• 제목/요약/키워드: Sexes

검색결과 1,244건 처리시간 0.03초

Troglitazone Lowers Serum Triglycerides with Sexual Dimorphism in C57BL/6J Mice

  • Jeong Sun-Hyo;Yoon Mi-Chung
    • Biomedical Science Letters
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    • 제12권2호
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    • pp.65-72
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    • 2006
  • Thiazolidinediones (TZDs) are widely used antidiabetic drugs that activate the nuclear peroxisome proliferator-activated receptor ${\gamma}(PPAR{\gamma})$, and thereby improve the metabolic abnormalities linking hypertriglyceridemia to diabetes, hyperglycemia, insulin resistance, and cardiovascular disease. To determine whether the $PPAR{\gamma}$ ligand troglitazone regulates lipid metabolism with sexual dimorphism, we examined the effects of troglitazone on circulating lipids, body weight and the expression of hepatic genes responsible for lipid metabolism in both sexes of C57BL/6J mice. Compared to mice fed a low fat control diet, both sexes of mice fed a troglitazone-treated low fat diet for 14 weeks did not exhibit changes in body weight gain, serum total cholesterol, HDL-cholesterol and LDL-cholesterol levels. However, serum triglycerides were significantly reduced in both sexes of mice, although these effects were more pronounced among males. Furthermore, troglitazone regulated the expression of hepatic genes critical for lipid and lipoprotein metabolism, the magnitudes of which were much higher in males compared to females, as evidenced by results for increased acyl-CoA oxidase and decreased apolipoprotein C-III mRMA levels. These results suggest that $PPAR{\gamma}$ activator troglitazone may exert sexually dimorphic control of serum triglycerides in part through the differential activation of $PPAR{\gamma}$ in liver between male and female mice.

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The association of blood pressure with body mass index and waist circumference in normal weight and overweight adolescents

  • Song, Young-Hwan
    • Clinical and Experimental Pediatrics
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    • 제57권2호
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    • pp.79-84
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    • 2014
  • Purpose: Overweight can be defined by the body mass index (BMI) and is likely associated with an increased cardiovascular disease risk. However, waist circumference (WC), a central adiposity index, may be a better indicator of cardiovascular disease risk. Studies comparing the effects of BMI and WC on cardiovascular risk factors, such as high blood pressure (BP), are rare in adolescents. Methods: We analyzed the correlations of BMI and WC with BP in 3,363 Korean adolescents (aged 10-19 years), using data from the Korean National Health and Nutrition Examination Surveys (2009-2011). Results: Systolic BP (SBP) in both sexes and diastolic BP (DBP) in boys were higher in the high BMI (>85th percentile) and high WC (>90th percentile) groups. High BMI and high WC were positively correlated with high SBP (>90th percentile) in both sexes, and high DBP (>90th percentile), in boys. BMI maintained its positive associations with SBP, DBP, high SBP, and high DBP in the normal weight ($BMI{\leq}85th$ percentile) and overweight (BMI>85th percentile) groups in both boys and girls, as well as in all subjects of both sexes, even after adjustment for WC. However, WC did not correlate with SBP, DBP, high SBP, or high DBP after adjustment for BMI in any group in either sex. Conclusion: In Korean adolescents, BMI correlated better with BP and high BP levels than WC. Further, BMI was positively associated with BP and high BP in the normal weight group as well as in the overweight group.

A New Species of the Genus Bryocamptus (Copepoda, Harpacticoida, Canthocamptidae) from Alpine Wetlands at Jeju Island, Korea

  • Lee, Jimin;Chang, Cheon Young
    • Animal Systematics, Evolution and Diversity
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    • 제32권3호
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    • pp.219-229
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    • 2016
  • Material of a Bryocamptus species, formerly reported as B. umiatensis Wilson, 1958 from Sakhalin and South Korea, is here recognized as a distinct new species. Specimens of both sexes were recently obtained from an alpine wetland, Sumeunmulbaengdui, located in the Hallasan National Park, Korea, and newly registered as a Ramsar Wetland in 2015. The new species, B. jejuensis n. sp., differs from the type population of B. umiatensis from Alaska by the smooth margin of the anal operculum in both sexes, the peculiarly modified terminal seta on the distal endopodal segment of the male leg 3, the sword-like spinous seta on the distal endopodal segment of the male leg 4, and the presence of a setule row on the inner distal margin of the caudal rami in the female. Both sexes of the new species are described in detail with particular reference to the male characters. A revised key to the seven species of the genus Bryocamptus Chappuis, 1929 occurring in Korean waters is provided.

An Investigation on Acute Drug Intoxication of Inhabitants in Sim-An Islands Area (일부낙도지역주민의 음독에 의한 급성약물중독발생에 대한 조사)

  • Choi, Sam-Sop;Lee, Woo-Hyuk
    • Journal of agricultural medicine and community health
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    • 제9권1호
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    • pp.109-116
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    • 1984
  • The epidemiological information on 156 cases of acute drug intoxication treated at emergency room of Sin An Dai-Woo Hospital in Bi-Gum island during the year of 1981-1982 were reviewed and analyzed. And the findings obtained was as follows : 1) Annual incidence rate of acute drug intoxication was 3.3 per 1,000 in habitants (male 3.5, female 3.1). 2) In both sexes the highest incidence was obsesved in the age group of 20~49 years with 7.6 in male and 6.2 in female per 1,000 inhabitants. 3) In both sexes the highest ease distribution was observed during summer season of July and August (male 33.2%, female 26.4%). 4) Eating pesticides was the most frequently used for suicide purpose in both sexes (male 89. 3%, female 82.2%). 5) In terms of foundation for conclusion to eating poison, "by guardion's explanation" was the highest rate in both groups of eating pesticides (97.8%) and eating rodentcides(77.8%). 6) The case fatality rate due to eating poison was 4.5% (male 5.9%, female 2.8%). 7) In haspitalization days, the most cases was observed at less than 3 days (male 73.8%, female 79.2%).

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THE STUDY OF THE ERUPTION PATTERN OF THE MAXILLARY FIRST PERMANENT MOLAR (상악(上顎) 제1대구치(第一大臼齒)의 맹출과정(萌出過程)에 관(關)한 연구(硏究))

  • Kim, Hyun-Kyu
    • Journal of the korean academy of Pediatric Dentistry
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    • 제11권1호
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    • pp.13-24
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    • 1984
  • To Study the eruption pattern of the maxillary first permanent molar, the author took 266 cases of true lateral cephalogram (Male; 137 cases, Female; 129 cases) from 3 to 7 years old children and observed the vertical change and axial change. The following results were obtained: 1. The angle of axial inclination of the maxillary first permanent molar to the F-H plane increased gradually from age 3 to 7, except for age 6 in both sexes. There was a slight reversal of this motion at age 6. 2. The distance from the cusp of the maxillary first permanent molar to the occlusal plane slightly decreased from age 3 to 5, and rapidly decreased from age 5 in both sexes. 3. The change of angle of the axial inclination resulted in the distance from the distobuccal cusp of the maxillary first permanent molar to the occlusal plane decreasing more than that from the mesiobuccal cusp of the maxillary first permanent molar to the occlusal plane in both sexes. 4. The eruption of the maxillary first permanent molar generally was found to be earlier in girls than boys.

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STATISTICAL STUDY ON DENTAL CARIES INCIDENCES OF INLAND SCHOOL CHILDREN IN CHOONG CHUNG BUK DO OF KOREA (한국 내륙지방 충주.중원지역 학동의 치아우식발생빈도에 관한 통계학적 연구)

  • Chung, Tae-Hyoung;Lee, Jong-Gap
    • Journal of the korean academy of Pediatric Dentistry
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    • 제11권1호
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    • pp.181-189
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    • 1984
  • 1,840 school children aged 6 to 13 years who live in inland area in CHOONG CHUNG BUK DO were surveyed epidemiologically on the dental caries prevalence. The results were as follows; 1. The prevalence of dental carries was 76.35 percentage in male, 76.15 percentage in female, and 76.25 percentage in both sexes. 2. d.m.f rate was 77.72 percentage in male, 80.07 percentage in female, and 78.86 percentage in both sexes. D.M.F rate was 30.73 percentage in male, 38.52 percentage in female, and 34.51 percentage in both sexes. 3. d.m.f.t. rate and index was 27.94 percentage,2.55T, and d.m.f.s. rate & index was 13.62 percentage, 6.22T. 4. D.M.F.T rate & index in permanent teeth was 4.86 percentage,0.72T, and D.M.F.S. rate & index was 1.20 percentage,0.89T. 5. The filling rate was 3.90 percentage in decidious teeth, 2,00 percentage in permanent teeth.

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A ROENTGENOGRAPHIC STUDY OF CORTICAL THICKNESS AND BONE DENSITY OF MANDIBLE (하악골의 피질골두께와 골치빈도에 관한 방사선학적 연구)

  • Shin Dong Jin;Lee Sang Rae
    • Journal of Korean Academy of Oral and Maxillofacial Radiology
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    • 제14권1호
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    • pp.51-59
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    • 1984
  • The aim of this study was to investigate the thickness of angular cortex and bone density of mandible in normal person. Age changes and sex differences of those were comprised in this study. Material included 456 pantomographic views and 309 intraoral films taken by paralleling technic. 1. Conclusions from this study were as follows. The thickness of mandibular angular cortex increased with age in both sexes before 15 to 19-year-old group. And those were relatively constant in the age range from 20 to 49 years in male and in the age range from 20 to 39 years in female, but decreased after that age. 2. The thickness of mandibular angular cortex were larger in male than in female. And no significant differences between sexes were noted before 40 to 49-year-old group. 3. Changes of bone density with age were analogous to changes of thickness of mandibular angular cortex. Correlation coefficients between changes of bone density and age were arranged, and male group underwent comparatively low correlation while insignificant statistically in female gruop. And no significant differences between sexes were found in all age groups except 50 to 59-year-old group.

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A STUDY ON THE CHARACTERISTICS OF CRANIOFACIAL SKELETON IN ANTERIOR OPEN-BITE (전치부(前齒部) 개방교합자(開放咬合者)의 악안면(顎顔面) 골격(骨格) 특성(特性)에 관(關)한 연구(硏究))

  • Kim, Mee-Kyung;Cha, Kyung-Suk
    • The korean journal of orthodontics
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    • 제21권3호
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    • pp.501-511
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    • 1991
  • This study was performed to verify the craniofacial skeletal characteristics in anterior openbite group, in contrast to normal occlusion group, and also to find out, vertical factors which shows, correlate to the amount of anterior openbite. 21 individuals, including 10 males and 11 females, without orthodontic treatment history and anterior - posterior skeletal malrelationships, were selected and analyzed basic morphology and vertical factors, using standard lateral cephalogram. The obtained results as follows: 1. Comparison of anterior open-bite group with normal occlusion group using Moyers analysis. a) In basis morphologic analysis, Ba-SE-Me was lesser and Ba-SE-Mn. P. and Mn.P/A-B were greater in both sexes of anterior openbite group than in normal occlusion group. b) In angle measurements of vertical analysis, PMV/Pal. P. was lesser in male anterior openbite group and PMV/Occ. P. and PMV/Mn. P. were greater in both sexes of anterior openbite group than in normal occlusion group. c) In height ratio of vertical analysis, ATFH/PTFH and ALFH/ATFH were greater in both sexes of anterior openbite group than in normal occlusion group. 2. The amount of anterior openbite was correlated with PMV/Occ. P. and PMV/Mn. P.

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A Study on Mate Selection and Sexual Consciousness(I) -Investigation for Unmarried Japanese Women College Students- (배우자선택과 성의식에 관한 연구(I) -일본 여자대학생을 대상으로-)

  • 김혜선;김영희
    • Journal of Families and Better Life
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    • 제1권2호
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    • pp.107-125
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    • 1983
  • This study aimed to clarify the attitude toward marriage, mate selection and sexual consciousness of japanese unmarried women students whom are believed in drastic change in a overall social value system and norm due to the introduction of western civilization, so as to provide some information of the same subject of our young women in similar situation. Survey was carried out for 177 unmarried Japanese women students of 3 Universities located in Osaka prefecture situation. Data were collected by means of Questionnaire and analyzed by SPSS BATCH SYSTEM. Result are as follows; 1) Pattern of mate selection- An increasing tendency of love match is recognized 2) Attitude to marriage-94.0% of correspondences want to marry and proper age of marriage, they think, is between 22-25 years. 3) Love-marriage relation- most correspondences answered that love is a prior condition for marriage, however, 32.8% of correspondences think, love can be built after the marriage. 4) Dating- most correspondences want free dating, however, they fell that they are lacking for opportunity and they are not confident in the selection of proper mate. 5) Premarital sexual intercourse-most correspondences show a very generous attitude toward premarital sexual intercourse if they are in love and this attitude becomes more remarkable among love match makers. 6) Equality of sexes-most correspondences answered that as women are different in physiological function from men, distinctive social roles of both sexes and the inequality of sexes are inevitable.

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Minh Mang Thang, the Mysterious Vietnamese Prescription Containing Korean Ginseng

  • Thi Hong Van Le;Van Dan Nguyen;Manh Hung Tran
    • Journal of Ginseng Culture
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    • 제6권
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    • pp.1-12
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    • 2024
  • Emperor Minh Mang (明命), the second ruler of the Nguyen Dynasty in Vietnam, reigned from 1820 to 1841. He is widely regarded by contemporary historians as the most distinguished monarch of his dynasty, despite some controversial policies. One aspect of his extraordinary legacy is the remarkable 142 offspring he sired - 78 princes and 64 princesses - earning him the unprecedented distinction of having the most progeny among kings in world history. Vietnamese people suppose Minh Mang's prolific reproductive success to the consumption of a specially prescribed medicine known as Minh Mang Thang (明命湯, MMT). This medicine, often associated with sexual potency and fertility, is characterized by intriguing names such as "One night Five sexes," "One night Six sexes born Five babies," or "Six sexes Three pregnancies." Vietnamese folklore vividly recounts Minh Mang's exceptional sexual prowess, attributing it to the use of MMT. MMT formulations, which include various herbs, notably Korean ginseng, may incorporate additional botanical ingredients depending on their intended purpose. This paper aims to explore the origins, history, ingredients, and applications of MMT, unraveling the mystery behind this mystical prescription that has inspired several oriental medicinal researchers. Through this investigation, we seek to shed light on the cultural and historical contexts surrounding Minh Mang's use of MMT and its enduring impact on traditional Vietnamese medicine and folklore.