitting recognition of distant evolutionary relationships for proteins whose sequence analysis has failed to find any significant homolog. A considerable fraction of the genes in all sequenced genomes have no known function, and structure determination provides a direct means of revealing homology that may be used to infer their putative molecular function. The solved structures will be similarly useful for elucidating the biochemical or biophysical role of proteins that have been previously ascribed only phenotypic functions. More generally, knowledge of an increasingly complete repertoire of protein structures will aid structure prediction methods, improve understanding of protein structure, and ultimately lend insight into molecular interactions and pathways. We use computational methods to select families whose structures cannot be predicted and which are likely to be amenable to experimental characterization. Methods to be employed included modern sequence analysis and clustering algorithms. A critical component is consultation of the presage database for structural genomics, which records the community's experimental work underway and computational predictions. The protein families are ranked according to several criteria including taxonomic diversity and known functional information. Individual proteins, often homologs from hyperthermophiles, are selected from these families as targets for structure determination. The solved structures are examined for structural similarity to other proteins of known structure. Homologous proteins in sequence databases are computationally modeled, to provide a resource of protein structure models complementing the experimentally solved protein structures.

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