• 제목/요약/키워드: Stimulants

검색결과 148건 처리시간 0.024초

인삼(人蔘)의 중추신경계(中樞神經系)에 대(對)한 작용(作用) (Effects of Panax Ginseng on the Central Nervous System)

  • 오진섭;박찬웅;문동연
    • 대한약리학회지
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    • 제5권1호
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    • pp.23-28
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    • 1969
  • Saponin, essential oil and fat oil fractions were fractionated from Panax Ginseng and their potentiating or inhibiting actions during the combined use of several central nervous system stimulants or depressants were observed to elucidate the possible role of Ginseng fractions on the central nervous system. Saponin, essential oil and fat oil fractions shortened nembutal sleeping time at low dosage (10 mg/kg) but contrarily they produced potentiation of nembutal hypnosis at high dosage (50mg/kg). In the toxicity study of amphetamine, saponin and essential oil fractions reduced the toxicity in aggregated mice at high dosage (100 mg/kg) but such decreased lethality was not observed in isolated mice. Ginseng fractions, especially high dose of saponin fraction (100mg/kg) prolonged the survival time after injection of convulsive dose of metrazol or cocaine and saponin fraction also prolonged the onset of cocaine convulsion at high dosage (100 mg/kg).

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시스템 이론 기반의 안전사고 모델의 해석과 응용사례 소개 (An Introduction to Systems Theory Approach to Accident Modeling and Its Applications)

  • 박철호;박영원
    • 시스템엔지니어링학술지
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    • 제1권1호
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    • pp.20-25
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    • 2005
  • This paper presents the general system theory and its applications to the safety analysis method that is a recent trend over the traditional event-driven model. This new model is known as STAMP(Systems Theory Accident Modeling and Process) proposed by Nancy G. Leveson in MIT. The new model has benefits o f systemic approaches concerning the system safety as a whole including the context it is in, its stimulants and outcomes, and its parts as well as the relationships among them in a holistic manner. The method consists of a hierarchical control structure, a process model, and the safety constraints governing the control. This paper demonstrates an example that contrasts the differences between the approaches of STAMP and the traditional safety models.

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Migration of Styrene in Relation to Food-Packaging Materials

  • Seog, Eun -Ju;Lee, Jun-Ho;Rakesh K. Shingh
    • Preventive Nutrition and Food Science
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    • 제4권2호
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    • pp.152-158
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    • 1999
  • Polystyrene is frequently used for food packaging because of its eaxy processing rigidity , and low cost. Styrene, which is present in detectable amouts in the polymer, is usually considered to be the substance responsible for the possible tainting of a polystyrene-packed food by migration. The contamination of foods and beverages by trace amounts of materials which have migrated from plastics use din packaging is a concern both on the grounds of adversely affecting product quality and of food safety. These lead to increasing attention to the potentional hazards of a large variety of plastic materials and foods. In this paper we reviewed the history of Styrene and various analytical methods of sample preparation and detection to assess the extent to which styrene is present in food-grade polystrene materials and to what extent it leaked into foods and food stimulants.

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GINSENG SELF-ADMINISTRATION IN MONKEYS

  • Siegel Ronald K.
    • 고려인삼학회:학술대회논문집
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    • 고려인삼학회 1980년도 학술대회지
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    • pp.223-228
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    • 1980
  • Four monkeys (Macaca mulatta) were allowed to press a lever in their cages in order to earn access to one gram pieces of Panax ginseng root. Self-administration performance on an operant schedule (mult FR20 F11) was characterized by frequent pauses and increased intertrial interval responding. When given 23 hour unlimited access to ginseng root, as well as to food and water, all animals titrated their daily intake to approximately 1.5 g/kg. Gross behavioral changes included increases in vocalization, activity, stereotyped movements, and weight loss. These patterns of behavior are typical of those seen when monkeys self-administer psychomotor stimulants. Further studies on ginseng's reward value can be conducted using this animal model.

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취조직내 Protein Methylases 활성도에 관한 연구 (Studies of the Activities of Protein Methylases in Pancreatic Tissues)

  • 이명연;홍성렬;이춘우
    • 약학회지
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    • 제27권4호
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    • pp.295-301
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    • 1983
  • Among the many protein modifications methylation is being investigated actively with regard to bacterial chemotaxis, gene regulation, muscle contraction, cytochrome c methylation, and the synthesis of the acyl transporter, carnitine. In this study the activities of protein methylase I, II, and III in pancreatic tissues of rat, mouse, and guinea pig were examined. Furthermore, the effect of cholinergic agents on the activity of protein methylases in pancreatic fragment of guinea pig was also examined in order to test the relationship between protein methylation and pancreatic secretion. The results are as follows. 1) The activities of protein methylases were generally high in pancreatic tissues of guinea pig and mouse but low in the tissue of rat. 2) The cholinergic stimulants, acetylcholine and carbachol at a concentration of $10^{-5}M$ decreased the activities of protein methylase I, II, and III compared with unstimulated control. 3) The inhibitory effect of the cholinergic stimulant on the activities of protein methylases was not blocked by atropine at a concentration of $10^{-5}M$.

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각종자극제가 고로슬래그 미분말 혼입 모르타르의 초기재령 압축강도 발현에 미치는 영향 (Effect of Early Compressive Strength Development with Blast Furnace Slag Using Various stimulants Mortar.)

  • 김진형;이한승
    • 한국건축시공학회:학술대회논문집
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    • 한국건축시공학회 2011년도 춘계 학술논문 발표대회 1부
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    • pp.57-58
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    • 2011
  • In the experiment, we add to NaOH, Ca(OH)2 and Calcium Hydroxide as the Slag stimulus also mixed the cement stimulus such as NaSCN, TEA and CaCl2 for improving compressive strenth of concrete which added the Blast Furnace Slag Powder at 1 and 3 days. In the result of strength test, It showed that 2percentage of activator 1 and 5percentage Ca(OH)2, 1percentage of activator 3 and 5percentage of Ca(OH)2 are higher than 100 percentage OPC.

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일부 인문계 고등학교 남학생들의 건강행위에 관한 연구 (A Study on the Health Behavior of High School Students)

  • 김춘미;최정명;현혜진
    • 한국학교보건학회지
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    • 제13권1호
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    • pp.109-115
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    • 2000
  • The Purpose of this study is to analyze the health behavior of high school students and to find factors influencing it. A questionnaire survey was used for collecting data from 201 male students between May 1 and June 30, 1993. The data were analyzed by the multiple regression technique in an SPSS package. The major results are as follows: (1) 84.5% of the students responded to the survey are regularly exercising to promote their health and 44.8% of them are doing something to manage stress. (2) 28.9% of the students are smoking, 43.3% of them are drinking, 5% of them are taking adhesives, 6.5% are taking stimulants, and 4.5% of them are taking analgesics. (3) while self-efficacy of the students and health interests of their parents are positively related to health promoting behaviors, they are negatively related to health risk behaviors.

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알칼리 자극제 NaOH의 첨가율에 따른 고로슬래그 기반 경화체의 강도 특성 (Strength Properties of Blast Furnace Slag-based Hardened Materials with Addition Rate of Alkali Stimulant NaOH)

  • 경석현;최병철;이상수
    • 한국건축시공학회:학술대회논문집
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    • 한국건축시공학회 2019년도 추계 학술논문 발표대회
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    • pp.135-136
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    • 2019
  • Recently, as the interest in environmental issues increases, the construction industry needs to recycle blast furnace slag, circulating fluidized bed Combustion fly ash, etc. to solve industrial by-products, and to develop artificial stone. In this study, the strength characteristics based on blast furnace slag according to the addition rate of alkali stimulant NaOH are investigated. The experimental results showed that the flexural and compressive strengths increased with the addition of alkali stimulants. Based on these results, it will be presented as a basic research data for the manufacture of artificial stone and will be tested later.

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Phospholipases Dl and D2 Regulate Different Phases of Exocytosis in Mast Cells

  • Lee, Jun-Ho;Chang, Sung-Ho;Kim, Young-Mi;Her, Her Erk;Choi, Wahn-Soo
    • 대한약학회:학술대회논문집
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    • 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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    • pp.135.1-135.1
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    • 2003
  • The rat mast cell line RBL-2H3 contains both phospholipase D (PLD)1 and PLD2. Previous studies with this cell line indicated that expressed PLD1 and PLD2 are both strongly activated by stimulants of secretion. We now show by use of PLDs tagged with enhanced green fluorescent protein that PLD1, which is largely associated with secretory granules, redistributes to the plasma membrane in stimulated cells by processes reminiscent of exocytosis and fusion of granules with the plasma membrane. (omitted)

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CBS-dust 치환에 따른 고로슬래그 다량치환 시멘트 벽돌 품질에 미치는 영향 (Effect of CBS-dust replacement rate on the Qualities of High Volume GGBFS Cement Bricks)

  • 한준희;한수환;김수호;윤치환;한민철;한천구
    • 한국건축시공학회:학술대회논문집
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    • 한국건축시공학회 2021년도 가을 학술논문 발표대회
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    • pp.105-106
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    • 2021
  • This study examines the performance of CBS-Dust for the utilization of cement bricks as alkali stimulants for furnace slag replacement binders. It converts the CBS-Dust substitution rate and the excess slag substitution rate. According to the analysis, when replacing CBS-Dust with 65~70 % of BS substitution rate and 7.5~10 % of CBS-Dust, it shows excellent performance as an alkali stimulant of BS' potential hydrophobic reaction, and it is expected to be effective for secondary products of BS replaced in large quantities.

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