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Radiofrequency thermal Shrinkage for Elongated Anterior Cruciate Ligament after Anterior Cruciate Ligament Reconstruction (전방십자인대 재건술 이후 이완된 전방십자인대에 시행한 고주파 에너지 열 수축)

  • Kim, Yeung-Jin;Chun, Churl-Hong;Kim, Tae-Kyun;Yang, Hwan-Deok;Kim, Hyoung-Joon;Kim, Young-Jin
    • Journal of Korean Orthopaedic Sports Medicine
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    • v.7 no.1
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    • pp.27-32
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    • 2008
  • Purpose: To evaluate the clinical results of the patients who underwent radiofrequency thermal shrinkage (RFTS) for treatment of anterior cruciate ligament (ACL) laxity after ACL reconstruction. Material and Methods: From October 1999 to March 2006, we performed 133 cases of ACL reconstruction. Among them we experienced 16 patients who had the laxity of reconstructed ACL in second look arthroscopy. Mean follow-up was 20.4 months. Mean age was 33.5 years. 12 cases were male and 4 cases were female. The elongated ACL were treated by bipolar radiofrequency energy with an output of grade II. Subjective and objective parameters were utilized in analyses, such as: the mean range of motion, Lysholm knee score, Tegner activity score, Lachman test, IKDC score. Wilcoxon signed-rank test was used to perform the data analysis. P<0.05 was considered to be statistically significant. Results: Postoperative mean Lysholm knee score (preop: $82.2{\pm}5.2(77{\sim}85))$ (P=0.04), postop: $85.2{\pm}4.8$(82-90)) and anterior displacement by the Telos stress test (preop: $5.4{\pm}4.6(3{\sim}10)mm$, postop: $2.1{\pm}1.9(0{\sim}4)mm)$ (P=0.02), Lachman's test, and IKDC scores (P=0.04) demonstrated significant differences statistically compared to the preoperative. There were no statistical differences in mean range of motion, Tegner activity scale. Conclusions: Arthroscopic shrinkage for the ACL laxity after ACL reconstruction with radiofrequency device showed good clinical results and was applicable operative technique.

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Effect of Radiation Dose for Radiotherapy on Ovarian Follicle Atresia in Rat (치료 방사선량이 쥐의 난포 퇴축에 미치는 영향)

  • Lee, Won-Jeong;Seon, Jong-Ryul;Yoo, Se-Jong;Ahn, Bong-Seon
    • Journal of Radiation Protection and Research
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    • v.37 no.4
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    • pp.208-212
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    • 2012
  • In previous studies, ovarian follicle in rat has been used a higher radiation dose than that for cancer radiotherapy in clinical practice. The aim of this study was to evaluate the effect of radiation dose used for cancer radiotherapy on ovarian follicle atresia in rat. Mice of 4-week-old female were whole body irradiated with 2 cGy or 2 Gy (Mevatron 67, Siemens, Germany) and sacrificed by cervical dislocation. Ovaries were collected at 24 hours after irradiation to observe the degree of follicular atresia. Ovaries were fixed in neutral formaldehyde solution for 24 hours and embedded with paraffin. Cutted in $5{\mu}m$ thickness with microtome and stained with hematoxylin and eosin (H&E) and TUNEL immunohistochemical stain, and examined histologically under a light microscope. All data were presented as mean ${\pm}SD$, calculating the ratio of normal or atretic follicles to total ovarian follicles. Statistical analysis was performed by the Mann Whitney test using the SPSS ver 19.0. Ratio of atretic to total follicles of 2 Gy group was significantly higher than control or 2 cGy groups (p<0.05). Ratio of normal to total follicles of 2 Gy group was significantly lower than control group in preantral follicle (64.0 vs. 87.7, p=0.027). Ratio of normal to total follicles of 2 cGy group was significantly increased more than control or 2 Gy groups in antral follicle, and there were no significant difference between control and 2 Gy groups (p=0.522). Radiation dose of 2 Gy for cancer radiotherapy have a significant effect on ovarian follicle atresia in rat.

Clinical study on the comparison of gold and zirconia wear in an implant-supported fixed prosthesis (임플란트 지지 고정성 보철물에서 금과 지르코니아의 마모 비교에 대한 임상 연구)

  • Kim, Jee-Hwan;Yang, Seung-Won;Oh, NamSik
    • Journal of Dental Rehabilitation and Applied Science
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    • v.33 no.4
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    • pp.252-259
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    • 2017
  • Purpose: The purpose of this study was to compare and analyze the wear of a prosthesis for 6 months after restoration with implant-supported fixed dental prosthesis made of either zirconia or gold. Materials and Methods: This study was conducted on patients requiring implant-supported fixed dental prostheses on first or second molar from January, 2015 to January, 2016. A total of 47 prostheses and antagonists were examined. Occlusal surface was recorded by impression of each prosthesis and antagonist 1 week and 6 months after prosthesis delivery. The digital files were created by impression scan. Occlusal shapes of 1 week and 6 months were compared and wear of prostheses and antagonists was analyzed. The Mann-Whitney test was used to analyzed the result data underwent normality test using SPSS (Version 23.0, IBM Corporation) Results: Mann-Whitney test revealed that there was no statistically significant difference in the median amount of mean vertical wear for 6 months in zirconia ($50.84{\mu}m$) and gold ($42.84{\mu}m$) prostheses (P > 0.05). When the opposing teeth were natural, the median amount of mean vertical wear of zirconia and gold prostheses was $47.72{\mu}m$ and $41.97{\mu}m$, respectively, and the median amount of mean vertical wear of enamel was $47.26{\mu}m$ and $44.59{\mu}m$, respectively. Statistical analysis showed no significant difference (P > 0.05). Conclusion: Despite the short study period and the small number of experimental groups, zirconia and gold showed no significant difference in wear during the first 6 months. Opposing natural enamel also showed no significant difference in the wear.

An Analysis of Socio-Economic Factors Associated with Private Forest Owners' Knowledge of Forestry Practice (사유림소유자(私有林所有者)의 임업지식수준(林業知識水準)에 영향(影響)을 미치는 사회경제적(社會經濟的) 제요인(諸要因)의 분석(分析))

  • Cho, Eung Hyouk;Koo, Sam Hoe
    • Journal of Korean Society of Forest Science
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    • v.66 no.1
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    • pp.37-44
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    • 1984
  • The study was carried out to investigate the relationship of certain socio-economic factors to the private owner's knowledge of forestry practices. The dependent variable was knowledge level in forestry, and the six independent variables were owner's age, educational level, forestland area, socio-economic status, communication and socio-psychological factors. For the study the data were collected by interviewing 258 private forest owners, and analized primarily by multiple correlation statistical technique. The sampled private owners were grouped into two categories: the common owners and model owners. 1) The average score of forestry knowledge of common owners was lower than that of model owners, and the difference was about 15 scores. The scores of other independent variables such as age, educational level, forestland area, socio-economic status, communication and socio-psychological factors of common owners were also significantly lower than those of model owners. 2) The common owner's knowledge of forestry practice were positively correlated with educational level, socio-psychological and communication variables. On the other hand, the model owner's were negatively correlated with the educational level, but positively with the socio-economic status and the socio-psychological variables. 3) The multiple correlation coefficient between the common owner's knowledge scores and six independent variables was 0.5667. About 31.46 percent of the variance of this knowledge could be explained by the communication variable, and other 1.42 percent by the socio-psychological factor. In the case of model owners, the multiple correlation was 0.5332, and about 16.62 percent of the variance of the knowledge could be explained by the communication variable, and ls.y percent by the socio-psychological factor. 4) The opportunity of communication contact through the mass media, personal communication and owner's social participation should be augmented for the effective forestry extension works, because it is one of the results of the study that the private forest owner's knowledge in forestry was greatly affected by communication variable.

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Diagnostic Performance of Combined Single Photon Emission Computed Tomographic Scintimammography and Ultrasonography Based on Computer-Aided Diagnosis for Breast Cancer (유방 SPECT 및 초음파 컴퓨터진단시스템 결합의 유방암 진단성능)

  • Hwang, Kyung-Hoon;Lee, Jun-Gu;Kim, Jong-Hyo;Lee, Hyung-Ji;Om, Kyong-Sik;Lee, Byeong-Il;Choi, Duck-Joo;Choe, Won-Sick
    • Nuclear Medicine and Molecular Imaging
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    • v.41 no.3
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    • pp.201-208
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    • 2007
  • Purpose: We investigated whether the diagnostic performance of SPECT scintimammography (SMM) can be improved by adding computer-aided diagnosis (CAD) of ultrasonography (US). Materials and methods: We reviewed breast SPECT SMM images and corresponding US images from 40 patients with breast masses (21 malignant and 19 benign tumors). The quantitative data of SPECT SMM were obtained as the uptake ratio of lesion to contralateral normal breast. The morphologic features of the breast lesions on US were extracted and quantitated using the automated CAD software program. The diagnostic performance of SPECT SMM and CAD of US alone was determined using receiver operating characteristic (ROC) curve analysis. The best discriminating parameter (D-value) combining SPECT SMM and the CAD of US was created. The sensitivity, specificity and accuracy of combined two diagnostic modalities were compared to those of a single one. Results: Both SPECT SMM and CAD of US showed a relatively good diagnostic performance (area under curve = 0.846 and 0.831, respectively). Combining the results of SPECT SMM and CAD of US resulted in improved diagnostic performance (area under curve =0.860), but there was no statistical differerence in sensitivity, specificity and accuracy between the combined method and a single modality. Conclusion: It seems that combining the results of SPECT SMM and CAD of breast US do not significantly improve the diagnostic performance for diagnosis of breast cancer, compared with that of SPECT SMM alone. However, SPECT SMM and CAD of US may complement each other in differential diagnosis of breast cancer.

Correlation between Sleep Disorders and Sleepy Drivers (수면장애와 졸음운전의 상관성)

  • Kim, Ki-Bong;Sung, Hyun-Ho;Park, Sang-Nam;Kim, Bok-Jo;Park, Chang-Eun
    • Korean Journal of Clinical Laboratory Science
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    • v.47 no.4
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    • pp.216-224
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    • 2015
  • This study aims to identify the prevalence of sleep related disease in those who experienced car accidents caused by drowsy driving. To this end, a survey of usual sleep habits, polysomnography, and multiple sleep latency tests were conducted in 34 persons who experienced an accident after normal sleep (Group 1), 22 persons who experienced an accident after abnormal sleep (Group 2), and 17 persons who was proven to be normal as a result of polysomnography and had no accident (Group 3). In all, 192 persons responded to the preliminary survey and the results were compared and analyzed. Crossover analysis was conducted to test the homogeneity of statistical characteristics, and the physical characteristics by age were analyzed. In the survey of sleeping habits, there was a significance between groups in how often they woke up while asleep (p<0.01), how difficult it was to go back to sleep again after waking up from sleep (p<0.05), how early they woke up in the morning (p<0.05), how difficult it was to get up in the morning (p<0.05), how sleepy they felt in the daytime (p<0.01), and how tired they felt in the daytime (p<0.01). Furthermore, among 56 subjects who had an accident during drowsy driving, 94.6% (53 persons) were found to have sleep related diseases. This suggests that car accidents during drowsy driving is not simply caused by temporary lack of sleep but by sleep related diseases even when sleep is adequate, leading to car accidents. Therefore, this study is significant identifying the association between car accidents during drowsy driving and sleep related disorders. Furthermore, the data would be considered basic to prepare social measures against drowsy driving related to such sleep related disorders.

Correlation of Effective Dose and BMI in Radioiodine($^{131}I$) Therapy (방사성옥소($^{131}I$) 치료 시 유효선량과 체질량지수의 상관관계)

  • Shin, Gyoo-Seul;Kim, Gun-Jae;Dong, Kyung-Rae;Kim, Hyun-Soo
    • Journal of radiological science and technology
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    • v.31 no.1
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    • pp.11-16
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    • 2008
  • Purpose : The aim of this study was to predict radiation dose at 1 meter with BMI(body mass index) in thyroid cancer patients treated with radio-iodine and provide the efficient guideline in the management of patients. Methods : 140 patients from thyroidectomy for thyroid cancer were enrolled. All subjects under went 150 mCi radio-iodine therapy and performed whole body scan 1 week later. BMI(weight divided by square of height) was calculated to evaluate the amount of fatty tissue indirectly. The radiation dose at 1 meter was measured initially and on 2nd days. the relation of values with BMI were analyzed statically. As for the method of statistical analysis, using Med calc Version 9,2,2,0 Program. Results : (1) The initial effective dose was inversely correlated with the BMI. Significance level was 0.0004. (2) We obtained the following formula from the data of initial effective dose and BMI: Y = -30.91X + 350.4(${\mu}Sv/h$)(Y: initial radiation dose, x: Group). (3) After 21.55 hours, than radiation dose was less than those recommended by ICRP or NRC in 53% of the population. Conclusion : Using BMI, the initial radiation dose and 2nd days dose can be predicted in thyroid cancer patients before radio-iodine therapy. It may be used for predicting the time of discharge and control the isolation room. We were able to predict the radiation exposure after discharge using this calculated value.

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The Comparison of Clinical Outcomes of Off-Pump versus On-Pump Coronary Artery Bypass Grafting in High Risk Patients (고위험군 환자에서 시행한 On-Pump CABG와 Off-Pump CABG의 비교연구)

  • 윤영남;이교준;김치영;안지영;오영준;유경종
    • Journal of Chest Surgery
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    • v.37 no.9
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    • pp.749-754
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    • 2004
  • Off-pump coronary artery bypass grafting (Off-Pump CABG) has been proven to have less morbidity and to facilitate early recovery. High-risk surgical patients may have benefitted by avoiding the adverse effects of the cardiopulmonary bypass. We compared the effectiveness of Off-Pump CABG with that of coronary artery bypass using cardiopulmonary bypass (On-Pump CABG) in high-risk patients. Material and Method: 682 patients (424 Off-Pump CABG and 258 On-Pump CABG) underwent isolated coronary artery bypass grafting between January 2001 and June 2003. Patients who were considered high risk were selected High risk is defined as the presence of one or more of nine adverse prognostic factors. Data were collected from 492 patients in Off-Pump CABG and 100 in On-Pump CABG for risk factors, extent of coronary disease, and in-hospital outcomes. Result: Off-Pump CABG group and On-Pump CABG group did not show differences in their preoperative risk factors. We used more arterial grafts in Off-Pump CABG group (p < 0.05). Postoperative results showed that operative mortality (0.5% in Off-Pump CABG versus 2.0% in On-Pump CABG), renal failure (2.6% in Off-Pump CABG versus 7.0% in On-Pump CABG), and perioperative myocardial infarction (1.5% in Off-Pump CABG versus 1.0% in On-Pump CABG) did not differ significantly. However, Off-Pump CABG had shorter mean operation time (p<0.05), lower mean CK-MB level (p <0.05), lower rate of usage of inotropics (p < 0.05), shorter mean ventilation time (p <0.05), lower perioperative stroke (0% versus 2.0%), and shorter length of stay (p < 0.05) than On-Pump CABG. On-Pump CABG had more distal grafts (p<0.05) than Off-Pump CABG. Although Off-Pump CABG and On-Pump CABG did not show statistical differences in mortality and morbidity was more frequent in CABG. Conclusion: Off-Pump CABG reduces morbidity and favors hospital outcomes. Therefore, Off-Pump CABG is safe, reasonable and may be a preferable operative strategy for high-risk patients.

Effect of RGD peptide coating of implant titanium surface on human mesenchymal stem cell response (양극산화 티타늄 표면에 서로 다른 RGD 펩타이드 코팅 방법이 인간간엽줄기세포 반응에 미치는 영향)

  • Kim, Min-Su;Jeong, Chang-Mo;Jeon, Young-Chan;Ryu, Jae-Jun;Huh, Jung-Bo;Yun, Mi-Jung
    • The Journal of Korean Academy of Prosthodontics
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    • v.49 no.3
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    • pp.245-253
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    • 2011
  • Purpose: The aim of this in vitro study was to estimate surface characteristic after peptide coating and investigate biological response of human mesenchymal stem cell to anodized titanium discs coated with RGD peptide by physical adhesion and chemical fixation. Materials and methods: Fluorescence isothiocyanate (FITC) modified RGD-peptide was coated on the anodized titanium discs (diameter 12 mm, height 3 mm) using two methods. One was physical adhesion method and the other was chemical fixation method. Physical adhesion was performed by dip and dry procedure, chemical fixation was performed by covalent bond via silanization. In this study, human mesenchymal stem cell was used for experiments. The experiments consisted of surface characteristic evaluation after peptide coating, analysis about cell adhesion, proliferation, differentiation, and mineralization. Obtained data are statistically treated using Kruskal-Wallis test and Bonferroni test was performed as post hoc test (P=.05). Results: The evaluation of FE-SEM images revealed no diffenrence at micro-surfaces between each groups. Total coating dose was higher at physical adhesion experimental group than at chemical fixation experimental group. In cell adhesion and proliferation, RGD peptide coating did not show a statistical significance compared with control group (P>.05). In cell differentiation and mineralization, physical adhesion method displayed significantly increased levels compared with control group and chemical fixation method (P<.05). Conclusion: RGD peptide coating seems to enhance osseointegration by effects on the response of human mesenchymal stem cell. Especially physical adhesion method showed more effective than chemical fixation method on response of human mesenchymal stem cell.

Simulation of Drying Grain with Solar-Heated Air (태양에너지를 이용한 곡물건조시스템의 시뮬레이션에 관한 연구)

  • 금동혁;김용운
    • Journal of Biosystems Engineering
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    • v.4 no.2
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    • pp.65-83
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    • 1979
  • Low-temperature drying systems have been extensively used for drying cereal grain such as shelled corn and wheat. Since the 1973 energy crisis, many researches have been conducted to apply solar energy as supplemental heat to natural air drying systems. However, little research on rough rice drying has been done in this area, especially very little in Korea. In designing a solar drying system, quality loss, airflow requirements, temperature rise of drying air, fan power and energy requirements should be throughly studied. The factors affecting solar drying systems are airflow rate, initial moisture content, the amount of heat added to drying air, fan operation method and the weather conditions. The major objectives of this study were to analyze the effects of the performance factors and determine design parameters such as airflow requirements, optimum bed depth, optimum temperature rise of drying air, fan operation method and collector size. Three hourly observations based on the 4-year weather data in Chuncheon area were used to simulate rough rice drying. The results can be summarized as follows: 1. The results of the statistical analysis indicated that the experimental and predicted values of the temperature rise of the air passing through the collector agreed well. 2. Equilibrium moisture content was affected a little by airflow rate, but affected mainly by the amount of heat added, to drying air. Equilibrium moisture content ranged from 12.2 to 13.2 percent wet basis for the continuous fan operation, from 10.4 to 11.7 percent wet basis for the intermittent fan operation respectively, in range of 1. 6 to 5. 9 degrees Centigrade average temperature rise of drying air. 3. Average moisture content when top layer was dried to 15 percent wet basis ranged from 13.1 to 13.9 percent wet basis for the continuous fan operation, from 11.9 to 13.4 percent wet basis for the intermittent fan operation respectively, in the range of 1.6 to 5.9 degrees Centigrade average temperature rise of drying air and 18 to 24 percent wet basis initial moisture content. The results indicated that grain was overdried with the intermittent fan operation in any range of temperature rise of drying air. Therefore, the continuous fan operation is usually more effective than the intermittent fan operation considering the overdrying. 4. For the continuous fan operation, the average temperature rise of drying air may be limited to 2.2 to 3. 3 degrees Centigrade considering safe storage moisture level of 13.5 to 14 perceut wet basis. 5. Required drying time decrease ranged from 40 to 50 percent each time the airflow rate was doubled and from 3.9 to 4.3 percent approximately for each one degrees Centigrade in average temperature rise of drying air regardless of the fan operation methods. Therefore, the average temperature rise of drying air had a little effect on required drying time. 6. Required drying time increase ranged from 18 to 30 percent approximately for each 2 percent increase in initial moisture content regardless of the fan operation methods, in the range of 18 to 24 percent moisture. 7. The intermittent fan operation showed about 36 to 42 percent decrease in required drying time as compared with the continuous fan operation. 8. Drymatter loss decrease ranged from 34 to 46 percent each time the airflow rate was doubled and from 2 to 3 percent approximately for each one degrees Centigrade in average temperature rise of drying air, regardless of the fan operation methods. Therefore, the average temperature rise of drying air had a little effect on drymatter loss. 9. Drymatter loss increase ranged from 50 to 78 percent approximately for each 2 percent increase in initial moisture content, in the range of 18 to 24 percent moisture. 10. The intermittent fan operation: showed about 40 to 50 percent increase in drymatter loss as compared with the continuous fan operation and the increasing rate was higher at high level of initial moisture and average temperature rise. 11. Year-to-year weather conditions had a little effect on required drying time and drymatter loss. 12. The equations for estimating time required to dry top layer to 16 and 1536 wet basis and drymatter loss were derived as functions of the performance factors. by the least square method. 13. Minimum airflow rates based on 0.5 percent drymatter loss were estimated. Minimum airflow rates for the intermittent fan operation were approximately 1.5 to 1.8 times as much as compared with the continuous fan operation, but a few differences among year-to-year. 14. Required fan horsepower and energy for the intermittent fan operation were 3. 7 and 1. 5 times respectively as much as compared with the continuous fan operation. 15. The continuous fan operation may be more effective than the intermittent fan operation considering overdrying, fan horsepower requirements, and energy use. 16. A method for estimating the required collection area of flat-plate solar collector using average temperature rise and airflow rate was presented.

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