• Journal of Periodontal and Implant Science
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• v.43 no.4
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• pp.191-197
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• 2013

Purpose: Nitric oxide (NO) is a short-lived bioactive molecule that is known to play an important role in the pathogenesis of periodontal disease. In the current study, we investigated the effect of the flavonoid quercetin on the production of NO in murine macrophages activated with lipopolysaccharide (LPS) from Prevotella intermedia, a pathogen related to inflammatory periodontal disease, and tried to elucidate the underlying mechanisms of action. Methods: LPS was isolated from P. intermedia ATCC 25611 cells by the standard hot phenol-water method. The concentration of NO in cell culture supernatants was determined by measuring the accumulation of nitrite. Inducible NO synthase (iNOS) and heme oxygenase-1 (HO-1) protein expression, phosphorylation of c-Jun N-terminal kinase (JNK) and p38, inhibitory ${\kappa}B$ $(I{\kappa}B)-{\alpha}$ degradation, and signal transducer and activator of transcription 1 (STAT1) phosphorylation were analyzed via immunoblotting. Results: Quercetin significantly attenuated iNOS-derived NO production in RAW246.7 cells activated by P. intermedia LPS. In addition, quercetin induced HO-1 protein expression in cells activated with P. intermedia LPS. Tin protoporphyrin IX (SnPP), a competitive inhibitor of HO-1, abolished the inhibitory effect of quercetin on LPS-induced NO production. Quercetin did not affect the phosphorylation of JNK and p38 induced by P. intermedia LPS. The degradation of $I{\kappa}B-{\alpha}$ induced by P. intermedia LPS was inhibited when the cells were treated with quercetin. Quercetin also inhibited LPS-induced STAT1 signaling. Conclusions: Quercetin significantly inhibits iNOS-derived NO production in murine macrophages activated by P. intermedia LPS via anti-inflammatory HO-1 induction and inhibition of the nuclear factor-${\kappa}B$ and STAT1 signaling pathways. Our study suggests that quercetin may contribute to the modulation of host-destructive responses mediated by NO and appears to have potential as a novel therapeutic agent for treating inflammatory periodontal disease.

• Journal of Digital Contents Society
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• v.15 no.5
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• pp.587-594
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• 2014

Owing to supply of smart phones and the diffusion of SNS, the number of peoples who are living, linked with us, is incomparably more than in the past. The continuous communication is essential in maintaining good relationship, so peoples have no choice but to seek for most efficient communication method in order to maintain good relationship. This thesis intended to advise how to construct next generation immersive multi-media system, using augmented reality and MPEG-V that have come to the fore recently. In addition, the SNS platform service of new type was suggested in this thesis, in connection with the pairing service. Now, we can create a town in a specific space like the real world, if we utilize the augmented reality that became possible by SNS service and we can talk and exchange informations in that space. This system would provide various services peoples wish to have, interlocking experiences through five senses like sense of vision, sense of hearing, sense of touch and etc..

• Journal of Digital Convergence
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• v.13 no.9
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• pp.201-208
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• 2015

With services such as SNS and facebook, Big Data popularize the use of small size such as micro blogs are increasing. However, the problem of accuracy and computational cost of the search result of big data of a small size is unresolved. In this paper, we propose a subnet selection techniques based probability to improve the browsing speed of the small size of the text information from big data environments, such as micro-blogs. The proposed method is to configure the subnets to give to the attribute information of the data increased the probability data search speed. In addition, the proposed method improves the accessibility of the data by processing a pair of the connection information between the probability of the data constituting the subnet to easily access the distributed data. Experimental results showed the proposed method is 6.8% higher detection rates than CELF algorithm, the average processing time was reduced by 8.2%.

• Journal of Digital Convergence
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• v.12 no.10
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• pp.211-222
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• 2014

This study investigates the antecedents of continuance intention of mobile SNS. In addition, it also explores the mediating role of perceived value in the relationship between the antecedent and continuance intention. This study posits that a social influence, perceived usefulness, privacy concern, and a perceived effort of use are major factors to influence continuance intention of SNS. By using a PLS analysis, this finding suggests that consumers' perception of the value of SNS which is previously overlooked, is a primary determinant of continuance intention, and the other exploratory factors are mediated through perceived value in cognitive aspect. This research aims to examine consumer's SNS continuance intention in terms of consumer's perspective, not just from the technology user perspective. Therefore, this research provides a useful guideline for marketing managers on how to manage Mobile SNS properly.

• Journal of Digital Contents Society
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• v.19 no.2
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• pp.385-392
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• 2018

Iksan is one of medium city in Jellabukdo, South Korea. It has a favorable natural environment for the specialization potential of natural industries and development projects. In addition, it has various historical and cultural resources including Mireuksajji, and KTX Honam line which has been opened for a representative feature as transport city. However, it faces week connection with neighboring cities and large scale of development in neighboring areas, especially in Jeonju and Gunsan. In this paper, we try to classify the urban image assets of Iksan as 'Iksan Station' and 'ktx' on keywords and analyze the possibility of being a center of transportation and logistics through big data analysis extracted from SNS and website. In comparison with Gwangju Songjeong, KTX Honam line station, which has been developed with similar regional characteristics, it is aimed to establish the basis of improvement and establishment of urban image of Iksan city in the future.

• Corrosion Science and Technology
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• v.13 no.1
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• pp.15-19
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• 2014

Recently, anti-fouling paints which does not include the poison components such as tin(Sn), copper(Cu) have been increasingly developed in order to inhibit the environmental contamination of the sea water. Moreover, the wear ratios of these anti-fouling paints are very important problem to prolong their life time in economical point of view. In this study, five types of anti-fouling paints as self polishing type were investigated on the relationship between their polarization characteristics and wear ratios. It was verified that there was apparently a good relationship between the wear ratio and polarization characteristics, for example, the wear ratio increased with increasing the impedance ratio, and increased or decreased with the corrosion potential shifting in the negative or positive direction respectively. In addition, the wear ratio decreased with decreasing the corrosion current density. Consequently, it is suggested that we can qualitatively expect the wear ratio by only measuring the polarization characteristics. Therefore, before the examination of the wear ratio was actually carried out in the field, the evaluation of polarization property in the laboratory may give a available reference data for their developments.

• Membrane Journal
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• v.19 no.4
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• pp.333-340
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• 2009

This paper is designed with the purpose of improving the efficiency of the sulfonic acid ion exchange membranes by radiation induced graft polymerization. It has been shown that the porous hollow fiber membranes could cause permeability blocking between pores and ion exchanged graft chains. Addition of crosslinker such as N-ethylene glycol dimethacrylate will permit to increase the permeation flux. In this research, the ethylene glycol dimethacrylate (EDMA) and diethylene glycol dimethacrylate (DDMA) with different length are used as crosslinkers. The ion exchanged cross-linked membrane (EDMA, DDMA) containing sulfonic acid group by radiation induced grafted polymerization are sn died for adsorb metal ions (Pb). It has been shown that adsorbed metal ions ($Pb^{2+}$) for the EDMA and DDMA membranes with the density of sulfonic acid groups, 1.40 mmol/g and 2.14 mmol/g, respectively are 13.82 mg/g, 17.37 mg/g, accordingly.

• Preventive Nutrition and Food Science
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• v.15 no.4
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• pp.275-281
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• 2010

The chemical characteristics of seed oils of Asian ginseng (Panax ginseng C.A. Meyer) at different ages grown in Korea (3, 4 and 5-year old) and China (5-year old), and American ginseng (Panax quinquefoliu L., 5-year old) grown in China were compared. Total fatty acid composition showed a significantly higher oleic acid content in American (87.50%) than in Korean (68.02~69.14%) and Chinese ginseng seed oils (61.19%). At the sn-2 position, the highest oleic acid (81.09%) and lowest linoleic acid (15.77%) were found in American ginseng seed oil. The main triacylglycerol species in ginseng seed oils were triolein (OOO) and 1,2-dioleoyl-3-linoleoyl-glycerol (LOO)/1,3-dioleoyl-2-linoleoyl-glycerol (OLO). In addition, the seed oils possessed an ideal oxidative stability showing 16.55~23.12 hr of induction time by Rancimat test. The results revealed that ginseng seed oil could be developed as a new healthy edible oil, and that the oil's chemical characteristics were strongly associated with the ginseng species and habitats.

• Journal of The Korea Institute of Healthcare Architecture
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• v.23 no.4
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• pp.7-15
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• 2017

Purpose: The Korean government has implemented a Barrier Free Certification System since 2008 to create a secure and convenient environment for the socially disadvantaged. The drastic increase in the number of BF-certification facilities is expected due to the revision of the system and increasing the number of certification institutions. An analysis of individual evaluation items needs to be made for the BF-Certification with public confidence. Method: Korean standard, International Standard(ISO/FDIS 21542, 2011), German Standard(DIN 18040-1, 2010), Austrian Standard(${\ddot{O}}NORM$ B 1600, 2017) and Swiss Standard(Norm SIA 500 / SN 521 500, 2009) were investigated and analyzed. A comprehensive improvement plan is proposed by comparing details of the aforementioned standards and the evaluation items of BF-Certification. Results: Many problems arise in applying existing Barrier-free standards due to changes in population structure, environmental change and the use of powered wheelchairs. International standards are being improved to solve these problems. The korean standards also require improving of the Barrier Free Law and Certification System, which reflect these trends. In korean cases, standards such as the size of the doors (width and height), the Unobstructed Manoeuvring Space and Clear Space at the Latch side of the Door are required to improve standards in accordance with international standards. In addition, the expression of laws and evaluation items of BF-Certification should be clearly defined. And the application of visual contrast standards for the enhancement of perceptions presented in international standards should be considered. Implication: Barrier Free related legal standards and evaluation items of BF-Certification that are used in Korea are required to be revised in consideration of social and environmental changes. Comprehensive improvements should be made through detailed review.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.6
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• pp.254-260
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• 2019

Recently, a self-camera that generates and distributes a large amount of moving images has been rapidly increasing due to the appearance of SNS such as Facebook, Instagram, and Tweet using mobile. In particular, the amount of SNS connections using mobile phones is significantly increasing in terms of usage, number of connections, and usage time. However, the use of a self-recording system using a smartphone by itself is extremely limited not only in terms of usage but also in frequency of use. In addition, the conventional unattended recording system is a very expensive system that automatically records and tracks an object to be photographed using an infrared signal. Therefore, this paper developed a low cost unmanned recording system using mobile phone. The system consists of a commercial mobile camera, a servomotor for moving the camera from side to side, a microcontroller for controlling the motor, and a commercial wireless Bluetooth earset for video audio input. And it is an unmanned automation system using mobile, and anyone can record image by self image tracking.