• Nutrition Research and Practice
• /
• v.12 no.5
• /
• pp.378-386
• /
• 2018

BACKGROUND/OBJECTIVES: Benign prostatic hypertrophy (BPH) is a major cause of abnormal overgrowth of the prostate mainly in the elderly. Corni Fructus has been reported to be effective in the prevention and treatment of various diseases because of its strong antioxidant effect, but its efficacy against BPH is not yet known. This study was designed to evaluate the therapeutic efficacy of Corni Fructus water extract (CF) in testosterone-induced BPH rats. MATERIALS/METHODS: To induce BPH, rats were intraperitoneal injected with testosterone propionate (TP). Rats in the treatment group were orally administered with CF with TP injection, and finasteride, which is a selective inhibitor of $5{\alpha}$-reductase type 2, was used as a positive control. RESULTS: Our results showed that the increased prostate weight and histopathological changes in BPH model rats were suppressed by CF treatment. CF, similar to the finasteride-treated group, decreased the levels of testosterone and dihydrotestosterone by TP treatment in the serum, and it also reduced $5{\alpha}$-reductase expression and concentration in prostate tissue and serum, respectively. In addition, CF significantly blocked the expression of the androgen receptor (AR), AR co-activators, and proliferating cell nuclear antigen in BPH rats, and this blocking was associated with a decrease in prostate-specific antigen levels in serum and prostate tissue. CONCLUSIONS: These results suggest that CF may weaken the BPH status through the inactivation of at least $5{\alpha}$-reductase and AR activity and may be useful for the clinical treatment of BPH.

• Journal of Distribution Science
• /
• v.4 no.1
• /
• pp.53-78
• /
• 2006

We call this world network society. Logistics is one of important network systems which connect people, materials and information. The World Economy Conditions of 21st Century has been Changed so rapidly. These Changes are more conspicuous in Northeast Asia than other Regions. China, North Korea and Russia have reformed their Economical and Social Systems, which enlarged the Trade Volume and Traffic Demand in this Area and between Europe. The Railway System Crossing the Eurasia Continent, such as TSR(Trans Siberian Railway), TCR(Trans China Railway), TMR(Trans Manchuria Railway), TMGR(Trans Mongolia Railway) and TKR(Trans Korea Railway), have been becoming very important to enhance the International Transportation efficiency and to connect each continents by International Railways. This Paper investigated and surveyed the logistical Environments surrounding this Korea Peninsula. And concerned with the Crossing Continents Railway, TSR,TCR(TMR, TMGR), TKR, operating Conditions and Tasks that must be considered and solved were also investigated. Especially the Current Logistical Conditions of China, Russia, and North Korea and their Problems were surveyed. And the SWOT of these Railways were analyzed and compared. The Visions and Goals of these Inter-Continental Railways were suggested in terms of their Rationalization of Operations and efficient Connections among many Countries. Not only the Policies and Strategies/Tactics which should be considered but also and Many detail countermeasures which should be introduced and adopted were suggested.

• Journal of Korean Society for Atmospheric Environment
• /
• v.25 no.1
• /
• pp.26-37
• /
• 2009

Recently rapid environmental changes due to desertification and industrialization in China make a threat to Korea, especially during Asian Dust Event (ADE). This study was aimed to compare symptoms and behaviors related to ADE between Korea and China. We conducted questionnaires on self-reported symptoms and behaviors before and during ADE. Korean and Chinese subjects were grouped into children, adults, and elderly by nation (n=791). Statistical analyses were performed by $X^2$-test, Fisher's exact test, t-test and chow's test for comparing differences between Korean and Chinese. We estimated the odds ratio for perceived symptoms during ADE by preventive behavior, using Generalized Estimation Equation (GEE). The study indicated that there were significant differences between symptoms in Korea and those in China such as cold, cough, and sore throat, especially in elderly. Preventive behaviors such as avoiding outdoor activity and wearing sunglasses were more often performed in China than Korea. However wearing mask was more often performed in Korea than China. After adjusting for age, sex, educational level, and smoking status, the odds ratio (OR) of dry cough symptom in Korea was significantly decreased by closing the windows and wearing a mask during ADE. In China, the OR of dry cough symptom was decreased by wearing a mask and avoiding outdoor activity. We found that China which had higher performance of preventive behavior showed lower prevalence of symptoms during ADE than Korea. Also preventive behaviors could affects prevalence of symptoms during ADE. This results suggest that preventive behavior. could reduce symptoms during ADE and there are needed for. more attentions to reduce a threat of ADE.

• Journal of Korean Neurosurgical Society
• /
• v.60 no.6
• /
• pp.691-700
• /
• 2017

Objective : The authors prospectively analyzed the effect of one-level or two-level anterior cervical discectomy and fusion (ACDF), comparing stand-alone cages and cage-with-plate fixation constructs with respect to clinical outcomes and radiologic changes. Methods : A total of 84 patients who underwent one-level (n=52) or two-level ACDF (n=32) for cervical disc disease and who completed 2 years of follow-up were included in this study. The patients were divided by cervical level and grouped into ACDF-Cage-only and ACDF-Cage-with-plate groups. The following parameters were assessed using radiographs : subsidence, C2-C7 lordosis angle, fusion segment angle, adjacent disc space narrowing, and fusion status. Clinical outcomes were assessed using the neck disability index (NDI) and visual analog scale scores for arm pain. Results : In the comparison of one-level ACDF-cage-only and ACDF-cage-with-plate groups, the NDI score was better in the cage-only group at the 3-, 12-, and 24-month follow-ups : however, no significant difference in clinical outcomes was observed. In the comparison of two-level ACDF-cage-only and ACDF-cage-with-plate groups, no difference in any clinical outcome was observed between the two groups. At the 24-month follow-up, subsidence was observed in 45.8% of patients in the one-level cage-only group and 32.1% of patients in the one-level cage-with-plate fixation group. There was no statistically significant difference in the incidence rate between the two groups (p=0.312). Subsidence in the two-level cage-only group (66.6%) was significantly more frequent than in the two-level cage-with-plate fixation group (30%; p=0.049). The fusion rate for patients in the one-level cage-only group was not significantly different from that in the one-level cage-with-plate fixation group (cage-only, 87.5%; cage-with-plate fixation, 92.9%; p=0.425) ; fusion rate in the two-level patients were also similar between groups (cage-only, 83.3%; cage-with-plate fixation, 95%; p=0.31). Conclusion : Our clinical results showed that for single-level cases, plate fixation had no additional benefit versus cage-only; for two-level ACDF cases, the fusion rate and clinical outcomes were similar, although the cage-with-plate fixation group had a lower incidence of cage subsidence than did the cage-only group. We conclude that physicians should be aware of this possible disadvantage associated with using cervical plates in one-level ACDF. However, in two-level ACDF, subsidence is more likely to occur without plate fixation, and thus the addition of plate fixation should be considered.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.17 no.12
• /
• pp.26-33
• /
• 2016

The cost of preparing munitions in weapon system operation and management has been rapidly increasing and current weapon systems have become complicated and diverse due to new warfare pattern changes and the rapid growth of advanced scientific technology. Moreover, as a part of the execution plans of creative economics, the Korean government is actively reviewing how to minimize the costs of preparing munitions. Accordingly, this study derived the issues of munitions management for decreasing munitions preparing costs. First, the issues of munitions management were introduced through review and analysis with respect to the munitions classification criteria, regulations and systems, and equipment maintenance information systems. Second, we proposed the application and necessity for the real-name system which is responsible for munitions management and the fragmentation of the maintenance instructions status classification criteria.. Also, we were analyzed that the effects depending on the application. Finally, we proposed that the linkage system which is currently military active with equipment maintenance information systems as well as the total life-cycle management system (TLCSM) improvements to the itemized data and records management system by utilizing IT technology CMB that must be done in order to improve the issues.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.17 no.12
• /
• pp.218-225
• /
• 2016

Recently, Korea has undergone rapid social and economic development, and with that came various changes in living habits and disease patterns; the nation, accordingly, has been alerted to the associated risks of chronic ailments. As risk factors of metabolic syndrome commonly include causal factors of chronic diseases, prevention is important. The prevalence of metabolic syndrome in Korean adults is 22.4%, which comprises a large portion of the whole disease (Korean National Health and Nutrition Examination Survey, 2013). This study aims to examine the elements of healthy living practices by analyzing the risk factors of metabolic syndrome and health behaviors, and provide basic materials to contribute to the activation of health promotion. Among 12,481 subjects of the source data from the 2014 community health survey, which was performed on adults aged 19 and over in Jeonlabuk-do, 12,185 people were analyzed in this study using SPSS 23.0. There were significant differences with respect to sex, smoking status, age, education level, and number of days of physical activity among the results of the difference of the risk factors of the metabolic syndrome according to the characteristics of the health behavior of the subjects. Of the risk factors for metabolic syndrome, this study emphasized the necessity of strategies to promote health programs regarding the management of drinking, smoking, physical activities, depression, subjective health condition and quality of life to the group of those with dyslipidemia, hypertension, and diabetes.

• Journal of Korean Society of Rural Planning
• /
• v.20 no.3
• /
• pp.191-199
• /
• 2014

The current rural conditions are undergoing the change from the past production-intensive structure to an integral and complex one of producing, processing, selling, touring and lodging owing to the changes of life-style, consumption trend and social environments. The rural area is developing into a community of rural tourism villages to grow into one management system along with the assistance of the government's various supporting projects. Through this, the rural designing has got to play a significant role as one of the factors of the enhancement of competitiveness and the increase of income. Therefore, those previous studies on the variety and possibility of rural development are being employed for the researches which are to develop techniques of branding, marketing and packaging. In particular, the researches for VI (Village Identity), BI (Brand Identity) and designs of landscaping, packaging of agricultural specialties and display stores, which definitely shows that the importance of rural designing, is being paid a lot more attention to. Thus, this study has verified the site commercialization and its effect by developing some practical designing with the focus of package design at rural tourism villages. The Okgye Village in Yoncheon was selected for study subject based on the result of status investigation. This study has analyzed such problems as lack of village identity, non-description of items and their indispensible marks which were seen their designs of village and packaging. The colors of major items and the village image being substituted into the image scale of IRI color were estimated so that the appropriate colors might be selected, along with which the shapes of major items were decided to be motif for the village symbol and design to be created. The designs of such major items as grains, greens and sauces were created with the consideration of the easiness of loading, the continuity of using and the aesthetics. For grains, those outer boxes which are possible for set-packaging and small-sized packaging have been developed. For greens were developed the boxes with the structure of the permeability for the persisten't quality as well as the possibility for packaging small amount. In case of sauces, those outer-boxes equipped with fixing tray were made with the transport-convenience taken into consideration. The sticker-label designs for all those three were also developed which stand for the village identity and are conveniently used in each farm family. When this development was applied at the sites, it was found that the satisfaction and reliability of consumers as well as the satisfaction of farmers were raised along with the increase by more than 30% after the improvement.

• Korean Security Journal
• /
• no.62
• /
• pp.113-134
• /
• 2020

This study was conducted to examine the influence of the psychological health of the released offenders on their adaptation to community. Researchers analyzed the survey data of 216 participants who received joint marriage support from the Korea Legal Protection and Welfare Corporation. The results showed that the education level, marriage status, and monthly income were having a positive influence on the community adaptation of the released offenders, and the higher the depression and inter-personality among the risk factors of psychological health, the more negative the community adaptation. A higher sense of self-esteem, a psychological health protection factor, has a positive effect on community adaptation while reducing the influence of risk factors, depression and inter-personality. In sum, high self-esteem can contribute to increasing social life satisfaction after release from prison, promote risk factors to positive life changes, suppress negative situations and increase the possibility of successful community adaptation. Although this study confirmed that self-esteem is the most important factor among psychological factors for successful community adaptation of inmates, it will require relevant follow-up research and multi-disciplinary support because psychological factors alone cannot solve the problem.

• Proceedings of the Korea Society for Simulation Conference
• /
• 2001.10a
• /
• pp.170-202
• /
• 2001

Simulation is used to reduce a risk involved in the new project and decision-making in an organization and to save cost and time by forecasting different situations. The objectives of this research are to acknowledge the need of simulation through the real life sample and to encourage the use of the simulation method in the future consulting project by continuously making the necessary improvements. This research analyzed the effectiveness of the simulation based on the sample use of simulation method in 1994 and 1997 for the BPR project of certification issuance process at the Supreme Court. In order to evaluate the value of the proposed simulation model, we examined the gap, which existed between the simulation result and the operational data collected by visiting the actual sites where AROS (Automated Registry Office System: automation system developed by LG-EDS Systems) is being utilized. We also identified the causes for the existing gap. According to the analysis result, (1) the gap came from the status change of thinking that the concentration of certification issuance request has eased after the computerization, (2) the gap existed in the operational process because they failed to consider the situational factors of each registry office in the simulation model, and (3) lastly the gap came from the difficulty of formulating the mathematical model for predicting the complex and diverse behavior pattern of individuals requesting the certification issuance. In order to narrow the existing gaps, we made a proposal to improve the certification issuance process where software of certification issuance vending machine was upgraded in order to help the people to use the service conveniently, more part time workers were hared when there was a overload of certification issuance request, and the quality of the certification Issuance vending machine is improved, In this research, we examined an efficient way of resource allocation based on the simulation conducted in 1994 and 1997. By reflecting changes since the simulation of 1994 and allocating the clerk and machine based on the predicted results of the simulation, we maximized the efficiency of the certification issuance process. In conclusion, this research examined the future usability of simulation method based on the analysis result and identified the key issues to consider when using the simulation method in the future consulting project.

• Journal of Veterinary Clinics
• /
• v.18 no.2
• /
• pp.124-132
• /
• 2001

The purpose of this study is to know whether single layer continuous connell suture is an acceptable alternative to simple interrupted approximating suture for end-to-end intestinal anastomosis in dogs. Fourteen mixed-breed dogs weighing 2 to 5 kg were allotted to group treated with simple interrupted approximating suture (Group I) and group treated with single layer continuous Connell suture (Group II), each of 7 dogs. All dogs in each suture pattern were compared with time for total operation ad suture elapsed for intestines to anastomose, clinical signs, changing of pre-and postoperative luminal size, status of feces, adhesion at anastomotic site for 14 days after operation. Time for total operation and suture time for intestinal anastomosis were none significant between Group I and Group II, although those in Group II was about 3 minutes shorter than those in Group I, respectively. Group I spent average 47.08${\pm}$11.10 minutes on total operation, 20.97${\pm}$5.54 minutes on suture time for intestinal anastomosis and Group II spent average 44.74${\pm}$7.77 minutes, 17.73${\pm}$3.05 minutes, respectively. All dogs were no special differences in vitality, vomiting, appetite between Group I and Group II for 14 days after operation. All dogs, except one dog in Group I, had showed normal vitality and appetite since 6~8 days after operation. Initial return of fecal passage showed in all dogs before 6 days after operation and thereafter most dogs showed normal feces. According to results, it was thought that all dogs with normal vitality and appetite before 8 days had showed good prognosis. There were no changes of intestinal luminal size in 2 dogs performed Group In and one dog performed Group II between at operation and 14 days after operation. Narrowing rate of intestinal lumen in Group I was average 9.3% of the normal diameter, whereas in Group II, 9.5% of normal diameter. In complications after operation, only one dog in Group I showed intestinal intussusception but the others didn't. Length of adhesion was measured between intestinal anastomotic site and omental graft. Length of adhesion in dogs performed Group II was mostly shorter than that of Group I. Adhesion with proximate intestines occurred in five dogs, which consisted of 3 dogs performed Group I and 2 dogs performed Group II. Concurrently, they had a great length of adhesion between anastomotic site and omental graft. There were no great differences between Group I and Group II about speed of operation, clinical signs, complications such as leakage and stricture. And all dogs performed intestinal anastomosis showed good clinical condition and prognosis. In conclusion, Single layer continuous Connell suture can safely perform an intestinal anastomosis and be an alternative of simple interrupted approximating suture in aspect of speed clinically.