• Applied Microscopy
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• v.47 no.4
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• pp.233-237
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• 2017

Chronic eosinophilic leukemia (CEL) is a myeloproliferative disease with an increased number of mature eosinophils and their precursors, which results in infiltration into organs and organ enlargement. The main cause of this disease is the overexpression of tyrosine kinase. However, there is a need for alternative medication, because some patients are resistant to imatinib, which is a tyrosine kinase inhibitor for leukemia. Many studies have indicated that S100A8 and splicing factor proline and glutamine-rich (SFPQ) function as initiation signals of apoptosis in CEL cells. We reviewed structural studies on CEL cells related to S100A8 and SFPQ. Particularly, this review highlighted microscopic results for the study of S100A8 and SFPQ in CEL cells.

• Journal of the Korean Data and Information Science Society
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• v.25 no.3
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• pp.655-663
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• 2014

This study aimed to investigate the prevalence of depression and suicidal ideation in community-dwelling older adults in Korea, as well as identify factors associated with their occurrence, including cognitive impairment. A cross-sectional study of 484 residents was conducted at a senior centre utilising the PHQ-9K and K-MMSE. Demographic data were also collected for analysis. Of the respondents, 38.1% had symptoms of mild to severe depression. Further, 16.7% reported having suicidal ideation, with 5% of respondents having thoughts of suicide every day. The majority of participants had 'normal' scores on the K-MMSE (88.0%), though significant differences were observed in PHQ-9K scores between cognitive-acceptable and cognitive-impaired groups. Depressive symptoms and suicidal ideation were very prevalent in community-dwelling older adults in Korea. This study indicates the need for the development of community-based mental health programs tailored to older adults, and demonstrates the viability of promoting early detection of depressive symptoms through senior centres.

• Journal of Korea Water Resources Association
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• v.33 no.S1
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• pp.937-942
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• 2000

• Journal of the Korean Home Economics Association
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• v.35 no.5
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• pp.61-72
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• 1997

The purpose of this study was to examine the developmental changes about self-perception from childhood to adult period. The subjects were 365 of 5th graders in elementary school, the 2nd graders in junior and senior high school, sophomore in college, and adults. The instruments used for this study were Harter's Self-Perception Profile for the children, adolescences, college students, and adults. The results were as follows. 1. From elementary school to junior high school, the score of scholastic, athletic, physical appearance, behavioral conduct, and global self-worth were decreased. At the developmental perspective, the junior high school students were highly anxious for self-perception. 2. Physical appearance were the best predictor of the global self-worth for all developmental stages. 3. Physical appearance, behavioral conduct predicted more about the global self-worth than any other factors for elementary and junior high school students. And for junior high school students, social acceptance and friendship also predicted about the global self-worth. Scholastic competence showed higher correlation with global self-worth for the senior high school and college students than elementary and junior high school students. 4. For college students, males had higer scores than females on ability-oriented but also relationship-oriented subscales. But the adults showed no differences in nurturance, household management, job competence depending on sex.

• Journal of Physiology & Pathology in Korean Medicine
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• v.20 no.2
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• pp.328-332
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• 2006

This study aims to provide definitions and standardization for necessities that elderly people can use conveniently and properly in their daily lives and classify necessities for different purposes. First, standard terminologies were defined by reviewing the literature and the relevant laws related to daily necessities for the elders. Secondly, a concept for necessities for the elders was also defined through consultation with experts. Lastly, the elderly's necessities were selected and classified. The elderly's necessities are defined as aids that ordinary elderly people in normal aging process need for the purpose of the convenience of life and aids they wear or use to maintain or improve their health. In this study, the elderly's necessities are divided into three categories: necessities of health, necessities of Oriental medical aids and necessities of daily living. Each category is further classified as follows: Necessities of health include aids for personal medical treatment, aids for personal care and protection and aids for recreation. Necessities of Oriental medical aids include aids for personal medical treatment, aids for personal care and protection and others. Necessities of daily living include aids for personal care and protection, aids for personal mobility, aids for housekeeping, furnishings, aids for communication, information and signalling, aids for handling products and goods and aids for recreation. The classification of the elderly's necessities in this study can be used as basic information for further studies of demand for necessities for the elderly. The results will lay the foundation for a standardization system for the elderly's necessities and the development of silver industry.

• Journal of Korea Game Society
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• v.11 no.2
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• pp.151-159
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• 2011

For the development of a curriculum of the serious game for the elderly in preparation of senior society, we have surveyed students of both college of humanity and college of engineering for their perception of importance and necessity on the subjects prepared by this team. We analyzed their common points and different points, and developed a new interdeciplinary curriculum for students in both college. The curriculum has been opened in the last semester successfully.

• Journal of the Korea Convergence Society
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• v.10 no.10
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• pp.357-369
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• 2019

This study was to examine the effects of simulation used additionally in clinical practicum and evaluate its applicability in an undergraduate nursing curriculum. A longitudinal survey was used to measure the changes on the scores of clinical competency, clinical confidence, critical thinking and problem solving ability of students(N=77) who had experienced simulation in the clinical practicum curricula throughout their junior and senior years. Variables were measured 4 times, at the beginning and the end of each year, and data were analyzed using repeated measures of ANOVAs. Clinical competency score in senior year improved significantly(t=-13.75, p<.001) whereas no significant changes in junior year. Clinical confidence and critical thinking disposition over 2 years showed significant increases(F=177.86, p<.001; F=247.79, p<.001, respectively). Problem solving ability increased throughout the junior and senior years, however, it did not make a significant difference at any point of measures.

• Journal of Korean society of Dental Hygiene
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• v.19 no.1
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• pp.65-78
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• 2019

Objectives: This study was conducted to characterize the impact of cognitive function and oral health status on mastication in senior citizens, ${\geq}65$ years of age, using senior centers in the city of Wonju, South Korea. Methods: A cross-sectional study consisting of a simple oral examination and survey questionnaires was performed in 154 individuals. General characteristics, subjective masticatory function, objective masticatory function, cognitive function, and oral health status were collected as variables. Correlation and multiple linear regression analyses were conducted. A p-value of <0.05 was considered to be statistically significant. Results: The subjective masticatory function was scored using the 5-point Likert scale. When subjective masticatory function was analyzed in groups according to cognitive function, the mean subjective masticatory function scores were 4.31, 4.09, and 3.29 in the normal group (cognitive score of ${\geq}16$), suspected dementia group (cognitive score of 1215), and mild dementia group (cognitive score of ${\leq}11$), respectively. Thus, subjective masticatory function decreased along with decreasing cognitive function. When cognitive function, subjective masticatory function, and objective masticatory function were compared with indicators of oral health status (number of functional teeth, oral dryness), subjective masticatory function exhibited a significant positive correlation with objective masticatory function (r=0.635, p<0.01), cognitive function (r=0.292, p<0.01), and total number of functional teeth, including prosthetic appliances (dentures) (r=0.305, p<0.01). According to the regression analysis, age, sex, number of functional teeth, and cognitive function affected subjective masticatory function. Conclusions: The results of this study revealed that age, sex, number of functional teeth, and cognitive function affected subjective masticatory function, whereas oral dryness did not. Therefore, dental professionals must consider subjective masticatory function when providing oral care in senior patients with low cognitive function.

• The Journal of Korean Academic Society of Nursing Education
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• v.27 no.1
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• pp.39-48
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• 2021

Purpose: This study aimed to explore factors influencing on the preventive behaviors of dementia in older Koreans enrolled in senior welfare centers to provide basic information on dementia prevention. Methods: A total of 182 older Koreans participated in this study, which employed a cross-sectional design. Data were collected using questionnaires with items related to general characteristics, depression, self-esteem, knowledge and attitudes about dementia, preventive behaviors of dementia, dementia management self-efficacy, and anxiety about dementia. Using SPSS WIN 23.0, data were analyzed by descriptive statistics, t-test, ANOVA, Scheffé test, Pearson's correlation coefficient, and multiple regression. Results: Living with a spouse (p=.013), a higher monthly income (p=.018), better nutrition (p=.010), not having a sleep disorder (p<.001), and higher number of participating programs (p=.001) were associated with better dementia prevention behaviors. Attitudes about dementia (��=.18, p=.006) and the number of programs older Koreans were participating in (��=.17, p=.006) influenced positively on the preventive behaviors of dementia, while depression (��=-.41, p<.001) and sleep disorders (��=-.17, p=.006) influenced negatively on dementia preventive behaviors. Overall, approximately 35% of the variability in dementia preventive behaviors was explained by these four variables in this study (F=24.97, p<.001). Conclusion: The findings of this study suggest that depression reduction, good attitudes about dementia, program participation, and good sleep should be encouraged to promote dementia prevention. In addition, effective and structured educational programs should be developed for older Koreans to encourage dementia preventive behaviors to reduce the risk of dementia.

• Korean Journal of Occupational Health Nursing
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• v.17 no.2
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• pp.117-125
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• 2008

Purpose: The purpose of the study was to find the ways to prevent the fatigue of the office of railroad employees. Method: The data were collected from the male employees of Korea Railroad Corporation. Results: The mean score of the degree of fatigue was 4.33. The factors that affected the level of fatigue were support from senior officials, exercise, age, work stress, number of work hours per week, alcohol intake and working area. To be more specific, the level of fatigue was lower when the support from senior officials was higher. The employees who did no exercise, who are in the age between 31 and 40, with high working stress, who worked 61 hours per week of higher, non-drinkers were found to have higher level of fatigue. The employees with the age of 51 years or older with unspecified work area had relatively lower level of fatigue. Conclusion: In conclusion, to decrease the level of fatigue of the office of railroad employees, the development of health improvement programs are required such as increase of the support from senior officials, change in exercise and drinking habit, decrease of the work stress and adjustment of the working hours.