• Archives of Reconstructive Microsurgery
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• v.11 no.2
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• pp.179-185
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• 2002

The wrist and forearm are a frequently damaged area in high tension electrical injury as an input or output of the current. Electrical burns affecting the wrist and forearm may produce full thickness necrosis of the skin and damage deep vital structures beneath the eschar, affecting the local tendons, nerves, even bones and joints which result in serious dysfunction of the hand. From January 1997 to December 2001, we had treated 20 patients with high tension electrical burn in the wrist and forearm using anterolateral thigh free flap. Average follow up period were 24 months and we get satisfactory results both in functional and aesthetic aspects. This flap is considered useful in one-stage reconstruction of wide and large soft tissue defect combined with arterial injuries.

• Archives of Reconstructive Microsurgery
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• v.17 no.1
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• pp.7-13
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• 2008

Popliteal artery injury in blunt trauma of knee joint is not common but poses high rate of amputation due to anatomical characteristics or delayed diagnosis and treatment. The aim of the present study is to review the authors' experiences with this condition and identify factors contributing to disability. We reviewed 7 cases of popliteal artery injury in trauma around knee. Injury mechanism, type of vessel damage, associated injuries, mangled extremity severity scores (MESS), ischemic time and additional treatments were analyzed. Tibial fracture, distal femoral fracture and serious soft tissue defect were combined. Mean MESS was 9.9 point and mean time of revascularization was 7.1 hours. Transfemoral amputation was performed in 2 cases due to vascular insufficiency and devastating infection, and 4 patients were able to walk without any support at the last follow up. Age, the severity of soft tissue injury, ischemic time and MESS are thought to be related to prognosis, and young patients with short ischemic time show best results, but authors experienced one exceptional case. We have to consider multiple factors related to the prognosis in popliteal artery injury with fractures around knee, and careful decision is needed regarding to early amputation.

• Korean Journal of Clinical Pharmacy
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• v.29 no.4
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• pp.223-230
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• 2019

Background: Small-molecule tyrosine kinase inhibitors (TKIs) have had major impacts on anticancer therapy by targeting the catalytic activities of dysregulated tyrosine kinases. TKIs have not presented traditional toxicities; however, some serious adverse effects, including hepatotoxicity, have been documented in clinical trials and post-marketing surveillance. Although TKI-induced hepatotoxicity can cause severe clinical complications in patients, the underlying mechanism is still unclear. Methods: Studies on TKI-induced hepatotoxicity were identified by Pubmed search, and relevant articles were reviewed. Results: Immunoallergic reaction, cytochrome P (CYP) 450 polymorphisms, and formation of reactive metabolites are under consideration as mechanisms of TKI-induced hepatotoxicity. Host protein-drug metabolite conjugates are recognized as antigens by class II major histocompatibility complexes and are believed to cause liver injuries. Polymorphisms in CYP, which influences TKI metabolism, can slow TKI metabolism and may induce development of hepatotoxicity. The formation of reactive metabolites during drug metabolism can induce hepatotoxicity by directly causing cytotoxicity, leading to cell dysfunction, and indirect toxicity by mediating secondary immune reactions. Concurrent use of various medications with TKI can also cause hepatotoxicity by affecting drug transporter or enzyme activities. Conclusion: Periodic monitoring of patients taking TKIs and risk/benefit reassessments though post marketing surveillance are necessary to prevent hepatotoxicity.

• Journal of The Korean Society of Clinical Toxicology
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• v.2 no.1
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• pp.58-62
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• 2004

Acid ingestion can cause not only caustic injury on esophagus and stomach but also fatal outcome through systemic complications. We report the case of a patient who died early after severe caustic injury with strong acid. A 38-year-old man who ingested about 400ml of hydrochloric acid of unknown concentration was transferred to our hospital from a private clinic, in which he was managed with gastric irrigation through a nasogastric tube. He was complaining dyspnea and abdominal pain. Physical examination demonstrated tenderness and rebound tenderness on epigastric region. Severe metabolic acidosis and leukocytosis were noted. Radiological findings suggested perforation of gastrointestinal tract, although the physical signs were not typical. Endoscopy revealed caustic injuries of grade I on esophagus and of grade Ⅲ on stomach, which indicate more severe injury on the stomach than on the esophagus. Exploratory surgery was recommended but unfortunately not permitted by his family. Despite intensive measures, his vital signs deteriorated rapidly and he died 50 hours after the ingestion.

• Journal of The Korean Society of Clinical Toxicology
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• v.2 no.1
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• pp.63-66
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• 2004

Hydrofluoric acid (HF), one of the strongest inorganic acids, is used mainly for industrial purpose. Hydrofluoric acid injuries has a potential for both systemic as well as severe local tissue destruction. One of the most serious consequences of severe exposure to HF by any route is marked lowering of serum calcium (hypocalcemia) and other metabolic changes, such as hypomagnesemia and which may result in a fatal outcome if not recognized and treated. promptly cardiotoxicity is not well known except arrhythmias, which are a primary cause of death. We report a case of myopericarditis by ingestion of hydrofluoric acid.

• Journal of the Korean Society of Safety
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• v.20 no.3 s.71
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• pp.164-173
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• 2005

In this paper, the systematic problems of safety management in domestic construction industry are presented by the investigation and analysis of construction fatal injuries. In particular, it is discussed that the current construction safety management system by contractors leading is ineffective to prevent the serious accidents caused by inappropriate planning and design and to circulate the safety management cycle without interruption. A couple of ways for improving domestic construction safety management system are suggested in broad perspective. This is done by the analysis of construction safety management system of four advanced industrial countries such as the United States, the United Kingdom, Germany, and Japan and the study of a best practice. Total safety management system by owners leading is recommended to prevent construction accident effectively because this system makes all the parties join to the management system and distribute the responsibilities clearly to each party. This will drop the accident occurrence rate by dragging all the parties' cooperations and activating the total safety management system in an early stage.

• Journal of the Korean Society of Safety
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• v.37 no.4
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• pp.1-10
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• 2022

The purposes of this study were to suggest 1) a future direction for Korea's machine tool industry and 2) how to secure the safety and reliability of emerging intelligent or automated machine tooling. The study concludes that, overseas, the machine tool industry is growing again while promoting innovation by converging with ICT. Accordingly, Korea also promotes ICT innovation to advance the machine tool industry, which is at the core of the national economy. As a result, unlike in the past, the frequency of serious injuries like entrapment accidents has recently decreased, while the proportion of collision accidents has increased. In addition, a new type of accident has become possible. Since ICT is network-based, the distinction between work and rest can become ambiguous; there is a risk of hacking, working hours and places are flexible and there are risk factors for diseases like chronic fatigue due to overload of specific personnel. As robots and automation are introduced, there is also a high probability of problems caused by physical and psychological burdens on system operators and resulting fatigue.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.26 no.8
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• pp.1165-1171
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• 2022

Human behavior recognition using an accelerometer has been applied to various fields. As smartphones have become used commonly, a method for human behavior recognition using the acceleration sensor built into the smartphone is being studied. In the case of the elderly, falling often leads to serious injuries, and falls are one of the major causes of accidents at construction fields. In this article, we proposed recognition method for human falling direction using built-in acceleration sensor and orientation sensor in the smartphone. In the past, it was a common method to use the magnitude of the acceleration vector to recognize human behavior. These days, deep learning has been actively studied and applied to various areas. In this article, we propose a method for recognizing the direction of human falling by applying the deep learning multilayer technique, which has been widely used recently.

• International Journal of Internet, Broadcasting and Communication
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• v.15 no.1
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• pp.85-96
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• 2023

The number of traffic accidents caused by wet or icy road surface conditions is on the rise every year. Car crashes in such bad road conditions can increase fatalities and serious injuries. Historical data (from the year 2016 to the year 2020) on weather-related traffic accidents show that the fatality rates are fairly high in Korea. This requires accurate prediction and identification of hazardous road conditions. In this study, a forecasting model is developed to predict the chances of traffic accidents that can occur on roads affected by weather and road surface conditions. Multiple deep learning algorithms taking into account AlexNet and 2D-CNN are employed. Data on orthophoto images, automatic weather systems, automated synoptic observing systems, and road surfaces are used for training and testing purposes. The orthophotos images are pre-processed before using them as input data for the modeling process. The procedure involves image segmentation techniques as well as the Z-Curve index. Results indicate that there is an acceptable performance of prediction such as 65% for dry, 46% for moist, and 33% for wet road conditions. The overall accuracy of the model is 53%. The findings of the study may contribute to developing comprehensive measures for enhancing road safety.

• Journal of the Korean Burn Society
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• v.24 no.2
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• pp.30-33
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• 2021

Purpose: Dalgona, a kind of candy made of caramelized sugar, is a popular snack for children. Given the popularity of preparing dalgona, increasingly many patients are treated for burns sustained while preparing dalgona. We report the clinical features and dangers of burns from dalgona. Methods: We retrospectively reviewed the clinical records of 11 inpatients and outpatients who had been treated for burns they received while preparing dalgona from March 2020 to December 2020. The data reviewed were age, sex, the severity of the burn, the size and location of the burn, the type of treatment, and the place where the injury occurred. Results: The age of the patients ranged from 3 to 19 years, and the average age was 10.2 years (2 male, 9 female). Three patients had superficial second-degree burns, while eight had deep second-degree or third-degree burns. Most of the cases were treated with a local skin flap or skin graft. All the burned lesions were on the hands and feet. In all cases, the burns occurred at home due to accidental spillage. Conclusion: Most of the patients were children and teenagers, and they had serious burns. Therefore, we report these findings to emphasize the need for public awareness of the potential for burn injuries to occur during dalgona preparation.