• KSII Transactions on Internet and Information Systems (TIIS)
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• 제14권8호
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• pp.3201-3223
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• 2020

Wireless communication has become the promising technology in the recent times because of its applications in Internet of Things( IoT) devices. The IEEE 802.15.4e has become the key technology for IoT devices which utilizes the Time-Slotted Channel Hopping (TSCH) networks for the communication between the devices. In this paper, we develop a Two Level Scheduling Algorithm (TLSA) for scheduling multiple packets with different arrival rate at the source nodes in a TSCH networks based on the link activated by a centralized scheduler. TLSA is developed by considering three types of links in a network such as link i with packets arrival type 1, link j with packets arrival type 2, link k with packets arrival type 3. For the data packets arrival, two stages in a network is considered.At the first stage, the packets are considered to be of higher priority.At the second stage, the packets are considered to be of lower priority.We introduce level 1 schedule for the packets at stage 1 and level 2 schedule for the packets at stage 2 respectively. Finally, the TLSA is validated with the two different energy functions i.e., y = e^ax - 1 and y = 0.5x² using MATLAB 2017a software for the computation of average and worst ratios of the two levels.

• Journal of Chest Surgery
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• 제45권2호
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• pp.101-109
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• 2012

Background: A better understanding of the histopathology and molecular biology of lung cancer might improve our capability to predict the outcome for any individual patient. The purpose of this study was to evaluate several histopathologic and molecular markers in order to assess their prognostic value in stage I non-small cell lung cancer. Materials and Methods: One hundred ten patients at the Kyungpook National University Hospital were enrolled in the study. Histopathologic factors and molecular markers were selected. Results: Univariate analysis showed that the T stage, differentiation, visceral pleural invasion, and survivin expression were significantly associated with recurrence. Multivariate analysis demonstrated that differentiation and survivin overexpression emerged as independent prognostic factors of recurrence. Conclusion: In resected stage I non-small cell lung cancer, poor differentiation and survivin overexpression have been identified as independent predictors of poor disease-free survival.

• 자원환경지질
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• 제23권1호
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• pp.25-33
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• 1990

Gold-silver deposits of Deogheun and Beopjeon mines are composed of veins emplaced in Jurassic granite batholith. Based on ore structure and ore mineralogy, four distinct stages of mineral deposition are recognized in these ore deposits. Gold and silver minerals in Deogheun and Beopjeon-A ore deposits are precipitated in stage III and stage II, respectively. Mineral constituents of ores from these deposits are pyrite, sphalerite, arsenopyrite, pyrrhotite, chalcopyrite, galena, tetrahedrite, electrum, quartz and rhodochrosite. Cubanite, argentite and pyrargyrite occur only in Deogheun ore deposits. Ag content of electrum range from 42 to 66 atomic % in both ore deposits. Filling temperature of fluid inclusion from both ore deposits are as follows; stage I, $211-289^{\circ}$ ; stage II, $205-290^{\circ}$ ; stage III, $190-260^{\circ}$ ; stage IV, $136-222^{\circ}$ in Deogheun ore deposits. In Beopjeon-A ore deposits, stage I, $255-305^{\circ}$ ; stage II, $135-222^{\circ}$ ; stage III, $148-256^{\circ}$ ; stage IV, $103-134^{\circ}$. Salinities of fluid inclusions range from 1.6-8.5 wt. % equivalent NaCl in both ore deposits. Sulfur fugacities through stage II and III in Deogheun ore deposits inferred from data of mineral assemblage and fluid inclusion range from $10^{-11.0}-10^{-16.1}$1bars. Fluid pressure estimated from fluid inclusions which reveal boiling evidence range from 30-190 bars during mineralization in Deogheun ore deposits.

• Clinical and Experimental Reproductive Medicine
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• 제17권2호
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• pp.101-106
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• 1990

Serum CA 125 was measured with immunoradiometric assay in fourty-one patients of endometriosis Serum CA 125 levels (Mean ${\pm}$ SEM, U/ml)in patients with endometriosis were 13.8${\pm}$3.3 in stage I , 17.3${\pm}$3.0 in stage II, 23.4${\pm}$4.9 in stage III, and 64.5${\pm}$13.2 in stage IV, which showed increment according to the stage of endometriosis. Serum levels in stage IV only were significantly elvated than those in control (15.3${\pm}$2.2), and those in advanced stage(III and IV ; 47.1${\pm}$9.5)were significantly higher than those in earlier stages (15.9${\pm}$2.2)and control. The assay revealed a sensitivity of 31.7% and the frequency of elevated levels (> 30.3 U/ml)in stage I, II, III and IV was 9. 1%, 18.8%,33.3%, and 87.5% respectively. Sensitivity in advanced stage was higher than that in earlier stage (64.3% vs. 14.8%). There data suggest that serum CA 125 assay might be a useful diagnostic tool in the advanced stage of endometriosis.

• 미생물학회지
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• 제16권3호
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• pp.122-130
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• 1978

Saccharomyces cerevisiae J170, matant를 사용하여 YEP 배지에서 20시간 진탕 배양하여 생장이 왕성한 영양시기의 효모세포를 얻었다. 이 세포를 sporulation medium에 접종하여 $30^{\circ}C$에서 20시간 진탕 배양하면 약 80%의 ascospore를 형성함을 볼 수 있었다. 포자행성시기와 생장시기를 택하여 D-$^{14}C$-glucose 운반에 관하여 바교 검도한 결과는 다음파 같다. haploid인 포자형성시나 diploid인 생장시기의 포도당 흡수는 pH6.0에서 최대이었다. 이 두 시기의 포도당 운반은 2, 4-dinitrophenol에 의하여 저해되었으므로 포자형성기의 포도당운반도 역시 egergy를 요구하는 능동수송파 연관이 있음을 알게 되었다. 생장시기의 포도당 흡수정도는 포자형성기 보다 높았으며 이때에 fructose나 galactose와 포도당흡수의 관계는 서로 경쟁적으로 작용함을 알 수 있었다. 효모세포의 당 성분은 ribose, mannose, $\alpha$, $\beta$-glucose로 되어 있으며 특히 포자형성기의 mannose 함량은 영양세포 때보다 현저히 적었다.

• 한국세라믹학회지
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• 제22권6호
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• pp.5-8
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• 1985

Graphite has been oxidized to graphite hydrogen sulfate in concentrated $H_2SO_4$. Anodic oxidation and chemical oxidation of graphite in $H_2SO_4$ generally leads to the formation of intercalation compounds of the ionic salt type through incorporation of $H_2SO_4^-$ions and $H_2SO_4$ molecules into the graphite. Several other reactions also accur at various points of the charging cycle. But there is no satisfactory kinetics and mechanism of intercalationin graphite. We have studied them with anodic oxidation and chemical oxidation. We found six distinct phenomena between 2nd stage and 1st stage in chemical oxidation. We examined them in detail by the following in the measurements electrical oxidation. X-ray diffractions UV-Vis spectroscopy density measurements. We could obtained a equation for kinetic according to the reaction rate from this results and mechanism of intercalation between 2nd stage and 1st stage with hydrogen sulfate in graphite. Three thesis were written for the mechanism of intercalation compounds in graphite with hydrogen sulfate ; first thesis is anodic oxidation second thesis is chemical oxidation and definition of transit phase between 2nd etc the third thesis is the kinetic mechanism of intercalation compounds in graphite with Hydrogen sulfate. This thesis is the first paper among three thesis as anodic oxidation.

• Radiation Oncology Journal
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• 제2권1호
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• pp.93-100
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• 1984

Among 238 patients with Non-Hodgkin's lymphoma received radiotherapy at Yonsei Cancer center, Yonsei University Medical College, from 1970 to 1981, 30 patients presented with localized(Stage I&II ) gastrointestinal lymphomas. Retrospective analysis of these 30 cases in an attempt to evaluate the influence of various prognostic factors and the effectiveness of therapy is presented. Overall 5 year survival rate of 30 cases of primary gastrointestinal lymphoma was $48\%$. Bulk of residual disease after initial surgery and stage were significant prognostic factors. Stage I with small residual disease treated with post-op irradiation achieved $100\%$ 5 year survival rate. So above group is considered curable with surgery and post-op irradiation. $80\%$ of Stage II with large residual disease were died with intra-abdominal local tumor control failure. Stage II with small residual disease showed $31.5\%$ 5 year survival rate. Non of them died with local failure. So, we suggest that complete surgical resection of tumor mass should be attempted initially in the management of localized gastrointestinal lypmhomas and systemic chemotherapy is needed in addition to post-op irradiation in the cases of Stage II and large residual disease after initial surgery.

• 대한관절경학회지
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• 제2권2호
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• pp.159-163
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• 1998

We reviewed the cases of 35 knees of 34 patients who had arthroscopic debridement for degenerative osteoarthritis of the knee. The patients were followed up for an average of 29 months (range: 13 months to 45 months). The mean age of the patients at operation was 54 years (range: 44 years to 75 years). At the time of follow up, the patients were evaluated using the nine-point scale by Baumgaertner et al. We divided the knee into 4 stages according to the classification system by Jackson et al. Satisfactory results were achieved in 80%(stage I), 75%(stage II), 55.6%(stage III) and 25%(stage IV) of the patients. Arthroscopic debridement is of significant value in the earlier stages of degenerative osteoarthritis (stage I and II) for the symptom relief as a simple procedure with rare complication as well as in the later stages(stage III and IV) as a time buying procedure before the total knee arthroplasty.

• Communications for Statistical Applications and Methods
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• 제26권2호
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• pp.163-173
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• 2019

Simon's two-stage designs are frequently used in phase II single-arm trials for efficacy studies. A concern of safety studies is too many patients who experience an adverse event. We show that Simon's two-stage designs for efficacy studies can be similarly used to design a two-stage safety study by modifying some of the design parameters. Given the type I and II error rates and the proportion of adverse events experienced in the first stage cohort, we prescribe a procedure whether to terminate the trial or proceed with a stage 2 trial by recruiting additional patients. We study the relationship between a two-stage design with a safety endpoint and an efficacy endpoint as well as use simulation studies to ascertain their properties. We provide a real-life application and a free R package gen2stage to facilitate direct use of two-stage designs in a safety study.

• Radiation Oncology Journal
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• 제16권4호
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• pp.425-431
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• 1998

목적 : 초기 비소세포 폐암환자의 치료시 늑막하병변이 있는 경우에 치료후 결과에 어떤 영향을 주는지를 분석하고, 이 결과를 토대로 향후 치료방침의 결정에 도움을 주기 위해서 본 연구를 하였다. 대상 및 방법 : 1990년 12월부터 1996년 9월까지 동아대학병원에서 절제가능한 비소세포 폐암으로 진단받고 수술을 받은 환자 91명중 제 I병기와 제 II병기환자 66명을 대상으로 후향적 분석을 하였다. 66명중 늑막하병변이 있는 경우는 22명이었으며, 제 I병기(T1N0, T2N0)에서 늑막하병변이 있는 경우는 15명/44명(34.1$\%$)이었으며, 제 II병기(T1N1, T2Nl, T3No)에서 늑막하병변이 있는 경우는 7명/22명(31.8$\%$)이었다. 수술후 보조요법으로서 전신 항암요법은 시행되지 않았고, 방사선치료는 7명에서 시행되었다. 최소 추적관찰기간은 8개월이며 최대추적관찰기간은 84개월이며, 평균 추적관찰 기간은 33.2개월(중앙값; 29.5개월)이었다. 생존율은 Kaplan-Meier법으로 분석하였고, 서로간의 성적비교는 log-lank test를 이용하였다. 결과 : 전체환자의 3년 생존율은 69.5$\%$였다. 전체환자에서 늑막하병변이 있는 경우와 없는 경우의 3년 생존율은 각각 35.5$\%$와 84.6$\%$였으며, 통계학적으로 의미있는 차이를 보였다(p=0.0017). 제 I병기에서 늑막하병변이 있는 경우와 없는 경우의 3년 생존율은 각각 33.1$\%$와 92.3$\%$였으며, 통계학적으로 의미있는 차이를 보였다(p=0.001). 제 II병기에서 늑막하병변이 있는 경우와 없는 경우의 3년 생존율은 각각 53.3$\%$와 45.7$\%$였으며, 통계학적으로 차이는 없었다 (p=0.911). 제 I병기환자 44명중 원발종양의 크기가 3cm이상인 경우(T2, 34명)는 늑막하병변이 있는 경우와 없는 경우의 3년 생존율은 각각 27.3$\%$와 90.3$\%$였으며, 통계학적으로 의미있는 차이를 보였다(p=0.009). 국소재발은 늑막하병변이 있는 경우에는 제 I병기에서 2명/15명(13.3$\%$), 제 II병기에서 2명/7명(28.6$\%$)에서 재발하였고, 늑막하병변이 없는 경우에는 제 I병기에서 4명/29명(13.8$\%$), 제 II병기에서 2명/14명(14.3$\%$)에서 국소재발을 보였다. 원격전이는 늑막하병변이 있는 경우에는 제 I병기에서 5명/15명(33.3$\%$), 제 II병기에서 2명/7명(28.6$\%$)에서 원격전이를 보였고, 늑막하병변이 없는 경우에는 제 1병기에서 2명/29명(6.9$\%$), 제 II병기에서 4명/14명(28.6$\%$)에서 원격전이를 보였다. 결론 : 초기 비소세포 폐암환자의 예후에 있어서 늑막하병변의 유무가 중요한 역할을 하는 것으로 생각되며, 특히 임파선 전이가 없는 72병기의 경우 늑막하병변이 있으면 늑막하병변이 없는 경우에 비해 생존율에서 현저한 차이를 보였다.