• 제목/요약/키워드: Selection factor

검색결과 1,858건 처리시간 0.026초

Low Levels of Polymorphisms and Negative Selection in Plasmodum knowlesi Merozoite Surface Protein 8 in Malaysian Isolates

  • Ahmed, Md Atique;Kang, Hae-Ji;Quan, Fu-Shi
    • Parasites, Hosts and Diseases
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    • 제57권4호
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    • pp.445-450
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    • 2019
  • Human infections due to the monkey malaria parasite Plasmodium knowlesi is increasingly being reported from most Southeast Asian countries specifically Malaysia. The parasite causes severe and fatal malaria thus there is a need for urgent measures for its control. In this study, the level of polymorphisms, haplotypes and natural selection of full-length pkmsp8 in 37 clinical samples from Malaysian Borneo along with 6 lab-adapted strains were investigated. Low levels of polymorphism were observed across the full-length gene, the double epidermal growth factor (EGF) domains were mostly conserved, and non-synonymous substitutions were absent. Evidence of strong negative selection pressure in the non-EGF regions were found indicating functional constrains acting at different domains. Phylogenetic haplotype network analysis identified shared haplotypes and indicated geographical clustering of samples originating from Peninsular Malaysia and Malaysian Borneo. This is the first study to genetically characterize the full-length msp8 gene from clinical isolates of P. knowlesi from Malaysia; however, further functional characterization would be useful for future rational vaccine design.

The Structural Relationship among Selection Attributes, Consumption Value Brand Attitude, Fun, Brand Loyalty and Quality of Life in Athleisure

  • Byun, Kyung-Won;Kim, Moo-Young
    • International journal of advanced smart convergence
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    • 제10권2호
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    • pp.138-144
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    • 2021
  • The purpose of this study is to analyze the relationship among selection attributes, consumption value brand attitude, fun, brand loyalty and quality of life. The subjects of the empirical study were selected by the Korea Fashion Industry Research Institute using the convention sampling method and the quota sampling method for 241 consumers who have purchased brands classified as "athleisure" within the past year For each variable constructed to verify reliability and validity of the measurement model, reliability tests using Cronbach' alpha were performed using IBM SPSS Win Ver. 23.0. To verify the unidimensionality of the measurements, we conducted a confirmatory factor analysis using AMOS 22.0 and a structural equation model to determine the structural relationship between variables. As a result of the study, First, both intrinsic and extrinsic attributes, which are sub-factors of selection attributes, have been shown to have a significant effect on consumption value. Second, consumption value has been shown to have a significant impact on brand attitude and fun. Third, brand attitudes have been shown to have a significant impact on brand loyalty. Finally, fun has been shown to have a significant impact on quality of life.

Location Selection of an LNG Bunkering Port in Korea

  • Lu, Wen;Seo, Jeong-Ho;Yeo, Gi-Tae
    • Journal of Korea Trade
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    • 제23권2호
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    • pp.59-75
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    • 2019
  • Purpose - The International Maritime Organization (IMO) has promulgated strict regulations on emissions in the maritime shipping industry. LNG (Liquefied Natural Gas) is, therefore, recognized as the optimal fuel alternative solution. The aim of this study is to select the most suitable location for an LNG bunkering port. This is formulated as a multiple-criteria ranking problem regarding four candidate ports in South Korea: the ports of Busan, Gwangyang, Incheon, and Ulsan. Design/Methodology/approach - An analysis employing the Consistent Fuzzy Preference Relation (CFPR) methodology is carried out, and the multiple-criteria evaluation of various factors influencing the location selection, such as the average loading speed of LNG, the number of total ships, the distance of the bunkering shuttle, and the degree of safety is performed. Then, based on the combination of both the collected real data and experts' preferences, the final ranking of the four ports is formulated. Findings - The port of Busan ranks first, followed by the ports of Gwangyang and Ulsan, with the port of Incheon last on the list. Originality/value - The Korean government could proceed with a clear vision of the candidate ports' ranking in terms of the LNG bunkering terminal selection problem.

LIFT CYCLE PREDICTION METHOD FOR THE SELECTION OF LIFT EQUIPMENT IN SUPER TALL BUILDING CONSTRUCTION

  • Seo-kyung Won;Choong-hee Han;Junbok Lee
    • 국제학술발표논문집
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    • The 3th International Conference on Construction Engineering and Project Management
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    • pp.153-160
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    • 2009
  • The demand for super tall building construction is increasing worldwide. There has been a constant request for achieving early payback on investment by shortening the construction time. This pertains especially for the case of huge investment projects such as super tall building construction. It is very important to shorten the construction time for the building framework, which requires substantial construction time and cost, and this is directly related to the establishment of an optimum lift plan for construction. When there is a problem in the selection of the lift equipment, it is almost impossible to revise the selection, resulting in a possible failure of the project. Thus, the purpose of this study is to analyze the function and logic for the development of the process for the selection of lift equipment for super tall building projects and further development of making the analyzed process into a system. In line with this research objective, the process of selecting the optimum lift equipment by domestic construction company was investigated and analyzed as well as collecting the actual field data. The actual data were obtained by sensors installed on tower cranes at three construction sites with the help from the construction company.

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The Effect of Selection Attributes of Public Delivery Apps and Support for Public Institutions on the Intention of Restaurant Service Providers to Use Public Delivery Apps

  • Se-Yong Kwon;Li-Ping Yu;Hyung-Ho Kim
    • International journal of advanced smart convergence
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    • 제12권1호
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    • pp.173-183
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    • 2023
  • Recently, local governments that provide mobile-based public delivery app services have been increasing a lot. The purpose of this study is to analyze whether the restaurant self-employed's public delivery app selection attributes and public institutions' perception of support, which are under economic pressure due to the high delivery fee burden of private delivery apps, affect the intention to use public delivery app services. In this study, the degree of perception of each factor was measured using the Likert 5-point scale, and it was verified through statistical analysis using SPSS. The effect of the selection attribute of public delivery apps and the perception of self-employed people in the restaurant industry on the intention to use the service was empirically analyzed, and the hypothesis was verified using regression analysis. As a result of this study, it was confirmed that convenience, economy, and public interest had a significant effect among the factors of public app selection attributes, and educational support had a significant effect on public institution support.

중국 닝샤 와이너리 방문동기와 선택속성에 관한 연구 (A Study on the Motivation and Choice Attributes of Visiting Wineries in Ningxia, China)

  • 이수현;우원석;황재현
    • 한국유기농업학회지
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    • 제32권1호
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    • pp.39-54
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    • 2024
  • This study aimed to elucidate the relationship between the selection attributes and visit motivations of Ningxia wineries and tourist satisfaction and intention to revisit. Utilizing multiple linear regression and simple linear regression models, the study quantitatively analyzed tourists' selection attributes and visit motivations for Ningxia wineries. Factor analysis categorized 12 visit motivation variables into four factors: 'Sensation', 'Educational', 'Companion-Friendly', and 'Experiential'. Additionally, 17 selection attribute variables were classified into four factors: 'Service Quality', 'Environmental', 'Facility', and 'Economic'. Through analyzing the impact of visit motivations on satisfaction and revisit intentions, we have identified the pivotal factors as 'Wine Cultural Education', 'Enhanced Companion-Friendliness', and 'Wine Cultural Experience'. In the analysis of the relationship between selection attributes and revisit intentions, crucial elements involve 'Service Quality provided by the winery"'and 'Environmental of the winery'. Conversely, key influencing revisit intentions include 'Environmental of the winery' and 'Costs and Pricing associated with winery visits'. To ensure the sustainable development of the Ningxia winery industry and promote the enduring growth of rural economies, wineries should place greater emphasis on cultivating wine cultural experiences, artisanal activities, and other project endeavors.

Screening of High-Productivity Cell Lines and Investigation of Their Physiology in Chinese Hamster Ovary (CHO) Cell Cultures for Transforming Growth $Factor-{\beta}1$ Production

  • Chun, Gin-Taek;Lee, Joo-Buom;Nam, Sang-Uk;Lee, Se-Won;Jeong, Yeon-Ho;Choi, Eui-Yul;Kim, Ik-Hwan;Jeong, Yong-Seob;Kim, Pyeong-Hyeun
    • Journal of Microbiology and Biotechnology
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    • 제12권1호
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    • pp.121-129
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    • 2002
  • Using recombinant Chinese hamster ovary (CHO) cells, strategies for developing high producers for the recombinant human Transforming Growth $Factor-{\beta}1$ ($TGF-{\beta}1$) protein are proposed and their physiological characteristics in cell cultures were investigated. $TGF-{\beta}1$ is a pleiotrophic polypeptide involved in various biological activities, including cell growth, differentiation, and deposition of extracellular matrix proteins. The CHO cells included human $TGF-{\beta}1$ cDNA in conjunction with a dihydrofolate reductase (DHFR) gene, which was cotransfected into the cells to amplify the transfected $TGF-{\beta}1$ cDNA. As a first-round screening of the transfected cells, a relatively high $TGF-{\beta}1$-producing cell line was selected, and then, it acquired a resistance to increasing concentrations of methotrexate (MTX) up to $60{\mu}M$,resulting in a significant improvement in its $TGF-{\beta}1$ biosynthetic ability. After applying a monoclonal selection strategy to the MTX-resistant cells, more productive cells were screened, including the APP-3, App-5, and App-8 cell lines. These high producers were compared with two other cell lines (AP-l cell line without amplification of transfected $TGF-{\beta}1$ cDNA and nontransfectant of $TGF-{\beta}1$ cDNA) in terms of cell growth, $TGF-{\beta}1$ productivity, sugar uptake, and byproduct formation, in the presence or absence of MTX in the culture medium. Consequently, both monoclonal selection as well as an investigation of the physiological characteristics were found to be needed for the efficient screening of higher $TGF-{\beta}1$ producers, even after the transfection and amplification of the transfected gene.

CFPR법을 활용한 국내 화주기업의 3PL 기업 선정 요인에 관한 연구 (A Study on the Factors of Selecting 3PL Companies by Using CFPR Method in Korea)

  • 강래현;양태현;이해찬;박성훈;여기태
    • 디지털융복합연구
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    • 제18권5호
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    • pp.169-178
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    • 2020
  • 경쟁력 있는 물류서비스를 제공받고자 하는 화주기업에게 3PL 기업의 선택은 중요한 과정이다. 하지만 소비자인 화주기업의 관점에서 3PL 기업을 선정하는데 영향을 미치는 요인을 분석한 연구는 부족한 상황이다. 이러한 측면에서 본 연구는 전문가의 지식을 효율적으로 추출하여 계량화할 수 있는 CFPR (Consistent Fuzzy Preference Relations) 방법을 활용하여 국내 화주기업이 3PL 기업을 선정할 때 활용하는 요인을 추출하고, 요인별 가중치를 제시하는 것을 연구의 목적으로 하였다. 분석결과 대요인은 "운영요인"이 가장 중요한 것으로 나타났으며, 다음으로는 "전략적 요인", 마지막으로 "의사소통 요인"이 중요한 것으로 나타났다. 복합 가중치의 결과를 살펴보면 "비용절감"이 가장 중요한 요인으로 나타났으며, "업체의 전문성", "재고관리능력", "인적자원관리" 등의 순으로 나타났다. 본 연구는 화주사 측면에서 3PL 기업을 선정할 때 고려하여야 하는 핵심요소를 제시하였으며, 3PL 기업 측면에서는 화주사가 중요하게 고려하는 요인들을 강화하여 향후 화주사의 만족도를 향상시킬 수 있는 기초자료를 제공하였다는 점에 산업적인 시사점이 있다. 향후연구에서는 화주를 산업별로 구분하고, 각 산업별 화주사가 3PL 기업 선정할 때 발생하는 요인의 차이점을 분석할 필요가 있다.

AHP를 활용한 노후 공동주택의 재건축과 리모델링의 사업선택결정에 관한 연구 (A Study on Reconstruction and Remodeling's Selection Factors of Old Apartment Houses Using AHP)

  • 손성현;유승민;이기석;최윤기
    • 한국건설관리학회논문집
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    • 제16권6호
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    • pp.12-21
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    • 2015
  • 1970년대 중반 이후 건립된 노후 공동주택 단지들에 대한 재정비 사업의 일환으로 재개발과 리모델링이 도입되었고 각 사업의 활성화를 위한 정부의 정책도 지속적으로 변화해왔다. 하지만 정책의 빈번한 변화는 사업 방식을 선택하는데 있어서 사업 주체간의 갈등과 대립을 야기 시켰고 이러한 사업 초기 단계부터의 갈등은 사업의 전체적인 진행에 차질을 주었다. 따라서 이러한 갈등을 해결하기 위하여 재건축과 리모델링의 장단점을 고려한 합리적인 사업 선택 모델 구축이 필요하게 되었다. 이에 본 연구에서는 재건축과 리모델링의 사업을 선택함에 있어서 어떠한 요소들이 얼마나 영향을 미치는지에 대하여 알아보기 위하여 두 사업에 대한 비교 분석을 통해 사업 선택 요소를 도출하였고 전문가들을 통한 적정성 검증으로 4개 분야 26항목의 선택요소들을 최종 선별하였다. 이후 AHP 기법을 이용하여 각 선택 요소가 재건축과 리모델링 사업선택에 미치는 상대적 중요도 및 영향값을 분석하여 우선순위를 도출하였다. 이처럼 재건축과 리모델링의 사업선택 요소에 대한 영향력 분석을 통해 얻은 결론을 바탕으로 여러 사례검증을 통한 연구를 지속적으로 진행하여 소유자들간의 갈등을 해결하고 사업을 합리적인 방향으로 선택 할 수 있기를 기대한다.

Shannon 엔트로피 개념을 이용한 가보 웨이블렛 최적 형상의 선정 (The Selection of the Optimal Gator Wavelet Shape Factor Using the Shannon Entropy Concept)

  • 홍진철;김윤영
    • 한국소음진동공학회:학술대회논문집
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    • 한국소음진동공학회 2002년도 추계학술대회논문집
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    • pp.176-181
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    • 2002
  • The continuous Gabor wavelet transform (GWT) has been utilized as a useful time-frequency analysis tool to identify the rapidly-varying characteristics of some wave signals. In the application of GWT, it is important to select the Gabor wavelet with the optimal shape factor by which the time-frequency distribution of a signal can be accurately estimated. To find the signal-dependent optimal Gabor wavelet shape factor, the notion of the Shannon entropy which mesures the extent of signal energy concentration in the time-frequency plane is employed. To verify the validity of the present entropy-based scheme, we have applied it to the time-frequency analysis of a set of elastic bending wave signals generated by an impact in a solid cylinder.

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