• Journal of the Korean Society of Marine Environment & Safety
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• v.18 no.4
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• pp.365-370
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• 2012

International Organization for Standardization has recently published ISO 12215-5 which is the small craft-hull construction and scantling. According to ISO 12215-5 AnnexB, the scantling determination can be accomplished by drop test for craft with a length $L_H$ of 2.5m up to 6m and single-skin construction. The current method, however, of visual test has the issue where it is difficult to make an objective evaluation of ship body strength. In this study, in order to develop an evaluation system that can make a quantitative evaluation of the drop test of leisure boats, the domestic/foreign regulations on drop test of leisure boats are analyzed and the drop test evaluation system is designed, and the system applicability is reviewed through 5-meter level aluminum ship, and the issues incurred by the state of the ship and the posture while dropping were checked.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.14 no.9
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• pp.2113-2119
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• 2010

In this paper, the cooperative curriculum between university and company according to the 'Type of IT Business(TIB)' is proposed for an IT manpower cultivation. The cooperative curriculum is established by the core technology from the matching table between 'Type of IT Business(TIB)' and 'Class of IT Techniques(CIT)'. The company participated in the cooperative curriculum gives a guarantee of the job position to the university students who took this cooperative curriculum. For the cooperative curriculum, the agreement is needed between university and company for the establishment and its operation of UCCCC(University and Company Cooperative Curriculum Council) after an exchange of the Memorandum of Understanding(MOU) including the supply-demand of IT manpower, the core technology, and the job conditions. The cooperative curriculum will be useful for employments of small and medium sized companies.

• Journal of Technology Innovation
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• v.17 no.1
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• pp.49-67
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• 2009

As technological capabilities have enhanced, the patterns of innovation activities of latecomer firms changed to post catch-up mode. The purpose of this research is to analyze the post catch-up innovation patterns of technology-intensive small and medium firms of Korea. The innovation patterns can be divided into three types: the technology deepening innovation type, the new technology based innovation type and the architectural innovation type. The characteristics of the technology deepening innovation type are cumulative technological learning and the integration of new generic technology and existing technologies. The characteristics of new technology based type are the acquisition and revelations of new basic knowledges from former incubating organizations such as large firms and universities. The characteristics of the architectural innovation type are the learning of system architecture knowledge from former organization and interactive learning with user firms. These post catch up innovations also have some general characteristics. They effectively exploited the windows of opportunities which are opened in the middle of technological paradigm change.

• Asia pacific journal of information systems
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• v.5 no.1
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• pp.236-257
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• 1995

Not much attention has been paid to the characteristics of successful MIS in small business in Korea. This study compares the characteristics of successful MIS with those of less successful MIS of manufacturing industry in Korea in terms of micro level, macro level, and personal level. The micro level consists of those variables relating to the system development and maintenance while the macro level consists of the environmental variables relating to the information systems. The personal level measures a personal EDP experience. A mail survey was sent to small manufacturing companies to collect the data for the hypothesis tests. And 81 usable questionnaires were returned for data analysis. This study performs the validity of the categorization of variables in terms of three levels. The results shows that this categorization is appropriate but the personal level. As the personal experiences of EDP in Korea used to come up with those of the organization, the variables in the personal level have high correlations with those in the macro level in empirical testing. As the personal level, however, is different dimension from the macro level in theoretical aspect, the level is maintained separately throughout the study. The data were analyzed with MANOVA and two group discriminant analysis. The analyses reveal that the characteristics of successful MIS are different from those of less successful MIS in terms of three levels. And the micro level is more important than the macro level to develop successful MIS. That is because the organizations have relatively few experience in dealing with information systems, they have not developed unique information systems which are adjusted to their organizational characteristics. Those findings seems to be important determinants of success for the MIS in a firm.

• Journal of Digital Convergence
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• v.11 no.3
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• pp.23-31
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• 2013

In Korea, middle and small-sized company takes up an absolute majority of all businesses, and most of them are founded as a limited company. Yet, it is a type of business that fits a company of certain size, and its establishment process is complicated due to various reasons such as investor protection. It is also required to have strict organization structure based on the principle of separation of ownership and management. Accordingly, as the principles may undermine entrepreneur's will to start business, there has been dramatic change in legal system on business establishment and management since 2010. The changes include streamlined process at the foundation stage and digitalization of many regulations on business establishment and operation for more convenience in starting business. Also, new business types for small-sized companies were adopted, and freedom to select business name has been enhanced. The issue of non-par value stock has been allowed, and various types of stock have been adopted for more convenient financing, defense against hostile M&A, and easier business succession.

• The KIPS Transactions:PartA
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• v.10A no.2
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• pp.83-92
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• 2003

RAID 5 is a widely-used technique used to construct disk systems of high reliability and performance. This paper proposes APGOC (Adaptive Parity Group On Cache) organization on cache to solve "small write" problem of RAID 5 especially in OLTP (On-Line Transaction Processing System) environments. In our approach, when user process makes a request for a file to kernel, the information on the read/write characteristics is added to the file data structure of the file system. With this information, data and parity cache can be managed interchangeably through parity fetching. Therefore we can enhance the cache utilization and improve the disk request response time. Our method is analyzed and evaluated with a simulation method. Comparing with previous works, we observed about 6~l3% of performance enhancement.hancement.

• Journal of Convergence Society for SMB
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• v.3 no.1
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• pp.49-55
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• 2013

This study is for preparation a solution develop small suppliers. For this goal survey for the buyers, agents, supplier's situation and difficulties, policy and support systems. And After benchmark the other's countries, develop government policy, suppoet systems. As a results, the support must be made for public organization, small suppliers. The Response direction must be made for agents and private buyers. At the point of support systems, public organizations must implement the purchase systems and provide the verified informations of suppliers. And it's necessary to educate marketing and sales solutions. At the point of Response directions, it's necessary to make a standard for supply replaced MRO. And the beginning positioning directions of MRO-mall is needed to stress the differentials with private suppliers.

• Convergence Security Journal
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• v.18 no.5_1
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• pp.75-81
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• 2018

As industries converge in recent years, the impact of the use of convergence tools among industries on the security of the organization is increasing. However, organizational members lack the ability to adapt to introduction of new system because they are operating business around existing systems, and thus, security considerations are an environment that will inevitably emerge as a follow-up priority. In this study, we studied cost-effective options for factors that should be considered first in order to establish a security system for small and medium-sized healthcare institutions in the healthcare convergence industry. Specifically, the current legal system was considered and the security status was analyzed through prior research, and the necessary security solution/system was derived from small and medium-sized healthcare institutions. In addition, it analyzed relative priorities for cost-efficient deployment of security systems to those involved in small and medium-sized healthcare institutions in actual business environments and presented measures to establish a overall security.

• Genomics & Informatics
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• v.19 no.4
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• pp.48.1-48.10
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• 2021

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) encodes small envelope protein (E) that plays a major role in viral assembly, release, pathogenesis, and host inflammation. Previous studies demonstrated that pyrazine ring containing amiloride analogs inhibit this protein in different types of coronavirus including SARS-CoV-1 small envelope protein E (SARS-CoV-1 E). SARS-CoV-1 E has 93.42% sequence identity with SARS-CoV-2 E and shared a conserved domain NS3/small envelope protein (NS3_envE). Amiloride analog hexamethylene amiloride (HMA) can inhibit SARS-CoV-1 E. Therefore, we performed molecular docking and dynamics simulations to explore whether amiloride analogs are effective in inhibiting SARS-CoV-2 E. To do so, SARS-CoV-1 E and SARS-CoV-2 E proteins were taken as receptors while HMA and 3-amino-5-(azepan-1-yl)-N-(diaminomethylidene)-6-pyrimidin-5-ylpyrazine-2-carboxamide (3A5NP2C) were selected as ligands. Molecular docking simulation showed higher binding affinity scores of HMA and 3A5NP2C for SARS-CoV-2 E than SARS-CoV-1 E. Moreover, HMA and 3A5NP2C engaged more amino acids in SARS-CoV-2 E. Molecular dynamics simulation for 1 ㎲ (1,000 ns) revealed that these ligands could alter the native structure of the proteins and their flexibility. Our study suggests that suitable amiloride analogs might yield a prospective drug against coronavirus disease 2019.

• Genomics & Informatics
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• v.6 no.4
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• pp.227-230
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• 2008

Compounds of polyketide origin possess a wealth of pharmacological effects, including antibacterial, antifungal, antiparasitic, anticancer and immunosuppressive activities. Many of these compounds and their semisynthetic derivatives are used today in the clinic. Most of the gene clusters encoding commercially important drugs have also been cloned and sequenced and their biosynthetic mechanisms studied in great detail. The area of biosynthetic engineering of the enzymes involved in polyketide biosynthesis has recently advanced and been transferred into the industrial arena. In this work, we introduce a computational system to provide the user with a wealth of information that can be utilized for biosynthetic engineering of enzymes involved in post-PKS tailoring steps. Post-PKS tailoring steps are necessary to add functional groups essential for the biological activity and are therefore important in polyketide biosynthesis.