• 제목/요약/키워드: Site Response Analysis

검색결과 652건 처리시간 0.039초

화재대응 취약지역에서의 소방특수차량 이동제약요인 분석 : 서울시의 진입곤란지역을 대상으로 (Analysis of Mobility Constraint Factors of Fire Engines in Vulnerable Areas : A Case Study of Difficult-to-access Areas in Seoul)

  • 윤여름;김태은;최민지;황성주
    • 한국안전학회지
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    • 제39권1호
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    • pp.62-69
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    • 2024
  • Ensuring swift on-site access to fire engines is crucial in preserving the golden time and minimizing damage. However, various mobility constraints in alleyways hinder the timely entry of fire engines to the fire scene, significantly impairing their initial response capabilities. Therefore, this study analyzed the significant mobility constraints of fire engines, focusing on Seoul, which has many old town areas. By leveraging survey responses from firefighting experts and actual observations, this study quantitatively assessed the frequency and severity of mobility constraint factors affecting the disaster responses of fire engines. Survey results revealed a consistent set of top five factors regarding the frequency and disturbance level, including illegally parked cars, narrow paths, motorcycles, poles, and awnings/banners. A comparison with actual road-view images showed notable consistency between the survey and observational results regarding the appearance frequency of mobility constraint factors in vulnerable areas in Seoul. Furthermore, the study emphasized the importance of tailored management strategies for each mobility constraint factor, considering its characteristics, such as dynamic or static. The findings of this study can serve as foundational data for creating more detailed fire safety maps and advancing technologies that monitor the mobility of fire engines through efficient vision-based inference using CCTVs in the future.

두경부종양 환자에서 p53의 과발현과 방사선치료결과 (P53 Overexpression and Outcome of Radiation Therapy in Head & Neck Cancers)

  • 김인아;최일봉;강기문;장지영;김경미;박경신;김영신;강창석;조승호;김형태
    • Radiation Oncology Journal
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    • 제17권1호
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    • pp.1-8
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    • 1999
  • 목적 : 실험적으로 p53 종양억제유전자는 세포의 방사선에 대한 반응을 조절하는 것으로 알려져 있는데, 임상에서 p53의 변화와 방사선치료 후의 예후와의 상호관련성은 아직 명확하게 규명되지 않은 상태이다. 이에 두경부종양환자에서 흔히 관찰되는 p53의 변화가 방사선치료결과에 어떤 영향을 미칠 수 있는지를 알아보고자 하였다. 재료 및 방법 : 두경부종양으로 진단되어 근치적 방사선치료를 받은 55명의 환자를 대상으로 임상결과를 후향적으로 분석하였다. 각 환자의 치료전 종양조직의 paraffin section을 human p53단백질에 대한 monoclonal antibody (D-07)로 면역조직화학염색하여 labeling Index (number of labelded nuclei/total number of counted nuclei x100)를 구하여, 임상결과와 연관지어 분석하였다. 결과 : 전체환자의 67.2$\%$에서 p53의 기능이상을 시사하는 과발현 소견을 보였다. 원발병소에 따른 과발현 빈도는 oral cavity, larynx, hypopharynx, nasopharynx순으로 각각 100$\%$, 76$\%$, 67$\%$, 67$\%$, 38$\%$로 나타났다. 흡연자가 비흡연자에 비해 유의하게 높은 과발현 빈도를 보였다 (78.6$\%$, 30.8$\%$). 원발병소, 병기 및 Karnofsky peformance status가 방사선치료에 대한 반응율과 유의한 연관을 보였으며, p53의 과발현여부는 치료반응율에 유의한 영향을 미치지 못하는 것으로 나타났다. 무병생존율 및 전체생존율에 영향을 미치는 인자는 원발병소와 병기였고, p53의 과발현여부는 유의한 연관을 보이지 못하였다. 결론 : 근치적 방사선치료를 받은 두경부종양 환자에서, 면역조직화학염색에 의한 p53의 과발현율은 원발병소, 병기 및 흡연여부와 유관하였으며, 과발현여부가 치료반응율 및 생존율에 유의한 영향을 미치지 못하였다.

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압축력을 병용한 하악골 신장술 (MANDIBULAR DISTRACTION OSTEOGENESIS WITH COMPRESSION FORCE - BONE DENSITY, HISTOLOGICAL FINDINGS AND TMJ RESPONSE)

  • 황영섭;허준;김욱규;박성진;황대석;김용덕;정인교;김규천
    • Maxillofacial Plastic and Reconstructive Surgery
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    • 제28권6호
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    • pp.531-548
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    • 2006
  • The purpose of this study was to investigate the biomechanical, histologic findings of distracted regenerate and TMJ response in modified distraction osteogenesis (DO) technique combined with compression force as biomechanical stimulation method which has been suggested in 2002, and developed thereafter by authors. This study was performed with two experiments. First experiment was designed to explore the optimal ratio of compression force versus distraction force for the new DO technique. Second experiment was planned to evaluate the reaction of TMJ tissue, especially condyle, disc after application of the DO technique with compression force. Total 52 New Zealand adult male-rabbits with 3.0kg body weight were used for the study. For the first study, 30 adult male-rabbits underwent osteotomy at one side of mandibular body and a external distraction device was applied on each rabbit with same manner. In the control group of 10 rabbits, final 8 mm of distraction with 1 mm rate per day was done with conventional DO technique after 5 latency days. For the experimental group of 20 rabbits, a compression force with 1 mm rate per day was added to the distracted mandible on 3-latency day after over-distraction (over-lengthening). As the amount of the rate of compression versus distraction, experimental subgroup I (10 rabbits) was set up as 2 mm compression versus 10 mm distraction (1/5) and experimental subgroup II (10 rabbits) was set up as 3 mm compression versus 11 mm distraction (about 1/3). All 30 rabbits were set up to obtain final 8 mm distraction and sacrificed on postoperative 55 day to analysis on biomechanical, and histologic findings of the bone regenerates. For second study, 22 adult male-rabbits were used to evaluate TMJ response after the DO method application with compression force. In the control group, 10 rabbits was used to be performed with conventional DO method, on the other hand, in a experimental group of 10 rabbits, 10 mm distraction with 2 mm compression (1/5 ratio) was done. The remaining 2 rabbits served as the normal control group. Histomorphologic examinations on both condyle, histological studies on condyle, disc were done at 1, 2, 3, 4, 7 weeks after distraction force application. The results were as follows: 1. On the bone density findings, the experimental group II (force ratio - 1/3) showed higher bone density than the other experimental group (force ratio - 1/5) and control group (control group - $0,2906\;g/cm^2$, experimental group I - $0.2961\;g/cm^2$, experimental group II - $0.3328\;g/cm^2$). 2. In the histologic findings, more rapid bone maturation like as wide lamellar bone site, more trabeculae formation was observed in two experimental groups compared to the conventional DO control group. 3. In morphologic findings of condyle, there were no differences of size and architecture in the condyle in the control and experimental groups. 4. In histologic findings of condyles, there were thicker fiberous and proliferative layers in experimental group than those of control group until 2 weeks after distraction with compression force. But, no differences were seen between two groups on 3, 4, 7 weeks after compression. 5. In histologic findings of disc, more collagen contents in extracellular matrix, more regular fiber bundles, and less elastin fibers were seen in experimental group than control group until 2 weeks after distraction with compression. But, no differences were seen between two groups on 3, 4, 7 weeks after distraction with compression. From this study, we could identify that the new distraction osteogenesis technique with compression stimulation might improve the quality of bone regeneration. The no remarkable differences on TMJ response between control and experimental groups were seen and TMJ tissues were recovered similarly to normal TMJ condition after 3 weeks.

중심선 악성 세망증의 방사선 치료 결과 (Radiotherapy Results of Midline Malignant Reticulosis (MMR))

  • 윤상모;김재철
    • Radiation Oncology Journal
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    • 제14권4호
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    • pp.291-297
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    • 1996
  • 목적 : 중심선 악성 세망증의 방사선 치료 후 생존율, 실패 양상, 그리고 예후 인자에 대해 분석하고, 최근 대두되는 화학요법의 필요성에 대해 고찰해 보고자 본 연구를 시행하였다. 대상 및 방법 : 1985년 6원부터 1992년 11월까지 방사선 치료를 위해 의뢰된 23예의 중심선악성 세망증 환자를 대상으로 후향적 분석을 실시하였다. 연령 분포는 17세부터 71세까지 광범위 했고 (중앙값 39세), 남자 19예와 여자 4예로 남성에서 호발하였다. $30\%$ (7/23)의 환자에서 발열, 체중 감소, 혹은 전신 쇠약감 등의 전신 증상을 호소하였다. 상기도 병소는 비강이 가장 빈번하게 침범되었고, 진단 시 경부 임파절 전이를 보인 경우는 없었으며, 원격 전이를 보인 경우가 2예 있었다. 방사선 치료는 6 MV X-ray를 이용하여 1회 선량 1.8 Gy씩, 주 5회, 총선량 $45\~54$ Gy (중앙간 50.4 Gy)를 조사 하였다. 첫 치료 시 화학요법을 시행한 예는 없었다. 결과 : 방사선 치료에 대한 반응은 완전 관해 $70.6\%$ (12/17), 부분 관해 $29.4\%$ (5/l7) 였으며, 5년 생존율은 $52.4\%$, 10년 생존율은 $44.1\%$였다. 방사선 치료에 완전 관해를 보인 환자군이 부분 관해를 보인 환자관보다 5년 생존율이 높았다 ($66.9\%$ vs. $20\%$, p=0.004). 성별, 나이, 진단시까지 증상의 지속기간, 전신 증상의 유무, 그리고 원발 병소의 수에 따른 생존율의 차이를 비교해 보았으나 유의한 차이를 보이지 않았다. 치료 실패 양상은 원발 병소 재발 1예, 주위 조직 재발 1예, 원발 병소 재발 및 원격전이 1예, 원격전이 2예, 그리고 악성 임파종으로 이행 1예 등으로 관찰되었다. 실패 양상과 관련된 요인은 찾을 수 없었다. 결론 : 중심선 악성 세망증의 방사선 치료 후 장기 생존과 관련성이 있는 요인은 완전 관해 유무였다. 따라서 첫 치료 시 완전 관해를 이루기 위한 다각적인 노력이 필요하겠다. 원격 전이가 $17\%$에서 관찰되었고 그것이 사망의 요인 중 하나였다. 그러나 약 $50\%$의 환자는 국소 방사선치료만으로도 장기 생존이 가능하였다. 따라서, 모든 환자에서 첫 치료 시 화학 요법을 시행한다 는 것은 바람직하지 않고, 원격 전이와 관계가 있는 요인에 대한 전향적 연구가 선행되고 난 뒤에 시행하는 것이 좋겠다.

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코발트전극과 자동시험장치를 이용한 파프리카 양액 내 무기인산 측정 (Determination of Inorganic Phosphate in Paprika Hydroponic Solution using a Laboratory-made Automated Test Stand with Cobalt-based Electrodes)

  • 김학진;손동욱;권순구;노미영;강창익;정호섭
    • Journal of Biosystems Engineering
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    • 제36권5호
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    • pp.326-333
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    • 2011
  • The need for rapid on-site monitoring of hydroponic macronutrients has led to the use of ion-selective electrodes, because of their advantages over spectrophotometric methods, including simple methodology, direct measurement of analyte, sensitivity over a wide concentration range, and low cost. Stability and repeatability of response can be a concern when using multiple ion-selective electrodes to measure concentrations in a series of samples because accuracy might be limited by drifts in electrode potential. A computer-based measurement system could improve accuracy and precision because of both consistent control of sample preparation and easy calibration of sensors. Our goal was to investigate the applicability of a cobalt-based electrode used in conjunction with a laboratory-made automated test stand for quantitative determination of ${PO_4}^-$ in hydroponic solution. Six hydroponic solutions were prepared by diluting highly concentrated paprika hydroponicsolution to provide a concentration range of 1 to 300 ppm $PO_4$-P. A calibration curve relating electrode response to phosphate in paprika hydroponic solution titrated to pH 4 with 0.025M KHP was developed based on the Nikolskii-Eisenman equation with a coefficient of determination ($R^2$) of 0.94. The laboratory-made test stand consisting of three cobalt-based electrodes measured phosphate concentrations similar to those obtained with standard laboratory methods (a regression slope of 0.98 with $R^2$ = 0.80). However, the y intercept was relatively high, 30 ppm, probably due to the relatively large amount of variation present among multiple measurements of the same sample. Further studies on the high variation in EMFs obtained with cobalt electrodes during replicate measurements were required for P estimations comparable to those obtained with standard laboratory instruments.

상악동의 선양낭성암종 (Adenoid Cystic Carcinoma of the Maxillary Sinus)

  • 금기창;박희철;김귀언;서창옥;정은지;김세헌;김영호;홍원표
    • 대한두경부종양학회지
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    • 제12권2호
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    • pp.217-223
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    • 1996
  • A retrospective analysis was performed to assess the relationship between the treatment modalities and treatment results in patients with adenoid cystic carcinoma of the maxillary sinus. From Feb. 1977 to March 1994, 10 patients with the disease were treated at the Department of Radiation Oncology, Yonsei Cancer Center, Yonsei University College of Medicine. Six men and 4 women were presented with median age of 57 years. According to AJCC TNM system, all patients except one had advanced T3 and T4 disease. Only one patient had the regional metastasis to lymph node but none of them had hematogenous metastasis on initial admission. One patient(Group 1) was treated with surgery alone, 3 patients(Group 2) were treated with definitive radiotherapy and 6 patients(Group 3) were treated with combination of surgery and radiotherapy. One patient who was treated with surgery alone had experienced a locoregional recurrence 9 months later and 3 patients who were treated with radiation therapy alone had PRs(partial response) followed by the subsequent progression of the local disease. Whereas all patients who were treated with combination of surgery and radiation therapy had CRs(complete response). Among them, only one patient was recurred in the primary site, who was salvaged by reoperation and reirradiation therapy. In conclusion, combination of surgery and radiotherapy resulted in the best treatment modality for adenoid cystic carcinoma of the maxillary sinus. Improved radiotherapy technique and development of multimodality treatment are needed to improve the local control and the survival rate in patients with advanced adenoid cystic carcinoma of the maxillary sinus.

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히로시마에서 후쿠시마까지, 핵과 미술가의 대응 (From Hiroshima to Fukushima: Nuclear and Artist Response in Japan)

  • 최태만
    • 미술이론과 현장
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    • 제13호
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    • pp.35-71
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    • 2012
  • The purpose of this essay is to examine the responses of artists on nuclear experiences through an analysis of the nuclear images represented in contemporary Japanese art. Japan has previously as twice experienced nuclear disaster in 20th century. The first atomic bombs were dropped in 1945 as well as the 5th Fukuryumaru, Japanese pelagic fishing boat, exposed by hydrogen bomb test operated by the US in 1954 nearby Bikini atoll. Due to Tsunami taken place by the great earthquake that caused the meltdown of Fukushima Nuclear Power Plant in March 2010, Japan is being experienced a nuclear disaster again. Despite practical experiences, comtemporary Japanese art has avoided the subject of nuclear disasters since the end of the Asia-Pacific War for a variety of reasons. Firstly, GHQ prohibited to record or depict the terrible effect of atomic bomb until 1946. Secondly, Japanese government has tried to sweep the affair under the carpet quite a while a fact of nuclear damage to their people. Because Japan has produced numerous war record paintings during the Second World War, in the aftermath of the defeated war, most of Japanese artists thought that dealing with politics, economics, and social subject was irrelevant to art as well as style of amateur in order to erase their melancholic memory on it. In addition, silence that was intended to inhibit victims of nuclear disasters from being provoked psychologically has continued the oblivion on nuclear disasters. For these reasons, to speak on nuclear bombs has been a kind of taboo in Japan. However, shortly after the atomic bomb dropped on Hiroshima, the artist couple Iri and Toshi Maruki visited to ruin site as a volunteer for Victim Relief. They portrayed the horrible scenes of the legacy of nuclear bomb since 1950 based on their observation. Under the condition of rapid economical growth in 1960s and 1970s, Japanese subculture such as comics, TV animations, plastic model, and games produced a variety of post apocalyptic images recalling the war between the USA and Japanese militarism, and battle simulation based on nuclear energy. While having grown up watching subculture emerged as Japan Neo-Pop in 1990s, New generation appreciate atomic images such as mushroom cloud which symbolizes atomic bomb of Hiroshima. Takashi Murakami and other Neo-Pop artists appropriate mushroom cloud image in their work. Murakami curated three exhibitions including and persists in superflat and infantilism as an evidence in order to analyze contemporary Japanese society. However, his concept, which is based on atomic bomb radiation exposure experience only claimed on damage and sacrifice, does not reflect Japan as the harmer. Japan has been constructing nuclear power plants since 1954 in the same year when the 5th Fukuryumaru has exposed until the meltdown of Fukushima Nuclear Plant although took place of nuclear radiation exposures of Three Mile and Chernobyl. Due to the exploding of Fukushima Nuclear Power Plant, Japan reconsiders the danger of nuclear disaster. In conclusion, the purpose of this paper may be found that the sense of victim which flowed in contemporary art is able to inquire into the response of artist on the subject of nuclear as well as the relationship between society, politics, culture, and modern history of Japan and international political situation.

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국소 진행된 두경부암의 병합요법 : 치료 방법에 따른 비교 (Combined Modality Treatment in Head and Neck Cancer)

  • 박인규;이호준;윤상모;김재철
    • 대한두경부종양학회지
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    • 제17권1호
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    • pp.32-37
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    • 2001
  • Objectives: We performed this study to compare the short term results of induction chemotherapy and radiotherapy versus concurrent chemoradiotherapy in patients with locally advanced head and neck cancer. Materials and Methods: From Oct. 1985 to May 1998, 121 patients with locally advanced head and neck cancer were treated with induction chemotherapy and radiotherapy (induction group) or concurrent chemoradiotherapy (concurrent group), and a retrospective analysis was done. Induction chemotherapy was done for 97 patients, and concurrent chemotherapy for 24 patients. Age, sex, performance status, and pathologic types were evenly distributed between two groups. Primary site showed nasopharynx(72.2%), oropharynx(27.8%) in induction group, and nasopharynx(50%), oropharynx(50%) in concurrent group. Chemotherapy regimen was CF(cisplatin and 5-fluorouracil) for 67 patients and CVB (cisplatin, vincristine, bleomycin) for 30 patients in induction group, and CF for all of 24 patients in concurrent group. Proportion of patients treated with more than 2 cycles of planned chemotherapy was 94.8% in induction group and 87.5% in concurrent group. Conventionally fractionated radiotherapy with daily fraction size of 1.8-2.0Gy and 5 fractions/week was done. Total dose was 61-95Gy (median 73.4Gy) for induction group, and 69.4-75.4Gy (median 69.4Gy) for concurrent group. Follow-up time was 4-161 months (median 38 months) for induction group, 7-35 months (median 21.5 months) for concurrent group, respectively. Results: According to treatment modality, overall 2-year survival rates were 68.0% for induction group, 74.3% for concurrent group (p>0.05). two-year disease-free survival rates were 51 % and 74% (p=0.05). Complete response rates were 67.4% for induction group and 83.3% for concurrent group (p=0.09). The incidence of grade 3-4 hematologic toxicity (2.1% vs. 25%, p=0.001) and grade 3-4 mucositis (9.3% vs. 37.5%, p=0.002) during radiotherapy was higher in concurrent group. Conclusion: Concurrent chemoradiotherapy showed a trend of improvement in short-term survival and treatment response when compared with induction chemotherapy and radiotherapy in locally advanced head and neck cancer. A more controlled randomized trial is needed.

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지급자재 조달관리부담 평가에 기초한 중소기업 공사용자재 직접구매제도 대응방안: 공공아파트를 공급하는 발주자를 중심으로 (Developing Response Plan for the Direct Buying System for SME's Construction Materials based on the Analysis of Material Procurement Management Load: Focused on the Owner Providing Public Apartment Housing)

  • 송상훈;방종대;손정락
    • 토지주택연구
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    • 제4권4호
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    • pp.425-434
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    • 2013
  • 중소기업청은 일정규모 이상의 공공건설사업에 대해 일반공사와 의무적으로 분리하여 직접 구매해야 하는 123개 공사용자재 제품군을 지정하고, 법에서 정한 바에 따라 발주기관이 자재를 직접 구매하여 수급인에게 공급하도록 하고 있다. 본 연구에서는 이러한 공사용자재 직접구매제도 하에서 공공아파트 건설 현장에 투입되는 지급자재가 지니는 다양한 특성과 관리요인을 발주자 입장에서 종합적으로 고려하여, 주요관리대상 자재를 파악하고, 자재 조달 프로세스를 기반으로 이들에 대한 적정 관리 방안을 제시하였다. 즉, 조달경로, 현장특화정도, 입주자 요구수준, 업체 책임범위, 납품분할정도, 현장작업 요구도, 부속자재 필요도, 검수조건 등 지급자재가 가지는 주요 관리요인을 적용하여 공공아파트 건설사업에 적용되는 43개 직접 구매 대상품목의 조달관리부담을 평가한 결과, 상대적으로 높은 조달관리노력이 요구되는 주요관리대상그룹에는 목재창호, 알루미늄창호, 승강기, 목재마루재, 레미콘, 타일, 합성수지창호가 포함되었고, 그 중 알루미늄창호와 타일은 집중관리대상으로 분류되었다. 나아가 직접구매제도의 영향에 따른 집중관리대상 자재에 대한 대응방안은 발주자 입장에서 실태, 문제점, 관리측면의 주요 고려사항을 반영하여 작성하였으며, 실질적 수량 산출, 명확한 발주세부조건 정비, 생산 전후 활동 활성화, 하자보수 물량 확보, 공종별 간섭 사전 협의 및 해소 등이 필수적인 관리활동으로 나타났다.

포스트 코로나 시대 관광 트렌드를 반영한 농촌체험마을 조성방안 연구 - 전라북도 완주군 소양면 위봉마을을 사례로 - (A Study on the Creation Rural Experience Village Reflecting the Travel trends of the Post-Corona - A Case of Wi-bong Village in Jeollabuk-do -)

  • 안필균;엄성준;조숙영;김상범
    • 농촌계획
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    • 제26권4호
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    • pp.27-39
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    • 2020
  • With the COVID-19 pandemic, the global economy has stagnated and our daily lives have changed. The rural economy is also experiencing damage, such as an average of 65% or more decrease in the number of visitors to rural experience resort villages due to the spread of COVID-19. In order to minimize the damage arising from the prolonged coronavirus, a hospitality system in response to changes in rural tourism behavior and consumer demand is needed to revitalize rural areas and maintain continuous economic independence. Therefore, this study attempted to find ways to utilize landscape resources such as education, culture, history, and ecology in order to complement the existing experience programs in connection with local resources and local environment. Wibong Village, which is the subject of the study, attempted to revitalize the village using the resources through the "Creative village creation" project in 2015. Due to poor management of historical resources, difficulty in operating experience programs, and response to changes in the natural environment, the rate of implementation of the project plan was very low. Currently, the demand for experience is also decreasing due to the COVID-19 effect, so it was judged that it was necessary to develop an experience village program suitable for the needs of experienced visitors by discovering additional local resources for the continuous operation of the experience village. In order to solve the problem of the use of landscape resources and the spatial composition of the study site, additional investigations of local resources were made, and an experience program course that could be operated by theme was proposed by configuring a space suitable for the use of landscape resources. By dividing the additionally investigated landscape resources into history, ecology, and region, an experiential course was created to separate the traffic lines, and the space composition for large-scale experienced visitors that had been previously operated was constructed in a form suitable for the post-corona era. In addition, at least two experiential tour courses that can be operated by period were proposed to maintain economic effects. Starting with this study, if further research on the creation and spatial composition of a rural experience village centered on the connection with the region, it will be used as research results that can be referenced in projects such as village creation, rural space planning, and living area analysis. It is expected that it will be able to effectively cope with the construction of a rural area suitable for the post-corona era, where demand is expected to increase in the future.