• Asian-Australasian Journal of Animal Sciences
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• v.28 no.9
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• pp.1244-1251
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• 2015

A herd of Berkshire pigs was established in 2003 and subjected to selection without introduction of any genetic resources until 2007. The complete pedigree, including 410 boars and 916 sows, as well as the records from 5,845 pigs and 822 litters were used to investigate the results obtained from the selections. The index of selection for breeding values included days to 90 kg (D90kg), backfat thickness (BF) and number of piglets born alive (NBA). The average inbreeding coefficients of pigs were found to be 0.023, 0.008, 0.013, 0.025, 0.026, and 0.005 from 2003 to 2007, respectively. The genetic gains per year were 12.1 g, -0.04 mm, -3.13 days, and 0.181 head for average daily gain (ADG), BF, D90kg, and NBA, respectively. Breeding values of ADG, BF and D90kg were not significantly correlated with inbreeding coefficients of individuals, except for NBA (-0.21). The response per additional 1% of inbreeding was 0.0278 head reduction in NBA. The annual increase of inbreeding was 0.23% and the annual decrease in NBA due to inbreeding was 0.0064 head. This magnitude could be disregarded when compared with the annual gain in NBA (0.181 head). These results suggest that inbreeding and inbreeding depression on ordinary farms can be controlled with a proper breeding scheme and that breeding programs are economical and safe relative to the risks associated with importation of pigs.

• CELLMED
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• v.5 no.1
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• pp.6.1-6.10
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• 2015

Fumaria indica Linn. (Syn: Fumaria parviflora, Fumariaceae) is a wildly grown weed, mentioned and recommended in classical Ayurvedic texts for treatments of variety of ailments including dermatological diseases, topical diseases, cardiovascular complaints, circulatory disease, fever and headache etc. The present pilot study was designed to experimentally verify the possibility that fumarates are the major bioactive principles of Fumaria indica extracts involved in their stress response modulating activities, and to estimate pharmacologicallyactive dose ranges of fumarates and standardized methanolic extract of Fumaria indica (MFI). Effect of single, 5 and 10 daily oral doses of pure fumaric acid (FA), monomethyl fumarate (MMF), dimethyl fumarate (DMF) and MFI was quantified in well validated rodent models viz. apomorphine induced cage climbing, stress induced hyperthermia, and elevated plus-maze tests. Obtained results reveal high efficacy of MFI and pure fumarates possess qualitatively analogous activity profiles in all the three tests. There were no significant difference in the potencies of pure FA, MMF and DMF in the three tests, whereas efficacy of MFI in the elevated plus maze test for anxiolytics was higher than in the other two tests. Efficacies of all the four test agents in all the three tests increased with increasing number of days of oral treatments. Results of these pilot experiments should be helpful for more rational selections of pharmacologically interesting dose ranges and treatment regimens of fumarates and Fumaria indica extracts for further more holistic explorations of their diverse therapeutic potentials.

• The Journal of the Korea Contents Association
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• v.16 no.10
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• pp.676-686
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• 2016

This study explored the development and applicability of a classics book reading program in the nursing curriculum as a character education program in order to enhance nursing students' holistic growth and development. An increasing number of universities in Seoul have introduced a classics book reading program as part of the curriculum and some have even designated it as an essential subject. Various such programs have been developed in addition to the regular education curriculum. The following aspects are important to consider in a classics book reading program for nursing students: trust, respect, responsibility, fairness, caring, citizenship, endurance, healthy self-concept, and self-sustained growth performance. Classics book selections need to take into account the level of the students, and the efforts should be made to ensure the accuracy of the translation and the level of students' understanding. It is difficult to form character through short-term education. Despite difficulties, character formation requires continued interest and systemic education that will lead nursing students to show inbuilt positive characteristics. Inclusion of character education in the nursing curriculum should be considered with the agreement of the university, based on political decision-making.

• Proceedings of the Korean Radioactive Waste Society Conference
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• 2004.02a
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• pp.220-237
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• 2004

China, as a developing country with a great number of population and relatively less energy resources, reasonably emphasizes the nuclear energy utilization development. For the long term sustainable energy supply, as for nuclear application the basic strategy of PWR-FBR-Fusion has been settled and envisaged. Due to the economy and experience reasons the nuclear power and technology development with a moderate style are kept in China up to now. In China mainland apart from two NPPs with the total capacity of 2.1 GWe in operation, four NPPs are under construction and two NPPs are planned for the Tenth Five Year Plan(2001-2005). Also another one or two NPPs are still in discussion. It could be foreseen that the total nuclear power capacity will reach 8.5GWe before the year 2005 and 14-15 GWe before 2010 respectively. As the first step for the Chinese fast reactor engineering development the 65MWt China Experimental Fast Reactor(CEFR) is under construction. The main components of primary, secondary and tertiary circuits and of fuel handling system have been ordered. The reactor building under construction has reached the top namely 57m above the ground. More than one hundred components and shielding doors have been installed. It is planned that the construction of reactor building with about 40,000$m^2$ floor surface will be completed in the end of the year 2002 and envisaged that the first criticality of the CEFR will be in the end of 2005. The second step of the Chinese fast reactor engineering development is a 300MWe Prototype Fast Breeder Reactor which is only under consideration up to now. Some important technical selections have been settled, but its design has not yet started.

• Reproductive and Developmental Biology
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• v.39 no.4
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• pp.105-115
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• 2015

Toll-like receptor 7 (TLR7) is critical for the triggering of innate immune response by recognizing the conserved molecular patterns of single-stranded RNA (ssRNA) viruses and mediated antigenic adaptive immunity. To understand how TLR7 distinguish pathogen-derived molecular patterns from the host self, it is essential to be able to identify TLR7 receptor interaction interfaces, such as active sites or R848-agonist binding sites. The functional interfaces of TLR7 can serve as targets for structure-based drug design in studying the TLR7 receptor's structure-function relationship. In contrast to mammalian TLR7, chicken TLR7 (chTLR7) is unknown for its important biological function. Therefore, it has been targeted to mediate contrasting evolutionary patterns of positive selection into non-synonymous SNPs across eleven species using TLR7 conservation patterns (evolutionary conserved and class-specific trace residues), where protein sequence differences to the TLR7 receptors of interest record mutation that have passed positive section across the species. In this study, we characterized the Lys609 residue on chTLR7-ECD homodimer interfaces to reflect the current tendency of evolving positive selection to be transfer into a stabilization direction of the R848-agonist/chTLR7-ECDs complex under the phylogenetically variable position across species and we suggest a potential indicator for contrasting evolutionary patterns of both the species TLR-ECDs.

• Journal of KIISE:Software and Applications
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• v.36 no.10
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• pp.816-824
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• 2009

In the face space, face images due to illumination and pose variations have a nonlinear distribution. Active Appearance Models (AAM) based on the linear model have limits to the nonlinear distribution of face images. In this paper, we assume that a few clusters of face images are given; we build local AAMs according to the clusters of face images, and then select a proper AAM model during the fitting phase. To solve the problem of updating fitting parameters among the models due to the model changing, we propose to build in advance relationships among the clusters in the parameter space from the training images. In addition, we suggest a gradual model changing to reduce improper model selections due to serious fitting failures. In our experiment, we apply the proposed model to Yale Face Database B and compare it with the previous method. The proposed method demonstrated successful fitting results with strongly illuminated face images of deep shadows.

• Proceedings of the Korean Society for Applied Microbiology Conference
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• 2000.04a
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• pp.178-181
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• 2000

In order to develop the novel gene expression system, we introduced new control elements which could influence the foreign gene expression in animal cells. When the foreign genes are introduced into the genome of higher eukaryotic cells, the expressions from these integrated genes are often low and can vary greatly depending on the positions of the integration sites due to the complex nature of the chromatin structures (1). First we screened the various DNA sequence elements which can function as an insulator of gene expression from these position effects and can cooperate with the SV40 enhancer/promoter. Among the several DNA elements from the various sources, we identified the particular DNA element which confers the increased frequency of the positive colonies, assayed by the reporter gene from stable selections indicating significantly reduced position effects. This element also showed the several fold-increased expression level as well as the copy-number dependent expression with host cell specificity. Second we modified the transcription termination element where we introduced the specific terminator in combination with SV40 polyA signal. This modified terminator showed the increased efficiency and the level of the gene expression. By combining these two elements, we made the animal cell expression system and tested successfully for the recombinant protein productions of TGF ${\beta}$-soluble receptor, Antithrombin III, and single chain Pro-Urokinase. [Supported by grants from MOCIE]

• The KIPS Transactions:PartB
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• v.9B no.1
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• pp.29-34
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• 2002

Fingerprint recognition technology was studied by classification and matching. In general, there are five different classifications left loop, right loop, whore, arch, and tented-arch. These classifications are used to determine which class an individual's fingerprint belong to, thereby identifying the individual's fingerprint pattern. The result of this classification, which is sent to the large fingerprint database as an index, helps reduce the matching time and enhance the accuracy of fingerprint matching. The existing fingerprint classification method relies on the number and location of cores and delta points called singular points. The drawback of this method is the lack of accuracy stemming from the classification difficulty involving unclear and/or partially-erased fingerprints. The current paper presents an efficient classification method to rectify the problem associated with identifying Singular points from unclear fingerprints. This method, which is based on Gabor filter's unique characteristics for magnifying directional patterns and frequency range selections, improves fingerprint classification accuracy significantly. In this paper, this method is described and its test result is presented for verification.

• Journal of Korean Library and Information Science Society
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• v.48 no.2
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• pp.215-236
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• 2017

The purpose of this study is to develop an automatic classification system for recommending appropriate books of 9 enneagram personality types, using book information data reviewed by librarians. Data used for this study are book review of 501 recommended titles for children and young adults from National Library for Children and Young Adults. This study is implemented on the assumption that most people prefer different types of books, depending on their preference or personality type. Performance test for two different types of machine learning models, nonlinear kernel and linear kernel, composed of 360 clustering models with 6 different types of index term weighting and feature selections, and 10 feature selection critical mass were experimented. It is appeared that LIBLINEAR has better performance than that of LibSVM(RBF kernel). Although the performance of the developed system in this study is relatively below expectations, and the high level of difficulty in personality type base classification take into consideration, it is meaningful as a result of early stage of the experiment.

• 한국태양에너지학회:학술대회논문집
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• 2009.04a
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• pp.235-240
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• 2009

Crystlline silicon solar cells markets are increasing at rapid pace. now, crystlline silicon solar cells markets screen-printing solar cell is occupying. screen-printing solar cells manufacturing process are very quick, there is a strong point which is a low cost. but silicon and metal contact, uses Ag & Al pates. because of, high contact resistance, high series resistance and sintering inside process the electric conductivity decreases with 1/3. and In pastes ingredients uses Ag where $80{\sim}90%$ is metal of high cost. because of low cost solar cells descriptions is difficult. therefore BCSC(Buried Contact Solar Cell) is developed. and uses light-induced plating, ln-line galvanization developed equipments. Ni/Cu matel contact solar cells researches. in Germany Fraunhofer ISE. In order to manufacture high-efficiency solar cells, metal selections are important. metal materials get in metal resistance does small, to be electric conductivity does highly. efficiency must raise an increase with rise of the curve factor where the contact resistance of the silicon substrate and is caused by few with decrement of series resistance. Ni metal materials the price is cheap, Ti comes similar resistance. Cu and Ag has the electric conductivity which is similar. and Cu price is cheap. In this paper, Ni/Cu/Ag metal contact cell with screen printing manufactured, silicon metal contact comparison and analysis.