• 제목/요약/키워드: Soft-sensing

검색결과 84건 처리시간 0.022초

Dual-Toehold-Probe-Mediated Exonuclease-III-Assisted Signal Recycles Integrated with CHA for Detection of mecA Gene Using a Personal Glucose Meter in Skin and Soft Tissue Infection

  • Jiaguang Su;Wenjun Zheng
    • Journal of Microbiology and Biotechnology
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    • 제33권12호
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    • pp.1692-1697
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    • 2023
  • Staphylococcus aureus integrated with mecA gene, which codes for penicillin-binding protein 2a, is resistant to all penicillins and other beta-lactam antibiotics, resulting in poor treatment expectations in skin and soft tissue infections. The development of a simple, sensitive and portable biosensor for mecA gene analysis in S. aureus is urgently needed. Herein, we propose a dual-toehold-probe (sensing probe)-mediated exonuclease-III (Exo-III)-assisted signal recycling for portable detection of the mecA gene in S. aureus. When the target mecA gene is present, it hybridizes with the sensing probe, initiating Exo III-assisted dual signal recycles, which in turn release numerous "3" sequences. The released "3" sequences initiate catalytic hairpin amplification, resulting in the fixation of a sucrase-labeled H2 probe on the surface of magnetic beads (MBs). After magnet-based enrichment of an MB-H1-H2-sucrase complex and removal of a liquid supernatant containing free sucrase, the complex is then used to catalyze sucrose to glucose, which can be quantitatively detected by a personal glucose meter. With a limit of detection of 4.36 fM for mecA gene, the developed strategy exhibits high sensitivity. In addition, good selectivity and anti-interference capability were also attained with this method, making it promising for antibiotic tolerance analysis at the point-of-care.

자성 액추에이터 기반의 소프트 로봇 (Soft Robots Based on Magnetic Actuator)

  • 노규령;최문기
    • 한국전기전자재료학회논문지
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    • 제34권6호
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    • pp.401-415
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    • 2021
  • Soft robots are promising devices for applications in drug delivery, sensing, and manufacturing. Traditional hard robotics are manufactured with rigid materials and their degrees of motion are constrained by the orientation of the joints. In contrast to rigid counterpart, soft robotics, employing soft and stretchable materials that easily deforms in shape, can realize complex motions (i.e., locomotion, swimming, and grappling) with a simple structure, and easily adapt to dynamic environment. Among them, the magnetic actuators exhibit unique characteristics such as rapid and accurate motion control, biocompatibility, and facile remote controllability, which make them promising candidates for the next-generation soft robots. Especially, the magnetic actuators instantly response to the stimuli, and show no-hysteresis during the recovery process, essential for continuous motion control. Here, we present the state-of-the-art fabrication process of magnetically controllable nano-/micro-composites, magnetically aligning process of the composites, and 1-dimensional/multi-dimensional multimodal motion control for the nextgeneration soft actuators.

지능센서의 센싱능력 평가를 위한 평가기법 개발 (Development Estimation Method to Estimate Sensing Ability of Smart Sensors)

  • 황성연;마사히코 무루조노;김영문;홍동표
    • 한국공작기계학회논문집
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    • 제15권2호
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    • pp.99-106
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    • 2006
  • In this paper, the new method that estimates a sensing ability of smart sensor will be proposed. A study is estimation method that evaluates sensing ability about smart sensor respectively. According to acceleration(g) and displacement changing, we estimated sensing ability of smart sensor using SAI(Sensing Ability Index) method respectively. Smart sensors was made fer experiment. The types of smart sensor are two types(hard and soft smart sensor). Smart sensors developed for recognition of material. Experiment and analysis are executed for estimate the SAI method. In develop a smart sensor, the SAI method will be useful for finding optical design condition of smart sensor that can sense a material. And then dynamic characteristics of smart sensors(frequency changing, acceleration changing, critical point, etc.) are evaluated respectively through new method(SAI) that use the power spectrum density. Dynamic characteristic of sensor is evaluated with SAI method relatively. We can use the SAI for finding critical point of smart sensor, too.

자성 분말 기반 소프트 자성 액츄에이터 및 센서 연구 동향 (Recent Advances in Soft Magnetic Actuators and Sensors using Magnetic Particles)

  • 송현서;이하준;김정효;김지윤
    • 한국분말재료학회지
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    • 제28권6호
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    • pp.509-517
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    • 2021
  • Smart materials capable of changing their characteristics in response to stimuli such as light, heat, pH, and electric and magnetic fields are promising for application to flexible electronics, soft robotics, and biomedicine. Compared with conventional rigid materials, these materials are typically composed of soft materials that improve the biocompatibility and allow for large and dynamic deformations in response to external environmental stimuli. Among them, smart magnetic materials are attracting immense attention owing to their fast response, remote actuation, and wide penetration range under various conditions. In this review, we report the material design and fabrication of smart magnetic materials. Furthermore, we focus on recent advances in their typical applications, namely, soft magnetic actuators, sensors for self-assembly, object manipulation, shape transformation, multimodal robot actuation, and tactile sensing.

Unlimited Cooperative Sensing with Energy Detection for Cognitive Radio

  • Bae, Sunghwan;Kim, Hongseok
    • Journal of Communications and Networks
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    • 제16권2호
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    • pp.172-182
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    • 2014
  • In this paper, we investigate the fundamental performance limits of the cooperative sensing using energy detection by considering the unlimited number of sensing nodes. Although a lot of cognitive radio research so far proposed various uses of energy detection because of its simplicity, the performance limits of energy detection have not been studied when a large number of sensing nodes exist. First, we show that when the sensing nodes see the independent and identically distributed channel conditions, then as the number of sensing nodes N goes to infinity, the OR rule of hard decision achieves zero of false alarm Pf for any given target probability of detection $\bar{P_d}$ irrespective of the non-zero received primary user signal to noise ratio ${\gamma}$. Second, we show that under the same condition, when the AND rule of hard decision is used, there exists a lower bound of $P_f$. Interestingly, however, for given $\bar{P_d}$, $P_f$ goes to 1 as N goes to infinity. Third, we show that when the soft decision is used, there exists a way of achieving 100% utilization of secondary user, i.e., the sensing time overhead ratio goes to zero so does $P_f$.We verify our analyses by performing extensive simulations of the proposed unlimited cooperative sensing. Finally, we suggest a way of incorporating the unlimited cooperative sensing into a practical cellular system such as long term evolutionadvanced by exploiting the existing frame structure of absolute blank subframe to implement the in-band sensing.

고효율 CMOS PWM DC-DC 벅 컨버터 (High-Efficiency CMOS PWM DC-DC Buck Converter)

  • 김승문;손상준;황인호;유성목;유종근
    • 한국정보통신학회:학술대회논문집
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    • 한국해양정보통신학회 2011년도 추계학술대회
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    • pp.398-401
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    • 2011
  • 본 논문에서는 고효율의 CMOS PWM DC-DC 벅 변환기를 설계하였다. 설계된 CMOS PWM DC-DC 벅 변환기는 입력전압(3.4-3.9V)로부터 일정한 출력전압(1-2.8V)을 생성한다. Inductor-based 방식을 택하였고, 제어 대상은 전류이며, Pulse Width Modulation(PWM) 모드로 동작한다. 회로 구성은 Power Switch, Pulse Width Generation, Buffer, Zero Current Sensing, Current Sensing Circuit, Clock & Ramp generation, V-I Converter, Soft Start, Compensator, Modulator 등 이다. 제안된 CMOS PWM DC-DC 벅 컨버터는 Switching Frequency가 약 1MHz이고, 부하 전류가 약 40mA이상부터 CCM동작을 하며 100mA일 때 98.71%의 최대 효율을 갖는다. 또한, 출력전압 리플은 0.98mV이다(입력전압 3.5V, 출력전압 2.5V 기준). 제안된 회로의 검증을 위해 CMOS $0.18{\mu}m$ 공정을 이용하여 시뮬레이션을 수행하였다.

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Ultra Low Field Sensor Using GMI Effect in NiFe/Cu Wires

  • Kollu, Pratap;Kim, Doung-Young;Kim, Cheol-Gi
    • Journal of Magnetics
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    • 제12권1호
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    • pp.35-39
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    • 2007
  • A highly sensitive magnetic sensor using the Giant MagnetoImpedance effect has been developed. The sensor performance is studied and estimated. The sensor circuitry consists of a square wave generator (driving source), a sensing element in a form of composite wire of a 25 $\mu$m copper core electrodeposited with a thin layer of soft magnetic material ($Ni_{80}Fe_{20}$), and two amplifier stages for improving the gain, switching mechanism, scaler circuit, an AC power source driving the permeability of the magnetic coating layer of the sensing element into a dynamic state, and a signal pickup LC circuit formed by a pickup coil and an capacitor. Experimental studies on sensor have been carried out to investigate the key parameters in relation to the sensor sensitivity and resolution. The results showed that for high sensitivity and resolution, the frequency and magnitude of the ac driving current through the sensing element each has an optimum value, the resonance frequency of the signal pickup LC circuit should be equal to or twice as the driving frequency on the sensing element, and the anisotropy of the magnetic coating layer of the sensing wire element should be longitudinal.

Artificial muscles: Non-Stoichiometry Nature, Sensing and Actuating Properties and Tactile Sensibility

  • Otero T.F.;Lopez-Cascales J.J.;Vazquez-Arenas G.
    • KIEE International Transaction on Electrical Machinery and Energy Conversion Systems
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    • 제5B권2호
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    • pp.118-122
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    • 2005
  • Electro-chemo-mechanical devices or artificial muscles based on conducting polymers (CP) are presented as bilayers, CP/adhesive polymer, or as triple layers, CP/adhesive polymer/CP. Those soft and wet materials, working in aqueous solutions of a salt, mimic the composition of most organs from animals. Under electrochemical control, so working as new electrical machines, they produce continuous, reverse and elegant bending movements, mimicking those produce by animal muscles. By means of the current a perfect controls of the movement rate is attained giving soft and continuous movements. Muscles able to sense the chemical and mechanical conditions of work or muscle having tactile sense, as will be presented here, are being developed. All of them are founded on the non-stoichiometric nature of the soft and wet materials.

Current Control Scheme of High Speed SRM Using Low Resolution Encoder

  • Khoi, Huynh Khac Minh;Ahn, Jin-Woo;Lee, Dong-Hee
    • Journal of Power Electronics
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    • 제11권4호
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    • pp.520-526
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    • 2011
  • This paper presents a balanced soft-chopping circuit and a modified PI controller for a high speed 4/2 Switched Reluctance Motor (SRM) with a 16 pulse per revolution encoder. The proposed balanced soft-chopping circuit can supply double the switching frequency in the fixed switching frequency of power devices to reduce current ripple. The modified PI controller uses maximum voltage, back-emf voltage and PI control modes to overcome the over-shoot current due to the time delay effect of current sensing. The maximum voltage mode can supply a fast excitation current with consideration of the hardware time delay. Then the back-emf voltage mode can suppress the current over-shoot with consideration of the feedback signal delay. Finally, the PI control mode can adjust the phase current to a desired value with a fast switching frequency due to the proposed balanced soft-chopping technology.

마이크로프로세서를 사용한 고효율 인버터 안정기에 관한 연구 (A Study on Hight Efficiency Inverter Ballast using Microprocessor)

  • 정재륜
    • 한국조명전기설비학회지:조명전기설비
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    • 제13권2호
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    • pp.220-220
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    • 1999
  • This paper describes the high efficiency inverter ballast circuit using very cheap microprocessor, which has been developed by the author. A variety of soft-switching techniques have been proposed to reduce the switching losses and EMI problems that occur with higher switching frequencies in switched inverter ballast. The inverter ballast circuit, which employs a temperature sensing circuits has been also proposed to improve starting performance of the fluorescent lamps. That is, the inverter ballast circuit, which employs a soft-starting circuit and soft-switching techniques to implement the power factor correction and to mitigate of power-loss and increase a life time of the fluorescent lamps, has become an attractive performance for ballasting the fluorescent lamps. In this paper, the operation and the control of the inverter ballast are described in detail and experimental results are presented. As the experimental results, when environment temperature is at -40℃, the inverter ballast circuit has low THD(4.8%) of the input current and large power factor(98%) of the lamp current. The proposed improved ballast circuit appears to be a good performance for ballasting fluorescent lamps.