• Title/Summary/Keyword: Single-Cell Model

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Dynamic Characteristics of Composite Thin-Walled Beams with a Chord wise Asymmetric Cross-Section: I. Single-Cell (시위 방향 비대칭 단면의 복합재료 박벽보의 동특성 연구: I. 단일-셀)

  • Kim, Keun-Taek
    • Journal of Aerospace System Engineering
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    • v.12 no.6
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    • pp.41-49
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    • 2018
  • In this study, the theoretical dynamic characteristics of a thin-walled composite beam with a single-cell of chordwise asymmetric cross-section was studied. Mathematical modeling was done by considering the transverse shear effects, the warping restraint effects, the constant taper ratio in the longitudinal direction of the beam, and the geometrical cross-section ratio. The mass coefficients, stiffness coefficients, and Eigen frequencies of the selected section were investigated. In particular, the effects of the taper ratio and cross-section ratio of the model on the Eigen frequencies were analyzed and compared when the asymmetry of the section was considered and the warping function was not corrected.

Relationship between Radiosensitivity and Repair Capacity in Human Epithelial Cancer Cell Lines (인체 상피암 세포주에서 방사선감수성과 손상회복의 상관관계에 관한 연구)

  • Koh, Kyoung-Hwan;Ha, Sung-Whan;Park, Charn-Il
    • Radiation Oncology Journal
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    • v.11 no.1
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    • pp.17-27
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    • 1993
  • To investigate the relationship between radiosensitivity and postirradiation recovery in human cancer cells, a study was performed using human cancer cell lines-A549, CaSki, SNU-C5 and PCI-13. For the study of radiosensitivity, single doses of 2, 4, 6, 8, 10, 12, and 14 Gy were given and for postirradiation recovery, two fractions of 4 Gy were separated with a time interval of 0, 0.5, 1, 1.5, 2, 2.5, 3, 4, 5, or 6 hours. Surviving fraction was estimated using colony forming ability. Surviving fractions at 2 Gy (SF2) were 0.496 (0.570-0.412) for A549, 0.496 (0.660-0.332) for CaSki, 0.386 (0.576-0.216) for SNU-C5, and 0.185 (0.247-0.123) for PCI-13. By statistical analysis the SF2 of PCI-13 was lower significantly than those of others (p<0.05). This difference was also observed at 4, 6 and 8 Gy dose levels. At 6 and 8 Gy the surviving fractions of SNU-C5 were also lower significantly than A549 and CaSki (p<0.05). By the analysis with linear quadratic model, the values of ${\alpha}$ for A549, CaSki, SNU-C5 and PCI-13 were 0.3016, 0.3212, 0.4327 and 0.8423, respectively, and those of ${\beta}$ were 0.02429, 0.02009, 0.03349 and 0.00059, respectively. So, the value of ${\alpha}$ showed increasing tendency with decreasing SF2. By the multitarget single hit model the values of Do for A549, CaSki, SUN-C5 and PCI-13 were 1.97, 1.97, 1.46 and 0.81, respectively, and those of n were 1.53, 1.50, 1.56 and 2.28, respectively. So, the value of Do decreased with decreasing SF2. Post-irradiation recovery reached plateau at around 2 hours. Recovery ratio at plateau phase ranged from 1.2 to 4.2; the value were 1.2 for PCI-13, 3.2 for CaSki, 3.3 for SNU-C5, and 4.2 for A549. Recovery rate well correlated with SF2, and increased with increasing Do and decreasing ${\alpha}$. According to above results, the intrinsic radiosensitivity was quite different among the tested cell lines; PCI-13 was the most sensitive and A549 and CaSki was similar. This difference of radiosensitivity is thought to be partly due to the difference in amount of postirradiation recovery. By linear quadratic model the difference of ${\alpha}$ values was very high, and by multitarget single hit model the difference of Do value was significantly high among four cell lines.

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Mathematical Model for Adsorption of Berberine on Encapsulated Adsorbent (캡슬에 고정화된 흡착제에의 Berberine의 흡착에 관한 수학적 모델)

  • 최정우;조상원이원홍
    • KSBB Journal
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    • v.10 no.4
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    • pp.358-369
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    • 1995
  • A mathematical model using local thermodynamic equilibrium isotherms for adsorption in encapsulated adsorbent is proposed in order to optimize the design parameters in situ bioproduct separation process. The model accurately follows the experimental data on the adsorption of berberine, secondary metabolite produced in Thaictrum rugosum plant cell culture. The adsorption rate on encapsulated adsorbent is compared with that on alginate-entrapped adsorbent. The result shows that the higher loading capacity in encapsulated adsorbent is mainly due to the increase in the maximum solid phase concentration. Based on the adsorption rate and loading capacity, the encapsulated adsorbent would be more useful than the entrapped adsorbent when used in situ bioproduct separation process. Design parameters in situ bioproduct separation process, such as the size of the capsule, membrane thickness, the ratio of capsule volume to bulk volume, the ratio of single capsule volume to total capsule volume and the adsorbent content in the capsule, are evaluated by using the model. The ratio of single capsule volume to total capsule volume is the most effective parameter for adsorption of berberine on encapsulated adsorbent.

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A Single Cell Multimedia Fate Model for Endocrine Disrupting Chemicals

  • Park, Kyunghee;Junheon Youn;Daeil Kang;Lee, Choong;Lee, Dongsoo;Jaeryoung Oh;Sunghwan Jeon;Jingyun Na
    • Proceedings of the Korea Society of Environmental Toocicology Conference
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    • 2003.05a
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    • pp.149-149
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    • 2003
  • To understand environmental paths of the transport and accumulation of endocrine disrupting chemicals (EDCs), a single cell multimedia fate model has been constructed and evaluated. The EDCs of concern were PAHs, Organochlorine Pesticides (OCPs), PCBs, Alkyl phenols, and phthalates. An evaluation model was designed for the multimedia distribution, including air, water, soil, sediment and vegetation. This model was verified using reported values and via monitoring data. Based on collected data, the distribution trends of EDCs with respect to environmental media were analyzed. Those results have applied to the model for the prediction of the spatial and temporal distribution of EDCs in Seoul. Especially, phenol compound, phthalates, PAHs, PCBs and organochlorine pesticides were estimated and the model was verified. This model was successfully conducted to environmental media, such as air (vapor and suspended particles), soils (forest soil, bare soil, and cement-concrete covered soil), water (dissolved and suspended solids), sediment, trees (deciduous and coniferous). The discrepancies between the model prediction and the measured data are approximately within or near a factor of 10 for the PAHs of three rings through that of six rings, implying that multimedia distribution of the PAHs could be predicted with a factor of 10. Concerning about the air equilibrium may be assumed, a fugacity at steady state is similar in all environmental media. Considering the uncertainties of this model, the use of equilibrium models may be sufficient for assessing chemical fates. In this study, a suggestion was made that modeling and estimation of chemicals in environmental multimedia be rigorously evaluated using the measured flux data. In addition, these data should be obtained, for example, from the precise and standardized inventory of the target chemicals. The model (EDC Seoul) will be refined in an on-going research effort and will be used to support decision-making concerning the management of EDCs.

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A Study on Radio Resource Management for Multi-cell SC-FDMA Systems (다중셀 SC-FDMA를 위한 무선자원 관리기법에 관한연구)

  • Chung, Yong-Joo
    • Journal of Korea Society of Industrial Information Systems
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    • v.15 no.4
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    • pp.7-15
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    • 2010
  • This study proposes a rad o resource management scheme to maximize the performance of the LTE(Long Term Evolution) uplink, using SC-FDMA(Single Carrier-Frequency Division Multiple Access). Rather than the single-cell SC-FDMA system the existing studies are mainly concerning, this study focuses on multi-cell system which needs considering the interaction among cells. Radio resource management is divided into two phases, planning and operation phases. The former is for the master eNB(e-NodeB) to allocate RBs(radio bearer) to eNB, the latter for eNB to assign RBs to the mobiles in the cell. For each phase, an optimization model and greedy algorithm are proposed. Optimization models aim to maximize the system performance while satisfying the constraints for both QoS and RB continuity. The greedy algorithms, like generic ones, move from a solution to a neighboring one having the best objective value among neighboring ones. From the numerous numerical experiments, the performance and characteristics of the algorithms are analyzed. This study is expected to play a volunteering role in radio resource management for the multi-cell SC-FDMA system.

Simulation of Solar Cell Maximum Power Point Using Matlab (Matlab을 이용한 솔라셀의 최대전력점 시뮬레이션)

  • Lee K.Y.;Kim H.S.;Park J.M.;Cho G.B.;Baek H.L.;Hanyeong College D.H. Kim
    • Proceedings of the KIPE Conference
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    • 2003.07a
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    • pp.204-207
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    • 2003
  • PV model is presented based on the shockley diode equation. The simple model has a photo-current source, an single diode junction and a series resistance and includes temperature dependences. An accurate PV module electrical model is presented, matching with boost converter MPPT strategy and demonstrated in Matlab for a typical general purpose solar cell. Given solar insolation and temperature, the model returns current vector and MPP.

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Chemopreventive Effect of Vegetable or Fruit Extract Against Total Diesel Exhaust Particle Extract in NIH/3T3 Cells Using Alkaline Single Cell Gel Electrophoresis (총 디젤분진의 DNA 손상작용과 야채 및 과일추출물의 보호효과)

  • Heo Chan;Kim Nam-Yee;Heo Moon-Young
    • Environmental Analysis Health and Toxicology
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    • v.21 no.2 s.53
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    • pp.127-138
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    • 2006
  • In urban areas, diesel exhaust particles (DEP) are probably a major component of particulate matters, especially in Korea where drive many diesel vehicles. The aim of this study was to investigate genotoxic effects of DEP using single ceil gel electrophoresis. In order to evaluate the mechanisms of DEP genotoxicity, the rat microsome mediated and DNA repair enzyme treated comet assays together with conventional comet assay were performed. Total diesel particles (DEPT) was collected without site fractionation from diesel engine bus and dichloromethane extract was obtained. The organic extract of DEPT revealed DNA damage itself in NIH/3T3 cells. The level of DNA breaks plus oxidative DNA lesions and microsome mediated DNA damage was assessed by modified single cell gel eletrophoresis. DEPT was able to induce oxidative DNA damage as well as microsome mediated DNA damage. Vitamin C as an model antioxidant reduced DNA damage in endonuclase III treated comet assay. One of flavonoid, galangin as a CYP1A1 inhibitor. reduced DNA damage in the presence of S-9 mixture. $DEP_T$ is the sources of oxidative stress, but antioxidants can significantly reduce oxidative DNA dmage. And $DEP_T$ may contain indirect mutagens which can be inhibited by CYP1A1 inhibitors. The ethanol extracts of the mixed vegetables (BV) or the mixed fruits (BF) were evaluated for their in vitro antigenotoxic effects. BV and BF showed potent Inhibitory effects against DEPT induced DNA damage with oxidative DNA lesions and in the prescence of S-9 mixture. These results indicate that BV and BF could prevent cellular DNA damage by inhibiting oxidative stress and suppressing cytochrome P4501A1 in cell culture.

Computer Simulation of Liquid-Fuelled Combustor in Hot Vitiated-Air Stream (고온.저산소 농도영역중의 분무연소해석)

  • 김태한;최병륜
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.17 no.12
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    • pp.3187-3195
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    • 1993
  • Combustion of liquid-fuelled combustion in a high-temperature vitiated-air stream was studied. The mathematical formulation comprise the application of Eulerian conservation equation to the gas phase and Lagrangian equation of droplet motion. The latter is coupled with a droplet-tracking technique (PSI-CELL Model) which regard the droplet phase as a source of mass, momentum, and energy to the gaseous phase. Reaction rate is determined by taking into account the Arrhenius reaction rate based on a single-step reaction mechanism. The calculated profiles show somewhat uncertainess at the upstream, but bases data for designing the combustor followed by 2-phase flow were obtained.

PERFORMANCE ANALYSIS OF AAL MULTIPLEXER WITH CBR TRAFFIC AND BURSTY TRAFFIC

  • Park, Chul-Geun;Han, Dong-Hwan
    • Journal of applied mathematics & informatics
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    • v.8 no.1
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    • pp.81-95
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    • 2001
  • This paper models and evaluates the AAL multiplexer to analyze AAL protocol in ATM networks. We consider an AAL multiplexer in which a single periodically determinsitic CBR traffic stream and several variable size bursty background traffic streams are multiplexed and one ATM cell stream goes out. We model the AAL multiplexer as a B/sup X/ + D/D/1/K queue and analyze this queueing system. We represent various performance measures such as loss probability and waiting time in the basis of cell and packet.

Performance Analysis of NTT/BT Protocol (NTT/BT 프로토콜의 성능 분석)

  • 이창훈;백상엽;이동주
    • Journal of the Korean Operations Research and Management Science Society
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    • v.22 no.2
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    • pp.99-123
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    • 1997
  • Performance analysis of NTT/BT protocol is investigated, which is a GFC (Generic Flow Control) ptotocol in ATM (Asynchronous Transfer Mode ) network and is based on cyclic reset mechanism. THe mean cell delay time is proposed as a performance measure of NTT/BT protocol. The mean cell delay time is defined as the duration from the instant the cell arrives at the transmission buffer until the cell is fully transmitted. The process of cell transmission can be described as a single server queueing modle with two dependent services. By utilizing this model, mean cell delay time is obtained and sensitivity of the factors such as window size and reset period is also analysed.

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