• JSTS:Journal of Semiconductor Technology and Science
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• v.13 no.1
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• pp.79-86
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• 2013

We describe a neural stimulator front-end with arbitrary stimulation waveform generator and adaptive supply regulator (ASR) for visual prosthesis. Each pixel circuit generates arbitrary current waveform with 5 bit programmable amplitude. The ASR provides the internal supply voltage regulated to the minimum required voltage for stimulation. The prototype is implemented in $0.35{\mu}m$ CMOS with HV option and occupies $2.94mm^2$ including I/Os.

• Journal of the korean academy of Pediatric Dentistry
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• v.6 no.1
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• pp.27-33
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• 1979

The author studied the response to the stimulation of an electric pulp stimulator of healthy 854 permanent anterior teeth in 122 children aged from six to eleven years old, during different stages of tooth development. The results were as followings: 1) In completely open apices, 13.1% (18 teeth) showed positive responses, and 86.9% (120 teeth) showed negative responses. In two-thirds open apices 33.1% (75 teeth) showed positive responses, and 66.9% (152 teeth) showed negative responses. In one-third open apices 57.8% (118 teeth) showed positive responses, and 42.2% (86 teeth) showed negative responses. In closed apices 80.0% (228 teeth) showed positive responses, and 20.0% (57 teeth) showed negative responses. 2) The number of positive responses increased in each upper and lower central incisors during the stages of root development, but not in upper lateral incisors. 3) There were no significant differences statistically in responses between the teeth of the right and left sides and the upper and the lower jaw, in the same stages of root development.

• The Korean Journal of Pain
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• v.33 no.2
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• pp.97-98
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• 2020

• Preventive Nutrition and Food Science
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• v.17 no.1
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• pp.83-86
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• 2012

To support beneficial effects of makgeolli for human health, we investigated for the presence of 1,4-dihydroxy-2-naphthoic acid (DHNA), a bifidogenic growth stimulator (BGS), from commercial makgeolli products. Among eleven makgeolli products (A~K), four showed positive peaks for DHNA in high performance liquid chromatography analysis. Makgeolli product A in particular contained the highest concentration of DHNA (0.44 ppm), as confirmed by liquid chromatography-mass spectrometry. Furthermore, BGS activity of the makgeolli product A was higher than those of products in which DHNA was not detected. These results indicate that makgeolli can be a good source for DHNA and that DHNA-enriched makgeolli could be developed by modifying manufacturing procedures and controlling its microbiota.

• Proceedings of the KIPE Conference
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• 2000.07a
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• pp.628-631
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• 2000

A new control method for precision robust speed control of a PMSM(Permanent Magnet Synchronous Motor) using load torque observer is presented. With this system we can obtain more reliable eye moving singal(nystagmus) Until now rotating chair system which is called 2D-optokinetic stimulator is used to make dizzincess. However an inclined rotating chair system witch is 3D-optokinetic stimulator is needed to obtain the precise dizziness data. This 3D-optokinetic sitimulator include unbalanced load aused by unbalanced center of mass. For this case new compensation method is considered to obtain robust speed control using load torque observer. To reduce the effect of this disturbance we can use dead-beat observer which has high gain. The application of the load torque observer is published in [1] for position control. A problem of using speed information such as amplifying effect of noise is reduce by moving average process. The experimental results are depicted in this paper to show the effect of this proposed algorithm.

• JSTS:Journal of Semiconductor Technology and Science
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• v.17 no.1
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• pp.120-128
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• 2017

This paper describes a neural stimulation system that employs an inductive coupling link to transfer power and data wirelessly. For the reliable data and power delivery, a self-referenced amplitude-shift keying (ASK) demodulator and a wide-range voltage regulator are suggested and implemented in the proposed stimulator system. The prototype fabricated in 0.35 um BCD process successfully transferred 1.2 Kbps data bi-directionally while supplying 4.5 mW power to internal MCU and stimulation block.

• Preventive Nutrition and Food Science
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• v.16 no.4
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• pp.386-389
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• 2011

Previous studies have confirmed that fermented whey produced by Leuconostoc mesenteroides CJNU 0147 or Lactobacillus casei CJNU 0588 display bifidogenic growth stimulator (BGS) activity. The present study sought to determine if the strain itself can improve the growth of bifidobacteria in co-cultures. In reinforced clostridial medium (RCM), both strains stimulated the growth of a Bifidobacterium lactis strain during the exponential phase and also stimulated the growth during almost all growth phases in whey broth. Fermented whey containing viable Leu. mesenteroides CJNU 0147 and L. casei CJNU 0588 cells maintained viability of the B. lactis strain stored at $10^{\circ}C$ in MRS broth. Viable cell count of the B. lactis strain without the fermented whey was decreased to 5.6 log cfu/mL after 15 days, whereas that of the strain with the fermented whey was slightly increased to 7.1 log cfu/mL as compared with initial viable cell count of 6.9 log cfu/mL.

• The Journal of the Korean Society for Microbiology
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• v.16 no.1
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• pp.65-70
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• 1981

A microculture technique for the mixed lymphocyte culture test(MLC) in the sheep is described. The optimal incubation periods for the MLC are varied from 4 to 6 days depending on the sources of lymphocytes. It is found that a 2.5:1 stimulator-responder cell ratio and the responder cell concentration of $1{\times}10^5$ cells/well produce the highest($^3H$)-thymidine incorporation. Moreover cryopreservation of bovine lymphocytes results in satisfactory and reproducible MLC reaction. It is also evident that the MLC reactions of the sheep are under the control of histocompatibility matching between the stimulator cells and the responder cells. Significance of the technique as a too! for study on cell mediated immunity in sheep system, either normal or squamous cell carcinoma-bearing, are discussed.

• Journal of Biomedical Engineering Research
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• v.11 no.2
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• pp.257-268
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• 1990

A system has been developed for monitoring the effect of neuromuscular blocking frugs and the neuromuscular function during anesthesia and surgery. This system is composed of software and hardware, the latter are nerve stimulator, force transducer, interface board(preamplifier, filter, peripheral input/output) and personal computer (apple ll) , the former are programmed in ASSEMBLY and BASIC language. The nerve stimulator which is controlled by personal computer is capable of delivering single shocks at o.)Hz, train of four at 2Hz and tetanic stimulation at 30, 100, 200Hz. The response, adduction of the thumb, is sensed by the force transducer. The output of the force transducer Is amplified, filtered, converted digital signal and then processed by the per- sonal computer. The personal computer quantia4es twitch and traln of four tesponse and calculates the 74 ratio (Ta/Tl )between the first and fourth response of train of four. This ratio is used to estimate the level of the neuromuscular block. This system has reaserch potential for determining the effect of newer neuromuscular blocking drugs for comparlsion with presently used drugs of alternatively, for delerminig the effects of blocking drugs in altered physilogical states.

• Journal of Sensor Science and Technology
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• v.20 no.4
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• pp.254-259
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• 2011

In this paper, a current stimulator circuit with adaptive supply regulator for retinal prosthesis is proposed. In current stimulation systems, the stimulating circuits with wide voltage swing range are needed due to the high impedance of the retina cell and microelectrodes. Thus, previous researches adopt the high voltage architecture to obtain the enough operating range. The high voltage architecture, however, could increase the power consumption and can damage the retina cells. The proposed circuit provides the adaptively regulated supply voltage by measuring the difference between desired stimulation current and the actual stimulation current. The proposed circuit can achieve the extended range of the allowable cell impedance, improved accuracy of the stimulation current, and higher biosafety.