• Asian-Australasian Journal of Animal Sciences
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• v.14 no.9
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• pp.1267-1271
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• 2001

The objective of this study was to examine the significance of feeding induced hypovolemia (decrease in plasma volume) in controlling the feed intake of goats fed on dry feed. In order to alleviate hypovolemia with feeding, a 2 h intravenous infusion (16-18 ml/min) of artificial saliva or mannitol solution was begun 1 h prior to feeding and continued until 1h after the start of the 2 h feeding period. In comparison with no infusion (NI), cumulative feed intake was increased by 41% with artificial saliva infusion (ASI) and by 45% with mannitol infusion (MI) by the completion of the 2 h feeding period. Both infusion treatments (ASI and MI) were significantly different (p<0.05) from the NI treatment in terms of the cumulative feed intake. The cumulative feed intake between the ASI and MI treatments was not significantly different (p>0.05). No infusion treatment (NI) had the lowest cumulative feed intake (929 g DM), whereas MI had the highest (1345 g DM), after completion of the 2 h feeding period. Generally, infusion treatments also increased the rate of eating at all time points after feeding was commenced. Following the first 30 mins of feeding, the rate of eating decreased sharply, and subsequently declined gradually in all treatments. Compared to the NI, both ASI and MI significantly (p<0.05) decreased thirst level (water intake for 30 mins after the completion of the 2 h feeding period) by approximately 13%. However, the thirst level caused by ASI and MI was not significantly different (p>0.05). Both ASI and MI decreased the plasma concentrations of osmolality and total protein, and hematocrit at 1 h after infusion. The results suggested that the thirst sensation in the brain could be produced by feeding induced hypovolemia. Moreover, the results indicate that hypovolemia is one of the factors controlling the feed intake of goats fed on dry feed.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.9
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• pp.5473-5476
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• 2013

Background: In our study, the LDH, albumin, hemoglobin, neutrophile, thrombocyte, lymphocyte counts and prognostic significance of neutrophile-lymphocyte and thrombocyte-lymphocyte ratios in NSCLC derived from these counts obtained during regular examinations of patients were examined. Materials and Methods: Histopathologically diagnosed non-small-cell-lung cancer patients between 2008 and 2010 were included in the study. Before the treatment, full blood count including routine lymphocyte count, blood biochemistry examinations including liver (AST, ALT, total protein, Albumin), LDH and kidney (BUN, Cre) function tests were performed. Results: A total of 156 patients, 76 of whom (48.7%) were female and 80 of whom (51.3%) were male were included. Mean hemoglobin level was determined as 12. Overall survival was found to be significantly dependent on whether patients were anemic or not (p: 0.005). Mean LDH level was determined as 233.4. There was nosurvival difference between patients with and without high LDH (p: 0.532). In patients where NLR showed systemic inflammatory response, overall survival was 10.8 months whereas this duration was 19.6 months in patients where the systemic inflammatory response was negative (p: 0.012). In patients where TLR showed systemic inflammatory response, overall survival was 13.6 months whereas this duration was 21.9 months in patients where the systemic inflammatory response was negative (p: 0.04). Conclusions: Molecular methods have been changing rapidly in today's world and they manage the treatment besides defining the prognosis of patients. However, easily accessible and cheap laboratory parameters should be considered in the prognosis of patients besides these new methods.

• The Korea Journal of Herbology
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• v.30 no.3
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• pp.25-34
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• 2015

Objectives : This study was performed to investigate the efficacy and safety of the Mulberry Extract Complex in a placebo-controlled randomized clinical trial and animal study on degenerative arthritis. Methods : Animal study: Mulberry Extract Complex is composed of extracts of mulberry (Morus alba L.) fruit, mulberry leaves and black beans (Glycine max (L.) Merr.). To evaluate the serum level of interleukin-2, interferon-$\gamma$, and prostaglandin E2, an animal model of degenerative arthritis induced by monosodium iodoacetate was employed. Clinical study: The efficacy index (VAS, K-WOMAC) was compared among patients with symptoms of degenerative arthritis before and after Mulberry Extract Complex ingestion as well as the one in groups. Evaluations of the improvement by the subjects and by doctor assessment were also performed. Results : Animal study: Mulberry Extract Complex reduced the serum level of interferon-$\gamma$ and prostaglandin E2 in an animal model with degenerative arthritis. Clinical study: The VAS change showed statistical significance in the experimental groups after 4 weeks (PP set) and 8 weeks (ITT set) of ingestion. When the K-WOMAC was analyzed using a modified ITT set to determine the effectiveness, statistically significant results were obtained in the fields of pain & symptom within the Mulberry Extract Complex group as well as between the Mulberry Extract Complex and placebo groups after 8 weeks of ingestion. Results from the improvement evaluation by subjects and the assessment of improvement by doctors showed statistical significance in the experimental groups (PP set) after 8 weeks. Conclusions : Mulberry Extract Complex could be useful for the improvement of various symptoms of degenerative arthritis based on its anti-inflammatory activity and its reduction of VAS and K-WOMAC pain scores.

• Journal of Pharmacopuncture
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• v.6 no.1
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• pp.16-17
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• 2003

Objectives : This study was designed to evaluate effects of 'Soyeum' on cancer patients accompanied by pain. Materials and Methods : We retrospectively analyzed the medical records of 9 patients accompanied by pain who had been injected with 'Soyeum' for over 14 days continuously in East-West Cancer Center of Oriental Hospital of Daejeon University from June 2002 through august 2002. Results : The statistical significance between the pre-treatment and post-treatment results (Changes of Cytokine Level, QOL, BPQ and Pain relief after pain management) were analyzed. Analysis of cytokines (IL-12, IFN- ) level showed that the percentage of increase of lL-12 is $60\%$, IFN- is $60\%$. Analysis of QOL showed that the percentage of maintenance and improvement is $77.8\%$. $55.5\%$ of the patients reported a 'worst pain' intensity score of 3 or greater, $44.5\%$ reported a 'least pain' intensity score of 2 or greater, and $66.7\%$ reported 'average pain' intensity score of 2 or greater. $33.3\%$ of the patients were in pain at the time of interview and $22.2\%$ had a current intensity score of 2 or greater. Analysis of pain relief after pain management showed that the percentage of pain relief score of 2 and 3 is $55.6\%$. The data was expressed as Mean SE by using descriptive statistics. Statistical significance examined by using paired t-test. Conclusions : It is suggested that 'Soyeum' has effects on pain of cancer patients, also expected that 'Soyeum' is useful to improve immunoactivity and for cancer patients

• Journal of Distribution Science
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• v.17 no.9
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• pp.117-125
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• 2019

Purpose - We investigate how to increase consumer incentives to buy public offering funds, resulting in activating the public offering fund market. In particular, this study aims to find ways to expand diversity and to improve efficiency of public offering fund. The public fund market of Korea has been stagnant in recent years. However, the public offering fund market plays a very significant role in terms of consumer welfare. Since only a few wealthy investors can participate in the private equity market, the stagnation in the public offering fund market usually reduces the opportunity of consumer's buying funds thus ultimately affecting their future wealth. Research design, data, and methodology - To attain our purpose, the 'factor-based portfolio strategy' has been considered. It is an alternative portfolio strategy, which composites the advantages of the passive management and active management. For our empirical anaylsis, we used global stock distribution market data over the period of 1991 and 2016. Then we constructed portfolios based on firm-size, firm-value, and momentum. Finally, a regression model was set, then hypotheses were tested, analyzing the performances. Results - First, among the 15 factor-based portfolios of global, Europe, Asia-Pacific(ex Japan), US and Japan, in eight portfolios, positive excess returns are observed at 5% significance level. Further, there is another portfolio with positive excess return at 10% significance level. Second, most of the portfolios with significant excess performance show positive relationship with the market portfolio. However, the firm-value based portfolio in Asia-Pacific region shows no relationship, and the firm-value based portfolio in US shows negative relationship. Third, we confirmed that the two firm-value factor portfolios in Asia-Pacific region and US, not having positive relationship with market portfolio, provide significant excess returns. Conclusions - In this paper, we provide empirical evidences supporting that the factor-based portfolios expand the diversity of funds and improve the efficiency of investment performance. However, there is no guarantee that the efficiency will continue in the future. In addition, various constraints and costs must be considered. Nevertheless, our novel findings in the advanced financial market such as US and Asia-Pacific are very interesting and offers important implications.

• Journal of Korean Society of Transportation
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• v.25 no.1 s.94
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• pp.73-79
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• 2007

This study deals with traffic accidents at the ramps of trumpet interchanges. The purpose of the study is to analyze the relations between tke turning direction of ramps (and combinations with other factors) and traffic accidents. In Pursuing this analysis, this study gives particular attention to the combination of turning direction and grade and the combination of turning direction and radius of curvature in the case of the trumpet interchange ramps. The null hypothesis tests show that the average accident number and average accident rate ate rejected at the 90% and 95% significance level respectively Also. the null hypothesis tests show that the combinations or turning direction and Evade as well as turning direction and radius are all rejected at the 95% significance level. In summary, right turn movements ate more dangerous than left turns on the trumpet interchange vamps. Also, ramps with a right turn and up grade or with a left turn and radius more than 200m have more traffic accident Potential than other types of ramps.

• Journal of Chest Surgery
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• v.33 no.8
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• pp.669-675
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• 2000

Background: Tuberculous pleurisy is the leading cause of pleural effusion in Korea. And differential diagnosis of tuberculous pleurisy with other cause is clinically very important. Traditional diagnostic methods such as routine analysis of pleural fluid, staining for acid-fast bacilli or pleural biopsy have major inherent limitaion. This study was designed to evaluate the significance of pleural fluid polymerase chain reaction(PCR) and adenosine deaminase (ADA) activity in early diagnosis of tuberculous pleurisy. Material and Method: Between March 1996 and July 1997, 198 patients with pleural effusion reviewed retrospectively. The study group included 112 cases with tuberculous effusion and 86 cases with non-tuberculous effusions, whose diagnoses were confirmed by pleural biopsy, microbiological methods, or cytology. We compared the results of PCR and pleural fluid levels of ADA between tuberculous and non-tuberculous effusions. Result: Mean age was 47.54$\pm$19.52 years(range 2 to 85 years). The positive rate of PCR was significantly higher in tuberculous group than non-tuberculous group(p<0.05). The sensitivty, specificity, positive predictive value(PPV), and negative predictive value(NPV) for PCR were 31.7, 90.9, 83.0, and 48.8%, respectively. Mean ADA activity was significantly higher in tuberculous group than non-tuberculous group(83.2 U/L vs 49.8 U/L)(p<0.05). With diagnostic thresholds of 40 U/L, the sensitivity, specificity, PPV, and NPV of ADA for tuberculosis were 75.9, 70.9, 77.3, and 69.3% respectively. At a level of 70 U/L, the sensitivity, specificity, PPV, and NPV of ADA for tuberculosis were 70.1, 75.9, 82.9, and 60.3% respectively. Conclusion: PCR is very highly specific, but less sensitive methods in diagnosis of tuberculous pleurisy. But ADA level of pleural fluid has acceptable sensitivity and specificity in diagnosis of tuberculous pleurisy. ADA activity is more useful test in the evaluation of pleural effusions.

• Journal of Korean Physical Therapy Science
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• v.9 no.1
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• pp.53-59
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• 2002

This study is research for effect of the involved lower limb weight bearing training on symmetrical weight supporting rate improvement by practicing involved lower limb weight bearing training of three weeks period to improve standing equilibrium problem with asymmetric weight supporting rate of hemiplegia. In result of the study, it has shown that P-value incase of involved supporting rate is lower than level of significance $\alpha$<.05 and mean improvement rate of experienced group is higher in comparison with controlled group and experienced group. In changing quantity of involved maximum supporting rate, P-value is .26 and higher than level of significance $\alpha$<.05, and so it did not show significant difference statistically. But in case of experienced group between pre and post-test, involved side supporting rate and involved side maximum supporting rate showed significant improvement in all. In comparison of relative characteristic training effect difference, it was shown that train-learning effect on case of 40-60 years old, hemorrhagic patient and standard body bun of patient is valuable, which showed significant improvement in case of paralytic side and disease period, it did not show significant difference on excercise learning effect in two above cases. In the above result, we can say that continuous weight bearing training on the involved lower limb for three weeks period help improve the involved side supporting rate of hemiplegia. Accordingly, the weight bearing training on the involved lower limb is training method that patient can easily train with simple guidance of therapists, without being special expensive equipment. Furthermore it can be helpful to establish home therapeutic plan for hemiplegia through education of a patron.

• Journal of the Korean Society for Library and Information Science
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• v.33 no.2
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• pp.119-139
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• 1999

It Is the purpose of this research to analyse users' understanding how keyword and boolean search work in SELIS(SEoul Women's University Library and Information System) OPAC. Results of analyses of the subject, SELIS OPAC system processing, are: comprehension percentage of keyword extraction is $67(22.48\%)$ out of total 298 persons, no comprehension is $231(77.52\%)$ understanding of boolean OR In keyword search appears $115(22.48\%)$ out of 297, no understanding does $182(77.52\%)$ : comprehension of boolean AND is $98(33.11\%)$ out of 296, no understanding appears $198(66.89\%)$ understanding of using boolean and symbols is $109(36.49\%)$ out of 285, no understanding is $181(63.51\%)$ which Is lower percentage generally. And in SELIS OPAC system, in Intentional analyses to see any difference in understanding of keyword search between experience of keyword search or no, It shows no difference in interrelation $5\%$ level of significance, but In boolean search it does in interrelation $5\%$ level of significance.

• Journal of the Korean Society of Hazard Mitigation
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• v.9 no.6
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• pp.17-30
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• 2009

In this study, the existence of possible deterministic longterm trend of precipitation amount, monthly maximum precipitation, rain day, the number of rain day greater than 20mm, 30mm, and 80mm was analyzed using the Mann-Kendall rank test and the data from 62 stations between 1905 and 2004 in South Korea. Results indicate that the annual and monthly rainfall amount increases and the number of rain days which have more than 80mm rainfall a day, increases. However the number of rain days decreases. Also, monthly trend analysis of precipitation amount and monthly maximum precipitation increases in Jan., May, Jun., Jul., Aug., and Sep. and they decrease in Mar., Apr., Oct., Nov., and Dec. Monthly trend of the number of rain day greater than 20mm, 30mm, and 80mm increases in Jun., Jul., Aug., and Sep. However results of Mann-Kedall test demonstrated that the ratio of stations, which have meaningful longterm trend in the significance level of 90% and 95%, is very low. It means that the random variability of the analyzed precipitation related data is much greater than their linear increment.