• Proceedings of the Microbiological Society of Korea Conference
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• 2006.05a
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• pp.129-131
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• 2006

Through molecular phylogenetic analysis using the nef gene sequences of HIV-l isolated from Korean registered in the NCBI GenBank together with 41 reference strains and 94 foreign isolates, we verified that most (${\sim}80%$) of Korean isolates belonged to subtype B and 78% of subtype B were clustered together exclusively of foreign isolates, and this cluster was named Korean clade subtype B ($K_cB$). Similarity study suggested that the $K_cB$ cluster was more homogeneous than and clearly distinctive from the non-Korean subtype B ($NK_cB$). Comparison of the consensus amino acid sequences of the $K_cB\;or\;NK_cB$ revealed characteristic $K_cB$ signature amino acid pattern comprised of 13 amino acid residues. The $K_cB$ signature amino acid residues were critical in separating the $K_cB$ ftom the $NK_cB$, since substitution of the $NK_cB$ sequences with $K_cB$ signature amino acids relocated them to the Koran clade, and vice versa. Synonymous and nonsynonymous substitution rate study suggested positive selection event for the $K_cB$.

• Journal of Information Processing Systems
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• v.10 no.4
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• pp.555-567
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• 2014

Biometric performance improvement is a challenging task. In this paper, a hierarchical strategy fusion based on multimodal biometric system is presented. This strategy relies on a combination of several biometric traits using a multi-level biometric fusion hierarchy. The multi-level biometric fusion includes a pre-classification fusion with optimal feature selection and a post-classification fusion that is based on the similarity of the maximum of matching scores. The proposed solution enhances biometric recognition performances based on suitable feature selection and reduction, such as principal component analysis (PCA) and linear discriminant analysis (LDA), as much as not all of the feature vectors components support the performance improvement degree.

• Asian-Australasian Journal of Animal Sciences
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• v.26 no.5
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• pp.603-608
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• 2013

Hanwoo have been subjected over the last seventy years to intensive artificial selection with the aim of improving meat production traits such as marbling and carcass weight. In this study, we performed a signature of selection analysis to identify recent positive selected regions driven by a long-term artificial selection process called a breeding program using whole genome SNP data. In order to investigate homozygous regions across the genome, we estimated iES (integrated Extended Haplotype Homozygosity SNP) for the each SNPs. As a result, we identified two highly homozygous regions that seem to be strong and/or recent positive selection. Five genes (DPH5, OLFM3, S1PR1, LRRN1 and CRBN) were included in this region. To go further in the interpretation of the observed signatures of selection, we subsequently concentrated on the annotation of differentiated genes defined according to the iES value of SNPs localized close or within them. We also described the detection of the adaptive evolution at the molecular level for the genes of interest. As a result, this analysis also led to the identification of OLFM3 as having a strong signal of selection in bovine lineage. The results of this study indicate that artificial selection which might have targeted most of these genes was mainly oriented towards improvement of meat production.

• Asian-Australasian Journal of Animal Sciences
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• v.33 no.9
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• pp.1378-1386
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• 2020

Objective: Chinese indigenous sheep breeds can be classified into the following three categories by their tail morphology: fat-tailed, fat-rumped and thin-tailed sheep. The typical sheep breeds corresponding to fat-tailed, fat-rumped, and thin-tailed sheep are large-tailed Han, Altay, and Tibetan sheep, respectively. Detection of copy number variation (CNV) and selection signatures provides information on the genetic mechanisms underlying the phenotypic differences of the different sheep types. Methods: In this study, PennCNV software and F-statistics (F_ST) were implemented to detect CNV and selection signatures, respectively, on the X chromosome in three Chinese indigenous sheep breeds using ovine high-density 600K single nucleotide polymorphism arrays. Results: In large-tailed Han, Altay, and Tibetan sheep, respectively, a total of six, four and 22 CNV regions (CNVRs) with lengths of 1.23, 0.93, and 7.02 Mb were identified on the X chromosome. In addition, 49, 34, and 55 candidate selection regions with respective lengths of 27.49, 16.47, and 25.42 Mb were identified in large-tailed Han, Altay, and Tibetan sheep, respectively. The bioinformatics analysis results indicated several genes in these regions were associated with fat, including dehydrogenase/reductase X-linked, calcium voltage-gated channel subunit alpha1 F, and patatin like phospholipase domain containing 4. In addition, three other genes were identified from this analysis: the family with sequence similarity 58 member A gene was associated with energy metabolism, the serine/arginine-rich protein specific kinase 3 gene was associated with skeletal muscle development, and the interleukin 2 receptor subunit gamma gene was associated with the immune system. Conclusion: The results of this study indicated CNVRs and selection regions on the X chromosome of Chinese indigenous sheep contained several genes associated with various heritable traits.

• KIISE Transactions on Computing Practices
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• v.24 no.2
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• pp.99-104
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• 2018

Recently, there are increasing damages by ransomware in the world. Ransomware is a malicious software that infects computer systems and restricts user's access to them by locking the system or encrypting user's files saved in the hard drive. Victims are forced to pay the 'ransom' to recover from the damage and regain access to their personal files. Strong countermeasure is needed due to the extremely vicious way of attack with enormous damage. Malware analysis method can be divided into two approaches: static analysis and dynamic analysis. Recent malwares are usually equipped with elaborate packing techniques which are main obstacles for static analysis of malware. Therefore, this paper suggests a dynamic analysis method to monitor activities of ransomware. The proposed method can analyze ransomwares more accurately. The suggested method is comprised of extracting signatures of benign program, malware, and ransomware, and selecting the most appropriate signatures for ransomware detection.

• Animal Bioscience
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• v.37 no.3
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• pp.461-470
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• 2024

Objective: The objective of this study was to investigate the genetic diversity, population structure and whole-genome selection signatures of Luxi cattle to reveal its genomic characteristics in terms of meat and carcass traits, skeletal muscle development, body size, and other traits. Methods: To further analyze the genomic characteristics of Luxi cattle, this study sequenced the whole-genome of 16 individuals from the core conservation farm in Shandong region, and collected 174 published genomes of cattle for conjoint analysis. Furthermore, three different statistics (pi, F_st, and XP-EHH) were used to detect potential positive selection signatures related to selection in Luxi cattle. Moreover, gene ontology and Kyoto encyclopedia of genes and genomes pathway enrichment analyses were performed to reveal the potential biological function of candidate genes harbored in selected regions. Results: The results showed that Luxi cattle had high genomic diversity and low inbreeding levels. Using three complementary methods (pi, F_st, and XP-EHH) to detect the signatures of selection in the Luxi cattle genome, there were 2,941, 2,221 and 1,304 potentially selected genes identified, respectively. Furthermore, there were 45 genes annotated in common overlapping genomic regions covered 0.723 Mb, including PLAG1 zinc finger (PLAG1), dedicator of cytokinesis 3 (DOCK3), ephrin A2 (EFNA2), DAZ associated protein 1 (DAZAP1), Ral GTPase activating protein catalytic subunit alpha 1 (RALGAPA1), mediator complex subunit 13 (MED13), and decaprenyl diphosphate synthase subunit 2 (PDSS2), most of which were enriched in pathways related to muscle growth and differentiation and immunity. Conclusion: In this study, we provided a series of genes associated with important economic traits were found in positive selection regions, and a scientific basis for the scientific conservation and genetic improvement of Luxi cattle.

• International Journal of Costume and Fashion
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• v.15 no.1
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• pp.51-74
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• 2015

The purpose of this exploratory research is to study Cashin's fashion philosophy and to draw her design characteristics through analysis of her work. As a result of this research, 76 garment pieces were selected from the 180 Bonnie Cashin collections at the University of Cincinnati to document and evaluate. The final selection includes: sixteen jackets, fifteen skirts, five pants, five tops, seven dresses, twenty five coats, and three capes. Bonnie Cashin specialized in practical and functional; yet innovative designs such as leather trimmed tweed Jackets/coats, canvas raincoats, suede leather coats, and ponchos. Her trademark elements include toggle closures, oversized pockets, her Noh coats, tweed suits, canvas raincoats, fringed suede dresses, funnel neck pullovers, jersey dresses, and ponchos. She emphasized function and comfort and she believed that a good design must also be practical. The examination of these 76 pieces from the University of Cincinnati's private Bonnie Cashin Collection brings to light Bonnie Cashin's creative design and what she represented in the development of American fashion design in the $20^{th}$ century.

• Journal of the Korea Convergence Society
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• v.9 no.11
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• pp.75-81
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• 2018

Anonymity and privacy issues are becoming important as all transactions in the blockchain are open to users. Public blockchains appear to guarantee anonymity by using public-key addresses on behalf of users, but they can weaken anonymity by tracking with various analytic techniques based on transaction graph. In this paper, we propose a scheme to protect anonymity and privacy by converging various security techniques such as k-anonymity, mixing, blind signature, multi-phase processing, random selection, and zero-knowledge proof techniques with incentive mechanism and contributor participation. Through performance analysis, our proposed scheme shows that it is difficult to invade privacy and anonymity through collusion attacks if the number of contributors is larger than that of conspirators.

• Animal Bioscience
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• v.37 no.10
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• pp.1683-1691
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• 2024

Objective: Yellow Korean native chicken (KNC-Y) is one of the five pure Korean indigenous chicken breeds that were restored through a government project in 1992. KNC-Y is recognized for its superior egg production performance compared to other KNC lines. In this study, we performed runs of homozygosity (ROH) analysis to discover selection signatures associated with egg production traits in the KNC-Y population. Methods: A total of 675 DNA samples from KNC-Y were genotyped to generate single nucleotide polymorphism (SNP) data using custom 60K Affymetrix SNP chips. ROH analysis was performed using PLINK software, with predefined parameters set for the analysis. The threshold of ROH island was defined as the top 1% frequency of SNPs withing the ROH among the population. Results: In the KNC-Y population, a total of 29,958 runs of homozygosity (ROH) fragments were identified. The average total length of ROH was 120.84 Mb, with each ROH fragment having an average length of 2.71 Mb. The calculated ROH-based inbreeding coefficient (F_ROH) was 0.13. Furthermore, we revealed the presence of ROH islands on chromosomes 1, 2, 4, 5, 7, 8, and 11. Within the identified regions, a total of 111 genes were annotated, and among them were genes related to economic traits, including PRMT3, ANO5, HDAC4, LSS, PLA2G4A, and PTGS2. Most of the overlapping quantitative trait locus regions with ROH islands were found to be associated with production traits. Conclusion: This study conducted a comprehensive analysis of ROH in the KNC-Y population. Notably, among the findings, the PTGS2 gene is believed to play a crucial role in influencing the laying performance of KNC-Y.

• Proceedings of the KSRS Conference
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• 2004.10a
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• pp.425-427
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• 2004

Motivation of this study is based on these two aspects: geologic uses of ASTER and application scheme of Spectral Mixture Analysis. This study aims at geologic mapping for mineral exploration using ASTER and LANDSAT 7 ETM+ at Mongolian plateau region by SMA. After basic pre-processing such as the normalization, geometric corrections and calibration of reflectance, related to endmembers selection and spectral signature deviation, both methods using spectral library and using PPI(Pixel Purity Index) are performed and compared on a given task. Based on these schemes, SMA is performed using LANDSAT 7 ETM+ and ASTER image. As the results, fraction map showing geologic rock types are enough to meet purposes such as geologic mapping and mineral potential mapping in the case of both uses of these different types of remotely sensed images. It concluded that this approach based on SMA with LANDSAT and ASTER is regarded as one of effective schemes for geologic remote sensing.