• Journal of the Korean Institute of Landscape Architecture
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• v.38 no.3
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• pp.1-14
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• 2010

Areas with negative images in cities can degrade the image of the city as a whole and slow the city's efforts to improve its image. The identification of such areas and the development of a city contour that charts the images of various areas in advance can help urban planners establish relevant strategies to ameliorate detrimental images of the city. This study intends to draw a contour of Seongnam City according to citizen's cognition levels of and preference for city area images and aim to shift the strategy of urban image planning from being results-oriented to being process-oriented. The results of this study are as follows: First, an analysis of the level of cognition of and preferences for Seongnam City's landmarks shows that the degree of cognition varies in different areas, whereas that of preferences remains similar; Second, the cognition and preference contour makes it easy to assess and diagnose city images; Third, the image management map, which merges the cognition contour with the preference contour, divides the city into four different areas. In order to manage city images, it follows that those areas with a high degree of cognition but low preference need to be classified and dealt with first. Further, this study shows that those areas with high cognition are the most populated and visited. Areas with high preference can become a strong candidate for being a landscape control point of a city, which adds to the usefulness of this study. The contour of Seongnam will contribute to networking sightseeing areas for visitors centered upon those places of high preference. It would appear that this type of networking will inspire a better image for the city.

• Genomics & Informatics
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• v.12 no.4
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• pp.240-246
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• 2014

Mutation in HNF1B, the hepatocyte nuclear factor-$1{\beta}$ (HNF-$1{\beta}$) gene, results in maturity-onset diabetes of the young (MODY) 5, which is characterized by gradual impairment of insulin secretion. However, the functional role of HNF-$1{\beta}$ in insulin secretion and glucose metabolism is not fully understood. We identified a family with early-onset diabetes that fulfilled the criteria of MODY. Sanger sequencing revealed that a heterozygous P159L (CCT to CTT in codon 159 in the DNA-binding domain) mutation in HNF1B was segregated according to the affected status. To investigate the functional consequences of this HNF1B mutation, we generated a P159L HNF1B construct. The wild-type and mutant HNF1B constructs were transfected into COS-7 cells in the presence of the promoter sequence of human glucose transporter type 2 (GLUT2). The luciferase reporter assay revealed that P159L HNF1B had decreased transcriptional activity compared to wild-type (p < 0.05). Electrophoretic mobility shift assay showed reduced DNA binding activity of P159L HNF1B. In the MIN6 pancreatic ${\beta}$-cell line, overexpression of the P159L mutant was significantly associated with decreased mRNA levels of GLUT2 compared to wild-type (p < 0.05). However, INS expression was not different between the wild-type and mutant HNF1B constructs. These findings suggests that the impaired insulin secretion in this family with the P159L HNF1B mutation may be related to altered GLUT2 expression in ${\beta}$-cells rather than decreased insulin gene expression. In conclusion, we have identified a Korean family with an HNF1B mutation and characterized its effect on the pathogenesis of diabetes.

• Journal of the Korean Chemical Society
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• v.64 no.5
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• pp.304-317
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• 2020

This study was conducted on four 11^th grade students at a high school in a small town to determine the effectiveness of responsive teaching. The three phases of the responsive teaching method proposed in the previous study were subdivided into six stages; Step 1 is elicitation of students' thoughts related to macroscopic world, Step 2 is drawing of students' early thoughts related to microscopic world, Step 3 is disciplinary connections with ideas of the particle, Step 4 is to clarify the learner's thoughts on the particle by the teacher's involvement, Step 5 is deepening students' thoughts, and Step 6 is expanding ideas. In Step 4, students came to the recognition that the cause of mass was atoms and that the cause of volume was molecules. In Step 5, students led to a shift in thinking that could ignore the volume of the molecules themselves through the properties of protons and neutrons that affect mass from a particle perspective. In the Step 6 of expanding ideas, students explained molecular motion by the concept of material point which ignores the volume of particles. This steps gave students perspectives on the relationship between the mass and volume of particles required by Avogadro's law. The students recognized that some systems could be studied only indirectly because they were too small, too large, too fast, or too slow to observe directly.

• Korean Security Journal
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• no.61
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• pp.9-38
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• 2019

As the scales & density of the Korean national infrastructures have been increased, they will be identified as rich and attractive potential targets for intensified North Korea's attack in the rear region and terrorism attack. In addition, due to changes in security environment such as drone threats and lack of security forces under the 52-hour workweek law, I think that it is the proper time point to reevaluate the effectiveness and appropriateness of the current physical protection system and its shift to a new system. In this study, the direction and improvement of the perimeter physical protection systems of the national infrastructures are to be studied from the viewpoints of its concepts of operations and design methodology, focusing on the nuclear power plant. The reason why we focus on nuclear power plants is because they cause wide-range and long-term damages caused by radioactive materials disperal and pollution, along with short-term damage caused by the interruption of electricity generation in the event of damage to nuclear power plants. With the aim of extracting improvement directions, as we will comprehensively review domestic research trends and domestic·overseas related laws, and consider Korea's specificity, we try to reframe the concept of operation - systematization, mobilization and flexibility -, and establish criteria on system change. In order to improve the technical performance of the new perimeter physical protection system, we study on high-fidelity·multi-methodology based integrated design methodology, breaking from individual silo-type design methods, and I suggest improvement of government procurement, its expansion to export business and other national infrastructure.

• Journal of Korean Philosophical Society
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• v.130
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• pp.109-134
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• 2014

In (Advaita) $Ved{\bar{a}}nta$ although human beings are destined to have a pessimistic starting point in life, their goal of life is to become a Perfect Being which is called 'Liberation' (mokṣa) by self-transcendence. This human goal together with several means are accepted by $Ved{\bar{a}}nta$ as solely valuable thing in the life. In this way there must be a self-recognition of his own value in the process of Liberation, through which one recognizes his own true nature i.e. ${\bar{A}}tman$. ${\bar{A}}tman$ is clearly defined to be 'Existence, Consciousness, Bliss' (Being, Illumination, Good), and this definition is made with the view of revealing that It is ultimate foundation and source of human beings ontologically, epistemologically and axiologically. However, as $Ved{\bar{a}}ntic$points of view on human goal are not without critical limitations, it may be necessary to revaluate 'the process of self-inquiry' devised to achieve human goal. Inquiry is, first of all, an accepting process of what is given in $Ved{\bar{a}}nta$ as the scenario that gives rise to most actual result, then, a performing and verifying process of that scenario in one's own experience consistently. In this process, a shift of action from worldly life to unworldly life is what is called 'self-adjustment', a removal of 'the self in excess' through knowledge of the real Self is what is called 'simplification of the self', and at the end of simplification a state of ultimate Self is 'Liberation'. Therefore, the inquiry of $Ved{\bar{a}}nta$ into human goal can be summarized as following formula; 'good action = self-adjustment' ${\rightarrow}$ 'good knowledge = simplification of the self' ${\rightarrow}$ 'Liberation = ultimate Self'.

• Journal of Technology Innovation
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• v.29 no.4
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• pp.1-30
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• 2021

Due to the recent development of system semiconductors, technical innovation for the electric devices of the automobile industry is rapidly progressing. In particular, the electric device of automobiles is accelerating technology development competition among automobile parts makers, and the development cycle is also changing rapidly. Due to these changes, the importance of strategic planning for R&D is further strengthened. Due to the paradigm shift in the automobile industry, the Product-Technical Roadmap (P/TRM), one of the R&D strategies, analyzes technology forecasting, technology level evaluation, and technology acquisition method (Make/Collaborate/Buy) at the planning stage. The product-technical roadmap is a tool that identifies customer needs of products and technologies, selects technologies and sets development directions. However, most companies are developing the product-technical roadmap through a qualitative method that mainly relies on the technical papers, patent analysis, and expert Delphi method. In this study, empirical research was conducted through simulations that can supplement and strengthen the product-technical roadmap centered on the automobile industry by fusing Gartner's hype cycle, cumulative moving average-based data preprocessing, and deep learning (LSTM) time series analysis techniques. The empirical study presented in this paper can be used not only in the automobile industry but also in other manufacturing fields in general. In addition, from the corporate point of view, it is considered that it will become a foundation for moving forward as a leading company by providing products to the market in a timely manner through a more accurate product-technical roadmap, breaking away from the roadmap preparation method that has relied on qualitative methods.

• Journal of Korean Neurosurgical Society
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• v.62 no.6
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• pp.643-648
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• 2019

Objective : Shunt-dependent hydrocephalus (SdHCP) is a well-known complication of aneurysmal subarachnoid hemorrhage (SAH). The risk factors for SdHCP have been widely investigated, but few risk scoring systems have been established to predict SdHCP. This study was performed to investigate the risk factors for SdHCP and devise a risk scoring system for use before aneurysm obliteration. Methods : We reviewed the data of 301 consecutive patients who underwent aneurysm obliteration following SAH from September 2007 to December 2016. The exclusion criteria for this study were previous aneurysm obliteration, previous major cerebral infarction, the presence of a cavum septum pellucidum, a midline shift of >10 mm on initial computed tomography (CT), and in-hospital mortality. We finally recruited 254 patients and analyzed the following data according to the presence or absence of SdHCP : age, sex, history of hypertension and diabetes mellitus, Hunt-Hess grade, Fisher grade, aneurysm size and location, type of treatment, bicaudate index on initial CT, intraventricular hemorrhage, cerebrospinal fluid drainage, vasospasm, and modified Rankin scale score at discharge. Results : In the multivariate analysis, acute HCP (bicaudate index of ${\geq}0.2$) (odds ratio [OR], 6.749; 95% confidence interval [CI], 2.843-16.021; p=0.000), Fisher grade of 4 (OR, 4.108; 95% CI, 1.044-16.169; p=0.043), and an age of ${\geq}50years$ (OR, 3.938; 95% CI, 1.375-11.275; p=0.011) were significantly associated with the occurrence of SdHCP. The risk scoring system using above parameters of acute HCP, Fisher grade, and age (AFA score) assigned 1 point to each (total score of 0-3 points). SdHCP occurred in 4.3% of patients with a score of 0, 8.5% with a score of 1, 25.5% with a score of 2, and 61.7% with a score of 3 (p=0.000). In the receiver operating characteristic curve analysis, the area under the curve (AUC) for the risk scoring system was 0.820 (p=0.080; 95% CI, 0.750-0.890). In the internal validation of the risk scoring system, the score reliably predicted SdHCP (AUC, 0.895; p=0.000; 95% CI, 0.847-0.943). Conclusion : Our results suggest that the herein-described AFA score is a useful tool for predicting SdHCP before aneurysm obliteration. Prospective validation is needed.

• The Korean Journal of Archival Studies
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• no.37
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• pp.3-39
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• 2013

The purpose of this study is to analyze the present stage of community archives movement in the UK. By doing so, it draws some implications of the UK case for the community archives movement in Korea. The UK's 'Independent' community archives as a part of grassroots movement are characterized by participation, autonomy, and self-help of community members. Along with the appearance of the concept of 'community', the UK has experienced the revitalization period of community archives in the social context of community-based urban regeneration project. Recently, the UK's community archives have transformed themselves into building a 'governance model' relying on the partnership with mainstream archives. In particular, the UK model of community archives is based 'on their own ways' with their autonomy as a product of intrinsic development initiated by communities themselves. The character of the model of this type is very analogous to the nature of maul' community archives movement in Korea. Since the early 2000s, however, the UK model of community archives has been evolving into a way of building governance through their appropriation of the skills and methodologies from mainstream archives without endangering the autonomous essences of community archives themselves. We need to note the point of local researchers' view in archival science who have tried to seek out the methodology for building maul community archives with regard to openness and collaboration. In this respect, a shift in archival principle in the UK would give significant implications in regenerating the locally based community model.

• Applied Chemistry for Engineering
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• v.30 no.3
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• pp.297-302
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• 2019

In order to investigate structural changes of the pyrolysis fuel oil (PFO), the volatile matters and heavy oil fractions were separated from PFO by heat treatment temperature. As a result of $^1H-NMR$ analysis of volatile matters, 1~2 ring aromatic compounds contained in the petroleum residue were mostly removed at a temperature before $340^{\circ}C$. Moreover, new peaks corresponding to aliphatic hydrocarbons were detected at the chemical shift of 2.0~2.4 ppm. It is attributed that the aliphatic hydrocarbon sidechain was cracked from the aromatic compound by the cracking reaction occurred at $320^{\circ}C$. The C/H mole ratio and aromaticity increased with increasing the heat treatment temperature. Therefore, from the structural analysis results of heavy oil fractions and volatile matters from PFO, the decomposition of the aliphatic sidechain by cracking reaction and the separation of volatile matters by boiling point of components were mostly affected structure changes of the PFO.

• Journal of Christian Education in Korea
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• v.64
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• pp.81-107
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• 2020

Church education in Korean churches is facing a very serious crisis. This crisis is a negative perception of the church as viewed by the present society. The negative perception of the church has led to children, adolescents, young adults, and even adults leaving the church. There have been countless studies on the problem of Christian education and its alternatives. However, those problems still remain a matter of church education. The alternatives do not become viable and remain a problem. To solve these problems, a paradigm shift is required, and in order to overcome the crisis of the church, it is necessary to study alternatives and its method factors and find application points. Today's church education is absolutely influenced by postmodernism and informationalization. However, church education is education for Christian identity that transmits Christian faith. This Christian education is facing challenges and crises against its religious and academic identity. Christian education has a responsibility to be aware of this reality and to present alternatives to overcome various crises facing church education. Therefore, it is the task of church education to establish standards so that we can live a life where the Bible becomes the standard. In other words, it is to give them biblical faith. Furthermore, it is necessary to point out and understand Christian faith in the Korean church, which has been evaluated as insufficient. In addition, establishing a Christian worldview and realizing the Kingdom of God that practice justice and love in society are tasks that can be accomplished efficiently through Christian education. Therefore, the Korean church should actively seek ways to support the practice of Christian education as well as church education in forming ideal Christians which is the goal of Christian education.