• Title/Summary/Keyword: Single crossing

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Association Study of ANK3 Polymorphism and Risk of Schizophrenia (ANK3 유전자 다형성과 조현병의 연관성에 대한 연합연구)

  • Yang, So Yung;Huh, Ik-Soo;Cho, Eun Young;Choi, Mi Ji;Park, Taesung;Lee, Yu-Sang;Hong, Kyung Sue
    • Korean Journal of Biological Psychiatry
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    • v.22 no.4
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    • pp.173-178
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    • 2015
  • Objectives Previous genome-wide association studies have indicated the association between ankyrin 3 (ANK3) and the vulnerability of schizophrenia. We investigated the association between single nucleotide polymorphisms (SNPs) covering the whole ANK3 locus and schizophrenia in the Korean population. Methods The study subjects were 582 patients with schizophrenia and 502 healthy controls. Thirty-eight tag SNPs on ANK3 and five additional SNPs showing significant association with schizophrenia in previous studies were genotyped. Results Three (rs10994181, rs16914791, rs1938526) of 43 SNPs showed a nominally significant association (p < 0.05) with at least one genotype model. But none of these associations remained significant after adjusting for multiple testing errors with Bonferroni's correction. Conclusions We could not identify a significant association between ANK3 and schizophrenia in the Korean population. However, three SNPs showing an association signal with nominal significance need to be investigated in future studies with higher statistical power and more specific phenotype crossing the current diagnostic categories.

Association between Polymorphisms of Lipoprotein Lipase Gene and Chicken Fat Deposition

  • Liu, Rui;Wang, Yachun;Sun, Dongxiao;Yu, Ying;Zhang, Yuan
    • Asian-Australasian Journal of Animal Sciences
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    • v.19 no.10
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    • pp.1409-1414
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    • 2006
  • The objective of this study was to screen single nucleotide polymorphisms (SNPs) of the chicken lipoprotein lipase gene (LPL), using 545 F1 hybrids developed from $4{\times}4$ diallel crossing of four chicken breeds, and to analyze the associations between polymorphisms of the LPL and chicken fat deposition traits. PCR-SSCP was used to detect SNPs in LPL. Fifteen sets of primers were designed to amplify DNA fragments covering the 5'flanking and coding regions of LPL. It showed that there existed 5 polymorphic loci in the 5'flanking region and coding region, respectively. Association analysis was carried out between 10 polymorphic loci and intermuscular fat width, abdominal fat weight, and thickness of subcutaneous fat using ANCOVA, respectively. The results indicated that, in the 5'flanking region, the loci d and e significantly affected thickness of subcutaneous fat (p<0.05), abdominal fat weight (p<0.01) and subcutaneous fat (p<0.05), while in the coding region, synonymous mutation in exon 8 was significantly associated with intermuscular fat width (p<0.05), however, the non-synonymous mutations in exon 7 and exon 9 did not show statistically significant effects on fat deposition traits in this study.

Characteristic Analysis of Multicell Convective System that Occurred on 6 August 2013 over the Korean Peninsula (2013년 8월 6일 한반도에서 발달한 다세포(Multicell) 대류계의 특성 분석)

  • Yoon, Ji-Hyun;Min, Ki-Hong
    • Atmosphere
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    • v.26 no.2
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    • pp.321-336
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    • 2016
  • Damages caused by torrential rain occur every year in Korea and summer time convection can cause strong thunderstorms to develop which bring dangerous weather such as torrential rain, gusts, and flash flooding. On 6 August 2013 a sudden torrential rain concentrated over the inland of Southern Korean Peninsula occurred. This was an event characterized as a mesoscale multicellular convection. The purpose of this study is to analyze the conditions of the multicellular convection and the synoptic and mesoscale nature of the system development. To this end, dynamical and thermodynamic analyses of surface and upper-level weather charts, satellite images, soundings, reanalysis data and WRF model simulations are performed. At the beginning stage there was a cool, dry air intrusion in the upper-level of the Korean Peninsula, and a warm humid air flow from the southwest in the lower-level creating atmospheric instability. This produced a single cell cumulonimbus cloud in the vicinity of Baengnyeongdo, and due to baroclinic instability, shear and cyclonic vorticity the cloud further developed into a multicellular convection. The cloud system moved southeast towards Seoul metropolitan area accompanied by lightning, heavy precipitation and strong wind gusts. In addition, atmospheric instability due to daytime insolation caused new convective cells to develop in the upstream part of the Sobaek Mountain which merged with existing multicellular convection creating a larger system. This case was unusual because the system was affected little by the upper-level jet stream which is typical in Korea. The development and propagation of the multicellular convection showed strong mesoscale characteristics and was not governed by large synoptic-scale dynamics. In particular, the system moved southeast crossing the Peninsula diagonally from northwest to southeast and did not follow the upper-level westerly pattern. The analysis result shows that the movement of the system can be determined by the vertical wind shear.

A Single Camera based Method for Cubing Rectangular Parallelepiped Objects (한대의 카메라에 기반한 직육면체의 부피 계측 방법)

  • Won, Jong-Won;Chung, Yun-Su;Kim, Woo-Seob;You, Kwang-Hun;Lee, Yong-Joon;Park, Kil-Houm
    • Journal of KIISE:Computing Practices and Letters
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    • v.8 no.5
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    • pp.562-573
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    • 2002
  • In this paper, we propose a method for measuring the volume of packages for the efficient handling of the packages. Using the geometrical characteristics of the rectangular parallelepiped type objects, the method measures the volume of packages with one camera only in real time. In preprocessing of volume measurement, the method extracts outer lines of the object and then crossing points of the lines as feature points or vertexes. From these cross points(-feature points-), the volume of the package is calculated. Compared to the direct feature extraction, the proposed method shows especially the blurring robust result by using the line for feature extraction. Additionally, the method can get the stable result by considering object's direction. From experimental results, it is demonstrated that this method is very effective for the real time volume measurement of the rectangular parallelepiped.

Nipple Reconstruction with the Double Opposing Plow Flap: A Case Report (이중 대립 쟁기피판을 이용한 유두 재건술: 증례보고)

  • Heo, Chan Yeong;Eun, Seok Chan;Baek, Rong Min;Minn, Kyung Won
    • Archives of Plastic Surgery
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    • v.34 no.4
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    • pp.490-492
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    • 2007
  • Purpose: Nipple reconstruction is an important step in breast reconstruction after mastectomy. There are considerable number of reconstructive methods developed over the past years. Each of these has not only its own special advantages, but also limitations. Therefore, no single method has become the overwhelming favorite. Sometimes it seems to be compromised when the nipple must be located directly over a linear scar. Methods: A 48-year-old female patient received a central lumpectomy with circumareolar resection of the nipple areolar complex 4 months ago. The newly designed nipple must be positioned directly astride a scar. We drew two equal-sized rectangular flaps sharing a common limb on a transverse scar and the result was two opposing plow form. Each flap size was about 1.3 cm wide and 2.5 cm long. First we elevated the flap from the distal part at a deep dermal plane, then deepened the level of dissection to raise the dermal-fat flaps. The donor site could be closed directly without any dog-ear deformity. Then we folded down the elevated flaps and loosely sutured skin with nonabsorbable materials. Each flap inner side was approximated side by side. Finally we made new natural nipple with 6 mm projection. We applied tattooing in the areola area with micropigmentation device after three months. Results: After ten months of follow-up periods, the nipple projection was stable and symmetric. The nipple projection was 3.1 mm, compared with 2.8 mm for the opposite nipple. Conclusion: Our experiences shows that this double opposing plow flap is a particularly useful and simple technique when there is a traverse scar crossing the center of the proposed nipple area.

Breeding for New Evergreen Dianthus Cultivar 'URI 2010-6' with Bright Red Flower Color (밝은 적색계의 상록성 패랭이꽃 신품종 'URI 2010-6' 육성)

  • Park, Kong-Young;Hwang, Hyeon-Jeong;Choi, Geun-Won
    • Horticultural Science & Technology
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    • v.33 no.1
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    • pp.143-148
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    • 2015
  • A new Dianthus cultivar 'URI 2010-6' was selected among F1 progenies from a cross between interspecific hybrid 'Evergreen Emerald' as the seed parent and D. chinensis ' Ruby' as the pollen parent. In 2007, the cross w as made, and the seedlings of $F_1$ progenies were obtained and investigated. After three rounds of characteristic evaluation from 2008 to 2010, a clone was selected and registered as 'URI 2010-6' at the Korea Seed and Variety Service (plant variety protection number: 4431) in 2011. The flower of 'URI 2010-6' is caryophyllaceous, single type, and mainly bright red (Red, N79C) with secondary white (White, N155C) on the edge or as spots on the petal. The flower has diameter of 2.7 cm and length of 0.8 cm. This cultivar blooms continuously about 150 d on average and may be used as evergreen plant during winter months.

A New Spray Chrysanthemum Cultivar, 'Noble Wine' with Good Color, Single Type and Bi-color Petals for Cut Flower (화색이 우수한 복색 홑꽃 스프레이국화 'Noble Wine' 육성)

  • Hwang, Ju Chean;Chin, Young Don;Chung, Yong Mo;Kim, Su Gyeong;Jeong, Byoung Ryong
    • FLOWER RESEARCH JOURNAL
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    • v.17 no.2
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    • pp.137-140
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    • 2009
  • A new spary chrysanthemum(Dendranthema grandiflorum) cultivar 'Noble Wine' was developed from a cross between 'SL03-01' and 'Artist Pink' by selection of seedlings and lines at the Flower Research Institute, Gyeongnam Agricultural Research and Extention Services(ARES) from 2003 to 2007. Its characteristics were investigated three times from 2005 to 2007 under condition of forcing culture in spring and retarding culture in autumn. The natural flowering time of 'Noble Wine' was October 26th, and yearround production was possible by day length treatment. Its capitulum was 5.4 cm in diameter, and had 21.6 ray florets and 28.5 head per stem in autumn. Its ray floret was red-purple with green central zone. 'Noble Wine' was about 45 days in spring, and 'Noble Wine' showed the vase life of 21.3 days in autumn. This cultivar was registered for a commercialization in 2007.

A New Spray Chrysanthemum Cultivar, 'Magic' with Bright Color, Vigorous, Single Type and Bi-color Petals for Cut Flower (선명한 화색과 초세가 우수한 복색 홑꽃 스프레이국화 'Magic' 육성)

  • Hwang, Ju Chean;Chin, Young Don;Chung, Yong Mo;Kim, Su Gyeong;Ro, Chi Woong;Jeong, Byoung Ryong
    • FLOWER RESEARCH JOURNAL
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    • v.18 no.3
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    • pp.211-215
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    • 2010
  • A new spray chrysanthemum(Dendranthema grandiflorum) cultivar 'Magic' was developed from a cross combination between 'Artist Pink' and 'SP0347' by selection of seedlings and lines at the Flower Research Institute, Gyeongnam Agricultural Research and Extension Services(ARES) from 2003 to 2007. Its characteristics were investigated three times from 2005 to 2007 under condition of forcing culture in spring and retarding culture in autumn. The natural flowering time of 'Magic' was October 26th, and year-round production was possible by day length treatment. Its capitulum was 6.1 cm in diameter, and had 31.9 ray florets and 11.7 head per stem in autumn. Its ray floret was white-purple with yellow green central zone. Days to flower of 'Magic' was about 43 days in spring, and 'Magic' showed the vase life of 20.6 days in autumn. This cultivar was registered for a commercialization in 2007.

A New Spray Chrysanthemum Cultivar, 'Moulin Rouge' with Bi-color and Single Petals for Cut Flower (절화용 복색 홑꽃 스프레이국화 'Moulin Rouge' 육성)

  • Hwang, Ju Chean;Chin, Young Don;Chung, Yong Mo;Park, Young Bae;Kim, Su Gyeong;Jeong, Byoung Ryong
    • FLOWER RESEARCH JOURNAL
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    • v.16 no.4
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    • pp.229-233
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    • 2008
  • A new spary chrysanthemum(Dendranthema grandiflorum) cultivar 'Moulin Rouge' was developed from a cross between 'Delmont' and 'Anjela' by selections of seedlings and lines at the Flower Research Institute, Gyeongnam Agricultural Research and Extension Services(ARES) from 2002 to 2006. Its characteristics were investigated three times from 2004 to 2006 under condition of forcing culture in spring and retarding culture in autumn. The natural flowering time of 'Moulin Rouge' was October 24th, and year-round production was possible by day length treatment. Its capitulum was 5.3 cm in diameter, and had 22.9 ray florets and 12.2 head per stem in autumn. Its ray floret was bi-color(yellow/orange) with green central zone. 'Moulin Rouge' was about 55 days to flower in spring, and showed the vase life of 21.7 days in autumn. This cultivar was registered for a commercialization in 2007.

A New Spray Chrysanthemum Cultivar, 'Serapina' with Good Shape, Single Type and Yellow Petals for Cut Flower (화형, 화색이 우수한 황색 홑꽃 스프레이국화 '세라피나' 육성)

  • Hwang, Ju Chean;Chin, Young Don;Chung, Yong Mo;Park, Young Bae;Kim, Su Gyeong;Jeong, Byoung Ryong
    • FLOWER RESEARCH JOURNAL
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    • v.16 no.3
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    • pp.200-204
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    • 2008
  • A new spary chrysanthemum(Dendranthema grandiflorum) cultivar 'Serapina' was developed from a cross between 'Relanse' and 'Yen' by selection of seedlings and lines at the Flower Research Institute, Gyeongnam Agricultural Research and Extention Services(ARES) from 2002 to 2006. Its characteristics were investigated three times from 2004 to 2006 under condition of forcing culture in spring and retarding culture in autumn. The natural flowering time of 'Serapina' was October 23th, and year-round production was possible by day length treatment. Its capitulum was 2.8cm in diameter, and had 43.4 ray florets and 28.9 head per stem in autumn. Its ray floret was yellow with green central zone. To flower in the short day condition, for 'Serapina' was about 46 days in spring, and 'Serapina' showed the vase life of 21.7 days in autumn. This cultivar was registered for a commercialization in 2007.