• Title/Summary/Keyword: Significance Level

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Treatment Result of Foot Amputation Stratified by Level of Amputation (절단 위치에 따른 족부 절단술의 치료 결과)

  • Kim, Ji Hoon;Ko, Hyeong Tak;Suh, Jin Soo
    • Journal of Korean Foot and Ankle Society
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    • v.19 no.1
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    • pp.18-22
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    • 2015
  • Purpose: The purpose of this study is to evaluate the incidence and cause of reamputation with respect to the location of foot amputation. Materials and Methods: Eighty-six patients who received amputations below the ankle level from March 2002 to September 2012 with at least 1 year follow-up were enrolled in this study. We stratified the site of the initial amputation from first to fifth ray and into either the phalanx or metatarsal bone, and investigated the cause of reamputation. Results: The reamputation rate below the ankle level was 53.5%. It was highest (62.1%) in patients with first ray amputations without statistical significance. Rays were divided into two columns, first to third rays as the medial column and others as the lateral column, and reamputation was performed in 61.2% of patients with medial column amputation. Comparing the results between phalanx and metatarsal amputations, reamputation was performed in 62.1% of patients with metatarsal bone amputation. The rate of reamputation was statistically significant in both the medial column and metatarsal amputations. The most common reamputation site, in accordance to the initial site of amputation, was the adjacent ray (57.4%), which was without statistical significance. Moreover, the most common cause of reamputation was osteomyelitis and focal infection in all rays. Conclusion: This study showed that reamputation after amputation below the ankle level was relatively common with highest rate in medial column and metatarsal amputations. Hence, surgeons should be aware of the risk of reamputation and put more preventive effort during medial column and metatarsal amputations.

A Myometric and Electromyographic Analysis of Hip Abductor Musculature in Healthy Right-Handed Persons (고관절 외전시 중둔근의 근력 및 활동전위 변화에 관한 연구)

  • Kwon Hyuk-Cheol
    • The Journal of Korean Physical Therapy
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    • v.2 no.1
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    • pp.35-46
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    • 1990
  • The right hip adbuctor musculature has been reported to demonstrate 'stretch weakness' attributable to chronic elongation imposed by standing posture common to right-handed healthy persons. Kendall and associates have described the concept of 'stretch weakness'. The purpose of this study was to assess isometric hip abduction torque and surface electro-myographic activity (using MYOMED 432) in a sample of 40 healthy right-handed persons (20 male, 20 female), all of whom agreed to participate in the study, and compare side difference in the hip abductor musculature. In order to assure the statistical significance of the results, the paired t-test was applied at the .05 level of significance. The results were as follows : 1. The difference in apparent leg length of right and left legs was significant at the .05 leve1. 2. There was a significant difference between right and left pelvic height (standing position) at the .005 level measurements, and scapula height at the .05 level. 3. Power measurements and action potentials of right hip adbuctor were greater than the left hip adbuctor regardless of the range of joint motion (inner range, outer range). 4. The difference in muscle power and action potentials according to inner or outer range of both hip abductor were significant at the .05 level. 5. In supine during active left hip abduction, the appearance of action potentials in the right hip abductors is indicative of contra-lateral effect (p<.005). These results suggest : In healthy right-handed persons. the apparent leg length on the right is longer than on the left, and pelvic height is elevated on the right side. Muscle torque and muscle action potentials of the right hip adbuctor art higher than those of the hip abductor in the lengthened position. Therefore, the results in this study are contrary to Kendall's. This type of study should be carried out in many physical therapy departments.

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Nurse Wage Structure and Its Determinants in Hospital Industry (전국 병원간호사의 임금구조와 임금수준 결정요인 분석)

  • Kim, Jin Hyun;Ha, Sang Keun;Park, Young Woo;Kim, Yeon Hee;Yi, Sun Mi;Kwon, Hyun Jeong
    • Journal of Korean Clinical Nursing Research
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    • v.25 no.3
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    • pp.294-302
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    • 2019
  • Purpose: The purpose of this study was to investigate the wage structure of hospital nurses in Korea and to analyze the factors that determine the level of nurses' wages. Methods: First, a mobile survey on nurses' wages was conducted with a total of 3,742 nurses working in hospitals. A literature review was also done. Second, a regression model was applied to analyze the determinants of nurses' wages. Results: The average monthly wage of 3,742 nurses based on the survey was KRW 3,588,000 and the standardized monthly income of 3,742 nurses was estimated to be KRW 3,364,000 as of the end of 2018. The results of regression analysis(R2=61.7%) showed that gender, nursing experience, designated night duty, ownership, and number of beds were statistically significant variables for nurses' wages at 1% significance level. The monthly wage of nurses working in total nursing care wards was not significantly different from those working in other wards at 5% significance level. Conclusion: The substantial difference in nurses' wages according to job career, hospital size, region, etc may result in the low proportion of nurses with more than three to five years of service experience and the high turnover of less-experienced workers. Consideration should be given to adjust the gap in wage level and a standard nurse wage system could be effective measures.

Clinico-pathologic Factors and Machine Learning Algorithm for Survival Prediction in Parotid Gland Cancer (귀밑샘 암종에서 생존 예측을 위한 임상병리 인자 분석 및 머신러닝 모델의 구축)

  • Kwak, Seung Min;Kim, Se-Heon;Choi, Eun Chang;Lim, Jae-Yol;Koh, Yoon Woo;Park, Young Min
    • Korean Journal of Head & Neck Oncology
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    • v.38 no.1
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    • pp.17-24
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    • 2022
  • Background/Objectives: This study analyzed the prognostic significance of clinico-pathologic factors including comprehensive nodal factors in parotid gland cancers (PGCs) patients and constructed a survival prediction model for PGCs patients using machine learning techniques. Materials & Methods: A total of 131 PGCs patients were enrolled in the study. Results: There were 19 cases (14.5%) of lymph nodes (LNs) at the lower neck level and 43 cases (32.8%) involved multiple level LNs metastases. There were 2 cases (1.5%) of metastases to the contralateral LNs. Intraparotid LNs metastasis was observed in 6 cases (4.6%) and extranodal extension (ENE) findings were observed in 35 cases (26.7%). Lymphovascular invasion (LVI) and perineural invasion findings were observed in 42 cases (32.1%) and 49 cases (37.4%), respectively. Machine learning prediction models were constructed using clinico-pathologic factors including comprehensive nodal factors and Decision Tree and Stacking model showed the highest accuracy at 74% and 70% for predicting patient's survival. Conclusion: Lower level LNs metastasis and LNR have important prognostic significance for predicting disease recurrence and survival in PGCs patients. These two factors were used as important features for constructing machine learning prediction model. Our machine learning model could predict PGCs patient's survival with a considerable level of accuracy.

Clinical Analysis of Symptoms and Oriental Medical Prescriptions According to Elapsed Time of Stroke in Oriental Medical Hospital Inpatients

  • Yun, Hen-Ja;Sung, Kang-Keyng
    • Herbal Formula Science
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    • v.20 no.1
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    • pp.133-147
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    • 2012
  • Objectives : This study was intended to understand characteristics of symptoms, oriental medicine prescription and laboratory test results according to elapsed time of stroke. Methods : Through the medical records of 205 stroke inpatients in the oriental medical hospital in the year 2010, we investigated manifested symptoms, administered oriental medicine prescription and clinical pathological examination results. Collected items were classified to depend on stroke types, cerebral infarction and hemorrhage. We analyzed association between manifested symptoms, the oriental medicine prescription, and laboratory test results of stroke patients and elapsed time. Chi-square tests were performed to determine the significance level of association. Results : All symptoms, prescriptions and laboratory test results in cerebral infarction patients were associated with elapsed time. Especially, symptoms, prescriptions and pathological examination results showed very high statistical significance with elapsed time (a symptom; chi-square(df)=164.3(22), p<0.001, prescription; chi-square(df)=93.5(22), p<0.001, and pathological examination results; chi-square(df)=164.3(22), p<0.0004). But in the case of cerebral hemorrhage, there was not statistical significance. Conclusions : The elapsed time of stroke may be an essential requisite in catching symptoms and prescribing for stroke patients in oriental medical treatment.

A Study on the Significance of Spatial Interaction Model from the Urban Competitive Point of View (입지 경쟁력과 공간상호작용 모형의 유의성 검정)

  • Kim, Dong-Yoon
    • Journal of The Korean Digital Architecture Interior Association
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    • v.12 no.1
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    • pp.71-79
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    • 2012
  • This study aims at finding relationships between the competitiveness of cities and the size or distance of them, based on some premises; (1) the competitiveness can be measured on the interval-ratio level, that is, factor scores, (2) a hypothesis that the spatial interaction model is valid for the relationships can be generally accepted. Based on the general recognition a research hypothesis that the more is the population or the nearer is the distance from a central city the higher is the competitiveness score is constructed. According to the premises 5-factor scores and composite score are calculated by means of regression method, and the scores are regressed on cities' populations and distances from Seoul city. Using bootstrapping method for the tests of significance is effective due to small sample of 21 cities. Results of the analyses show that most aspects of the hypothesis should be rejected or adjusted. Scores on Health-welfare factor, public service factor, and commercial vitality factor have no relation to the cities' sizes or distances. But the results also find the facts that the strong (negative) relationships exist between (1) educational base factor score and population, (2) density factor score and distance. Although this study improves systematic and analytic understanding of spatial interaction patterns, the understanding should be invalid for the general context because it has used the data on 21 cities in the capital region at the time of 2009.

A Clinical Study on the Effects of Saenggan-tang (생간탕(生肝湯)의 효능(效能)에 관(關)한 임상적(臨床的) 연구(硏究))

  • Lee, Bo-Hyeong;Kim, Deok-Ho;U, Hong-Jeong;Kim, Byeong-Un
    • The Journal of Internal Korean Medicine
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    • v.11 no.1
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    • pp.29-40
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    • 1990
  • In order to study the effect on liver diseases, Saenggan-tang has been applied to 26 patients of chronic hepatitis, 9 patients of liver cirrhosis, 5 patients of acute hepatitis, 8 patients of alcoholic liver diseases, 1 patient of hepatoma total 49 patients visiting the first internal medicine department of the hospital of Oriental Medicine, Kyung Hee University. The Saenggan-tang was taken every 4 weeks (ecept acute hepatitis every 2 weeks). 1. Saenggan-tang had decrease on activity of SGOTF SGPT, with the passage of time, 4, 8, and 12 weeks, showing statistically significant effect. 2. Saenggan-tang revealed sharp decrease on levels of total bilirubin and alkaline phosphatase no showing significance in relation to a few cases 3. Serum protein total and albumin levels were in normal limit before or after Saenggan-tang treatment 4. Triglyceride level was lowered remarkably after Saenggan-tang treatment, showing significance in alcoholic liver disease group whereas no significance in chornic hepatitis Judging from above results, it is proved that Saenggan-tang has curative effect of liver diseases such as acute, chronic hepatitis, liver cirrhosis, alcobolic liver diseases and so on.

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Study on Correlation between the Gait Analysis Indices and Lumbar X-ray Indicators (보행과 기립위 요추 방사선 지표와의 상관성 연구)

  • Park, Jong-Han;Jeong, Su-Hyeon
    • Journal of Korean Medicine Rehabilitation
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    • v.27 no.4
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    • pp.121-130
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    • 2017
  • Objectives This study was designed to investigate the correlation between the gait analysis indices and Lumbar X-ray indicators. Methods 21 cases of patients who received treatment from October 2013 to February 2017 for abnormal posture were analyzed. Three indicators were measured in the lumbar spine X-ray. These indicators include Ferguson's angle, Lumbar lordotic angle, L4-5 IVD angle. Gait analysis indices were estimated by Treadmill Gait Analysis system. The data were analyzed to find out correlation between the gait analysis indices and Lumbar X-ray indicators. Spearman correlation was used. Results Ferguson's angle and Difference of gait balance of front and rear had a negative linear relationship, but there was no statistical significance. Lumbar lordotic angle and Difference of gait balance of front and rear had a negative linear relationship, but there was no statistical significance. L4-5 IVD angle and Difference of gait balance of right and left had a negative linear relationship, but there was no statistical significance. Conclusions Difference of gait balance of front and rear had strong level of a negative linear relationship with Ferguson's angle and Lumbar lordotic angle.

hMSH2 and nm23 Expression in Sporadic Colorectal Cancer and its Clinical Significance

  • Wu, Hong-Wei;Gao, Li-Dong;Wei, Guang-Hui
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.3
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    • pp.1995-1998
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    • 2013
  • Objective: To study the expression of the mismatch repair proteins hMSH2 and nm23 in sporadic colorectal cancer, determine any inter-relationship, and further investigate any clinical significance. Methods: Expression of hMSH2 and nm23 proteins was assessed in 87 colorectal cancer tissues by SP immunohistochemistry, with analysis of survival using follow-up data. Results: In the sporadic colorectal cancer tissues, nm23 protein expression appeared independent of the histological type (P>0.05), but correlated with the invasion depth and lymphatic metastasis (P<0.05). In contrast, hMSH2 protein expression was not significantly correlated with these clinicopathologic features (P>0.05), although it positively correlated with that of nm23 protein in the sporadic colorectal cancers (rs=0.635, P<0.05). Combined expression of the two was found to be related with invasion depth, lymphatic metastasis and prognosis of sporadic colorectal cancer (P<0.05). Conclusion: nm23 protein level was related with the degree of malignancy, and could be used as an index to predict the invasion and metastasis potential. The expression of hMSH2 protein is positively correlated that of nm23 protein, and the combined expression of the two has certain guiding significance for the prognosis of sporadic colorectal cancer.

The Study on the Concentrations of Lead and Cadmium in of the Inhabitants of Jeon-Ju Indurstrial Area (전주공업단지 주변 주민들의 모발내 Pb 및 Cd함량에 관한 연구)

  • 이종섭;유일수;이기남
    • Journal of Environmental Health Sciences
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    • v.14 no.2
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    • pp.89-96
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    • 1988
  • This study was carried out to evaluate the concentrations of heavy metal in hair of the inhabitants of Jeon-Ju industrial area. The major findings of this study are as follows 1. The average content of lead in hair of the inhabitants of Jeon-Ju industrial area was 15.06$\pm$ 4.06 ppm and the content of lead of driver's hair showed higher than that of house wives and students, and showed significance statistically ( P < 0.05). 2. The average content of cadmium by occupation in hair of inhabitants of Jeon-Ju industrial area was 0.76$\pm$ 0.21 ~ 0.52$\pm$ 0.16 ppm and the cadmium concentration in hair of driver's showed the highest level among occupations and showed significance statistically (P < 0.05). 3. Lead and cadmium contents in the hair of the inhabitants of Jeon-Ju industrial area showed higher than that of control area residents and showed significance statistically ( P < 0.05 ). 4. The contents between lead and codmium in hair of Jeon-Ju industrial area residents revealed high degree of correlation ( r = 0.7938).

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