• Journal of Genetic Medicine
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• 제17권2호
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• pp.83-88
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• 2020

Silver-Russell syndrome (SRS) is a rare genetic disorder characterized by intrauterine growth restriction, poor postnatal growth, relative macrocephaly, a triangular face, body asymmetry, and feeding difficulties. It is primarily diagnosed according to a clinical scoring system; however, the clinical diagnosis is confirmed with molecular testing, and the disease is stratified into the specific molecular subtypes. SRS is a genetically heterogeneous condition. The major molecular changes are hypomethylation of imprinting control region 1 in 11p15.5 and maternal uniparental disomy of chromosome 7 (UPD(7)mat). Therefore, first-line molecular testing should include methylation-specific approaches for these regions. Here, we report an extremely low birth weight (ELBW) infant with intrauterine growth retardation, postnatal growth retardation, and dysmorphic facial appearance-characteristics consistent with the clinical diagnostic criteria of SRS. Methylation-specific molecular genetic analysis revealed UPD(7)mat, while the loss of heterozygosity was not detected on chromosomal microarray analysis. We present a case of SRS with suspected uniparental heterodisomy of chromosome 7 in an ELBW infant.

• 한국추진공학회지
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• 제16권2호
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• pp.25-33
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• 2012

유전알고리즘을 사용하여 액체로켓엔진의 연소실 압력과 노즐 확장비, O/F 비 등 주요 설계변수를 최적화하였다. 대상엔진은 LO2/RP-1을 추진제로 사용하는 개방형 가스발생기 사이클을 대상으로 하였다. 연소실의 물성치는 CEA2를 이용하였으며, 무게 산출은 참고문헌을 바탕으로 모델링 하였다. 최적 설계의 목적함수는 비추력과 추력중량비를 다중목표로 설정하여 가중치 방법을 사용하였다. 유전알고리즘을 최적화 과정을 거친 결과 비추력은 최대 4%, 추력중량비는 최대 23% 정도 증가하였다. 또한 다양한 추력에 대해서 Pareto frontier line을 얻었다.

• 동아시아식생활학회지
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• 제16권6호
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• pp.646-654
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• 2006

This study was designed to examine body shape control and its related factors, including BMI(body mass index), desire for weight control, satisfaction with body shape, dissatisfaction with specific parts of body shape, starting period of concern about body shape, as well as experience, method, result, counsel, effort, expense and knowledge of body shape control. The survey was completed by 180 female university students in Gyeongsanbukdo through a self-administered questionnaire during September and October of 2006. The subjects were assigned to one of three groups based on self-estimated figure: 47.8% of the students estimated their figure as 'normal', while 38.3% of the students estimated themselves as 'thin' and 13.9% of the students as 'fat'. The results were as fellows. The mean age of the subjects was $19.45{\pm}1.67$ with a height and weight of $161.15{\pm}4.99cm$ and $52.63{\pm}10.78\;kg$, respectively. Their self-estimated figure was significantly related to BMI, desire for weight control, satisfaction, dissatisfaction with a specific part, and experience, counsel and effort in body shape control. This research suggests that students need to know how to properly control body shape in health and beauty.

• 한국추진공학회:학술대회논문집
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• 한국추진공학회 2011년도 제37회 추계학술대회논문집
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• pp.127-134
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• 2011

유전알고리즘을 사용하여 액체로켓엔진의 연소실 압력과 노즐 확장비, O/F 비 등 주요 설계변수를 최적화하였다. 대상엔진은 LO2/RP-1을 추진제로 사용하는 개방형 가스발생기 사이클을 대상으로 하였다. 연소실의 물성치는 CEA2를 이용하였으며, 무게 산출은 참고문헌을 바탕으로 모델링 하였다. 최적설계의 목적함수는 비추력과 추력중량비를 다중목표로 설정하여 가중치 방법을 사용하였다. 유전알고리즘을 최적화 과정을 거친 결과 비추력은 최대 4%, 추력중량비는 최대 23% 정도 증가하였다. 또한 다양한 추력에 대해서 Pareto frontier line을 얻었다.

• Carbon letters
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• 제10권3호
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• pp.217-220
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• 2009

In this study, porous electrospun carbon fibers were prepared by electrospinning with PAN and $MgCl_2$, as a MgO precursor. MgO was selected as a substrate because of its chemical and thermal stability, no reaction with carbon, and ease of removal after carbonization by dissolving out in acidic solutions. $MgCl_2$ was mixed with polyacrylonitrile (PAN) solution as a precursor of MgO with various weight ratios of $MgCl_2$/PAN. The average diameter of porous electrospun carbon fibers increased from 1.3 to 3 ${\mu}m$, as the $MgCl_2$ to PAN weight ratio increased. During the stabilization step, $MgCl_2$ was hydrolyzed to MgOHCl by heat treatment. At elevated temperature of 823 K for carbonization step, MgOHCl was decomposed to MgO. Specific surface area and pore structure of prepared electrospun carbon fibers were decided by weight ratio of $MgCl_2$/PAN. The amount of hydrogen storage increased with increase of specific surface area and micropore volume of prepared electrospun carbon fibers.

• 한국해양공학회지
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• 제20권2호
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• pp.52-58
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• 2006

The effect of various environmental conditions on the durability of E-glass fiber/vinylester resin composites have been investigated using the tensile test specimen of strand type. It was found that the durability test method performed by the stand type specimen was more convenient and reliable than other conventional test method. The weight gains increased with the immersion time in both water and alkaline solution, and the Weight gains at $50^{\circ}C$. were much bigger than those at $20^{\circ}C$ in both conditions. The tensile strength decreased with the pass of immersion time in all aqueous solution, and the tensile strength at $80^{\circ}C$ in alkaline solution decreased very steeply at beginning of immersion time. The decrement of tensile strength according to the immersion time in various environmental conditions was mainly caused by the degradation of interface and the damage of glass fiber surface.

• 동의생리병리학회지
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• 제31권2호
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• pp.126-137
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• 2017

This study was aimed to develop the instrument of Korean medical pattern Identification and Functional Evaluation for Five Organ. This study followed seven steps, consisted of first composition of research members, second set-up of the aim, third review for advanced research, fourth finding an important index, fifth puting on the weight for index, sixth advice from linguist and last development of draft of questionnaire. Twenty two in and out researchers joined and put the weight on each question. We developed a draft version of questionnaire of Korean medical pattern identification and functional evaluation for five organ. Most questions between pattern identification and functional evaluation of five organ have similar weight, but several ones have difference in order. Generally, specific symptom represented specific location or related with pain have relatively higher weight on pattern identification, and weakness question gained weight on functional evaluation. We develop the questionnaire of Korean medical pattern identification and functional evaluation for five organ. Following study, which will evaluate the reliability and validity, is needed.

• Animal Bioscience
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• 제36권7호
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• pp.1010-1021
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• 2023

Objective: Growth performance and growth-related traits have a crucial role in livestock due to their influence on productivity. This genome-wide association study (GWAS) in Pakistani dromedary camels was conducted to identify single nucleotide polymorphisms (SNPs) associated with growth at specific camel ages, and for selected SNPs, to investigate in detail how their effects change with increasing camel age. This is the first GWAS conducted on dromedary camels in this region. Methods: Two Pakistani breeds, Marecha and Lassi, were selected for this study. A genotyping-by-sequencing method was used, and a total of 65,644 SNPs were identified. For GWAS, weight records data with several body weight traits, namely, birthweight, weaning weight, and weights of camels at 1, 2, 4, and 6 years of age were analysed by using model-based growth curve analysis. Age-specific weight data were analysed with a linear mixed model that included fixed effects of SNP genotype as well as sex. Results: Based on the q-value method for false discovery control, for Marecha camels, five SNPs at q<0.01 and 96 at q<0.05 were significantly associated with the weight traits considered, while three (q<0.01) and seven (q<0.05) SNP associations were identified for Lassi camels. Several candidate genes harbouring these SNP were discovered. Conclusion: These results will help to better understand the genetic architecture of growth including how these genes are expressed at different phases of their life. This will serve to lay the foundations for applied breeding programs of camels by allowing the genetic selection of superior animals.

• 한국수산과학회지
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• 제43권3호
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• pp.217-222
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• 2010

Two 15-week feeding trials were conducted to investigate how the rate and frequency of feeding affected the winter growth of olive flounder ($13^{\circ}C$). In the first experiment, triplicate groups of fish (initial mean weight $117{\pm}6.0$ g) were fed extruded pellets twice a day at feeding rates of 0.1, 0.25, 0.4, 0.55, and 0.57% (satiation) body weight per day (BW/d). The weight gain, specific growth rate, and feed efficiency increased significantly (P<0.05) with the feeding rates from 0.1 to 0.55% BW/d, but no significant differences in these parameters were found for fish fed diets of 0.55% BW/d and satiation. The moisture and ash contents of whole body of fish tended to decrease as the feeding rate increased, but the opposite trend was found for crude lipid content. In the second experiment, triplicate groups of fish (initial mean weight $117{\pm}6.3$ g) were fed extruded pellets to apparent satiation at the three different feeding frequencies: one meal 2 days, one meal a day and two meals a day. The weight gain and specific growth rate of fish fed one meal 2 days were significantly (P<0.05) lower than those of fish fed one or two meals a day, whereas no significant differences in the weight gain and specific growth rate were found between fish fed one and those fed two meals a day. Feed efficiency and condition factor were not significantly affected by feeding frequency. Based on these results, a feeding rate of 0.3% BW/d is recommended as maintenance feeding level, and the optimum feeding frequency is one meal a day with satiation feeding for the growth of olive flounder (117-147 g) during winter ($13^{\circ}C$).

• 한국보건간호학회지
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• 제34권2호
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• pp.289-300
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• 2020

Purpose: This study aimed to identify gender differences associated with weight related teasing by parents, and development of anti-fat attitudes among Korean children aged 5 to 7 years. Methods: This study used a descriptive cross-sectional design. Questionnaire interviews were conducted by enrolling 222 healthy children having normal development and living with their parents in South Korea. Results: Results showed gender and parental weight-related teasing was significantly associated with anti-fat attitudes among children. Significance of the association between parental weight-related teasing and anti-fat attitudes among kindergarten children differed according to the child's gender. Among girls, the higher level of parental weight-related teasing was associated with greater anti-fat attitude. However, parental weight-related teasing was not associated with increased anti-fat attitude among boys. Conclusion: Considering our study results, we recommend developing programs aimed towards decreasing teasing in the family environment, such as changing the gender-specific weight norms to prevent anti-fat attitudes in Korean girls.