• Title/Summary/Keyword: Short-term safety

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Characteristics of Chloride Penetration with Deicer Types (제설제 종류에 따른 염화물 침투 특성)

  • Choi, Yoon-Suk;Kim, Kang-Rea;Kim, Myung-Yu;Yang, Eun-Ik
    • Proceedings of the Korea Concrete Institute Conference
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    • 2006.11a
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    • pp.549-552
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    • 2006
  • Deicing salt has been generally used for prevention of a road freezing in winter, and the amount is increasing every year. However, deicing salt may induce the decrease of bond strength, surface scaling, and environmental pollution, etc. The purpose of this paper is to suggest the fundamental data on safety and durability for concrete structures through the estimation of characteristics of chloride penetration with deicer types. According to the test results, as age of concrete is increased, chloride penetration depth is also increased independent of deicer types. However, there is no remarkable difference between deicer types. And when the estimation of chloride diffusion is carried out by immersion test, diffusion coefficient is decreased with ages, and short-term estimation may overestimate the coefficient.

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Management of Benign Esophageal Strictures in Children

  • Vandenplas, Yvan
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.20 no.4
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    • pp.211-215
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    • 2017
  • Esophageal strictures are seldom in children. In many countries, accidental ingestion of corrosives is a major cause of risk for stricture formation. Therefore, their management is a challenge. Safety and long-term efficacy of esophageal dilation for benign esophageal strictures has been confirmed in children. Because most children with structures are toddlers or younger, balloon dilatation is often preferred over bouginage. There is increasing evidence that short duration administration of high doses steroids may be of benefit in some specific situation (IIb esophagitis according to Zargar classification). Mytomycin-C application needs to be further evaluated. Stenting was reported to be successful in some refractory cases.

Crack growth prediction on a concrete structure using deep ConvLSTM

  • Man-Sung Kang;Yun-Kyu An
    • Smart Structures and Systems
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    • v.33 no.4
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    • pp.301-311
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    • 2024
  • This paper proposes a deep convolutional long short-term memory (ConvLSTM)-based crack growth prediction technique for predictive maintenance of structures. Since cracks are one of the critical damage types in a structure, their regular inspection has been mandatory for structural safety and serviceability. To effectively establish the structural maintenance plan using the inspection results, crack propagation or growth prediction is essential. However, conventional crack prediction techniques based on mathematical models are not typically suitable for tracking complex nonlinear crack propagation mechanism on civil structures under harsh environmental conditions. To address the technical issue, a field data-driven crack growth prediction technique using ConvLSTM is newly proposed in this study. The proposed technique consists of the four steps: (1) time-series crack image acquisition, (2) target image stabilization, (3) deep learning-based crack detection and quantification and (4) crack growth prediction. The performance of the proposed technique is experimentally validated using a concrete mock-up specimen by applying step-wise bending loads to generate crack growth. The validation test results reveal the prediction accuracy of 94% on average compared with the ground truth obtained by field measurement.

Radiological Safety Assessment of a HLW Repository in Korea using MASCOT-K (MASCOT-K를 이용한 가상 방사성폐기물 처분장에서의 종합성능 평가)

  • 황용수;이연명;강철형
    • Tunnel and Underground Space
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    • v.10 no.4
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    • pp.553-558
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    • 2000
  • Since 1977, KAERI has conducted the fundamental R&D on the permanent disposal of potential HLW repository in Korea. The first ten year project is divided into three short-term phase studies. The first phase study which shall be finished in March of 2000, has the prime target to develop the disposal concept of HLW. Throughout this study the preliminary and generic disposal repository system has been introduced. The potential repository is proposed to be emplaced into crystalline rocks which is the most common rock types in Korea. The proposed depth of the repository is between 300 to 700 meter. The numerical code, MASCOT-K was developed to asserts the long term safety of the proposed repository concept. Based on this conceptual design preliminary safely assessment was performed. Results show that for the given disposal system the potential radioactive release it well below the regulatory limit.

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Need-based development of tailored nutritional education materials about food additives in processed foods for elementary-school students (초등학생을 위한 가공식품 속 식품첨가물 영양교육 요구도 조사 및 맞춤형 영양교육 자료 개발)

  • Kim, Ki Nam;Lee, A Reum;Lee, Hae Ryun;Kim, Kirang;Hwang, Ji-Yun
    • Journal of Nutrition and Health
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    • v.46 no.4
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    • pp.357-368
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    • 2013
  • Tailored nutritional education is generally found to be more effective in changing behaviors and to be more fully implemented than a non-tailored equivalent. This study was conducted in order to develop tailored nutritional education materials on food additives in processed foods based on need and levels of knowledge of educational targets of elementary-school students in Seoul Metropolitan City. The focus group interview was conducted with six elementary-school nutrition teachers in order to gather information and to develop a tailored quantitative questionnaire for the survey. Based on the results from 138 nutrition teachers, all answered that education on food additives in processed foods for students is necessary and both teachers and students need to receive education regarding definition, safety, and use of food additives for each processed food, in the form of video, PPT, and teaching-learning plan. Nutritional education materials for two classes were developed using video clips (grocery shopping and cooking class) about food additives in processed foods, PPTs with activity papers, two teaching-learning plans, and school newsletters to parents. In conclusion, the current study warrants conduct of further studies short-term and long-term impacts and efficacy of tailored need-based nutrition education in promotion of healthy nutrition by conveying proper scientific knowledge regarding food additives in processed foods for elementary-school students.

Mutagenicity studies of food and cosmetic dyes (1) (식용 및 외용색소의 유전독성에 관한 연구 (1))

  • 하광원;정해관;오혜영;허옥순;손수정;한의식;정성철;한순영;최선주
    • Journal of Food Hygiene and Safety
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    • v.8 no.3
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    • pp.171-179
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    • 1993
  • The mutagenicity of 22 food and cosmetic dyes had been evaluated. Two different short-term mutagenicity tests were used: (1) Salmonella typhimurium preincubation assay (Ames test) (2) Chromosome aberration test with cultured Chinese hamster lung (CHL) fibroblast cells. Orange No. 203 was mutagenic in Salmonella typhimurium with and without rat liver microsomal activation, and Red No. 204 was mutagenic in Salmonelhl typhimurium with rat liver microsomal activation. Red No. 104-1 and Red No. 215 showed slight increase of chromosomal aberration in CHL cells.

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Feasibility and Safety of Totally Laparoscopic Radical Gastrectomy for Advanced Gastric Cancer: Comparison with Early Gastric Cancer

  • Lee, Seungyeob;Lee, Hayemin;Lee, Junhyun
    • Journal of Gastric Cancer
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    • v.18 no.2
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    • pp.152-160
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    • 2018
  • Purpose: Totally laparoscopic gastrectomy (TLG) for advanced gastric cancer (AGC) is a technically and oncologically challenging procedure for surgeons. This study aimed to compare the oncologic feasibility and technical safety of TLG for AGC versus early gastric cancer (EGC). Materials and Methods: Between 2011 and 2016, 535 patients (EGC, 375; AGC, 160) underwent curative TLG for gastric cancer. Clinicopathologic characteristics and surgical outcomes of both patient groups were analyzed and compared. Results: Patients with AGC required a longer operation time and experienced more intraoperative blood loss than those with EGC did. However, patients from both the AGC and EGC groups demonstrated similar short-term surgical outcomes such as postoperative morbidity (14.4% vs. 13.3%, P=0.626), mortality (0% vs. 0.5%, P=0.879), time-to-first oral intake (2.7 days for both groups, P=0.830), and postoperative hospital stay (10.2 days vs. 10.1 days, P=0.886). D2 lymph node dissection could be achieved in the AGC group (95%), with an adequate number of lymph nodes being dissected ($36.0{\pm}14.9$). In the AGC group, the 3-year overall and disease-free survival rates were 80.5% and 73.7%, respectively. Conclusions: TLG is as safe and effective for AGC as it is for EGC.

A Study on Institutionalization of the Rent-A-Driver Industry from the Point of View at the Creative Industries

  • OH, Moon-Kap;YOUN, Myoung-Kil
    • Korean Journal of Artificial Intelligence
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    • v.7 no.2
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    • pp.1-8
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    • 2019
  • This paper, we argue that sector in terms of the creative industries the need to the institutional settle of the rent-a-driver business; the industry could create more than 200,000 jobs, the effect is to bring out the about 4 trillion underground economy and Can be interpreted industry, which contributes to reduce social costs, ranging from 1.7 trillion won to 5.7 trillion per year. Through institutionalization of policy should support. Observation and in-depth interviews were conducted with the law and the president of the rent-a-driver business company. The operating system should be improved. the rent-a-driver business, for the formulation of the work ethic and education is desperately needed. The effect socio-economic contribution effect of the rent-a-driver business industry can be summarized as follows. First, it is an industry that has an operating system utilizing state-of-the-art technology and equipment, and the convergence of creative industries to comply with the market. Second, the effect appears as an industry that creates jobs for the populace to replace the social security system, social safety net is considered as an industry. Third, this is an industry that can be self-reliant in the short term at least political support, the industry is considered in the industry to maximize the effectiveness and efficiency of the support policy.

Safety and outcomes of subconjunctival allogenic mesenchymal stem cell transplantation in canine experimental corneal defects

  • Kim, Ju-Won;Lee, So-Young;Park, Hee-Myung
    • Korean Journal of Veterinary Research
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    • v.52 no.3
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    • pp.157-162
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    • 2012
  • Corneal injury is very common clinical condition in veterinary medicine and delayed or incomplete corneal healing has the potential of vision loss due to the loss of corneal transparency. For the reconstruction of corneal epithelium, tissue graft and cell transplantation have been prosperously investigated. The purpose of this study was to evaluate the clinical value and short-term safety of application of cultured allogenic mesenchymal stem cells (MSCs) in the treatment of canine experimental corneal defect. Corneal defects were surgically generated in the central corneas of healthy beagle dogs and cultured canine allogenic MSCs were transplanted via subconjunctival injection. Although mean healing time, the rate of epithelial regeneration, and the degree of corneal transparency were not significantly improved after MSC transplantation, significant immune reaction or incompatibility reaction was not detected except transient local irritation. These results propose the possibility of MSC application as a new regenerative medicine in canine ocular disorders.

Characteristics of Prostaglandin Synthesis Induced by Bacterial Lipopolysaccharide in Rat Alveolar Macrophages (Bacterial Lipopolysaccharide가 Prostaglandin 합성에 미치는 작용의 특성)

  • 이수환;임종석;황동호;문창규
    • Journal of Food Hygiene and Safety
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    • v.8 no.4
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    • pp.181-188
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    • 1993
  • It is well known that bacterial lipopolysaccharide (LPS) stimulates the prostaglandin (PG) synthesis in various experimental system, but the mechanism and the detailed nature of its action are yet to be understood. Thus, this study was designed to characterize LPS induced PG synthesis in rat alveolar macrophage. Although results were not so much prominent, LPS stimulated PGE2 synthesis in macrophage with short term exposure, and this was thought to be mainly due to the activation of phopholipase A2+ But there was a burst in the PG synthesis 6 hours after the LPS treatment and this was accompanied with the increase of cyclooxygenase activity. This effect was not mediated by tumor necrosis factor (TNF) or platelet activating factor (PAF), and the existence of serum was prerequisite for its action. Growth factors such as epidermal growth factor (EGF) and platelet derived growth factor (PDGF) themselves did not stimulate PG synthesis and the showed stimulatory activities to some extent. Normal rat serum was more effective for the elicitation of the LPS action than growth factors. Thus, considering the amounts of growth fafctors contained in normal serum, it was suggested that another factors like LPS binding protein (LBP) might be involved in the serum effect on LPS action. Conclusively. it was thought that LPS could stimulate PG synthesis through interaction with serum factors such as EGF, PDGF and/or LBP.

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