• Korean Journal of Acupuncture
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• v.22 no.3
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• pp.53-61
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• 2005

Objectives : This study was designed to investigate the effect of thermal change on face, acupuncturing Yon-gok (KI2). The room temperature adjust $26^{\circ}C$ making use of air-conditioner. Methods : A Clinical study was done on 20 males and females who didn't have any disease. We used IR-5000 to observe the effects of acupuncture at face temperature. Results : Acupuncturing Yon-gok(KI2), the special region on face falls the temperature (n=20) from Avg.=$28.1400{\pm}0.2603^{\circ}C$ to Avg.=$27.4910{\pm}0.2539^{\circ}C$ the special region on chest falls the temperature (n=20) from Avg.=$26.9450{\pm}0.2591^{\circ}C$ to Avg.=$26.8690{\pm}0.2519^{\circ}C$ These effects result at the stimulating 'Hwa' point, one of five-shu-point one in the meridian, Yon-gok (KI2) is one of 'Hwa'. the stimulating 'Hwa' is able to cure fever, headache, and pains. and it has ablility of controlling body temperature, specially, upper region of whole human body. Conclusions : In conclusion. Acupuncturing Yon-gok (KI2) falls the temperature of region on face, Compared with the temperature of region on chest.

• Journal of Ginseng Research
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• v.44 no.3
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• pp.475-482
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• 2020

Background: Active natural ingredients, especially small molecules, have recently received wide attention as modifiers used to treat neurodegenerative disease by promoting neurogenic regeneration of neural stem cell (NSC) in situ. 20(S)-protopanaxadiol (PPD), one of the bioactive ingredients in ginseng, possesses neuroprotective properties. However, the effect of PPD on NSC proliferation and differentiation and its mechanism of action are incompletely understood. Methods: In this study, we investigated the impact of PPD on NSC proliferation and neuronal lineage differentiation through activation of the Wnt/glycogen synthase kinase (GSK)-3β/β-catenin pathway. NSC migration and proliferation were investigated by neurosphere assay, Cell Counting Kit-8 assay, and EdU assay. NSC differentiation was analyzed by Western blot and immunofluorescence staining. Involvement of the Wnt/GSK3β/β-catenin pathway was examined by molecular simulation and Western blot and verified using gene transfection. Results: PPD significantly promoted neural migration and induced a significant increase in NSC proliferation in a time- and dose-dependent manner. Furthermore, a remarkable increase in anti-microtubule-associated protein 2 expression and decrease in nestin protein expression were induced by PPD. During the differentiation process, PPD targeted and stimulated the phosphorylation of GSK-3β at Ser9 and the active forms of β-catenin, resulting in activation of the Wnt/GSK-3β/β-catenin pathway. Transfection of NSCs with a constitutively active GSK-3β mutant at S9A significantly hampered the proliferation and neural differentiation mediated by PPD. Conclusion: PPD promotes NSC proliferation and neural differentiation in vitro via activation of the Wnt/GSK-3β/β-catenin pathway by targeting GSK-3β, potentially having great significance for the treatment of neurodegenerative diseases.

• Journal of Korean Society for Atmospheric Environment
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• v.15 no.2
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• pp.211-217
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• 1999

Data on ambient levels of $SO_2$, $NO_x$, and their emissions in Northeast Asia with special emphasis on China are collected and discussed. Also, study results on long-range transport of air pollutants in the region were briefly discussed. It was found that emissions of air pollutants in China are dominant over the region.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.54 no.2
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• pp.164-172
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• 2018

This study aimed to analyze the profitability and economic feasibility of hairtail trolling line gear that was developed for the last 3 years (2015-2017). The new fishing gear technology development was accomplished to solve the current problem of fishermen shortage in hairtail targeting fisheries in Jeju region. Results indicated that the profitability of developed hairtail trolling line fishery was estimated to be 36.1 % which would be higher than that of other hairtail targeting fisheries in Jeju region. In addition, as an economic feasibility, the net present value and the internal rate of return of a 20-year cash inflow and outflow were evaluated to be 400.2 million won and 66.9 %, respectively. However, sensitivity analyses of main variables showed that the profitability and economic feasibility would be vulnerable to catch amount and market condition changes.

• Journal of Acupuncture Research
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• v.26 no.2
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• pp.41-48
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• 2009

Objectives : The conventional direct and indirect moxibustion therapies for prostate treatment could not been applied to the acupuncture point of $CV_1$(Conception Vessel Meridian 1, 會陰) because of its boring body region. The position of $CV_1$(會陰) is the back side of hard part between the anus and the genital organ. The conventional moxibustion methods have many troubles in operating to the acupuncture point of $CV_1$(會陰). In order to get rid of these problems, we have suggested the special heat generating terminal especially for prostate. The features of the special heat generating terminal for prostate are the low temperature infrared heater and the adhesive moxa-pad. These features are no burnt, no fiery and especially suitable for the point of $CV_1$(會陰). Methods: The heat generating terminal which is a part of the moxa-extract moxibustion cauterizer is composed of a PTC(Positive Temperature Coefficients) ceramic heater and the adhesive moxa-pad We had got the experimental demonstrations by the stimulating the acupuncture points which are $CV_1$(會陰), $BL_{28}$(Bladder Meridian 28, 膀胱兪), and $CV_3$(Conception Vessel Meridian 3, 中極) with the special heat generating terminal for the prostatitis and the benign prosthetic hypertrophy. And the stimulation level was 43$^{\circ}C$ infrared heat for one hour. The type of thermography is IRIS-5000. Results : With one subject suffering the prostatitis and another subject suffering the benign prosthetic hypertrophy, we cauterized the acupuncture points $CV_1$(會陰), $BL_{28}$(膀胱兪) and $CV_3$(中極) with the special heat generating terminal for prostate. We measured the temperature variations by the thermography before and after stimulations. Finally we estimated the tendency of temperature decreasing in the region of post-stroke urinary symptoms and the improvement of nocturnal enuresis after the stimulations. Conclusions : We suggest that the special heat generating terminal of moxa-extract moxibustion cauterizer proposed herein is effective for the treatment of prostate by NIH-CPSI and IPSS.

• Journal of The Korean Astronomical Society
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• v.29 no.spc1
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• pp.77-78
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• 1996

We perfom a large project for complex study of Blue Compact Galaxies (BCGs) with strong star formation, which includes optical spectroscopy, BVR CCD photometry and HI 21 cm radio survey. The most interesting galaxies are studied also with HST and VLA. In the frame of this project we began the study of H$\alpha$ morphology of BCGs with 6-m telescope. We present and discuss here the results for the first 6 galaxies. We found the noticeable variety of forms for H$\alpha$ morphology comparing to broad band images: from very compact HII region in very center of stellar body (Mark 996, possible dwarf post-merger, old galaxy experiencing strong star formation burst), to very extended gas emission encompassing the whole area traced by stars (SBS 0335-052, the most probable young galaxy in formation).

• Proceedings of the Korea Concrete Institute Conference
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• 2002.05a
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• pp.291-296
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• 2002

In order to apply precast decks to the continuous composite bridges, several experiments and analytical studies were performed. For the continuous composite bridges, special attention should be paid to the transverse joints in negative moment region. Judging from the results, combination of longitudinal internal prestressing tendon and the external tendon can be effectively used for the prevention of cracking in the negative moment region of precast decks.

• Journal of the Speleological Society of Korea
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• no.85
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• pp.38-40
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• 2008

With regard to Jeju Special Self-governing Province's natural-spa tourist spot development project, this paper has investigated the natural environment of Sehwa-Songdang Lave Region. According to this study, the cave consists of many small caverns with poor cave formations. Due to unfavorable climate conditions in the cave, in addition, hydrological environment is also very poor. In terms of vegetation, the cave shows the general vegetation environment of Jeju.

• Journal of the Korean Society of Earth Science Education
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• v.8 no.3
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• pp.259-266
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• 2015

This study aims to analyze a selective examination for the gifted and talented from a domain-general and special standpoint. For this, we analyzed gifted and talented test results carried out by Gifted and Talented Education institute affiliated with the university of Education located in the central region of South Korea. This test consisted of three sections which are giftedness in the first round, academic aptitude in the second round and interview in the last round. I conducted the analysis of variance of the giftedness test result to the gifted and talented group in each subject from the domain-general point of view. As a result, the each group was not significant. This means that the gifted and talented in each subject has giftedness from the domain-general viewpoint. Secondly, I implemented the analysis of correlation among three test such as giftedness, academic aptitude and interview conducted during the selective process for the gifted and talented. The result was that they had a low or no correlations between them and were not significant. This demonstrated that each test checked a different area. That is, we came to realize that the first, second and third test evaluates a different area and in particular, with the result that the first and second test had a low or no correlations between both of them we realized that they evaluated a different area from a domain-special standpoint. The purpose of this study is meaningful to investigate in terms of how the selective test for the gifted and talented is conducted from a domain-general and special standpoint as a recent study viewpoint about the gifted and talented along with creativity. It is too limited to generalize this result because this test was sampled by one region but, this study indicates that we should take a domain-general and special standpoint into account when it comes to selection for the gifted and talented.

• Journal of Environmental Science International
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• v.20 no.7
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• pp.857-872
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• 2011

The variation of groundwater level in Jeju Island is analyzed with the data of precipitation observed from 48 monitoring post and groundwater level observed from 84 monitoring wells during 2001 to 2009. The groundwater level rises in summer and falls in winter. The rise of groundwater level by precipitation is fast and small in the eastern region and slow and large in the western region. However, the speed of fall during the period of no rain is slower in the eastern region than in the western region. It tells that permeability is greater in the eastern region than in the western region. In this paper, we set up the base level of groundwater and calculate recharge volume between the base level and groundwater surface. During the period, the average recharge volume was $9.83{\times}10^9m^3$ and the maximum recharge volume was $2.667{\times}10^{10}m^3$ after the typhoon Nari. With these volume and the recharge masses obtained by applying the recharge ratio of 46.1%, estimated by Jeju Province (2003), the porous ratio over the whole Jeju Island is 16.8% in average and 4.6% in the case of maximum recharge volume just after typhoon Nari. A large difference in the two ratios is because that it takes time for groundwater permeated through the ground just after rain fall to fill up the empty porous part. Although the porous ratios over the whole Jeju Island obtained in this way has a large error, they give us the advantage to roughly estimate the amount of recharged groundwater mass directly from observing the groundwater level.