• 대한지리학회지
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• 제41권5호
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• pp.545-560
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• 2006

본 연구의 목적은 16세기에서 18세기에 이르기까지의 프랑스의 국가 형성과 지도학 발달의 관계를 고찰하는 것이다. 이를 위하여 먼저 영토의 방어와 확장을 목적으로 하는 군사지도의 발달을 살펴보았다. 둘째, 식민지 확장의 수단으로 사용되는 해외 지도의 발달과정을 고찰하였다. 세 번째로 국가 표상으로서의 국가 기본 지도의 발달과정을 살펴보았다. 네 번째로, 국민의식 함양을 목적으로 한 아틀라스의 발달과정을 고찰하였으며, 마지막으로 지도가 프랑스의 국가형성에 미친 영향에 대해 종합적으로 논의하였다.

• BMB Reports
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• 제46권2호
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• pp.113-118
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• 2013

TTRAP is a multi-functional protein that is involved in multiple aspects of cellular functions including cell proliferation, apoptosis and the repair of DNA damage. Here, we demonstrated that the lentivirus-mediated overexpression of TTRAP significantly inhibited cell growth and induced apoptosis in osteosarcoma cells. The ectopic TTRAP suppressed the growth and colony formation capacity of two osteosarcoma cell lines, U2OS and Saos-2. Cell apoptosis was induced in U2OS cells and the cell cycle was arrested at G2/M phase in Saos-2 cells. Exogenous expression of TTRAP in serum-starved U2OS and Saos-2 cells induced an increase in caspase-3/-7 activity and a decrease in cyclin B1 expression. In comparison with wild-type TTRAP, mutations in the 5'-tyrosyl-DNA phosphodiesterase activity of TTRAP, in particular $TTRAP^{E152A}$, showed decreased inhibitory activity on cell growth. These results may aid in clarifying the physiological functions of TTRAP, especially its roles in the regulation of cell growth and tumorigenesis.

• 국제지역연구
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• 제15권2호
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• pp.403-425
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• 2011

인권과 개발의 상관성에 대한 담론은 크게 인권과 개발이 이중적(duplicative)이거나 상호경쟁관계로 가정하는 입장과 인권과 개발 서로 간에 상호 보완적 관계라는 입장으로 구분된다. 국제인권규범을 준수하고 개발원조정책에서 인권적 접근을 시도하려는 노력과 빈곤과 인권의 내재적 관계를 접어두고 성장과 개발을 우선시하는 정책간의 긴장상태가 유지되고 있다. OECD/DAC 국가 중 유일하게 캐나다가 2008년 ODA가 국제인권기준의 가치와 합의에 충족해야 하는 점을 규정한 ODA 책무법을 채택하였다. 본 논문은 이 점에 주목하여 다른 선진공여국과는 달리 중견국가(middle power)로서 우리와 비슷한 경제규모와 정치적 위상을 가진 캐나다가 어떠한 배경과 과정을 거쳐 인권을 우선시 하는 대외원조법안을 제정하였는지를 설명하고자 한다. 캐나다는 인간안보 영역을 틈새영역으로 생각하며 신 외교 방침의 일환으로 인권을 강조하는 중견국가로써의 특징을 보여준다. 탈냉전과 함께 규범을 창출하고 촉진하는 중견국가로서의 외교노선 수립과 함께 신자유주의에 입각한 원조정책에 대한 반성 또한 가치중심적 대외원조정책 수립과 인권을 강조하는 법안을 제정하는데 호의적인 환경 속에서 '선택적 국제주의'라는 틈새외교가 강조되기 시작하였다. 전통적으로 북유럽국가와 함께 '인도적 목적'의 ODA를 중시하고 있는 캐나다는 인권을 표방하는 원조정책을 통해 국가 이미지를 제고하려는 노력이 시민사회의 적극적 동의와 함께 ODA책무법의 탄생을 가능하게 한 것으로 보인다.

• Asian-Australasian Journal of Animal Sciences
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• 제27권2호
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• pp.237-246
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• 2014

Two experiments were conducted to evaluate the efficacy of feeding an Escherichia coli (E. coli) derived phytase to pigs fed P deficient, corn-soybean meal diets. In Exp. 1, one hundred and twenty crossbred piglets ($9.53{\pm}0.84$ kg) were allocated to one of five treatments which consisted of four low P diets (0.61% Ca, 0.46% total P and 0.24% non-phytate P) supplemented with 0, 500, 1,000, or 20,000 FTU/kg E. coli phytase as well as a positive control formulated to be adequate in all nutrients (0.77% Ca, 0.62% total P and 0.42% non-phytate P). The treatments were applied to six pens with four pigs per pen for 28 days. In Exp. 2, ten crossbred pigs ($19.66{\pm}1.16$ kg) fitted with ileal T-cannula were used in a nutrient balance study. The pigs were assigned to treatments similar to those used in Exp. 1 in a doubly replicated $5{\pm}4$ incomplete Latin square design (5 diets with 4 periods). Each period consisted of a 5-d adjustment period followed by a 3-d total collection of feces and urine and then a 2-d collection of ileal digesta. Supplementation with phytase linearly increased (p<0.05) weight gain, feed intake, feed efficiency, bone breaking strength and fat-free dry and ash bone weight. There were linear increases (p<0.01) in the apparent ileal digestibility (AID) of DM, GE, CP, Ca, total P, inositol hexaphosphate ($IP_6$) and some AA with increasing dose of E. coli phytase. Pigs fed 20,000 FTU/kg had a greater (p<0.05) AID of IP6 (80% vs 59% or 64%, respectively) than pigs fed diets with 500 or 1,000 FTU/kg phytase. There were linear increases (p<0.05) in the total tract digestibility of Ca, total P, Na, K, Mg, and Zn as well as in the retention of Mg and Zn with increased phytase dose. The retention and utilization of Cu, and the total tract digestibility of CP and Cu quadratic increased (p<0.05) with increased phytase dose. In conclusion, supplementation of 500 FTU of phytase/kg and above effectively hydrolyzed phytate in low-P corn-soybean diets for pigs. In addition, a super dose of phytase (20,000 FTU/kg) hydrolyzed most of the IP6 and consequently further improved mineral use, protein utilization and performance.

• Asian-Australasian Journal of Animal Sciences
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• 제30권7호
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• pp.999-1005
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• 2017

Objective: Two experiments were conducted to determine the content of digestible energy (DE) and metabolizable energy (ME) as well as the apparent ileal digestibility (AID) and standardized ileal digestibility (SID) of crude protein (CP) and amino acids (AA) in barley grains obtained from Australia, France or Canada. Methods: In Exp. 1, 18 growing barrows ($Duroc{\times}Landrace{\times}Yorkshire$; $31.5{\pm}3.2kg$) were individually placed in stainless-steel metabolism crates ($1.4{\times}0.7{\times}0.6m$) and randomly allotted to 1 of 3 test diets. In Exp. 2, eight crossbred pigs ($30.9{\pm}1.8kg$) were allotted to a replicate $3{\times}4$ Youden Square designed experiment with three periods and four diets. Two pigs received each diet during each test period. The diets included one nitrogen-free diet and three test diets. Results: The relative amounts of gross energy (GE), CP, and all AA in the Canadian barley were higher than those in Australian and French barley while higher concentrations of neutral detergent fiber, acid detergent fiber, total dietary fiber, insoluble dietary fiber and ${\beta}-glucan$ as well as lower concentrations of GE and ether extract were observed in the French barley compared with the other two barley sources. The DE and ME as well as the SID of histidine, isoleucine, leucine and phenylalanine in Canadian barley were higher (p<0.05) than those in French barley but did not differ from Australian barley. Conclusion: Differences in the chemical composition, energy content and the SID and AID of AA were observed among barley sources obtained from three countries. The feeding value of barley from Canada and Australia was superior to barley obtained from France which is important information in developing feeding systems for growing pigs where imported grains are used.

• 대한기계학회논문집
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• 제2권2호
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• pp.42-46
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• 1978

Thermal conductivities of Freon-12 and Freon-22 were measured at room temperature up to 35 MPa with the aid of transient hot wire method. Glycerin was used to check the performance of the experimental equipment. The thermal conductivities of Freon-12 and Freon-22 at the maximum pressure, 35 MPa, were increased by 25% approximately for those at satufated state.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2003년도 춘계학술대회
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• pp.157-162
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• 2003

Singular stress fields around three-dimensional wedges are examined, and the near-tip intensity is calculated via the two-state M-integral with the aid of the domain integral representation. A numerical example demonstrates the effectiveness and accuracy of the present scheme for computing the stress intensities of singular stresses near the generic three-dimensional wedges.

• Kyungpook Mathematical Journal
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• 제49권4호
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• pp.651-666
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• 2009

With the aid of weakly weighted sharing and a recently introduced sharing notion in [3] known as relaxed weighted sharing we investigate the uniqueness of meromorphic functions sharing a small function with its differential polynomials. Our results will improve and supplement all the results obtained by Zhang and Yang [17] as well as a substantial part of the results recently obtained by the present author [2] and thus provide a better answer to the questions posed by Yu [14] in this regard.

• 대한산업공학회지
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• 제4권1호
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• pp.29-32
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• 1978

We obtain the minimum variance unbiased estimate of system reliability when a system consists of n components whose life times are assumed to be independent and identically distributed either negative exponential or geometric random variables. For the case of a negative exponential life time, we obtain the minimum variance unbiased estimate of the probability density function of the i-th order statistic.

• Structural Engineering and Mechanics
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• 제41권5호
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• pp.663-673
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• 2012

A number of mode shape-based structure damage identification methods have been verified by numerical simulations or experiments for on-line structure health monitoring (SHM). However, many of them need a baseline mode shape generated by the healthy structure serving as a reference to identify damages. Otherwise these methods can hardly perform well when multiple cracks conditions occur. So it is important to solve the problems above. By aid of the fractal dimension method (FD), Qiao and Wang proposed a generalized fractal dimension (GFD) to detect the delamination damage. As a modification of GFD, Qiao and Cao proposed the approximate waveform capacity dimension (AWCD) technique to simplify the calculation of fractal and overcome the false peak appearing in the high mode shapes. Based on their valued work, this paper combined and applied the AWCD method and curvature mode shape data to detect multiple damages in beam. In the end, the identification properties of the AWCD for multiple damages have been verified by groups of Monte Carlo simulations and experiments.