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Development of Anti-diabetes Drink Using with Silkworm(Bombyx mori L.) Extract (누에(Silkworm) 추출물을 이용한 기능성 항당뇨음료의 개발)

  • 최진호;김대익;박시향;백승진;김남주;류강선
    • Journal of Sericultural and Entomological Science
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    • v.45 no.2
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    • pp.96-102
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    • 2003
  • This study was designed to develope the functional anti-diabetes drink, Dia-D using silkworm (Bombyx mori L) extract Sprague-Dawley (SD) male rats (160${\pm}$10g) were fed basic diet (control group), and experimental diets (SWE-l0, 30, 60 groups and Daonil-40, 80 groups) added silkworm extract 10, 30 and 60mg/day or diabetes drug prepared and marketed by Handok Pham. Co., Daonil 40 and 80 mg/day for 12 days. Blood glucose contents were significantly decreased 25-30% in SWE-30 and SWE-60 groups, and about 35% in Daonil 40 and Daonil 80 groups compared with control group. Triglyceride (TG) and lipid peroxide (LPO) contents were significantly inhibited 10-16% and 8-13%, respectively, in SWE-30 and 60 groups, whereas these contents were 13-30% and 15%, respectively, in Daonil-40 and 80 groups compared with control group. Hydroxyl radical (OH) contents were significantly inhibited 19-20% in SWE-30 and 60 groups, and 7-12% in Daonil-40 and 80 groups compared with control group. Superoxide dismutase (SOD) activities were significantly increased 11-14% in SWE-30 and 60 groups, and 12-29% in Daonil-40 and 80 groups compared with control group. In results of clinical test using normal subjects, blood glucose content tested in NIAST subjects as anti-diabetes drink, Dia-D willi 100mg/vial was significantly decreased 17.5%, and these content tested in PKNU subjects as anti-diabetes drink, Dia-D with 150mg/vial was significantly decreased 20.5% compared with control group. These results suggest that administration of Dia-D as an anti-diabetes drink prepared with silkworm extract may playa very effective role in a decreasing of blood glucose in hyperglycemia patients.

Stress Day Index to Predict Soybean Yield Response by Subsurface Drainage in Poorly Drained Sloping Paddy Fields (배수불량 경사지 논에서 배수개선에 따른 콩의 수분스트레스 반응해석)

  • Jung, Ki-Yuol;Yun, Eul-Soo;Park, Chang-Young;Hwang, Jae-Bok;Choi, Young-Dae;Park, Ki-Do
    • Korean Journal of Soil Science and Fertilizer
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    • v.44 no.5
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    • pp.702-708
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    • 2011
  • There are considerable areas of wet paddy fields in Korea that requires improvement of its drainage system. In poorly drained sloping paddy fields, upland crops can be damaged by either rainfall or capillary rise of the water table caused by percolating water beneath the upper fields during summertime rainy season. The purpose of this study is to evaluate excess water stress of soybean yield by drainage systems. Four drainage methods namely open ditch, vinyl barrier, pipe drainage and tube bundle were installed within 1-m position at the lower edge of the upper paddy fields. Stress Day Index (SDI) approach was developed to quantify the the cumulative effect of stress imposed on a soybean yield throughout the growing season. SDI was determined from a stress day factor (SD) and a crop susceptibility factor (CS). The stress day factor is a measure degree and duration of stress of the ($SEW_{30}$). The crop susceptibility factor (CS) depends of a given excess water on crop stage. The results showed that SDI used to represent the moisture stress index was most low on the pipe drainage 64.75 compared with the open ditch 355.4, vinyl barrier 271.55 and tube bundle 171.55. Soybean grain yield increased continuously with the rate of 3% in Vinyl Barrier, 32% in Pipe Drainage and 16% in Tube Bundle.

Risk Factors of Socio-Demographic Variables to Depressive Symptoms and Suicidality in Elderly Who Live Alone at One Urban Region (일 도시지역의 독거노인에 있어서 우울증상 및 자살경향성에 영향을 미치는 인구학적 변인에 대한 고찰)

  • Park, Hoon-Sub;Oh, Hee-jin;Kwon, Min-Young;Kang, Min-Jeong;Eun, Tae-Kyung;Seo, Min-Cheol;Oh, Jong-Kil;Kim, Eui-Joong;Joo, Eun-Jeong;Bang, Soo-Young;Lee, Kyu Young
    • Korean Journal of Psychosomatic Medicine
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    • v.23 no.1
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    • pp.36-46
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    • 2015
  • Objectives: To understand the risk factors of demographic data in geriatric depression scale, and suicidality among in elderly who live alone at one urban region. Methods:In 2009, 589 elderly who live alone(age${\geq}$65) were carried out a survey about several socio-demographic data, Korean version of the Geriatric Depression Scale(SGDS-K) and Suicidal Ideation Questionnaire (SIQ). Statistical analysis was performed for the collected data. Results: Mean age of elderly who live alone is 75.69(SD 6.17). 40.1% of participants uneducated, 31.4% graduate from elementary school, 12.9% graduate from high school, 11.7% graduate from middle school, 3.2% graduate from university. Religionless, having past history of depression or physical diseases, low subjective satisfaction of family situation, and not having any social group activity have significance to depressive symptoms of elderly who live alone. Having past history of depression, religionless, low subjective satisfaction of family situation have significance to suicidality. Especially, low subjective satisfaction of family situation and having past history of depression are powerful demographic factor both depressive symptoms and suicidality of elderly who live alone. Conclusions: When we take care elderly who live alone, we should consider many things, but especially the social support network such as family satisfaction and past history of depression for reducing or preventing their depression and suicide both elderly depression and suicide who live alone.

Chemical components and hepato-protective effect of Lentinula edodes fermented by lactic acid bacteria (표고 유산균 발효물의 성분 및 간기능 보호 효과)

  • Im, Seung-Bin;Kim, Kyung-Je;Jin, Seong-Woo;Koh, Young-Woo;Ha, Neul-I;Jeong, Hee-Gyeong;Lee, Jae-Keun;Yun, Kyeong-Won;Seo, Kyoung-Sun
    • Journal of Mushroom
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    • v.19 no.3
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    • pp.191-199
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    • 2021
  • This study was conducted to improve the useful components and biological activity of Lentinula edodes fermented by lactic acid bacteria (LAB). Three LAB strains (Lactobacillus brevis KCCM 11904, L. plantarum KCCM 354469, and L. fermentum KCCM 12116) were inoculated and used for L. edodes hot water extract (10%, 20%, 30%) fermentation. LAB fermentation of L. edodes hot water extracts decreased pH and thus were more acidic than non-fermented L. edodes hot water extract. β-glucan and ergothioneine contents were increased by L. edodes in a concentration-dependent manner. The ergothioneine and β-glucan contents were highest in fermented with 30% L. edodes hot water extract fermented by L. plantarum and L. brevis (40.48 mg/100 g and 13.94%, respectively). The hepato-protective effect of fermented L. edodes hot water extracts by the three LAB were tested using Sprague-Dawley rat primary hepatocytes. In primary hepatocytes obtained following liver injury induced by acetaminophen, fermented L. edodes hot water extracts by the three LAB showed protective effects, as evident by reduction of the aspartate aminotransferase, alanine aminotransferase, and lactate dehydrogenase liver markers. The collective results indicate that the fermented L. edodes hot water extracts obtained using LAB are potentially valuable in preventing or treating liver disease.

Study on the Home-range and Winter Habitat Pintail using the Wild-Tracker (WT-300) in Korea (WT-300을 이용한 월동기 고방오리(Anas acuta)의 행동권 및 서식지 이용연구)

  • Jung, Sang-Min;Shin, Man-Seok;Cho, Hae-jin;Han, Seung-Woo;Son, Han-Mo;Kim, Jeong Won;Kang, Sung-Il;Lee, Han-soo;Oh, Hong-Shik
    • Korean Journal of Environment and Ecology
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    • v.33 no.1
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    • pp.1-8
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    • 2019
  • Pintail (Anas acuta) is the major wintering bird in South Korea and known as a major mediator of the highly pathogenic avian influenza (HPAI). Pintail migrates long distances between Russian Siberia and Korea. This species prefers a rice paddy area as their winter habitat. The purpose of this study is to provide the data necessary for the conservation and management of bird habitats in Korea by understanding the wintering home-range and habitat of pintail in Korea. We captured six pintails using a cannon-net in the winter of 2015 and attached the GPS-mobile phone based telemetry (WT-300) on them to study the wintering home-range and wintering habitat. We analyzed the tracking location data using ArcGIS 9.0 Animal Movement Extension and calculated Kernel Density Estimation (KDE) and Minimum Convex Polygon (MCP). The average home-range in the wintering ground analyzed by MCP was $677.3km^2$ (SD=130.2, n=6) while the maximum and minimum were $847.7km^2$ and $467.5km^2$, respectively. Extents of home-range analyzed by KDE were $194.7km^2$ (KDE 90%), $77.4km^2$ (KDE 70%), and $35.3km^2$ (KDE 50%). The pintails mostly used both sea and paddy field as habitat in the winter season and utilized paddy fields more during the nighttime and than the daytime. We concluded that the home-range and habitat of pintails in the winter could be used as the reference data for the preservation of species, management of habitats, and coping with a breakout of HPAI.

The Radioprotection Effect of Protaetia Brevitarsis Larvae Extracts on the Reproductive in Female Rats Irradiated Gamma Ray (감마선에 조사된 암컷 흰쥐의 생식기관에 대한 흰점박이꽃무지 유충 추출물의 방사선 방호효과)

  • Jeong, Geun-Woo;Joung, Do-Young;Kim, Chang-Ju;Lee, Ji-Eun;Jeong, Sang-Hyun;Kim, Hee-Jin;Min, Byung-In
    • Journal of the Korean Society of Radiology
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    • v.15 no.2
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    • pp.247-255
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    • 2021
  • The purpose of this study was to examine the radiation protection effect of protaetia brevitarsis larvae extracts known as antioxidant food. In this study 90 female rats were clssified in to 5 groups: NC Group, PBE Group, IR Group, PBE+IR Group and IR+PBE Group. In IR Group, 7 Gy of Co-60 gamma ray was irradiated to SD rat and protaetia brevitarsis larvae extracts were administered orally at 200 mg/kg once a day for 14 days. And then on the 1 day, 7 days, 21 days later after irradiation, changes in blood cell component, superoxide dismutase(SOD) activity, spleen index, histopathological evaluation of the ovary and uterus were observed. As a result, the PBE+IR Group (p<0.01, p<0.05) and IR+PBE Group (p<0.01, p<0.01) showed a significantly radiation protection than the IR Group in lymphocyte and red blood cell on the 21 days. It was also confirmed that SOD activity of PBE+IR Group (p<0.01) and IR+PBE Group (p<0.01) was significantly increased than the IR Group. In spleen index, PBE+IR Group (p<0.05) and IR+PBE Group (p<0.01) showed a significantly recovery than the IR Group. In histopathological observation, PBE+IR Group in the ovary and PBE+IR, IR+PBE Group in the uterus showed less inflammatory reactions of cystoplasm than the IR Group. Based on These results, It is judged that protaetia brevitarsis larvae Extracts have radiation protection effect against blood and reproductive. It is expected to be useful for research of radiation protection agent.

A Survey on the Visual Characteristics and Preference of Road Landscape of Traditional Gardens in Suzhou, China based on Rockery Ratio - With a Comparison of Consciousness between Korean and Chinese - (중국 전통원림의 치석피도(置石被度)에 따른 원로경관의 시지각적 특성 분석 - 한국인과 중국인 시지각 비교를 중심으로 -)

  • Kim, Dong-Chan;Park, Yool-Jin;Song, Mei-Jie
    • Journal of the Korean Institute of Traditional Landscape Architecture
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    • v.29 no.4
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    • pp.70-77
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    • 2011
  • This study takes road landscape of traditional Chinese Kangnam gardens in Suzhou as the object. It compares the relations and differences between preferences of Korean and Chinese on road landscapes with different rockery ratios, and studies the differences between Korean and Chinese's adjective visual characteristics of road landscape of traditional gardens and impacts of visual characteristics on preference. The following is the research process: Firstly, the theoretical survey of road landscape of traditional Chinese Kangnam gardens is conducted, pictures of the road landscape of gardens in Suzhou are taken, and 15 pictures are selected based on rockery ratio. Secondly, in order to grasp the visual preference and landscape characteristics of road landscape of garden in Suzhou, 15 pictures and 21 pairs of adjectives are adopted for the questionnaire survey. Thirdly, in order to grasp the differences between preferences of Korean and Chinese on road landscape of traditional Chinese Kangnam gardens, thet-test analysis is conducted. In order to grasp the impacts of rockery ratio on preference, and after the classification of landscape pictures based on rockery occupancy, the average analysis, factor analysis of results of questionnaire survey for Korean and Chinese are conducted respectively. In order to grasp the differences of incentives of landscape preference, the incentive analysis of results of questionnaire survey for Korean and Chinese is carried out. In order to grasp the impacts of various factors on the preference, The results are as follows: The results of analysis of differences between Korean and Chinese's preference on road landscape of traditional Chinese Kangnam gardens show that the overall preference of Chinese is higher than that of Korean. The results of the landscape preference analysis show that the ranking order of average value of Korean and Chinese's preference on rockery ratio categories is: medium ratio, very small ratio, small ratio, large ratio, very large ratio. The results of analysis of relations between rockery ratio of traditional Chinese Kangnam gardens and preference show that the preference increases as the rockery ratio decreases, and the rockery ratio variation causes greater impacts on Korean. Results of the analysis of visual characteristics, factors of visual characteristics of Koreans are "aesthetic factor", "comfort factor", "neat(orderly) factor", and "fun factor". The visual characteristics of Chinese has three factors, namely "psychological factor", "comfort factor", and "neat factor".

Effect of Final Irrigation Timing before Simulated Dark Shipping on Post-shipping Performance of Potted Phalaenopsis Sogo Yukidian 'V3' (팔레놉시스 분화의 모의수송 전 최종 관수 시기가 수송 후 생육에 미치는 영향)

  • Jeong, Ju Hui;Jeon, Jeong Bin;Kim, Sang Yoon;Oh, Wook
    • Journal of Bio-Environment Control
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    • v.30 no.1
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    • pp.65-71
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    • 2021
  • This study was carried out to investigate the effect of the final irrigation timing (FIT) before packaging for long-term transportation on growth, flowering, and crop quality of Phalaenopsis after simulated dark shipping (SDS). Phalaenopsis Sogo Yukidian 'V3' plants grown in 11 cm-diameter plastic pots filled with potting media (sphagnum moss + bark or only sphagnum moss) were packaged in paper boxes for export at 3.5, 7, 10 days (FIT 3.5, 7,10; Experiment 1) and 4, 6, 8, 10 days (FIT 4, 6, 8, 10; Experiment 2) after the final irrigation and then stored in a growth chamber at 20 ± 1℃ and 70 ± 3% RH created for SDS. After 4 weeks, the plants were taken out and grown in a greenhouse at 23 ± 3℃ and 70 ± 5% RH, and crop characteristics were measured during cultivation. In Experiment 1, the survival rate of FIT 3.5 plants was lower than that of FIT 7 and FIT 10. There was no difference between treatments in days to first flower, the number of florets, and the elongation rate of flower stalks. In Experiment 2, the percentage of rotted leaves was lowest in FIT 6 when before forcing and at 12 weeks after forcing, and that of FIT 8 was similar to FIT 6 when before forcing, but slightly increased after 12 weeks. The percentage of rotted leaves of FIT 10 was highest and that of FIT 4 was also high. There was little difference in flowering characteristics among treatments. In conclusion, the FIT before packaging for long-term (4 weeks) transportation of potted Phalaenopsis 'V3' affected the leaf rot rather than the post-shipping growth and flowering. And it was considered appropriate to set the volumetric water content of the potting media just before packaging to about 30%.

Radiation Protection Effect of Blueberries in the Hematopoietic Cells of White Rats (흰쥐의 조혈세포에서 블루베리의 방사선 방호효과)

  • Lee, Jun-Haeng
    • Journal of the Korean Society of Radiology
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    • v.16 no.3
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    • pp.335-341
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    • 2022
  • The purpose of this study was to investigate the radiation protection effect of blueberries. The experimental animals used in this study were 8-week-old 21 SD male rats weighed 280-300 g. The animals were set to a normal group (A), a 5 Gy control group (B), and a 5 Gy experimental group (C) of seven rats each, and (50 mg/kg/day) of physiological saline solution of blueberries were orally administered twice a day with an oral dose of (200 mg/kg/day) for seven days and 5 Gy of radiation was irradiated in the case of groups B and C. As a result, it was identified that there was significance in white blood cells in this study (p<0.000). There was no significant difference in red blood cells or platelets. When examined in detail, among white blood cells (WBC), neutrocytes were found to be significantly different among the three groups: normal, control, and experimental groups (p<0.004). Lymphocytes were also found to be statistically significantly different among the three groups (p<0.000). Monocytes were not found to be statistically significantly different (p<0.483). When red blood cells (RBC) were examined, hemoglobin (HGB) was not found to be statistically significant different among the three groups (p<0.291). Hematocrit (HCT) was not found to be statistically significantly different among the three groups, either (p<0.564). Mean corpuscular volume (MCV) was found to be statistically significantly different among the three groups (p<0.001). Mean corpuscular hemoglobin (MCH) was also found to be statistically significantly among the three groups (p<0.028). Mean corpuscular hemoglobin concentration (MCHC) was found to be statistically significantly different among the three groups(p<0.020). Red blood cell distribution width (RDW) was not found to be statistically significantly different among the three groups (p<0.09). When platelets (PLT) were examined in detail, mean platelet volume (MpV) was found to be statistically significantly different among the three groups (MpV) (p<0.04). In conclusion, based on this study, blueberries are considered to have radiation protection effects.

The Radioprotection Effect of Dioscorea Quinqueloba Extracts on the Prostate and Heart in Male Rats (수컷 쥐 전립선과 심장에 대한 단풍마 추출물의 방사선 방호효과 연구)

  • Jae-Gyeong, Choi;Chang-Ju, Kim;Geun-Woo, Jeong;Sang-Hyun, Jeong;Sung-Hyun, Joo;Byung-In, Min
    • Journal of the Korean Society of Radiology
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    • v.16 no.6
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    • pp.779-786
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    • 2022
  • This study is designed to examine the effects of Dioscorea Quinqueloba extract as a natural radiation protection agent on the prostate and heart of male rats. Dioscorea Quinqueloba extract is well known to prevent the male-specific disease and heart disease. In this study, the Gamma-ray 10 Gy was irradiated in whole body of male rat to identify radioprotective effect by Dioscorea Quinqueloba extract. After irradiation, tissue change, SOD (Superoxide Dismutase) activity changes and hematological changes were observed. DQ+IR group showed higher lymphocyte, white blood cell, platelet levels than the IR group. In the NC and DQ groups, the number of prostate gland cells and the gap between cells were relatively narrow. But in the IR group, the cells died significantly and the gap widened. In the DQ+IR group, the gap between cells increased similarly to the IR group, but the number of dead cells was noticeably smaller. In the NC and DQ groups, the cardiovascular and myocardium are clearly separated, and cell nuclei are in good condition. But in the IR group, the cardiovascular and myocardium boundaries were disrupted, and the number of dead cell nuclei was high. In the DQ+IR group, although the boundaries were widened, but not disrupted and the number of dead cell nuclei was high. Therefore, Dioscorea Quinqueloba extract is judged to have radioprotective properties for the prostate and cardiovascular.