• Journal of Platform Technology
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• 제12권1호
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• pp.12-31
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• 2024

Today, many countries around the world recognize the development of autonomous vehicles as a national growth engine, support technology development through various projects, and promote it as national policy. China and Korea are representative countries that are strongly promoting autonomous vehicle policies. The Chinese government's policy direction for self-driving cars focuses on support for fostering new industries. Korea has established mid- to long-term goals and plans to foster the future mobility industry as a key growth engine and is promoting these as a national task. Recently, China and Korea have established national pilot areas to test autonomous vehicle operation and are actively pursuing policies. We aim to compare and analyze the operation status of self-driving cars in China's Xiong'an New Area and South Korea's Sejong City and derive policy implications regarding self-driving cars, which are emerging as a key industry of the future. According to the analysis results, it was found that China's Xiong'an New District is ahead of Korea's Sejong City in terms of leader leadership. As a result, autonomous driving is being operated at the government-wide and national level in Xiong'an New Area. In terms of the driving force, in the case of Xiongan New Area, the policy is being promoted by companies centered on Baidu, and in the case of Sejong City, the policy is being promoted by the local government. As a result, it is estimated that Xiongan New Area will be able to reach commercialization before Sejong City. In the final policy proposal, it was proposed to break away from the existing government-led method and switch to a collaboration with the private sector and a private-led method.

• 한국생활과학회지
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• 제6권2호
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• pp.133-144
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• 1997

Clothing is considered as a means of self-projection in the childhood and children show clear preference on their own favorite clothing on which their latent identity is reflected. Changing sex-role identity, in particular, in the modern complex society specially affects the clothing behavior of children. The purpose of this study is to investigate the clothing behavior of children in conjunction with sen-role identity and home environment variables. This study will provide fundamental information on the clothing behavior in the childhood and be of help in selecting appropriate clothing in accordance with the variation of sex-role identity. Necessary information for this study was obtained through a questionaire. 'Bem sex-role identity inventory' was used to investigate the effect of sex-role identity and the clothing behavior was studied in conjunction with the factors of conformity, dependence, aesthetics and interest. The subjects of investigation are composed of three hundred male and female elementary school students in the 5th and 6th grades. For the statistical analysis of the collected data, percentage(%), mean value(M), standard deviation(SD) and Pearson's correlation coefficient were calculated and t-test, $x^2$-test, and Duncan's multiple range test were performed. The results form this study are as follows : 1. Sex-role identity shows a little difference according to gender, order of a birth and standard of living. This small difference is shown to be statistically insignificant. 2. In clothing behavior in connection with the sex-role identity, statistically significant trend was not found in typical sex-role identity group. However, clothing behavior in modernistic sex-role identity group exhibits statistically significant results in the factors of dependence, aesthetics and interest at the level of P<.001. 3. As concerns the clothing behavior in connection with gender, boy students show statistically more significant tendency in aesthetics and interest than girls do. However, boy students show statistically more significant tendency in aesthetics than girls do in connection with the standard of living. Although the clothing behavior associated with the level of parents education, mother's age and existence of mother's job shows a little difference in mean values, statistically significant trend was not detected. 4. Clothing behavior of the children shows a meaningful correlation between the factors. 5. Through 3-dimensional variables analysis, it is found that there is no mutual interaction between gender, sex-role identity and standard of living on the clothing behavior. The results from MCA supplementary analysis reveal that there is difference according to the gender, sex-role identity and standard of living.

• Journal of Ginseng Research
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• 제46권4호
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• pp.515-525
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• 2022

Background: The incidence of ischemic cerebrovascular disease is increasing in recent years and has been one of the leading causes of neurological dysfunction and death. Ginsenoside Rg1 has been found to protect against neuronal damage in many neurodegenerative diseases. However, the effect and mechanism by which Rg1 protects against cerebral ischemia-reperfusion injury (CIRI) are not fully understood. Here, we report the neuroprotective effects of Rg1 treatment on CIRI and its possible mechanisms in mice. Methods: A bilateral common carotid artery ligation was used to establish a chronic CIRI model in mice. HT22 cells were treated with Rg1 after OGD/R to study its effect on [Ca²⁺]_i. The open-field test and poleclimbing experiment were used to detect behavioral injury. The laser speckle blood flowmeter was used to measure brain blood flow. The Nissl and H&E staining were used to examine the neuronal damage. The Western blotting was used to examine MAP2, PSD95, Tau, p-Tau, NOX2, PLC, p-PLC, CN, NFAT1, and NLRP1 expression. Calcium imaging was used to test the level of [Ca²⁺]_i. Results: Rg1 treatment significantly improved cerebral blood flow, locomotion, and limb coordination, reduced ROS production, increased MAP2 and PSD95 expression, and decreased p-Tau, NOX2, p-PLC, CN, NFAT1, and NLRP1 expression. Calcium imaging results showed that Rg1 could inhibit calcium overload and resist the imbalance of calcium homeostasis after OGD/R in HT22 cells. Conclusion: Rg1 plays a neuroprotective role in attenuating CIRI by inhibiting oxidative stress, calcium overload, and neuroinflammation.

• International Journal of Industrial Entomology and Biomaterials
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• 제12권2호
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• pp.95-100
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• 2006

Central Sericultural Research and Training Institute, Mysore have evolved several highly productive bivoltine hybrids which can produce international grade raw silk. Among them $CSR2{\times}CSR4,\;CSR2{\times}CSR5,\;CSR3{\times}CSR6,\;CSR17{\times}CSR16,\;CSR18{\times}CSR19$ and $CSR12{\times}CSR6$ are being popularized in the field. There is a minimum difference in their economic characters but they appear to differ in survival. Though they are productive under high input management conditions, they are very susceptible to different diseases under normal rearing practices. No systematic attempts have been made to test their susceptibility status / resistance. Thus the present study is a modest attempt to screen the above six productive bivoltine hybrids to two important pathogens viz., Bombyx mori Nuclear Polyhedrosis Virus (BmNPV) and Bombyx mori Infectious Flacherie Virus (BmIFV) along with existing hybrid, $KA{\times}NB4D2$ to assess their susceptibility / resistance. The results shows that the productive hybrid $CSR2{\times}CSR4$ is the most resistant to BmNPV and it is suggested by its highest $LC_{50}$ value followed by $CSR12{\times}CSR6,\;KA{\times}NB4D2,\;CSR3{\times}CSR6,\;CSR17{\times}CSR16,\;CSR18{\times}CSR19,\;CSR2{\times}CSR5$. Based on the $LC_{50}$ value and $LT_{50}$ values for BmIFV, the hybrid $KA{\times}NB4D2$ was found to be the most resistant (1st position) one followed by $CSR3{\times}CSR6$ (2nd position) $CSR2{\times}CSR$ (3rd position) and $CSR12{\times}CSR6$ (4th position) $CSR17{\times}CSR16$, $CSR18{\times}CSR19$ (5th position) and $CSR2{\times}CSR5$ being the least. The response of 7 bivoltine hybrids to both the pathogens BmNPV and BmIFV indicates that, the hybrids $CSR2{\times}CSR4$, $CSR12{\times}CSR6$ and $KA{\times}NB4D2$ were found to be the most resistant when compared to others. Further, $KA{\times}NB4D2$ being less productive hybrid with a shell ratio of 20.08%, the other two hybrids $CSR2{\times}CSR4$ (Cocoon shell ratio, 21.44%) and $CSR12{\times}CSR6$ (cocoon shell ratio, 23.45%) can be considered to be most productive with superior quality cocoon and resistant to both BmNPV and BmIFV pathogens. The overall study indicated that the hybrid $CSR2{\times}CSR5$ is the most susceptible hybrid to both the pathogens.

• Journal of Preventive Medicine and Public Health
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• 제19권1호
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• pp.45-55
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• 1986

우리나라에서는 국면 10%정도가 B형간염환자나 보균자로 추정되고 있으며 매년 신생아에 있어서의 발병률과 보균자 접촉에 의한 신환자의 발생률이 증가하고 있는 실정이다. 이에 저자는 B형간염 바이러스 표면항원 검사 중 최근 널리 임상에서 이용되고 있는 역수신혈구응집법을 사용하며 일부 도시, 농촌, 해안지역 주민 2,849명을 대상으로 혈청내 간염 표면항원 양성률을 조사하여 연령별, 성별 역학적 인자와의 관계 및 세지역의 분포양상을 비교 분석하여 다음과 같은 결과를 얻었다. 1) 조사대상 2,849명 중242명이 양성을 나타내어 간염 표면항원 양성률은 8.49%였으며 남자가 9.07%, 여자가 6.79%로 남녀의 성비는 1.34 : 1이었다. 2) 지역별로는 도시지역의 8.67%, 농촌지역 7.43% 해안지역 8.37%로 도시, 해안, 농촌지역의 순이었으나 지역별로 유의한 차이는 없었다. 3) 성별로는 도시지역에서 남자 9.26%, 여자 6.44%로 남녀간에 유의한 차이를 보였으나 농촌, 해안지역에서는 남녀간에 비슷한 양성률을 보였다. 4) 연령별로는 도시에서 30대가 9.26%로 가장 높았으며 20대, 40대, 50대 순으로 나타났으며 농촌지역에서는 50대가 11.70%로 가장 높았고 해안지역에서는 30대와 40대에서 각각 10.94%로 가장 높았다. 전체적으로 남자에서는 20대, 30대, 40대 순으로 높고 연령이 증가하면서 감소하였고 여자에서는 50대에서 높은 양성률을 보였다. 5) 간염 표면항원 양성자 중 SGOT치가 정상보다 상승된 경우는 13.6%로 대부분 남자에서 나타났으며 음성자에서 상승된 경우인 3.4%보다 의의있게 높았다. 따라서 양성자의 대부분은 B형간염의 만성보균자, 급성바이러스 잠복기, 건강 보균자로 추정되었다.

• 대한수의학회지
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• 제46권4호
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• pp.337-345
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• 2006

The shigellae are common etiological agents of bacillary dysentery in humans and primates. During four years from 2002 to 2005, 22 strains of Shigella spp. were isolated from the diarrheic patients in Seoul region. All of them were identified as S. flexneri by biochemical tests and serotyping. The prevalence of serotypes were variable by year, but the major serotypes were 2a and 3a. In an antimicrobial susceptibility test, all of the isolates were resistant to streptomycin and tetracycline, and susceptible to amikacin, kanamycin, cefoxitin, and gentamicin. All of the isolates showed the multi-resistant patterns over 3 drugs. By analysis of the plasmid profile the isolates were classified into 7 groups (P1~P7). Serotypes 2a and 2b were distributed to P1, P2, P3, and P4. Serotype 3a was differentiated to P5 and serotype 3b, to P6 and serotype 4a, to P7. PCR results showed that all isolates were positive for two virulence genes, ipaH and ial, but none of the strains had stx gene. The set1A and set1B genes were detected from 12 isolates (54.5%) that belonged to serotype 2a and 2b. The sen gene was detected from 19 isolates (86.4%). The 22 isolates showed 12 to 17 DNA fragments in the sizes ranging from 20.5 kb to 1135 kb, resulting in 13 patterns by the PFGE with Not I digestion. The PFGE patterns of the isolates showed the close relation with the serotypes, but no relations with year of isolation and antimicrobial resistance.

• 한국지반공학회논문집
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• 제38권4호
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• pp.21-32
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• 2022

강재형 말뚝기초는 안정적인 지지력 확보와 높은 시공성으로 해양구조물 기초로 널리 활용되고 있다. 일반적으로 설계수명에 도달한 해양구조물은 해체수순을 밟게 되는데 말뚝기초는 높은 인발하중과 경제적인 이유로 예외적으로 현장에 존치되는 경우가 많다. 현장에 존치된 기초는 환경오염뿐만 아니라 신규구조물을 건설하는데 장애요인이 될 수 있으므로 말뚝기초 완전해체를 위한 연구가 필요한 실정이다. 본 연구에서는 인발하중을 획기적으로 저감시킬 수 있는 신형식 이중벽 말뚝기초를 제안하고 축소모형실험을 통해 인발하중 저감성능을 실험적으로 평가하였다. 이를 위해 축소된 이중벽 말뚝기초를 제작하고 건조된 모래지반에서 말뚝 설치 및 인발 거동을 모사하였으며, 측정된 인발하중을 동등한 단면의 일반말뚝과 비교하였다. 그 결과, 조밀한 모래지반에서 이중벽 말뚝의 최대 인발력이 일반말뚝에 비해 45% 감소되는 것을 확인하였다. 본 연구를 통해 이중벽 말뚝의 인발하중 저감 성능과 메커니즘을 검증하였으며, 설계수명에 도달한 기초를 완전히 회수할 수 있는 가능성을 확인하였다.

• Journal of Microbiology and Biotechnology
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• 제32권4호
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• pp.405-418
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• 2022

Simotang oral liquid (SMT) is a traditional Chinese medicine (TCM) consisting of four natural plants and is used to alleviate gastrointestinal side effects after chemotherapy and functional dyspepsia (FD). However, the mechanism by which SMT helps cure these gastrointestinal diseases is still unknown. Here, we discovered that SMT could alleviate gastrointestinal side effects after chemotherapy by altering gut microbiota. C57BL/6J mice were treated with cisplatin (DDP) and SMT, and biological samples were collected. Pathological changes in the small intestine were observed, and the intestinal injury score was assessed. The expression levels of the inflammatory factors IL-1β and IL-6 and the adhesive factors Occludin and ZO-1 in mouse blood or small intestine tissue were also detected. Moreover, the gut microbiota was analyzed by high-throughput sequencing of 16S rRNA amplicons. SMT was found to effectively reduce gastrointestinal mucositis after DDP injection, which lowered inflammation and tightened the intestinal epithelial cells. Gut microbiota analysis showed that the abundance of the anti-inflammatory microbiota was downregulated and that the inflammatory microbiota was upregulated in DDP-treated mice. SMT upregulated anti-inflammatory and anticancer microbiota abundance, while the inflammatory microbiota was downregulated. An antibiotic cocktail (ABX) was also used to delete mice gut microbiota to test the importance of gut microbiota, and we found that SMT could not alleviate gastrointestinal mucositis after DDP injection, showing that gut microbiota might be an important mediator of SMT treatment. Our study provides evidence that SMT might moderate gastrointestinal mucositis after chemotherapy by altering gut microbiota.

• 국제학술발표논문집
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• The 3th International Conference on Construction Engineering and Project Management
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• pp.869-875
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• 2009

Safety is a big issue in the construction sites. For safe and secure management, tracking locations of construction resources such as labors, materials, machineries, vehicles and so on is important. The materials, machineries and vehicles could be controlled by computer, whereas the movement of labors does not have fixed pattern. So, the location and movement of labors need to be monitored continuously for safety. In general, Global Positioning System(GPS) is an opt solution to obtain the location information in outside environments. But it cannot be used for indoor locations as it requires a clear Line-Of-Sight(LOS) to satellites Therefore, indoor location monitoring system could be a convenient alternative for environments such as tunnel and indoor building construction sites. This paper presents a case study to investigate feasibility of Wi-Fi based indoor location monitoring system in construction site. The system is developed by using fingerprint map of gathering Received Signal Strength Indication(RSSI) from each Access Point(AP). The signal information is gathered by Radio Frequency Identification (RFID) tags, which are attached on a helmet of labors to track their locations, and is sent to server computer. Experiments were conducted in a shield tunnel construction site at Guangzhou, China. This study consists of three phases as follows: First, we have a tracking test in entrance area of tunnel construction site. This experiment was performed to find the effective geometry of APs installation. The geometry of APs installation was changed for finding effective locations, and the experiment was performed using one and more tags. Second, APs were separated into two groups, and they were connected with LAN cable in tunnel construction site. The purpose of this experiment was to check the validity of group separating strategy. One group was installed around the entrance and the other one was installed inside the tunnel. Finally, we installed the system inner area of tunnel, boring machine area, and checked the performance with varying conditions (the presence of obstacles such as train, worker, and so on). Accuracy of this study was calculated from the data, which was collected at some known points. Experimental results showed that WiFi-based indoor location system has a level of accuracy of a few meters in tunnel construction site. From the results, it is inferred that the location tracking system can track the approximate location of labors in the construction site. It is able to alert the labors when they are closer to dangerous zones like poisonous region or cave-in..

• Korean Journal of Radiology
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• 제23권5호
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• pp.539-547
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• 2022

Objective: To investigate the association between functional tumor burden of peritoneal carcinomatosis (PC) derived from diffusion-weighted imaging (DWI) and overall survival in patients with advanced ovarian carcinoma (OC). Materials and Methods: This prospective study was approved by the local research ethics committee, and informed consent was obtained. Fifty patients (mean age ± standard deviation, 57 ± 12 years) with stage III-IV OC scheduled for primary or interval debulking surgery (IDS) were recruited between June 2016 and December 2021. DWI (b values: 0, 400, and 800 s/mm²) was acquired with a 16-channel phased-array torso coil. The functional PC burden on DWI was derived based on K-means clustering to discard fat, air, and normal tissue. A score similar to the surgical peritoneal cancer index was assigned to each abdominopelvic region, with additional scores assigned to the involvement of critical sites, denoted as the functional peritoneal cancer index (fPCI). The apparent diffusion coefficient (ADC) of the largest lesion was calculated. Patients were dichotomized by immediate surgical outcome into high- and low-risk groups (with and without residual disease, respectively) with subsequent survival analysis using the Kaplan-Meier curve and log-rank test. Multivariable Cox proportional hazards regression was used to evaluate the association between DWI-derived results and overall survival. Results: Fifteen (30.0%) patients underwent primary debulking surgery, and 35 (70.0%) patients received neoadjuvant chemotherapy followed by IDS. Complete tumor debulking was achieved in 32 patients. Patients with residual disease after debulking surgery had reduced overall survival (p = 0.043). The fPCI/ADC was negatively associated with overall survival when accounted for clinicopathological information with a hazard ratio of 1.254 for high fPCI/ADC (95% confidence interval, 1.007-1.560; p = 0.043). Conclusion: A high DWI-derived functional tumor burden was associated with decreased overall survival in patients with advanced OC.