• Journal of Animal Science and Technology
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• v.52 no.6
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• pp.475-480
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• 2010

The bovine fatty acid binding protein 4 (FABP4) plays an important role to uptake intracellular fatty acid. It has been previously reported as a positional candidate gene for marbling score in livestock. The re-sequencing of FABP4 gene detected a polymorphic AT repeated sequence in intron II of FABP4 gene. Allelic distribution for this microsatellite marker was examined in other cattle breeds. A total of 8 alleles were detected with diverse repeat units (14 to 21 AT repeat) in Hanwoo and 7 breeds. Of the 8 alleles, the predominant alleles were $[AT]_{16}$, $[AT]_{18}$ and $[AT]_{19}$ in the Hanwoo and 7 cattle breeds. The linear mixed model for genotypic effect (3237AT) on carcass traits showed a significant effect on marbling score (MAR P=0.025) and live weight (LWT; P=0.04) in the 583 Hanwoo cattle population. Live weight (LW) was highest in the homozygous $(AT)_{17}$ genotype ($557.5{\pm}6.94$) and lowest in the heterozygous $(AT)_{16/17}$ genotype ($521.7{\pm}7.70$). On the other hand, the homozygous $(AT)_{17}$ genotype ($3.0{\pm}0.15$) has the highest effect on marbling score and the lowest effect was in homozygous (AT)$_{18}$ genotype ($2.2{\pm}0.15$). The marbling score difference between both groups was 0.8 which is around two times higher than SNP genotype effect on marbling score in Limousin $\times$ Wagyu crosses.

• Informatization Policy
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• v.24 no.3
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• pp.91-107
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• 2017

Digital forensics is the process of uncovering and interpreting electronic data and materials found in digital device in relation to crime. The goal of the process is to preserve any evidence in its most original form which shall be having the force of law. The digital forensic market is increasing with a growth of ICT in domestic and global market. Many countries including U.S. are actively performing researched regarding a structured investigation by collecting, identifying and validating the digital information for the purpose of reconstructing past events which so does in academic society in Korea. This paper is to understand overall research trend about digital forensics and derive future strategy by integrating the result of meta-analysis into practices based on five criteria - main theme and topic, analysis phase, technical method for analysis, author's affiliation, and unit of analysis and method. 239 papers are analyzed, which were selected out of 470 papers published for 10 years (2007~2016) in academic journal on the list of KCI (Korea Citation index). The results of this analysis will be used to examine the characteristics of research in the field of digital forensics. The result of this research will contribute to understanding of the research trend and characteristics leading the technology-driven academia, through which measures for further research development and facilitation are suggested.

• Korean Journal of Plant Resources
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• v.13 no.3
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• pp.243-248
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• 2000

This study was conducted to evaluate the effects of weed control and lodging reduction in the cultivation of buckwheat. The effect of weed control was significant. In the herbicide plot, nevertheless, grain yield and plant height were more decreased than habitual and vinyl mulching plots. Therefore, the application of herbicide was considered unnecessary in buckwheat cultivation having short growth period. In the habitual plot, dominant weed species are Digitaria sanguinalis, Erigeron annuus, E. canadensis, Setaria viridis, and Stellaria alsine var. undulata. On the effect of plant dwarf agent, C.C.C. and TIBA, plant height became shorter than habitual plot but the grain yield decreased. The latter tip pinching time, the less in grain yield which indicate tip pinching is ineffective in grain yield and lodging reduction. Among the wild species and cultivars of Fagopyrum, F. urophyllum was differentiated into xylem and phloem tissues indicating woody plant. Stem hardness of this species was the hardest as 625,110,000 dyne/cm$^2$which is at least 3.5 times harder than F. esculentum cv. Suwon #12. Therefore, it needs that the woody habitat gene of F. urophyllum is transfered into other cultivars in buckwheat breeding strategy.

• Ecology and Resilient Infrastructure
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• v.7 no.4
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• pp.374-387
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• 2020

This study was conducted to provide basic data for monitoring the trend of ecosystem change and establishing management plans for wetland protection areas by understanding the status of naturalized plants. In 21 wetland protection areas, 129 taxa, including 10 invasive alien species, were recorded. The naturalized plants appeared mostly as 71 taxa in the Chimsil wetland and were not observed in the Moojechineup and Sumeunmulbaengdui wetlands. Among the naturalized plants, 42 taxa (32.6%) originated from North America. Annual and biennial plants accounted for 68.2% (88 taxa). The frequencies of occurrence of naturalized plants growing in dry secondary grasses such as Erigeron annuus and Trifolium repens were high, and clonal plants that propagated by making stolons and struck roots accounted for 19.4% (25 taxa). The naturalized and urbanization indices showed positive correlations with location factors such as wetland, agricultural land, and used area. However, a negative correlation was found between altitude and forest. Therefore, a management plan that synthetically considers the occurrence frequency and growth characteristics of naturalized plants as well as the locational characteristics of wetland protection areas is required.

• Journal of Korean Neurosurgical Society
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• v.65 no.6
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• pp.790-800
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• 2022

Objective : EID3 (EP300-interacting inhibitor of differentiation) was identified as a novel member of EID family and plays a pivotal role in colorectal cancer development. However, its role in glioma remained elusive. In current study, we identified EID3 as a novel oncogenic molecule in human glioma and is critical for glioma cell survival, proliferation and invasion. Methods : A total of five patients with glioma were recruited in present study and fresh glioma samples were removed from patients. Four weeks old male non-obese diabetic severe combined immune deficiency (NOD/SCID) mice were used as transplant recipient models. The subcutaneous tumor size was calculated and recorded every week with vernier caliper. EID3 and AMP-activated protein kinase α1 (AMPKα1) expression levels were confirmed by real-time polymerase chain reaction and Western blot assays. Colony formation assays were performed to evaluate cell proliferation. Methyl thiazolyl tetrazolium (MTT) assays were performed for cell viability assessment. Trypan blue staining approach was applied for cell death assessment. Cell Apoptosis DNA ELISA Detection Kit was used for apoptosis assessment. Results : EID3 was preferentially expressed in glioma tissues/cells, while undetectable in astrocytes, neuronal cells, or normal brain tissues. EID3 knocking down significantly hindered glioma cell proliferation and invasion, as well as induced reduction of cell viability, apoptosis and cell death. EID3 knocking down also greatly inhibited tumor growth in SCID mice. Knocking down of AMPKα1 could effectively rescue glioma cells from apoptosis and cell death caused by EID3 absence, indicating that AMPKα1 acted as a key downstream regulator of EID3 and mediated suppression effects caused by EID3 knocking down inhibition. These findings were confirmed in glioma cells generated patient-derived xenograft models. AMPKα1 protein levels were affected by MG132 treatment in glioma, which suggested EID3 might down regulate AMPKα1 through protein degradation. Conclusion : Collectively, our study demonstrated that EID3 promoted glioma cell proliferation and survival by inhibiting AMPKα1 expression. Targeting EID3 might represent a promising strategy for treating glioma.

• Knowledge Management Research
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• v.25 no.3
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• pp.279-299
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• 2024

The socio-cultural and economic activities of users in virtual worlds are increasing, and virtual consumption of purchasing virtual products is expanding. The future growth potential of this virtual consumption market is very high and has the potential to change the existing traditional consumption ecosystem. This study was interested in the phenomenon of virtual consumption in the most rapidly growing gaming virtual world, and based on the consumption values theory and the concept of self-improvement, major factors promoting virtual consumption in the gaming virtual world were derived. Then, the influence of factors on intention to continue virtual consumption was verified. In particular, this study compared and analyzed whether the influence of factors varies depending on demographic groups (age group and gender) and types of virtual products mainly consumed. This study collected data from users who actually experienced virtual consumption in the game virtual world and empirically analyzed the influence of factors promoting virtual consumption and differences by group. Accordingly, it provides implications for knowledge management in terms of establishing a service development strategy in response to the virtual consumption phenomenon in virtual worlds, which will expand further in the future, and revitalizing the convergence economic ecosystem between the virtual and reality economy.

• Journal of Korea Technology Innovation Society
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• v.21 no.1
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• pp.236-264
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• 2018

This study investigates the trend of the patent applications and the future direction of ICT in Gyeongbuk Province by employing patent portfolio analysis, one of the methodology of map analyses for industry-related ICT issues. Thus, this study aims to investigate the ICT development trend based on ICT patent information in Gyeongbuk Province. The promising technologies in ICT industry are extracted by applying patent portfolio analysis, one of the patent map analyses. The analysis results can be applied to the establishment of research and development strategies. This study extracts ICT trend by applying International Patent Classification to the patents registered in Gyeongbuk. For promising technologies, this study analyzed the patents based on the ICT Classification Code. Based on the analysis results, this study presents the trend of patent application, technology share, patent activity status, the trend of patent application by each technology according to ICT classification, the growth stages of ICT market, registration parties for patents, joint researches of research parties, and primary parties of patent applications. After drawing promising technologies, this study provides the future progress direction of ICT industry in Gyeongbuk Province. The research results also can be applied to securing technology competence and developing strategy of technology policy.

• Journal of Korean Society of Environmental Engineers
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• v.28 no.1
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• pp.81-87
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• 2006

The industrial systems contain many sites and components susceptible to biofilms formation. Biofilms play an important role in microbial growth and industrial fouling. Thus, the control of the biofilms in industrial systems has been emphasized, however, the efficient controlling method was not provided yet. Since silver compounds have no residual and corrosion problem, the interest for silver compounds as a biofilm control disinfectant has been increased. In this study, we attempted to examine the disinfection ability of silver compounds. The disinfection efficiency of two silver compounds(silver ion and silver oxide) were evaluated for biofilms in comparison with suspended cells using well known indicator microorganisms(E. coli, P. aeruginosa) and compared with that of chlorine. Silver compounds were found to be effective in inactivating E. coli and P. aeruginosa biofilms. The reason for superiority of silver compounds as biofilm disinfectant was suggested by that silver can penetrate into the inner biofilm matrix faster than chlorine without consumption. This study reports that the disinfectant which is highly effective in inactivating the suspended cells in water becomes the less effective for controlling biofilm because of its high reactivity. This results imply that the effective strategy for biofilm control can be achieved by considering thoroughly the chemical nature of disinfects and biofilm structure and the reactivity between them.

• Journal of Distribution Science
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• v.11 no.6
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• pp.31-40
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• 2013

Purpose - The Northeast Asian Logistic Hub strategy was established to create a national competitive advantage in northeast Asia. Countries in this region are competing fiercely to become the central base distribution port as the volume of container shipping continues to increase due to the northeast Asian (especially Chinese) economic growth. The primary method by which shippers are improving their customer service and distribution is enhancing profits by minimizing call ports on the key route through strategic affiliations and the use of large vessels. Each nation is planning large-scale investments in the construction of sea ports that can accommodate large vessels. This paper proposes ways by which the logistical strategies of domestic corporations can keep pace with changes in government policy concerning the Northeast Asian Business Hub policy. It examines the logistics system in the Northeast Asian region, analyzes the government's Northeast Asian Business Hub policy, and suggests logistical strategies for domestic corporations through an analysis based on a questionnaire designed to grasp domestic firms' needs and goals. Research design, data and methodology - The purpose of this study is to determine how shipping companies establish partnerships with third-party logistics providers and draws out the implications of the results. The survey methods used were personal interviews and questionnaires distributed to a sample population through e-mail, fax, mail, and telephone. A total of 600 questionnaires were distributed, of which 165 were returned. Among these, ten were excluded due to insufficient content; ultimately, 155 were used for the sample. The statistical data collection process was analyzed through data coating and a statistical package program. Results - This study argues that greater flexibility in policies, administration, and systems will be needed to significantly improve established business practices. In this dissertation, we primarily identify that in order to become a center of northeast Asian logistics, Korea must adopt a new paradigm and abandon the existing systems that are based on the economic and social systems that have stemmed from bureaucracy, inflexibility, chauvinism, and equalitarianism. Flexible policies, administration, and systems will be necessary to improve business practices. Domestic corporations must establish a strategic logistics hub and related network while simultaneously pursuing value-added logistics businesses by increasing their manpower and building a logistics information system. This will strengthen their competitive edge and lead to system improvements. Conclusions - Domestic corporations must adopt a new paradigm and use more reasonable business laws, systems, and policies that are based on market-driven flexibility and transparency. Moreover, social norms and regulations should be established to help ensure political and social security. Korea must also develop a culture of tolerance for foreign companies. Finally, the paradigm defining the policy governing the development of the capital city and its satellite cities in this context must be changed.

• The KIPS Transactions:PartD
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• v.12D no.3 s.99
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• pp.461-470
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• 2005

This paper suggests a new policy for consolidating a company's profits by segregating the clients using the contents service and allocating the media server's resources distinctively by clusters using the cluster analysis method of CRM, which is mainly applied to marketing. In this case, CRM refers to the strategy of consolidating a company's profits by efficiently managing the clients, providing them with a more effective, personalized service, and managing the resources more effectively. For the realization of a new service policy, this paper analyzes the level of contribution $vis-\acute{a}-vis$ the clients' service pattern (total number of visits to the homepage, service type, service usage period, total payment, average service period, service charge per homepage visit) and profits through the cluster analysis of clients' data applying the K-Means Method. Clients were grouped into 4 clusters according to the contribution level in terms of profits. Likewise, the CRFA (Client Request Filtering algorithm) was suggested per cluster to allocate media server resources. CRFA issues approval within the resource limit of the cluster where the client belongs. In addition, to evaluate the efficiency of CRFA within the Client/Server environment the acceptance rate per class was determined, and an evaluation experiment on network traffic was conducted before and after applying CRFA. The results of the experiments showed that the application of CRFA led to the decrease in network expenses and growth of the acceptance rate of clients belonging to the cluster as well as the significant increase in the profits of the company.