• Korean Chemical Engineering Research
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• 제50권2호
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• pp.358-364
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• 2012

철 촉매를 이용한 Fischer-Tropsch 합성 반응과 수성 가스 전환 반응에 대한 반응 메커니즘과 반응 속도식을 5 채널 고정층 반응기를 이용하여 조사하였다. 실험 조건은, 반응물 합성가스 $H_2$/CO 비 0.5~2, 반응물 공급 유량 60~80 ml/min, 반응 온도 $255{\sim}275^{\circ}C$로서 반응 압력은 1.5 MPa을 유지하였다. F-T 합성 반응의 반응 속도식($r_{FT}$)은 반응 속도 결정 단계로서 분자로 흡착된 CO와 기상의 수소 분자와의 반응을 바탕으로 하는 Eley-Rideal 반응 메카니즘을 통해 계산되었고, WGS 반응의 반응 속도식($r_{WGS}$)은 formate 중간체 생성 반응을 반응 속도 결정 단계로 가정하여 결정되었다. 실험 결과, F-T 합성 반응의 반응 속도식과 WGS 반응의 반응 속도식은 각각 탄화수소 생성과 $CO_2$ 생성에 대한 반응 속도 실험값을 잘 모사하였고, 또한 power law에 근거한 CO 전환 반응에 대한 반응 속도식도 실험값과 잘 일치하였다. 이처럼, 각각의 반응 메카니즘을 바탕으로 도출된 반응 속도식($r_{FT}$, $r_{WGS}$, $-r_{CO}$)은 실험값과 여러 가지 기존 문헌에서 보고된 반응 속도식 모델과 잘 일치하였다.

• 한국전자파학회논문지
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• 제16권7호
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• pp.760-767
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• 2005

본 논문에서 우리는 DAML(Dielectric Air-gapped supported Microstrip Line) 구조를 이용하여 새로운 구조의 SIR대역 통과 여파기를 설계 제작하였다. 제작된 SIR대역 통과 여파기는 MIM capacitor를 커플링 포트로써 사용함으로 DAML구조를 이용하여 쉽게 제작될 수 있다. 더욱이 이러한 구조는 CPW interfaces를 가지고 있고 DAML구조의 링 공진기는 기판으로부터 $10{\mu}m$높이로 분리되어 있기 때문에 일반적인 평면 구조의 MMICs와 집적하기 유리하다. 제작된 필터의 측정 결과, 60 GHz에서 $10\%$의 대역폭, 60.7 GHz에서 2.84 dB의 삽입 손실, 56 GHz에서 18.4 dB의 감쇠 특성, 60 GHz에서 23 dB의 반사 특성을 얻었다.

• Computers and Concrete
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• 제19권1호
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• pp.59-68
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• 2017

This study focused on modeling the behavior of the compressive stress using the average strain and ultrasonic test results in concrete. Feed-forward backpropagation artificial neural network (ANN) models were used to compare four types of concrete mixtures with varying water cement ratio (WC), ordinary concrete (ORC) and concrete with short steel fiber-reinforcement (FRC). Sixteen (16) $150mm{\times}150mm{\times}150mm$ concrete cubes were used; each contained eighteen (18) data sets. Ultrasonic test with pitch-catch configuration was conducted at each loading state to record linear and nonlinear test response with multiple step loads. Statistical Spearman's rank correlation was used to reduce the input parameters. Different types of concrete produced similar top five input parameters that had high correlation to compressive stress: average strain (${\varepsilon}$), fundamental harmonic amplitude (A1), $2^{nd}$ harmonic amplitude (A2), $3^{rd}$ harmonic amplitude (A3), and peak to peak amplitude (PPA). Twenty-eight ANN models were trained, validated and tested. A model was chosen for each WC with the highest Pearson correlation coefficient (R) in testing, and the soundness of the behavior for the input parameters in relation to the compressive stress. The ANN model showed increasing WC produced delayed response to stress at initial stages, abruptly responding after 40%. This was due to the presence of more voids for high water cement ratio that activated Contact Acoustic Nonlinearity (CAN) at the latter stage of the loading path. FRC showed slow response to stress than ORC, indicating the resistance of short steel fiber that delayed stress increase against the loading path.

• Journal of Microbiology and Biotechnology
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• 제23권9호
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• pp.1327-1338
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• 2013

The humanized anti-hepatocyte growth factor (HGF) monoclonal antibody (mAb) YYB-101 is a promising therapeutic candidate for treating various cancers. In this study, we developed a bioprocess for large-scale production of YYB-101 and evaluated its therapeutic potential for tumor treatment using a xenograft mouse model. By screening diverse chemically defined basal media formulations and by assessing the effects of various feed supplements and feeding schedules on cell growth and antibody production, we established an optimal medium and feeding method to produce 757 mg/l of YYB-101 in flask cultures, representing a 7.5-fold increase in titer compared with that obtained under non-optimized conditions. The optimal dissolved oxygen concentration for antibody production was 70% $pO_2$. A pH shift from 7.2 to 7.0, rather than controlled pH of either 7.0 or 7.2, resulted in productivity improvement in 5 L and 200 L bioreactors, yielding 737 and 830 mg/ml of YYB-101, respectively. The YYB-101 mAb highly purified by affinity chromatography using a Protein A column and two-step ion exchange chromatography effectively neutralized HGF in a cell-based assay and showed potent tumor suppression activity in a mouse xenograft model established with human glioblastoma cells.

• Korean Chemical Engineering Research
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• 제53권6호
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• pp.695-702
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• 2015

Liquid-liquid extraction (LLE) using various solvents was studied for recovery of acetic acid from a synthetic ethanol fermentation broth. The microbial fermentation of sugars presented in hydrolyzate gives rise to acetic acid as a byproduct. In order to obtain pure ethanol for use as a biofuel, fermentation broth should be subjected to acetic acid removal step and the recovered acetic acid can be put to industrial use. Herein, batch LLE experiments were carried out at $25^{\circ}C$ using a synthetic fermentation broth comprising $20.0g\;l^{-1}$ acetic acid and $5.0g\;l^{-1}$ ethanol. Ethyl acetate (EtOAc), tri-n-octylphosphine oxide (TOPO), tri-n-octylamine (TOA), and tri-n-alkylphosphine oxide (TAPO) were utilized as solvents, and the extraction potential of each solvent was evaluated by varying the organic phase-to-aqueous phase ratios as 0.2, 0.5, 1.0, 2.0, and 4.0. The highest acetic acid extraction yield was achieved with TAPO; however, the lowest ethanol-to-acetic acid extraction ratio was obtained using TOPO. In a single-stage batch extraction, 97.0 % and 92.4 % of acetic acid could be extracted using TAPO and TOPO when the ratio of organic-to-aqueous phases is 4:1 respectively. A higher solvent-to-feed ratio resulted in an increase in the ethanol-to-acetic acid ratio, which decreased both acetic acid purity and acetic acid extraction yield.

• 한국시뮬레이션학회논문지
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• 제23권4호
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• pp.203-210
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• 2014

본 연구는 생산공정운영시 발생하는 담당자의 의사결정 지원을 위한 학습형 공정 의사결정 시스템 구축방법에 대한 것이다. 먼저 추출 및 누적된 각 공정 별 이력 데이터에서, 주요한 주요자원(Critical Resource)을 단계적 회귀법에 따라 선정한다. 선정된 주요자원을 독립변수로 취급하여 담당자의 의사결정 대상이 되는 공정운영 성과를 종속변수로 하는 회귀모형을 산출하고, 해당 주요자원으로 구성된 시뮬레이션 모형을 설계한다. 메타휴리스틱 방법을 통하여 의사결정 시점의 생산계획 및 목적에 대한 시뮬레이션 분석을 실행하고, 복수 대안 및 가능해(기대성과)를 산출한다. 각각의 대안에서 주요자원 별 회귀모형을 구성하는 분석 값을 회귀식에 대입하고, 여기에서 얻어지는 값과 시뮬레이션 분석에 의해 산출된 가능해 간의 비교를 통하여 그 차이가 가장 작은 대안을 최적대안으로 선정하고 실제 공정운영 의사결정에 반영하여 생산을 실시한다. 이때 발생하는 공정 이력 데이터들은 이후 의사결정을 위한 회귀모형에 피드백 된다.

• 한국환경보건학회지
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• 제24권2호
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• pp.9-19
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• 1998

Laboratory experiments were carried out to investigate the performance of anaerobic sequencing batch reactor(ASBR) for digestion of a municipal sludge. Each cycle of the ASBR comprised feeding, two-or three-day reaction, one-day thickening, and withdrawal. The reactors were operated at an HRT of 10days and 5days with an equivalent organic loading rate of 0.8-1.54 gVS/l/d, 1.81-3.56 gVS/l/d at 35$\circ$C, respectively. Solids accumulation was remarkable in the ASBR during start-up period, and directly affected by settleable solids in the feed sludge. Floatation thickening occured in the ASBRs, and Solids profiles at the end of thickening step dramatically changed at solid-liquid interface. Slight difference in solids concentrations was observed within thickened sludge bed. Efficiencies through floatation thickening were comparable to that of additional thickening of the completely mixed control reactor. Average solids concentrations in the ASBRs were 2.2-2.6 times higher than that in the control throughout the total operation period. The dehydrogenase activity had a strong correlation with the solids concentration. Organics removals based on clarified effluent of the ASBRs were consistently above 86%. Remarkable increase in equivalent gas production of 27-52% was observed at the ASBRs compared with the control though the control and ASBRs showed similiar effluent quality. Thus, digestion of a municipal sludge was possible using the ASBR in spite of high concentration of solids in the sludge.

• 한국생활과학회지
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• 제18권3호
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• pp.793-798
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• 2009

Hair cut is one of the best useful technical tool for hair styling. In this study using the rule of the layers of hair design, balanced for visual art, perceptual ability and form created by the principles of analysis and offer hair cuts and hair design of the representation of regions and even hair design as the basis of a student of Hair Beauty and all the people working in the field can create a variety of hair design puts the purpose to establish a basis. The result of this study can be outline as follows: First, the step line and the movement of the relationship between the law of the layers above and below the length of the same layer techniques, the same consists of a vertical cross-section of the overall round shape of the cut same layer is created and the appropriate volume and movement, the movement of low-layer round a little bit more feeling and expression is used when you want. High-layer used to want to move a lot of light and could see that. Second, the layer of the Law and over direction, lifting, section, the line control. weight control and analyzed by principle and the principle of the process of forming the written form was unknown. Third, hair design, the expansion of the expressive power of the law of the layers, and the section of the over direction depends on the presence of line control to express the length of the outline I had to, lifting the weight to adjust form controls, and the expression of Hair Design will be expanding the width. A hair designer, a layer style to create a zone he thought the law of the first layer formative area To further the reach will be a lot of research, leading up formative aspects of this research thesis do not have missing parts, or as a result of the Beauty of Hair Design and the width of a hair design education in the field can perform to help feed the reference materials that will be.

• 한국자동차공학회논문집
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• 제22권2호
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• pp.166-174
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• 2014

Fuel injection pressure has steadily increased in diesel engines for the purpose of improving fuel efficiency and cleaning exhaust gas, but it has now reached a point, where the cost for higher pressure does not warrant additional gains. Common rail systems on modern diesel engines have fuel pumps that are mechanically driven by crankshaft. The pumps actually house two pumping module inside: a low pressure pump component and a high pressure pump component. Part of the fuel compressed by the low pressure component returns to the tank in the process of maintaining the pressure in the common rail. Since the returning fuel represents pumping loss, fuel economy improves if the returned fuel can be eliminated by using a properly controled electrical fuel pump. As the first step in developing an electrical fuel pump the fuel supply system on a 6 liter diesel engine was modeled with AMESim to analyze the workload and the fuel feed rate of the injection pump, and the results served as basis for selecting a suitable servo motor and a reducer to drive the pump. A motor controller was built using a DSP and a program which controls the common rail pressure using a proportional control method based on the target fuel pressure information from the engine ECU. A test rig to evaluate performance of the fuel pump is implemented and used to show that the newly developed electrically driven fuel pump can satisfy the fuel flow demand of the engine under various operating conditions when the rotational speed of the pump is adequately controlled.

• 한국응용과학기술학회지
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• 제27권3호
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• pp.233-239
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• 2010

Supercritical carbondioxide is very effective in removing oils from a variety of seed matrices, devoid of any appreciable amount of phospholipid content. However, the limited solubility of phosphalipids in supercritical carbondioxide leaves behind a potentially valuable by-product in spent seed matrix. Any phospholipid extraction process from the spent matrix must maintain the structure and the quality of phospholipids and must be compatible with the end use of the seed protein meal an animal feed or for human consumption. An initial supercritical carbondioxide extraction of soybean flakes was performed at 32 MPa and $80^{\circ}C$ to extract the oils, leaving the phospholipids in the deflatted soybean flakes, A second step was performed on the defatted soybean flake using $X_{eth}$=0.10, Varying the pressure from 175 MPa to 70.6 MPa and temperature from $60^{\circ}C$ to $80^{\circ}C$. For all supercritical carbon dioxide/ethanol mixture extractions, a fraction rich in phospholipids was obtained. The fractions extracted from defatted soybean flakes were dried and them redissolved in chloroform before HPLC-ELSD analysis. Quantitative and qualitative analysis of phospholipids on soybean seeds, defatted soybean flake, and different extracted phospholipid fractions was carried out, to ascertain the effect of extraction pressure and temperature.