• The Bulletin of The Korean Astronomical Society
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• v.35 no.1
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• pp.48.1-48.1
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• 2010

Four of nine exoplanets found by microlensing were detected by the resonant caustic, which represents the merging of the planetary and central caustics at the position when the projected separation of a host star and a bounded planet is s~1. One of the resonant caustic lensing events, OGLE-2005-BLG-169, was a caustic-crossing high-magnification event with A_max ~800 and the source star was much smaller than the caustic, nevertheless the perturbation was not obviously apparent on the light curve of the event. In this paper, we investigate the perturbation pattern of the resonant caustic to understand why the perturbations induced by the caustic do not leave strong traces on the light curves of high-magnification events despite a small source/caustic size ratio. From this study, we find that the regions with small magnification excess around the center of the resonant caustic are rather widely formed, and the event passing the small-excess region produces a high-magnification event with a weak perturbation that is small relative to the amplification caused by the star and thus does not noticeably appear on the light curve of the event. We also find that the positive excess of the inside edge of the resonant caustic and the negative excess inside the caustic become stronger and wider as q increases, and thus the resonant caustic-crossing high-magnification events with the weak perturbation occur in the range of q $\leq$ 10-4. We determine the probability of the occurrence of events with the small excess $|\varepsilon|{\leq}3%$ in high-magnification events induced by a resonant caustic. As a result, we find that for the Earth-mass planets with a separation of ~2.5 AU the resonant caustic high-magnification events with the weak perturbation can occur with a significant frequen.

• Journal of Korean Academy of Nursing
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• v.30 no.2
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• pp.259-271
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• 2000

This study was attempted to explore meaning in life and it's relationship to problematic life events, health status and depression among older people. 198samples of elderly were over the age 60 (mean age=70.06) conveniently selected in Seoul, Korea. The data were collected through questionaires by interview with subjects from April, 1, 1999 to May 30, 1999. The research instuments were the main framework in the experiment. They involved meaning fulfillment and problematic life events which were developed by Burbank (1988) and short form geriatric depression scale(Sheikh & Yesavage, 1986). The data were analysed by SAS Program. The results are followed; 1. 172 lists were given out and had objects that would bring meaning to one's life. They were categrized as wishing for offsprings' prosperity, their relation with their grand-children, marriage of their offspring, health of family members, strong family ties, caring for the family, relation with husband, health for self, religious activity, helping others, individual hobbies, needs for growth such as writing, education, relationships with friends and personal achievements. In the end, 50% of total list dealt with in the relationship with their family members. 2. The mean fulfillment of the subjects was 38.31(SD=13.58) with a range of 12-60. The degree fulfillment varied according to the subjects' characteristics such as age group(F=4.44, 0P=.0008), education status (F=6.44, P=.0001), economic status (F=10.27, P=.0001), marrital status (F=9.12, P=.0002) and religious background (F=3.68, P=.006). 3. According to the pearson correlation, analysis significant variables were found between meaning fulfillment and health(r=.47, P=.0001), depression and the number of problematic life events for a life time (r=.147, P=.04), the stress score of problamatic life events for the past one year and the stress score of problematic life events for a life time was r=.43, P=.002, meaning fulfillment and the stress score of problamatic life events r=-.26, P=.04, depression and meaning fulfillment r=-.70, P=.0001 and depression and health r=-.521, P=.0001. 4. According to multiful regression analysis, depression was found as a most predictable variable for health(F=12.51, P=.001).

• Journal of the Korea Academia-Industrial cooperation Society
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• v.10 no.7
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• pp.1642-1647
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• 2009

Changes in aerosol characteristics during 2006 ${\sim}$2008 Asian dust events in Cheoan were investigated by measuring mass, ion and elemental concentrations of fine and coarse particles. The average mass concentrations of daily TSP, PM10, PM2.5 were 214.9, 160.3, and 95.9${\mu}\;g/m^3$during Asian dust events, which were 3.08, 2.58, and 1.95 times higher than Non-asian dust events. The maximum concentrations of TSP, PM10, and PM2.5 were 850.1, 534.4, and 233.3${\mu}\;g/m^3$, which were 12.19, 8.60, and 4.76 times higher, respectively. Increases in ion concentrations were not significant during Asian dust events, but elemental concentrations including soil components such as Fe, Al, Ti increased by 17.1 and 43.4 times for fine and coarse particles, respectively. The results clearly indicate that metallic components from soil constituents were the major components in Asian dusts sampled at Cheonan.

• Korean Journal of Clinical Pharmacy
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• v.31 no.3
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• pp.188-197
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• 2021

Objective: PD-1 inhibitors have demonstrated improved health outcomes in cancer patients. PD-1 inhibitors are well-tolerated and associated with immune-related adverse events. The objectives of this study are to analyze use patterns of PD-1 inhibitors in patients with cancer and to investigate the incidence of thyroid-related adverse reactions in patients treated with PD-1 inhibitors. Methods: The study included patients who had been administered PD-1 inhibitors (either nivolumab or pembrolizumab) at the Samsung Medical Center between October 1, 2016 and June 30, 2017. Data was collected from electronic medical records and tested using Mann-Whitney tests and Chi-Square tests for statistical significance. Associations between PD-1 inhibitors and incidence of adverse events were tested using Cox regression for age, gender, BMI, ECOG PS and medication. Results: Two hundred fifteen patients were identified as eligible for analyses. Thyroid-related adverse events occurred in 20% of patients (n=43). Thyroid function tests (TFTs) was performed in 109 patients (50.7%). Positive results of PD-L1 testing were found in 53.2% of the 94 patients who had the test. Approved doses of nivolumab (3 m/kg) and pembrolizumab (200 mg) were administered in 70.4% and 53% of patients, respectively. The analysis of risk factor of thyroid-related adverse reaction did not show statistically significant differences (Cox regression). Conclusion: Thyroid-related adverse events are common in patients treated with PD-1 inhibitors and hypothyroidism is the most frequent adverse reaction. Routine TFTs monitoring is strongly recommended to evaluate thyroid function in real-world clinical practice.

• Journal of the Korean Data Analysis Society
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• v.20 no.6
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• pp.3169-3183
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• 2018

Based on the affective event theory, the purpose of the study is to examine the effect of the individual difference regulatory focus on the process in which the work events affect job engagement under organizational circumstances. To this end, 232 financial workers were surveyed on positive events, positive affects, regulatory focus and job engagement. The results of the analysis are as follows. First, the positive events generated positive affects and showed positive influence on job engagement. Second, the effect of positive affects on job engagement has been shown to be discriminatory depending on the level of regulatory focus. The higher the level of promotion focus, the stronger the effect on job engagement of positive affects, and the higher the level of prevention focus, the weaker the effect on job engagement of positive affects. Third, the moderated mediated effect was found to be significant only in the prevention focus. The magnitude of indirect effects on job engagement by positive events was found to be weakened when the prevention focus was high. Finally, the implications and future research issues were discussed.

• Journal of Neurogastroenterology and Motility
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• v.25 no.3
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• pp.387-393
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• 2019

Background/Aims Delayed gastric emptying (GE) is associated with high morbidity and mortality in subjects with diabetes. The aim of this study is to investigate associations between GE time and the major cardiovascular events (coronary heart diseases and ischemic stroke) in diabetic subjects with upper gastrointestinal (UGI) symptoms. Methods Among 259 subjects with chronic UGI symptoms who underwent gastric emptying study (GES) over 13 years, 122 diabetic subjects without gastric surgery and/or rapid GE were enrolled in this study. We also gathered data about baseline demographics, clinical characteristics, estimated GE half-time (GE T½) and incidence of cardiovascular events following GES. Results The mean age of subjects was 64.0 ± 17.4 years. There were 86 women and 104 subjects with type 2 diabetes. There were 52 (42.6%) subjects with normal GE, 50 (41.0.%) subjects with mild delayed GE, and 20 (16.4%) subjects with marked delayed GE. During follow-up (median, 207 weeks), cardiovascular events occurred in 7 (13.5%) subjects with normal GE, 4 (8.0%) subjects with mild delayed GE and 7 (35.0%) subjects with marked GE (P = 0.015). Univariate analysis showed that GE T½ was significantly associated with incidence of cardiovascular events (crude OR, 1.74; 95% CI, 1.12-2.69; P = 0.014). In a multivariate model, association between GE T½ and incidence of cardiovascular events remained statistically significant after adjustment for baseline characteristics and comorbidities (adjusted OR, 1.94; 95% CI, 1.21-3.12; P = 0.006). Conclusion A delay of GE was associated with an increased incidence of cardiovascular events in diabetic subjects with chronic UGI symptoms.

• The Journal of Korean Medicine
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• v.42 no.1
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• pp.46-58
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• 2021

Objectives: The purpose of this study is to report weight changes and analyze adverse events in diabetic patients with Gamitaeeumjowee-Tang for weight loss. Methods: A retrospective chart review of weight change and adverse events was performed during the 10-week weight loss program using Gamitaeeumjowee-tang with low-calorie diets for diabetics(n=61). Weight and BMI changes were compared before and after the program and calculated the percentage of people who lost more than 5% of their weight, also identified whether subjects felt satiated or not. Adverse events were evaluated in terms of causality, severity and system-organ classes. Results: After 10-week weight loss program, significant weight loss (5.9±2.32kg, 7.73% reduction from baseline) and BMI reduction (2.9±0.86) were reported (n=61). Those who lost more than 5 percent of their body weight accounted for 88.5%, and also 88.5% of the participants felt full to help control their appetite. In assessing the causality of adverse events, 'Unlikely' was the most common (66%) and in severity evaluations, almost all symptoms were mild. Insomnia was the most frequently reported during the first 8 weeks, and constipation was reported the most afterwards. Conclusions: A combination of Gamitaeeumjowee-tang and low-calorie diets for 10 weeks appears to help weight reduction without serious adverse events in diabetic patients. Future well-designed prospective clinical studies testing the effectiveness and safety of this weight loss program are warranted.

• The Journal of the Convergence on Culture Technology
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• v.9 no.5
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• pp.391-395
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• 2023

There are countless possibilities lying ahead of us, and while predicting the future may be challenging, it does not render the act of forecasting meaningless. Predicting various possibilities allows us to be flexible in coping with unforeseen circumstances. This study was conducted to explore extreme events (X-events) in the population sector in South Korea. To achieve this, focus group interviews were conducted with 32 emergency planning officers in government and public services. Based on these interviews, significant research findings were derived, indicating that population issues such as population decline and aging could have substantial impacts on various fields, including the economy and national defense. With this study as a catalyst, we anticipate a more active discussion and discourse on X-events that could occur in our society.

• Journal of Korean Academy of Nursing
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• v.10 no.1
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• pp.57-64
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• 1980

The purpose of the study was to find out the relationship between experienced stressful events and its coping behavior within mentally wellness and illness, and to define the effective coping method under the stressful situation. By doing so, during the period of April, 1978- to March, 1979 the objects of this study were 100 persons who were under the psychiatric facilities in their first hospitalization, and who were registered in psychiatric out patient department in the form general hospitals located at Seoul selected as a experimental group. As a control group 100 persons who never experienced psychiatric treatment who were not under the current medical treatment, and who were tarring appropriate social roles in their community were selected, and in both groups utilized questimaires for Social Readjustment Pating Scale and Coping Scale. This study was tested by X$^2$ examinationand by F-ratio（analysis of variance). Results were as follows : Hypothesis 1. The actually experienced life events were expected to be higher in the experimental group than in the control group, but they did not show the significant difference between the groups.（ p >0.05) Thus hypothesis 1 was rejected. Hypothesis : 2. The stress scores were expected to be higher in the experimental group than in the control group, and also did show the significant difference between the groups ( p< 0.05）. Therefore hypothesis 2 was supported. Hypothesis 3. The non-effective coping behavior were expected to be higher in the experimental group than in the control group, and also did show the significant difference between the two groups(p < 0.001). Also hypothesis 3 was supported. Hypothesis 4 . The higher stress score groups (above 250 LCU ) were expected to utilize non.effective coping method more frequently than in the lower stress score groups (below 249 LCU ), and not only they showed high in utilizing non-effective coping method but also showed high in utililzing effective coping method. Thus hyphothesis 4 was partially supported. (p < 0.001) The following are drawn out based on the result of this study that the stress scores were higher, and more utilized non-effective coping method in the emotionally disturbances than in the emtionally healthies.

• Ocean and Polar Research
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• v.23 no.4
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• pp.361-376
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• 2001

The characteristics of SST variability in the East Sea are analyzed using NOAA/AVHRR weekly SST data with about $0.18^{\circ}{\times}0.18^{\circ}$ resolution ($1981{\sim}2000$) and reconstructed historical monthly SST data with $2^{\circ}{\times}2^{\circ}$ resolution $(1950{\sim}1998)$. The distinct feature of wintertime SST is high variability in the western and eastern parts of $38^{\circ}{\sim}40^{\circ}$ latitudinal band, which are the northern boundary of warm current in the East Sea during winter. However, summertime SST exhibits variability with similar magnitude in the entire region of the East Sea. The analysis of remote correlation also shows that SST in the East Sea is closely correlated with that in the region of Kuroshio in winter, but in summer is related with that in the western and eastern regions of the same latitudes. From these results it is postulated that the SST variability in the East Sea may be related with the variations of East Korean Warm Current and Tsushima Warm Current in winter, but in summer probably with the variations of atmospheric components. In the analysis of ENSO related SST anomaly, a significant negative correlation between SST anomalies in the East Sea and SST anomalies in the tropical Pacific is found in the months of August-October (ASO). The SST in the ASO period shows more significant cooling in E1 $Ni\~{n}o$ events than warming in La $Ni\~{n}a$ events. Also, the regional analysis shows by the Student's t-test that the negative SST anomalies in the E1 $Ni\~{n}o$ events are more significant in the southwestern part of the East Sea.