• Journal of the Korean Statistical Society
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• v.14 no.1
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• pp.7-17
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• 1985

Data set generated by teh bivariate dichotomous choice made by individuals often occurs in practice. This paper presents general model of how such data set is generated as well as methods of estimation. The M.L.E. is examined and found to be computationally burdensome. A simpler estimator, the bivariate dichotomous two-stage estimator, is suggested as an alternative. The two-stage estimator is found to be as efficient as the M.L.E.

• Herbal Formula Science
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• v.24 no.1
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• pp.17-30
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• 2016

Objectives Rehmanniae Radix Preparata was prepared in the traditional Rehmanniae Radix Preparata preparation method set forth in the 『Treasured Mirror of Eastern Medicine(Donguibogam)』 with a view to measuring the contents of 5-Hydroxymethyl-2-furaldehyde(5-HMF) at individual stages of steaming and sundrying and identifying new chemical components.Methods Based on the traditional Rehmanniae Radix Preparata preparation method set forth in the 『Treasured Mirror of Eastern Medicine』, Rehmanniae Radix Preparata steamed and sundried once through nine times was prepared. Thereafter, 5-HMF contents were analyzed and new chemical components were identified in the Rehmanniae Radix Preparata using Waters HPLC e2695, 2640 detectors, a Waters Acquity UPLC system, and a Micromass Q-TOF Premier mass spectrometer.Results The Rehmanniae Radix Preparata preparation method set forth in the 『Treasured Mirror of Eastern Medicine』 is a unique preparation method in Republic of Korea different from that in China. In the first stage of the method, fresh Rehmanniae Radix Crudus was divided into high quality, medium quality, and low quality ones named Rehmanniae Radix Crudus (Caelum)(天黃), Rehmanniae Radix Crudus (Homo)(人黃), and Rehmanniae Radix Crudus (Terra)(地黃) respectively to use Rehmanniae Radix Crudus (Caelum) and Rehmanniae Radix Crudus (Homo) for preparation of juice while using Rehmanniae Radix Crudus (Terra) to make Rehmanniae Radix Preparata. In the second stage, Rehmanniae Radix Crudus (Caelum) and Rehmanniae Radix Crudus (Terra) were made into juice and Rehmanniae Radix Crudus (Terra) was soaked in the juice. In the third stage, among auxiliary materials, rice wine named Purum Vinum Oryzae(淸酒) brewed from sticky rice was sprinkled on Rehmanniae Radix Crudus (Terra) to the extent that Rehmanniae Radix Crudus (Terra) became wet. In the fourth stage, Rehmanniae Radix Preparata steamed in earthenware steamer was dried under natural sunlight. The contents of 5-HMF in Rehmanniae Radix Preparata steamed and sundried once through nine times were shown to be below 0.1% in all cases. Pomolic acid was identified as a new chemical component.Conclusions In conclusion, the Rehmanniae Radix Preparata preparation method set forth in the 『Treasured Mirror of Eastern Medicine』 is thought to be a unique preparation method in South Korea in which Rehmanniae Radix Preparata is completed through the first stage in which fresh Rehmanniae Radix Crudus collected from fields is divided into high, medium, and low quality ones and fresh Rehmanniae Radix Crudus juice is made, the second stage in which the high quality fresh Rehmanniae Radix Crudus is soaked in the fresh Rehmanniae Radix Crudus juice, the third stage in which the fresh Rehmanniae Radix Crudus is steamed, and the fourth stage in which the steamed Rehmanniae Radix Crudus is dried.

• Korean Institute of Interior Design Journal
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• v.25 no.5
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• pp.42-54
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• 2016

The purpose of this study is to provide a reference for stage planning by analyzing current state of major theaters' stage space and understanding feedback from directors belonged to theaters. Each room in total 18 theaters' stage facilities was measured and their usage and requirements were analyzed on the spot. In addition, each director provided their experiential knowledge about appropriate stage composition for musical performance. The findings are as follow: under stage machinery is not needed for musical. Tour teams prefer to use their own show-deck for set conversion. On the other hand, over stage flying system needs to be able to deal with dense, fast, and accurate scene change. The size and location of the motor room needs to be carefully considered. The number of set battens is directly linked up with the size of the motor room, which should be located lower than the gridiron. As stage sets get bigger and complicated, the number of works at the gridiron is also increasing. The grating floor has to have enough strength coping with machines lifting heavy sets. Most sound control for musical performance is being done at F.O.H. these days rather that in the sound control room. It should equip enough work area and related infra especially for tour teams. 1st gallery needs to have enough effective width, power infra for lighting fixture, and strong guardrail. Lastly, the whole process of parking-unloading-transporting equipments and sets from loading dock to stage and vice versa needs to be efficient, and this has to be carefully considered from early stage of planning.

• Proceedings of the Korean Society for Bioinformatics Conference
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• 2003.10a
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• pp.7-16
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• 2003

In this paper, we propose a probabilistic framework to predict the interaction probability of proteins. The notion of domain combination and domain combination pair is newly introduced and the prediction model in the framework takes domain combination pair as a basic unit of protein interactions to overcome the limitations of the conventional domain pair based prediction systems. The framework largely consists of prediction preparation and service stages. In the prediction preparation stage, two appearance pro-bability matrices, which hold information on appearance frequencies of domain combination pairs in the interacting and non-interacting sets of protein pairs, are constructed. Based on the appearance probability matrix, a probability equation is devised. The equation maps a protein pair to a real number in the range of 0 to 1. Two distributions of interacting and non-interacting set of protein pairs are obtained using the equation. In the prediction service stage, the interaction probability of a protein pair is predicted using the distributions and the equation. The validity of the prediction model is evaluated fur the interacting set of protein pairs in Yeast organism and artificially generated non-interacting set of protein pairs. When 80% of the set of interacting protein pairs in DIP database are used as foaming set of interacting protein pairs, very high sensitivity(86%) and specificity(56%) are achieved within our framework.

• The Journal of Internal Korean Medicine
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• v.43 no.4
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• pp.656-679
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• 2022

Objectives: The aims of this study were to evaluate the fidelity of stroke stage reporting, the timeliness of the outcome measures, and the use of the core outcome set. Methods: We searched the literature using 6 domestic databases. We selected studies that used Korean medicine interventions and targeted stroke patients with motor sequelae. We examined whether the included studies reported the stroke stage and whether they used the outcome measures in the appropriate period based on the recommendations of the "Stroke Evidence Database to Guide Effectiveness". We also confirmed the use of the essential assessment tools suggested by the core outcome set. Results: Overall, 77 studies were finally selected, with 16 (21%), 55 (71%), and 6 (8%) published on the acute, subacute, and chronic phases, respectively. Only 11 of the studies directly mentioned the stroke stage. The most commonly used assessments were the National Institutes of Health Stroke Scale, Modified Barthel Index, and Manual Muscle Testing. Only 5 studies failed to apply the stage-related outcome measures at the recommended period. The outcome variables used inadequately were the National Institutes of Health Stroke Scale, Functional Ambulation Categories, 36-Item Short Form Health Survey, and Mini-Mental State Examination. Among the core outcome set items, some studies used liver and renal function tests, but no herbal medicine safety reporting was conducted. Conclusions: In future studies, we propose to ensure accurate reporting of the stroke stage with reliable outcome measures to deliver better clinical and research outcomes. Furthermore, in future clinical studies on stroke, a standard protocol that reflects the core outcome set should be developed.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.15
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• pp.6605-6608
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• 2015

Background: Colorectal cancer is a major cause of morbidity and mortality throughout the world. Colorectal cancer screening is an optimal way for reducing of morbidity and mortality and a clinical decision support system (CDSS) plays an important role in predicting success of screening processes. DSS is a computer-based information system that improves the delivery of preventive care services. The aim of this article was to detail engineering of information requirements and work flow design of CDSS for a colorectal cancer screening program. Materials and Methods: In the first stage a screening minimum data set was determined. Developed and developing countries were analyzed for identifying this data set. Then information deficiencies and gaps were determined by check list. The second stage was a qualitative survey with a semi-structured interview as the study tool. A total of 15 users and stakeholders' perspectives about workflow of CDSS were studied. Finally workflow of DSS of control program was designed by standard clinical practice guidelines and perspectives. Results: Screening minimum data set of national colorectal cancer screening program was defined in five sections, including colonoscopy data set, surgery, pathology, genetics and pedigree data set. Deficiencies and information gaps were analyzed. Then we designed a work process standard of screening. Finally workflow of DSS and entry stage were determined. Conclusions: A CDSS facilitates complex decision making for screening and has key roles in designing optimal interactions between colonoscopy, pathology and laboratory departments. Also workflow analysis is useful to identify data reconciliation strategies to address documentation gaps. Following recommendations of CDSS should improve quality of colorectal cancer screening.

• Transactions of the Korean Society of Machine Tool Engineers
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• v.10 no.6
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• pp.8-14
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• 2001

We develop a method to analyze dynamic behavior off multi-stage gear train system. The example system consists of three shafts supported by ball bearings at the ends of them and two pairs of spur gear set. For exact analysis, the meshing tooth pair of gear set is modeled as spring and damper having time-dependent meshing stiffness and damping. The bearing is modeled as spring. The result of this analysis is compared to that of other model having mean mesh stiffness. The effect of the excitation force by the unbalance off rotor off motor is also analyzed. Finally, the change ova natural frequency of the whole system due to the change of an angle between three shafts is compared in each case, and from this analysis, the avoiding angle for design is advised.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
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• 2002.05a
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• pp.201-204
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• 2002

Kansei design knowledge acquisition stage is a crucial stage in kansei designing process and kansei engineering (KE) methodology. In kansei engineering methodology, it is essential to extract design knowledge or rules on relationships between customer's kansei and product design element. We attempt to construct a more powerful melted for extracting the design rules from kansei expremental data. We constucted a kansei experiment concerning color kansei evaluation, and analyzed the sane data by both conventional quantification theory type I and rough set theory. Finally, we compared the effectiveness of both methods for extracting rules and examined the extensions of rough set theory in kansei engineering.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2007.06a
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• pp.773-774
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• 2007

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.13 no.2
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• pp.169-175
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• 2020

This paper studied the SET situation in VLSI because the electronic devices exposed to SET can indicate irregular operation and output errors. The SET environment was established using the exponential static wave (iexp) in the fold-cascode comparator. The comparator was experimented with how it affected it by the SET. In a folded comparator that did not enter the SET situation, the propagation delay was measured at 0.26㎲ and the gain was 0.649. The MOSFET close to the output stage was measured sensitively in the folded comparator that entered the SET situation. And propagation delay was calculated from 0.36 to 0.37㎲ and the gain was 0.649. The mid-position MOSFET was calculated from 0.28 to 0.30㎲ and the gain was 0.649. The MOSFET, which is farthest from the output stage from the folded comparator, was calculated with the propagation delay between 0.25 and 0.26㎲ and the gain of 0.649. In SET situations, the MOSFET close to the output portion of the folded comparator was sensitive. And at the MOSFET far from the output, the same results were obtained as a normal folded comparator without the SET input.