• Journal of Oral Medicine and Pain
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• v.43 no.1
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• pp.21-25
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• 2018

Syphilis, one of the most common sexually transmitted diseases, is caused by the microorganism Treponema pallidum. Syphilis consists of several clinical stages that may include signs in the oral and perioral regions. Syphilis is treated effectively with systemic antimicrobial therapy using antibiotics such as penicillin. This article describes a case where topical antibacterial therapy with doxycycline was effective in treating oral papular lesions associated with primary syphilis in a 24-year-old male. He was immediately referred to a dermatologist, and antibiotic therapy was administered in response to positive diagnostic test results for syphilis. Although oral syphilitic lesions may be resolved by dental professionals using topical treatments, syphilitic infections should be managed in consultation with medical specialists using systemic antibiotic therapy.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.12 no.3
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• pp.374-381
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• 2005

Purpose: The purpose of this study was to identify the level of sexual knowledge of male high school students. Method: The Participants were 503 male students from a high school in one county of Gangwon Province. The data were collected from May 1 to May 30, 2004. Collected data were analyzed using SPSS program to investigate the responses to the structured questionnaires used in the study. Results: The level of sexual knowledge of high school students was 10.25(range 0 to 17). In terms of response distribution of sexual knowledge by items, the correct response rate was highest for 'wet dream is discharge of semen during sleep', and the wrong response rate was lowest in 'gonorrhea occurred most frequency in 15-25 year old adolescents'. General characteristics showed significant differences in sexual knowledge depending on grade(grade 3 :10.45, grade 2: 10.40, grade1: 9.88). Depend on the sexual impulse and the solutions to sex problems, there were significant differences in sexual knowledge with respect to sexual characteristics. Conclusion: As a whole the sexual knowledge of the male high school students was low, sexual education programs for high school students should focus on sexually transmitted diseases and contraception.

• Parasites, Hosts and Diseases
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• v.58 no.2
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• pp.135-145
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• 2020

Infections caused by Trichomonas vaginalis in humans are one of the main public health problems caused by sexually transmitted diseases. Objective of this study was to evaluate potential biological activity of the medicinal plant Argemone mexicana (Mexican poppy) on T. vaginalis. Methanolic extracts of the stems and leaves of A. mexicana, and different fractions were prepared with solvents of different polarities. The extracts and functional groups were detected containing sterols, triterpenes, quinones, flavonoids and, alkaloids. Extracts from both the stems and leaves of A. mexicana inhibited the growth of T. vaginalis with half-maximal inhibitory concentration value of 70.6 and 67.2 ㎍/ml, respectively. In the active fractions, the most abundant compounds were berberine and jatrorrhizine, with presumed antiparasitic activity.

• Clinical and Experimental Reproductive Medicine
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• v.47 no.4
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• pp.245-262
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• 2020

In recent years, nanotechnology has revolutionized global healthcare and has been predicted to exert a remarkable effect on clinical medicine. In this context, the clinical use of nanomaterials for cancer diagnosis, fertility preservation, and the management of infertility and other pathologies linked to pubertal development, menopause, sexually transmitted infections, and HIV (human immunodeficiency virus) has substantial promise to fill the existing lacunae in reproductive healthcare. Of late, a number of clinical trials involving the use of nanoparticles for the early detection of reproductive tract infections and cancers, targeted drug delivery, and cellular therapeutics have been conducted. However, most of these trials of nanoengineering are still at a nascent stage, and better synergy between pharmaceutics, chemistry, and cutting-edge molecular sciences is needed for effective translation of these interventions from bench to bedside. To bridge the gap between translational outcome and product development, strategic partnerships with the insight and ability to anticipate challenges, as well as an indepth understanding of the molecular pathways involved, are highly essential. Such amalgamations would overcome the regulatory gauntlet and technical hurdles, thereby facilitating the effective clinical translation of these nano-based tools and technologies. The present review comprehensively focuses on emerging applications of nanotechnology, which holds enormous promise for improved therapeutics and early diagnosis of various human reproductive tract diseases and conditions.

• Journal of Korean Academy of Nursing
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• v.27 no.2
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• pp.423-432
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• 1997

This is a descriptive study to understand the preventive stage for STDs to provide a basis for sex education for college students. The colleges were selected by quota sampling in five representative cities in Korea. but the 1,691 college students were selected by convenient sampling in the cities nationwide, and the data were collected by self-reporting using a questionnaire consisting of 33 items. The results were as follows : 1. Their mean ages were 21.8 for female and 23.3 for male students, 2.78.0% of the males md 46.5% of the females permitted premarital sex, 57.1% of male and 10.3% of female college students had experienced sexual intercourse, 7. l% of males and 2.4% of females had experienced pregnancy, 10.3% of males and 3.4% of females had been infected with STDs, 72.1% of male and 13.8% of female didn't use condoms at the time of infection. 3. Most of the factors related to STDs infection, such as drinking, smoking, frequency of sexual intercourse. pregnancy, knowledge of STDs, the score of STDs prevention were statistically higher in the male student group than in the female group. 4. The students' mean score of knowledge about STDs was similar between the male group(7.80) and the female group(7.84) with a possible score range from 0-18. 5. Only fifteen percent of male and 9.6% of female students expressed that they will do something to prevent STD. 6. The group having the experience of sexual intercourse(t=3.924, P=.048) and the group of having experience of contracting STDs(t=16.638, P=.000) had shown statistically higher STDs prevention score than the group not having that kind of experience. but the group having experience with pregnancy didn't show any difference from. the group not having experience with pregnancy. Considering that 57.1% of males and 10.3% of females had sexual intercourse experience, 78% of male and 46.5% of female permitted premarital sex, 10.3% of male and 3.4% of female had been infected with STDs. It could be concluded that the college students were ignorant about the prevention of STDs and had unrealistic stage of the STDs prevention. Therefore, enforcement of education for the prevention of STDs including the dynamics of the sexual intercourse and STDs infection is needed.

• Parasites, Hosts and Diseases
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• v.52 no.5
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• pp.551-555
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• 2014

Trichomonas vaginalis, a causative agent of trichomoniasis, may trigger symptomatic or asymptomatic non-gonococcal urethritis and chronic prostatitis in men. Despite the availability of highly sensitive diagnostic tests, such as nucleic acid amplification tests, including PCR, few prospective studies present data on male T. vaginalis infection in South Korea. In the present study, the prevalence of T. vaginalis and associated clinical conditions were evaluated in 201 male patients from a primary care urology clinic in South Korea. The prevalence of T. vaginalis infection in our cohort was 4% (8/201) by PCR. T. vaginalis infection was common in men older than 40 years (median age, 52 years). Among the 8 Trichomonas-positive patients, 87.5% (7/8) had prostatic diseases, such as prostatitis and benign prostatic hyperplasia, and 25.0% (2/8) and 12.5% (1/8) were coinfected with Chlamydia trachomatis and Mycoplasma genitalium, respectively. Our results suggest that T. vaginalis infection is not rare in men attending primary care urology clinics in South Korea, especially in those older than 40 years, in whom it may explain the presence of prostatic disease. The possibility of T. vaginalis infection should be routinely considered in older male patients with prostatic diseases in South Korea.

• The Journal of Korean Society for School & Community Health Education
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• v.8 no.1
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• pp.1-11
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• 2007

Objectives: School must provide the proper sex education to students, thereby, the students for have right standards of sexuality and preventing from sexual crimes. This study conducted to identify the effectiveness and students' satisfaction level on Sex education program for middle school students prepared by the Ministry of Education and Human Resources. Methods: The sample size of the study was 644 students(458 female students and 186 male students) in middle school. A self reporting type of questionnaire survey was conducted from May 2 through May 27, 2005. Collected data were processed using SPSSwin 12.0; The data were analysed through t-test, stepwise multiple regression analysis. Results: Lectures and audiovisual materials were mostly used for sex education for students. Many students were satisfied with the program of physical and sexual organ development, pregnancy, contraceptive methods and sexual abuse. Many students wanted to study more on courtship, love, and marriage. The programs which the students did not understand well were sexually transmitted diseases, pregnancy and mass media and sex. Forty six percentage of the students reported that they were satisfied with the education program. Thirty three percentage of the students said that they were not satisfied with the program. The students who had earlier menstruation experience and the students whose academic achievement were higher were more satisfied with sex education program (P<.05). The students who were satisfied with the sex education CD prepared by the ministry of education were more satisfied with sex education program. (P<.001). When the CDs were appropriately used, the students were more satisfied with the education program (P<.05). The sound and pictures in the CD did not much affect the students. Audiovisual programs were more effective than lectures.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.19
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• pp.8287-8293
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• 2014

Background: This study assessed human papillomavirus (HPV), cervical cancer, and HPV vaccine knowledge and awareness among women in two sub-populations in Nepal - Khokana, a traditional Newari village in the Lalitpur District about eight kilometers south of Kathmandu, and Sanphebagar, a village development committee within Achham District in rural Far-Western Nepal. Methods: Study participants were recruited during health camps conducted by Nepal Fertility Care Center, a Nepali non-governmental organization. Experienced staff administered a Nepali language survey instrument that included questions on socio-demographics, reproductive health and knowledge on HPV, cervical cancer, and the HPV vaccine. Results: Of the 749 participants, 387 (51.7%) were from Khokana and 362 (48.3%) were from Sanphebagar. Overall, 53.3% (n=372) of women were aware of cervical cancer with a significant difference between Khokana and Sanphebagar (63.3% vs 43.0%; p=0.001). Overall, 15.4% (n=107) of women had heard of HPV and 32% (n=34) of these women reported having heard of the HPV vaccine. If freely available, 77.5% of the women reported willingness to have their children vaccinated against HPV. Factors associated with cervical cancer awareness included knowledge of HPV (Khokana: Odds Ratio (OR)=24.5; (95% Confidence Interval (CI): 3.1-190.2, Sanphebagar: OR=14.8; 95% CI: 3.7-58.4)) and sexually transmitted infections (Khokana: OR=6.18; 95% CI: 3.1-12.4; Sanphebagar: OR=17.0; 95% CI: 7.3-39.7) among other risk factors. Conclusions: Knowledge and awareness of HPV, cervical cancer, and the HPV vaccine remains low among women in Khokana and Sanphebagar. Acceptance of a freely available HPV vaccine for children was high, indicating potentially high uptake rates in these communities.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.3
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• pp.1497-1500
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• 2014

Cervical cancer continues to be an important public health problem in Thailand. While the high risk human papillomavirus (HPV) types have been established as the principle causative agent of both malignancies and the precursor lesions, cervical intraepithelial neoplasia (CIN), other factors may also be involved like other sexually transmitted diseases, as well as smoking. Chlamydia trachomatis is an obligate intracellular Gramnegative bacterium which has a tendency to cause chronic infection featuring inflammation and therefore might be expected to increase the risk of cervical cancer. In the present nested case-control study, 61 cases of cervical cancer and 288 matched controls with original serum samples were identified from the Khon Kaen Cohort, established in the North-East of Thailand, by linkage to the Khon Kaen population based cancer registry. C. trachomatis specific IgG antibodies at recruitment were measured by microimmunofluorescence and assessed for association with cervical cancer using STATA release10. No significant link was noted either with all cancers or after removal of adenocarcinomas. The results suggest no association between Chlamydia infection and cervical cancer development in North-East Thailand, but possible influencing factors must be considered in any future research on this topic.

• Journal of Microbiology and Biotechnology
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• v.18 no.2
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• pp.350-354
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• 2008

In order to investigate the prevalence of sexually transmitted viruses such as human papillomavirus (HPV) and herpes simplex virus (HSV) in Korean commercial sex workers (CSWs), we selected 188 CSWs (age range 20-44 years, median age 24 years) who regularly visited one public health center in Seoul, Korea. HPV genotypes were analyzed by using a HPV DNA Chip, and an enzyme-linked immunosorbent assay (ELISA) was used to detect type-specific IgG against HSV2 antibody identifying seropositivity for HSV2 infection. Polymerase chain reaction (PCR) was performed with specific primers to detect HPV and HSV1/2 in cervical swabs from the CSWs. The prevalence of HPV infection was 83.5% in 188 cervical swab specimens and the main high-risk HPV genotypes were HPV16, 18, 56, and 58. The principal low-risk HPV genotypes were HPV6 and 11. The prevalence of HSV1/2 DNA was 13.8% and HSV2 seroprevalence was 86.2%. These results suggest that high frequencies of HPV and HSV2 infection might contribute to the rapid spread of STD viruses in CSWs in Korea. Additionally, an understanding of why high-risk HPV genotypes are so prevalent could provide guidelines for prophylactic vaccine development in Korea.