• KSBB Journal
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• v.28 no.6
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• pp.339-348
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• 2013

Translational research (TR) as high quality research can accelerate collaboration strongly between biotechnology-based researchers and clinical-research experts for overcoming diseases. TR facilitates basic science translated to clinical efficacy and effectiveness from bench (basic science) to bedside (clinical practice) for the enhancement of human health. Disease-oriented TR programs were defined as unilateral, bilateral and multilateral TR in this patent performance analysis. Patent performance was measured in a R&D project on Health and Medical Technology to enhance the productivity of R&D investment on disease-oriented TR in Health Technology (HT). Patent Map (PM) analysis and Bibliometrics were conducted to collect information for the assessment of research patents of TR programs. Futhermore, PIAS (Patent Information Analysis System) and Thinklear programs were applied for quantitative and qualitative analysis successfully. These indicate that multi-dimensional analysis of patent performance for disease-oriented TR could promote the connection of R&D-IP (Research and Development-Intellectural Property) and R&BD (Research and Business Development) supporting system significantly.

• Journal of The Korean Association For Science Education
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• v.35 no.3
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• pp.343-352
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• 2015

This study is to discover the diverse issues related to Self-Directed Learning Screening (SDLS) and draw implications by analyzing its critical points. Using content analysis and interviews with admission officers, tentative issues were finalized and reviewed by researchers and educators. A Survey was developed based on the 96 issues after having evidence of content validity using the Delphi method. To conduct survey, e-mails were sent to admissions officers in twenty science specialized high schools. They were asked to response to questions about perceptions of critical issues and if there are any issues in their schools. Using mean scores of two factors based on its critical issues and frequencies, a two-dimensional classification table for each type was presented. Four critical issues for each type were discovered. The first type indicates minor issues that include 28 items that were less than the overall mean scores in terms of critical issues and its frequencies. The second type indicates tentative issues that include 29 items that were greater than the mean score in critical issues but less in its frequencies. The third type indicates general issues that include 17 items that were less than the mean score in critical issues but greater in its frequencies. The last type indicates critical issues that include 22 items that were greater than the mean scores in two factors. The discovered results of critical issues and its types in this study can be considered a core part of the screening process in schools, especially, critical issues should play an important role in the process of admission screening planning.

• Progress in Medical Physics
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• v.20 no.3
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• pp.174-179
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• 2009

To track moving tumor in real time, CyberKnife system imports a technique of the synchrony respiratory tracking system. The fiducial marker which are detectable in X-ray images were demand in CyberKnife Robotic radiosurgery system. It issued as reference markers to locate and track tumor location during patient alignment and treatment delivery. Fiducial marker implantation is an invasive surgical operation that carries a relatively high risk of pneumothorax. Most recently, it was developed a direct lung tumor registration method that does not require the use of fiducials. The purpose of this study is to measure the accuracy of target applying X-sight lung tracking using the Gafchromic film in dynamic moving thorax phantom. The X-sight Lung Tracking quality assurance motion phantom simulates simple respiratory motion of a lung tumor and provides Gafchromic dosimetry film-based test capability at locations inside the phantom corresponding to a typical lung tumor. The total average error for the X-sight Lung Tracking System with a moving target was $0.85{\pm}0.22$ mm. The results were considered reliable and applicable for lung tumor treatment in CyberKnife radiosurgery system. Clinically, breathing patterns of patients may vary during radiation therapy. Therefore, additional studies with a set real patient data are necessary to evaluate the target accuracy for the X-sight Lung Tracking system.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.43 no.3 s.345
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• pp.49-58
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• 2006

In this paper, a curve-fitting channel estimation method is proposed for orthogonal frequency division multiplexing (OFDM) system in a time-varying frequency-selective fading channel. The method can greatly improve channel state information (CSI) estimation accuracy by performing smoothing and interpolation through consecutive curve-fitting processes in both time domain and frequency domain. It first evaluates least-squares (LS) estimates using pilot symbols and then the estimates are approximated to a polynomial with proper degree in the LS error sense, starting from one preferred domain in which pilots we densely distributed. Smoothing, interpolation, and prediction are performed subsequently to obtain CSI estimates for data transmission. The channel estimation processes are completed by smoothing and interpolating CSI estimates in the other domain once again using the channel estimates obtained in one domain. The performance of proposed method is influenced heavily on the time variation and frequency selectivity of channel and pilot arrangement. Hence, a proper degree of polynomial and an optimum approximation interval according to various system and channel conditions are required for curve-fitting. From extensive simulation results in various channel environments, we see that the proposed method performs better than the conventional methods including the optimal Wiener filtering method, in terms of the mean square error (MSE) and bit error rate (BER).

• Journal of Soil and Groundwater Environment
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• v.12 no.6
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• pp.29-37
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• 2007

Shallow alluvial groundwaters in Korea of tell exceed the Korean Drinking Water Standard for dissolved iron (0.3 mg/L), which is one of the important water quality problems, especially in the use of bank infiltration technique. Using the reactive transport modeling, in this study we simulated the effectiveness of injection-and-pumping technique to remove dissolved iron in groundwater. The results of simulation showed that pumping of groundwater after injection of oxygenated water into aquifers is very effective to acquire the permissible water quality level. Groundwater withdrawal up to several times of irjected water in volume can be applicable to yield drinkable water. Potential problems such as clogging and permeability lowering due to in-situ precipitation of iron hydroxides may be insignificant. We also discuss on the mechanism and spatial extent of iron removal in aquifer.

• Journal of the Korean Wood Science and Technology
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• v.35 no.4
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• pp.14-20
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• 2007

The properties of the wood pellets from damaged wood by forest fire and sound woods were investigated. Oven-dry densities of pellets made from sound wood and the damaged wood of Pinus densiflora were 0.93~0.94 and 0.86~0.88, respectively. Compressive strength of the pellets from the woods was ranged from 145 to $168kgf/cm^2$, and there was little difference between the sound wood and the damaged wood of P. densiflora. Ash content for the sound wood and the damaged wood of Pinus densiflora were 0.32~0.37% and 0.25~0.35%, respectively, and calorific values of each pellet were ranged from 18 to 19 MJ/kg. The result of elemental analysis in carbon. hydrogen and oxygen showed 45.8~48.8%, 6.2~6.5% and 46.5~48.0%, respectively. Consequently, there seem no significant difference in the properties between damaged and sound wood pellets.

• Journal of Korean Association for Spatial Structures
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• v.10 no.2
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• pp.105-115
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• 2010

Recently, High-rise building are irregular-shaped to be city landmarks and function as vertical cities to enable the efficient use of land. 3T (Twisted, Tilted & Tapered) designs are being suggested for irregular buildings and studies to develop new structural system have been actively made to satisfy slender shape ratio. In diagrid system, not only gravity load but also lateral load is delivered based on the triangular shape of diagrid, so most of columns are eliminated. Because shearing force is delivered by the axial behavior (tensile/compressive) of diagrid to minimize shearing deformation, the system is more applicable to irregular buildings than existing system where shearing force is delivered by the columns. In this study, the process of selecting connection details and the structural safety of the selected details are verified using the finite element analysis with focus given to the construction overview of the Cyclone Tower. However, the relersed methods of stress concentration are suggested and the performance of stress concentration relieves that it's suggested for the appropriate cap plate thickness and extended length.

• Journal of the Microelectronics and Packaging Society
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• v.13 no.3 s.40
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• pp.9-12
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• 2006

We have designed and fabricated micro power generators by electroplating which is important in MEMS(micro electro mechanical system) technique. We have electroplated MEMS coils on the glass substrates and have chosen one of these coils for experiments. The thickness, width, and length of the coil are $7{\mu}m,\;20{\mu}m$, and 1.6 m, respectively. We have analyzed the structure of MEMS coil by SEM. We have made a vibrating system for reproducible results in measurement. With reciprocating a magnet on the surface of a fabricated winding coil, the micro power generator produce an alternating voltage. We have changed the vibrational frequency from 0.5 Hz to 8 Hz. The generated voltage was 106 mV at 3 Hz and 198 mV at 6 Hz. We aim at the micro power generator which can change vibration energy to useful electric energy.

• Journal of Periodontal and Implant Science
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• v.48 no.5
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• pp.305-316
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• 2018

Purpose: The aim of the present study was to evaluate the biocompatibility and barrier function of mussel adhesive protein (MAP)-loaded collagen membranes in guided bone regeneration (GBR). Methods: Eight male New Zealand white rabbits were used. Four circular defects (diameter: 8 mm) were created in the calvarium of each animal. The defects were randomly assigned to 1) a negative control group, 2) a cyanoacrylate (CA)-loaded collagen membrane group (the CA group), 3) a MAP-loaded collagen membrane group (the MAP group), and 4) a group that received a polycaprolactone block with MAP-loaded collagen membrane (the MAP-PCL group). Specimens were harvested at 2 weeks (n=4) and 8 weeks (n=4) postoperatively for observational histology and histometric analysis. Results: In the histologic analysis, MAP was completely absorbed without any byproducts. In contrast, some of the CA adhesive remained, showing an inflammatory reaction, at 8 weeks. In the MAP-PCL group, the MAP-loaded collagen membranes served as a barrier membrane despite their fast degradation in GBR. No significant difference was found in the amount of new bone between the MAP-PCL and MAP groups ($1.82{\pm}0.86mm^2$ and $2.60{\pm}0.65mm^2$, respectively). Conclusions: The MAP-loaded collagen membrane functioned efficiently in this rabbit calvarial GBR model, with excellent biocompatibility. Further research is needed to assess clinical applications in defect types that are more challenging for GBR than those used in the current model.

• Journal of Advanced Marine Engineering and Technology
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• v.39 no.9
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• pp.881-889
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• 2015

Ocean thermal energy conversion is an organic Rankine cycle that generates power using the temperature difference between surface water and deep water. This study analyzes the thermodynamic efficiency of the cycle, which strongly depends on the working fluid and the cycle configuration. Cycles studied included the classical simple Rankine cycle, Rankine cycles with an open feedwater heater and an integrated regenerator, as well as the Kalina cycle. Nine kinds of simple refrigerants and three kinds of mixed refrigerants were investigated as the working fluids in this study. Pinch-point analysis that set a constant pinch-point temperature difference was applied in the performance analysis of the cycle. Results showed that thermodynamic efficiency was best when RE245fa2 was used as the working fluid with the simple Rankine cycle, the Rankine cycles with an open feedwater heater and an integrated regenerator, and when the mixing ratio of $NH_3/H_2O$ was 0.9:0.1 in the Kalina cycle. If the Rankine cycles with an open feedwater heater, an integrated regenerator, and the Kalina cycle were used for ocean thermal energy conversion, efficiency increases could be expected to be approximately 2.0%, 1.0%, and 10.0%, respectively, compared to the simple Rankine cycle.