• Title/Summary/Keyword: Simulation Framework

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A Theoretical Framework of Strategic Decision Making Supporting Systems (전략의사결정지원시스템 개발을 위한 이론적 프레임워크에 대한 연구)

  • Kim, Yong Jin;Jin, Seung Hye;Lee, Seung Tae
    • Journal of Digital Convergence
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    • v.10 no.10
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    • pp.97-106
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    • 2012
  • In the past, executive managers made a decision based on personal experience and knowledge due to lack of the appropriate and timely information. With the development of information systems and technologies, efficiency and productivity of business operation has been enhanced. In this study, we propose a system design and architecture blue-print related to strategic decision making support system. The proposed system consists of 3 key parts; individual business feasibility test, business portfolio feasibility test, business portfolio management. The three key parts are comprised of 11 components to generate information and knowledge based on various data input from inside and outside of firm. This system is expected to provide objective and reliable output to users. In addition, the proposed strategic decision support system would help respond to a rapidly changing business environment.

Identification of Proapoptopic, Anti-Inflammatory, Anti-Proliferative, Anti-Invasive and Anti-Angiogenic Targets of Essential Oils in Cardamom by Dual Reverse Virtual Screening and Binding Pose Analysis

  • Bhattacharjee, Biplab;Chatterjee, Jhinuk
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.6
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    • pp.3735-3742
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    • 2013
  • Background: Cardamom (Elettaria cardamom), also known as "Queen of Spices", has been traditionally used as a culinary ingredient due to its pleasant aroma and taste. In addition to this role, studies on cardamom have demonstrated cancer chemopreventive potential in in vitro and in vivo systems. Nevertheless, the precise poly-pharmacological nature of naturally occurring chemo-preventive compounds in cardamom has still not been fully demystified. Methods:In this study, an effort has been made to identify the proapoptopic, anti-inflammatory, anti-proliferative, anti-invasive and anti-angiogenic targets of Cardamom's bioactive principles (eucalyptol, alpha-pinene, beta-pinene, d-limonene and geraniol) by employing a dual reverse virtual screening protocol. Experimentally proven target information of the bioactive principles was annotated from bioassay databases and compared with the virtually screened set of targets to evaluate the reliability of the computational identification. To study the molecular interaction pattern of the anti-tumor action, molecular docking simulation was performed with Auto Dock Pyrx. Interaction studies of binding pose of eucalyptol with Caspase 3 were conducted to obtain an insight into the interacting amino acids and their inter-molecular bondings. Results:A prioritized list of target proteins associated with multiple forms of cancer and ranked by their Fit Score (Pharm Mapper) and descending 3D score (Reverse Screen 3D) were obtained from the two independent inverse screening platforms. Molecular docking studies exploring the bioactive principle targeted action revealed that H- bonds and electrostatic interactions forms the chief contributing factor in inter-molecular interactions associated with anti-tumor activity. Eucalyptol binds to the Caspase 3 with a specific framework that is well-suited for nucleophilic attacks by polar residues inside the Caspase 3 catalytic site. Conclusion:This study revealed vital information about the poly-pharmacological anti-tumor mode-of-action of essential oils in cardamom. In addition, a probabilistic set of anti-tumor targets for cardamom was generated, which can be further confirmed by in vivo and in vitro experiments.

Data Sorting-based Adaptive Spatial Compression in Wireless Sensor Networks

  • Chen, Siguang;Liu, Jincheng;Wang, Kun;Sun, Zhixin;Zhao, Xuejian
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.10 no.8
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    • pp.3641-3655
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    • 2016
  • Wireless sensor networks (WSNs) provide a promising approach to monitor the physical environments, to prolong the network lifetime by exploiting the mutual correlation among sensor readings has become a research focus. In this paper, we design a hierarchical network framework which guarantees layered-compression. Meanwhile, a data sorting-based adaptive spatial compression scheme (DS-ASCS) is proposed to explore the spatial correlation among signals. The proposed scheme reduces the amount of data transmissions and alleviates the network congestion. It also obtains high compression performance by sorting original sensor readings and selectively discarding the small coefficients in transformed matrix. Moreover, the compression ratio of this scheme varies according to the correlation among signals and the value of adaptive threshold, so the proposed scheme is adaptive to various deploying environments. Finally, the simulation results show that the energy of sorted data is more concentrated than the unsorted data, and the proposed scheme achieves higher reconstruction precision and compression ratio as compared with other spatial compression schemes.

Optimization-based method for structural damage detection with consideration of uncertainties- a comparative study

  • Ghiasi, Ramin;Ghasemi, Mohammad Reza
    • Smart Structures and Systems
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    • v.22 no.5
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    • pp.561-574
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    • 2018
  • In this paper, for efficiently reducing the computational cost of the model updating during the optimization process of damage detection, the structural response is evaluated using properly trained surrogate model. Furthermore, in practice uncertainties in the FE model parameters and modelling errors are inevitable. Hence, an efficient approach based on Monte Carlo simulation is proposed to take into account the effect of uncertainties in developing a surrogate model. The probability of damage existence (PDE) is calculated based on the probability density function of the existence of undamaged and damaged states. The current work builds a framework for Probability Based Damage Detection (PBDD) of structures based on the best combination of metaheuristic optimization algorithm and surrogate models. To reach this goal, three popular metamodeling techniques including Cascade Feed Forward Neural Network (CFNN), Least Square Support Vector Machines (LS-SVMs) and Kriging are constructed, trained and tested in order to inspect features and faults of each algorithm. Furthermore, three wellknown optimization algorithms including Ideal Gas Molecular Movement (IGMM), Particle Swarm Optimization (PSO) and Bat Algorithm (BA) are utilized and the comparative results are presented accordingly. Furthermore, efficient schemes are implemented on these algorithms to improve their performance in handling problems with a large number of variables. By considering various indices for measuring the accuracy and computational time of PBDD process, the results indicate that combination of LS-SVM surrogate model by IGMM optimization algorithm have better performance in predicting the of damage compared with other methods.

Rank-based Formation for Multiple Robots in a Local Coordinate System (지역 좌표에서 랭크기반의 다개체 로봇 포메이션 제어)

  • Jung, Hahmin;Kim, Dong Hun
    • Journal of the Korean Institute of Intelligent Systems
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    • v.25 no.1
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    • pp.42-47
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    • 2015
  • This paper presents a rank-based formation for multiple agents based on potential functions, where the proposed method uses the relative position of two neighboring agents. The conventional formation scheme of multiple systems requires communication between agents and a central computer to get the positions of all multiple agents. In the study, differently from previous studies, the formation scheme uses the relative position of two neighboring agents in a local coordinate system. In addition, it introduces a singular agent association that considers only the relative position between an agent and its neighboring agents, instead of multiple associations among all information about all agents. Furthermore, the proposed framework explores the benefits of different formation types. Extensive simulation results show that the proposed approach verifies the viability and effectiveness of the proposed formation.

Adaptive Sidelobe Blanker for Interference Environment (간섭 환경에 강인한 적응형 부엽차단기)

  • Yang, Eunjung;Han, Iltak;Song, Junho;Lee, Heeyoung;Yeom, Dongjin
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.26 no.3
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    • pp.317-325
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    • 2015
  • In an interference environment, adaptive sidelobe blanking(adaptive SLB: ASB) algorithm effectively cancels the high-duty cycle jammer and blocks the sidelobe signals without the auxiliary antenna. The adaptive SLB for the linearly constrained minimum variance (LCMV) is proposed in this paper. In the proposed scheme, the interference covariance matrix is modified to satisfy the direction constraints of LCMV and the normalized output can be obtained to block sidelobe signals. As the LCMV can be represented as a generalized sidelobe canceller(GSC) form, which is the general framework of various adaptive beamforming(ABF) algorithms, the proposed adaptive SLB can be applied to various ABF methods. The performance of the proposed method is verified through simulation and analysis.

Efficient Kernel Integrity Monitor Design for Commodity Mobile Application Processors

  • Heo, Ingoo;Jang, Daehee;Moon, Hyungon;Cho, Hansu;Lee, Seungwook;Kang, Brent Byunghoon;Paek, Yunheung
    • JSTS:Journal of Semiconductor Technology and Science
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    • v.15 no.1
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    • pp.48-59
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    • 2015
  • In recent years, there are increasing threats of rootkits that undermine the integrity of a system by manipulating OS kernel. To cope with the rootkits, in Vigilare, the snoop-based monitoring which snoops the memory traffics of the host system was proposed. Although the previous work shows its detection capability and negligible performance loss, the problem is that the proposed design is not acceptable in recent commodity mobile application processors (APs) which have become de facto the standard computing platforms of smart devices. To mend this problem and adopt the idea of snoop-based monitoring in commercial products, in this paper, we propose a snoop-based monitor design called S-Mon, which is designed for the AP platforms. In designing S-Mon, we especially consider two design constraints in the APs which were not addressed in Vigilare; the unified memory model and the crossbar switch interconnect. Taking into account those, we derive a more realistic architecture for the snoop-based monitoring and a new hardware module, called the region controller, is also proposed. In our experiments on a simulation framework modeling a productionquality device, it is shown that our S-Mon can detect the rootkit attacks while the runtime overhead is also negligible.

Study on the Characteristics of Infinite Slope Failures by Probabilistic Seepage Analysis (확률론적 침투해석을 통한 무한사면 파괴의 특성 연구)

  • Cho, Sung-Eun
    • Journal of the Korean Geotechnical Society
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    • v.30 no.10
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    • pp.5-18
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    • 2014
  • Many regions around the world are vulnerable to rainfall-induced slope failures. A variety of methods have been proposed for revealing the mechanism of slope failure initiation. Current analysis methods, however, do not consider the effects of non-homogeneous soil profiles and variable hydraulic responses on rainfall-induced slope failures. In this study, probabilistic stability analyses were conducted for weathered residual soil slopes with different soil thickness overlying impermeable bedrock to study the rainfall-induced failure mechanisms depending on the soil thickness. A series of seepage and stability analyses of an infinite slope based on one-dimensional random fields were performed to consider the effects of uncertainty due to the spatial heterogeneity of hydraulic conductivity on the failure of unsaturated slopes due to rainfall infiltration. The results showed that a probabilistic framework can be used to efficiently consider various failure patterns caused by spatial variability of hydraulic conductivity in rainfall infiltration assessment for a infinite slope.

A Utility-Based and QoS-Aware Power Control Scheme for Wireless Body Area Networks

  • Li, Yanjun;Pan, Jian;Tian, Xianzhong
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.10 no.9
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    • pp.4188-4206
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    • 2016
  • Power control is widely used to reduce co-channel interference in wireless networks and guarantee the signal-to-interference plus noise ratio (SINR) of ongoing connections. This technique is also effective for wireless body area networks (WBANs). Although achieving satisfactory SINR is important for WBAN users, they may not be willing to achieve it at arbitrarily high power levels since power is a scarce resource in WBANs. Besides, for WBANs with different purposes, the QoS requirements and concern about the power consumption may be different. This motivates us to formulate the power control problem using the concepts from microeconomics and game theory. In this paper, the QoS objective is viewed as a utility function, which represents the degree of user satisfaction, while the power consumption is viewed as a cost function. The power control problem consequently becomes a non-cooperative multiplayer game, in which each player tries to maximize its net utility, i.e., the utility minus the cost. Within this framework, we investigate the Nash equilibrium existence and uniqueness in the game and derive the best response solution to reach the Nash equilibrium. To obtain the optimal transmission power in a distributed way, we further propose a utility-based and QoS-aware power control algorithm (UQoS-PCA). Tunable cost coefficient in UQoS-PCA enables this scheme to be flexible to satisfy diverse service requirements. Simulation results show the convergence and effectiveness of the proposed scheme as well as improvements over existing algorithm.

Day-to-day dynamics model based on consistent travel time perception behavior (운전자의 일관성 있는 통행시간 인지 행태에 기반한 일별 동적 모형)

  • Yang, In-Chul;Chung, Youn-Shik
    • International Journal of Highway Engineering
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    • v.13 no.2
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    • pp.195-202
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    • 2011
  • This study develops a day-to-day dynamics modeling framework, incorporating a consistent drivers' travel time perception behavior and traffic information provision. Descriptive traffic information is updated and provided to the subscribers making a final decision on route choice. Nonsubscribers(not equipped any information devices) are assumed to obtain daily traffic information from their experience or friends or other public agencies. Drivers' route choice behavior is modeled based on boundedly-rational behavior rules. A microscopic traffic simulation model is adopted to evaluate the network system performance. Numerical experiments on a real world network have demonstrated the convergent property of the proposed model and the effectiveness of the consistent perception model.