• Title/Summary/Keyword: Screening Methodology

Search Result 149, Processing Time 0.027 seconds

Research Ethics within an Internet-based Research Setting: Current Literature Investigation

  • Eungoo KANG;Hee-Joong HWANG
    • Journal of Research and Publication Ethics
    • /
    • v.5 no.2
    • /
    • pp.17-23
    • /
    • 2024
  • Purpose: The internet, as a tool, avenue, and field, has wide-researching and specific ethical concerns. Internet-based research ethics is a field that spreads across numerous fields, scoping from natural and biomedical sciences to social sciences, and arts and humanities. Thus, this study which investigates research ethics within an Internet-based Research Setting will be quite valuable. Research design, data and methodology: The current authors widely took a look at prior and present literature dataset to explore research ethics within an Internet-based setting. Using numerous search engine, such as 'Goole Scholar', 'Scopus', and 'Web of Science', the current authors could obtain total 42 prior studies that are relevant with our research topic. Results: Based on the screening process in the literature datasets, this study could categorize four areas of the research ethics within Internet-based research setting as follows: (1) Human Subjects Ethics, (2) Big Data Ethical Issues, (3) Research Ethics and Cloud, and (4) Computing Interviews and Surveys Ethics. Conclusions: This study concludes that although internet-based research has many benefits, the accompanying ethical issues are many. The lack of uniformity in the concept and terminology of online research methods typically brings forth confusion and makes it hard for new researchers to develop mutual guidelines.

Effects of Unified Theory of Acceptance and Use of Technology (UTAUT) Within the Circumstance of Fourth Industrial Setting

  • Soo-Hwa LEE;Eungoo KANG
    • Fourth Industrial Review
    • /
    • v.4 no.2
    • /
    • pp.11-18
    • /
    • 2024
  • Purpose: This research delves into the topic by exploring the impacts of the Unified Theory of Acceptance and Use of Technology (UTAUT) on the fourth industrial setting. As the study begins with a comprehensive review of the literature to find other scholars' contributions, the present authors try to synthesize and integrate scattered related topics in the literature dataset. Research design, data and methodology: We used a descriptive, causal, and explanatory research design hybrid. A causal research design is an approach used to investigate the interaction and relationship between given variables. The screening began with searching using keywords, filtering using the inclusion criteria, and arriving at the final set of sources. Results: There were four crucial findings: 1. The Performance Expectancy Construct Has Strongly Influenced and Influenced the Decision to Acquire and Use a Given Technology. 2. Effort Expectancy Construct Has Influenced the Trends of Adopting. 3. Social Influence and Impact on Choice and Use of Technologies. 4. Facilitating Conditions as A Factor in Modern Production and Consumption. Conclusions: All in all, UTAUT is used in a predictive manner and very instrumental for the producers and users of various technologies. Four primary constructs are critical in making the theory complete, essential, and reliable within the fourth industrial setting.

Identification of characterization and statistical optimization of medium constituent for Bacillus subtilis SCJ4 isolated from Korean traditional fermented food (전통 장류 유래 Bacillus subtilis SCJ4의 특성확인 및 통계학적 방법을 이용한 배양조건 최적화)

  • Jeong, Su-Ji;Yang, Hee-Jong;Jeong, Seong-Yeop;Jeong, Do-Youn
    • Korean Journal of Microbiology
    • /
    • v.51 no.1
    • /
    • pp.48-60
    • /
    • 2015
  • 612 strains isolated from Korean traditional fermented food in Sunchang and their investigated biochemical characterization and ability of biogenic amines non-producing. We selected the SCJ4 having various activity by measurement of extracellular enzyme, antioxidant and antimicrobial activities. Selected strain SCJ4 by 16S rRNA sequencing and biochemical characterization was named Bacillus subtilis SCJ4. And then, we investigated cell growth of SCJ4, and optimized of culture medium constituents using response surface methodology as statistically method. Response surface methodology used Plackett-Burman experimental design for screening of medium constituent. Tryptone, peptone and $MgSO_4$ as medium constituent improving cell growth selected. In order to find out optimal concentration on each constituent, we carried out central composite design. Consequently, optimized concentrations of tryptone, peptone and $MgSO_4$ were predicted to be 15.35 g/L, 12.235 g/L, and 3.5 g/L respectively. Through the model verification, we confirmed about 1.28-fold improvement of the dried cell weight from 0.8767 g/L to 1.1222 g/L when compared to basal medium.

Optimization of Medium for Astaxanthin Production by Paracoccus sp. Using Response Surface Methodology (반응표면분석 법을 이용한 Paracoccus sp.의 Astaxanthin 생산배지 최적화)

  • Choi, Jong-Il;Lee, Hee-Sub;Choi, Seon-Kang;Kim, Jae-Hun;Kim, Jin-Kyu;Misawa, Norihiko;Byun, Myung-Woo;Lee, Ju-Woon
    • KSBB Journal
    • /
    • v.24 no.3
    • /
    • pp.321-326
    • /
    • 2009
  • This study was to optimize the medium components for astaxanthin production in Paracoccus sp. through surface response methodology. A screening test was first conducted on 5 medium components using a Plackett-Burman design, from which $MgSO_4$ and yeast extract were identified as the significant factors affecting astaxanthin production. These significant factors were optimized by central composite design of experiments and response surface methodology, as 2.83 g/L $MgSO_4$ and 7.02 g/L yeast extract, respectively. The expected astaxanthin concentration with these optimized medium compositions were 0.925 mg/L. In flask culture, the experimentally obtained concentration of astaxantin was 1.021 mg/L, where it had been 0.4 mg/L before optimization.

Screening of Biogenic Amine Non-Producing Yeast and Optimization of Culture Conditions Using Statistical Method for Manufacturing Black Raspberry Wine (복분자 와인 제조를 위한 바이오제닉 아민 비생성 효모의 선별 및 통계학적 기법을 이용한 배양조건 최적화)

  • Yang, Hee-Jong;Jeong, Su-Ji;Jeong, Seong-Yeop;Heo, Ju-Hee;Jeong, Do-Youn
    • Journal of the Korean Society of Food Science and Nutrition
    • /
    • v.44 no.4
    • /
    • pp.592-601
    • /
    • 2015
  • Rubus coreanus is known as Korean black raspberry, native to Korea, Japan, and China. Preliminary studies evaluating their potential for cancer treatment in mammalian test systems are ongoing. In recent years, interest has been renewed due to their high levels of anthocyanins. Anthocyanins in black raspberry are important due to their potential health benefits as dietary antioxidant, anti-inflammatory compound, and as a chemopreventive agent. In the present study, Saccharomyces cerevisiae BA29 was isolated from black raspberry fruit and fruit juice as a biogenic amine non-producing strain for manufacturing of black raspberry wine, after which we investigated its characteristics: biogenic amine-producing ability, cell growth ability, alcohol-fermentation ability, and resistance to alcohol, glucose, and sulfur dioxide. Based on preliminary experiments, we optimized culture medium compositions for improving dried cell weight of S. cerevisiae BA29 by response surface methodology (RSM) as a statistical method. Design for RSM used a central composite design, and molasses with the industrial applicability was used as a carbon source. Through statistical analysis, we obtained optimum values as follows: molasses 200 g/L, peptone 30 g/L, and yeast extract 40 g/L. For the model verification, we confirmed about 3-fold improvement of dried cell weight from 6.39 to 20.9167 g/L compared to basal yeast peptone dextrose medium. Finally, we manufactured black raspberry wine using S. cerevisiae BA29 and produced alcohol of 20.33%. In conclusion, S. cerevisiae isolated from black raspberry fruit and juices has a great potential in the fermentation of black raspberry wine.

Impact Assessment of Sea_Level Rise based on Coastal Vulnerability Index (연안 취약성 지수를 활용한 해수면 상승 영향평가 방안 연구)

  • Lee, Haemi;Kang, Tae soon;Cho, Kwangwoo
    • Journal of Korean Society of Coastal and Ocean Engineers
    • /
    • v.27 no.5
    • /
    • pp.304-314
    • /
    • 2015
  • We have reviewed the current status of coastal vulnerability index(CVI) to be guided into an appropriate CVI development for Korean coast and applied a methodology into the east coast of Korea to quantify coastal vulnerability by future sea_level rise. The CVIs reviewed includes USGS CVI, sea_level rise CVI, compound CVI, and multi scale CVI. The USGS CVI, expressed into the external forcing of sea_level rise, wave and tide, and adaptive capacity of morphology, erosion and slope, is adopted here for CVI quantification. The range of CVI is 1.826~22.361 with a mean of 7.085 for present condition and increases into 2.887~30.619 with a mean of 12.361 for the year of 2100(1 m sea_level rise). The index "VERY HIGH" is currently 8.57% of the coast and occupies 35.56% in 2100. The pattern of CVI change by sea_level rise is different to different local areas, and Gangneung, Yangyang and Goseong show the highest increase. The land use pattern in the "VERY HIGH" index is dominated by both human system of housing complex, road, cropland, etc, and natural system of sand, wetland, forestry, etc., which suggests existing land utilization should be reframed in the era of climate change. Though CVI approach is highly efficient to deal with a large set of climate scenarios entailed in climate impact assessment due to uncertainties, we also propose three_level assessment for the application of CVI methodology in the site specific adaptation such as first screening assessment by CVI, second scoping assessment by impact model, and final risk quantification with the result of impact model.

The Study for Incidence Trends of Colorectal Cancer in Jeju-do (제주도 대장암 발생률 추세에 대한 연구)

  • Chang, Weon-Young
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.17 no.5
    • /
    • pp.566-573
    • /
    • 2016
  • The age-adjusted incidence rate (AAR) of colorectal cancer in Korea peaked in 2011 and then began to decline. However, the AAR of colorectal cancer in Jeju increased continually from 1999 to 2013. Compared with the 16 major cities in Korea, the inhabitants of Jeju-do have a low cancer screening program participation rate, high alcohol consumption rate and high BMI. The present study aimed to provide a statistical basis for the lowering of the incidence of colorectal cancer in Jeju-do. The Jeju regional cancer institute data from 1999 to 2013 was used to analyze the between Jeju-do and Korea using the Joinpoint Regression program (Statistical Methodology and Applications Branch, Surveillance Research Program, National Cancer Institute) Version 4.2.0 - April 2015. The AAR of colorectal cancer in Jeju-do has being increasing because of the increase in the rates of male colon cancer (average annual percent change 8.422%, p-value<0.000), female colon cancer (AAPC 6.136%, p-value<0.000), male rectal cancer (AAPC 4.221%, p-value 0.003) and colon cancer in people aged over 50 years (AAPC 7.986% p-value<0.000). The results of this study suggest that the treatment of precancerous lesions of the male rectum and lowering of the incidence of colon cancer in people aged over 50 years are necessary to reduce the colorectal cancer incidence rate in Jeju-do.

A Study of Ending Credit in Animations-Focused on Credit Cookie (극장판 애니메이션의 엔딩 크레딧 양상연구: 쿠키 영상을 중심으로)

  • Park, Sung-Won;Lee, Hye-won
    • Journal of Information Technology Applications and Management
    • /
    • v.27 no.1
    • /
    • pp.187-198
    • /
    • 2020
  • With the development of technology and the creation of an entertainment environment for leisure, various marketing strategies are being used in the film industry. Among them, the use of the credit cookie of ending credits was very effective in producing the series. The ending credit is the time it takes to show the names of the people who made the movie, which is meaningless to the audience. There is a cost to produce a ending credit but It wasn't made because no revenue was generated. The credit cookie was inserted into this ending credit area, which brought new pleasure to the audience. Most of them were epilogue images showing the story behind the movie, NG images showing the NG situation during film production, and In videos mentioned in the movie but not shown in the movie itself. As various ideas about credit cookie were connected with marketing, a series movie and a spin-off foretelling the derivative works after the screening work were produced and have a new meaning. As a result, the time of ending credits, which had no commercial value, became the methodology of the most powerful promotional strategy. Looking at the difference between live-action film and animation in producing such credit cookie, unlike live-action films that edit the remaining parts after shooting, the NG video of the animation has a lot of time and money to produce. So, it hasn't try very well, and it seems to have been actively produced when moving from 2D animation to 3D animation. This is because 3D animation, which has already been modeled, can create new NG scenes by simply adding animating based on the layout of the created scene. Since it is possible to produce an episode movie at a low cost and time, and to use the scenes of the movie after the production, it will be necessary to strategically produce credit cookie for promotion in animation.

Analysis on the Risk-Based Screening Levels Determined by Various Risk Assessment Tools (III): Proposed Methodology for Lead Risk Assessment in Korea (다양한 위해성평가 방법에 따라 도출한 토양오염 판정기준의 차이에 관한 연구(III): 우리나라 납 오염 위해성평가 방법 제안)

  • Jung, Jae-Woong;Nam, Kyoungphile
    • Journal of Soil and Groundwater Environment
    • /
    • v.20 no.6
    • /
    • pp.1-7
    • /
    • 2015
  • The most critical health effect of lead exposure is the neurodevelopmental effect to children caused by the increased blood lead level. Therefore, the endpoint of the risk assessment for lead-contaminated sites should be set at the blood lead level of children. In foreign countries, the risk assessment for lead-contaminated sites is conducted by estimating the increased blood lead level of children via oral intake and/or inhalation (United States Environmental Protection Agency, USEPA), or by comparing the estimated oral dose to the threshold oral dose of lead, which is derived from the permissible blood lead level of children (Dutch National Institute for Public Health and the Environment, RIVM). For the risk assessment, USEPA employs Integrated-Exposure-Uptake-Biokinetic (IEUBK) Model to check whether the estimated portion of children whose blood lead level exceeds 10 µg/dL, threshold blood lead level determined by USEPA, is higher than 5%, while Dutch RIVM compares the estimated oral dose of lead to the threshold oral dose (2.8 µg/kg-day), which is derived from the permissible blood lead level of children. In Korea, like The Netherlands, risk assessment for lead-contaminated sites is conducted by comparing the estimated oral dose to the threshold oral dose; however, because the threshold oral dose listed in Korean risk assessment guidance is an unidentified value, it is recommended to revise the existing threshold oral dose described in Korean risk assessment guidance. And, if significant lead exposure via inhalation is suspected, it is useful to employ IEUBK Model to derive the risk posed via multimedia exposure (i.e., both oral ingestion and inhalation).

Evaluation of the Manual Method of Liquid-Based Uterine Cervicovaginal Cytology - By The Manual Method Based on $SurePath^{TM}$ Methodology (자궁경부 액상세포검사의 수기 검사법에 대한 고찰 - $SurePath^{TM}$ 검사법을 준용한 수기 검사법으로 -)

  • Park, Jong-Myoung;Jang, Jin-Wook;Lim, So-Yeo;Suh, In-Soo;Lee, Jong-Gi
    • The Korean Journal of Cytopathology
    • /
    • v.15 no.2
    • /
    • pp.86-91
    • /
    • 2004
  • Liquid-Based Uterine Cervicovaginal Cytology is known to be a sensitive and effective screening method for cervical neoplasm $MonoPrep^{TM},\;ThinPrep^{TM},\;and\;SurePath^{TM}$ methods have been recently used as Liquid-Based Uterine Cervicovaginal Cytology techniques, and the $SurePath^{TM}$ method has been used in Sung-Yoon Reference Laboratory since 2003. The goal of Liquid-Based Uterine Cervicovaginal Cytology is to separate cervical epithelial cells from non-target cells, red blood cells and neutrophils. This report describes a study which evaluated cellularity, stainablilty, and cellular changes of epithelial cels in samples processed using a manual technique as compared to samples processed using $SurePath^{TM}$ automated method. The samples processed by means of a manual technique contained a cellularity of epithelial cells similar to that of the samples processed using the $SurePath^{TM}$ automated method. In addition, we compared variable density gradient reagents, including dextran, dextrose, and sucrose, to $SurePath^{TM}$ gradient media in order to evaluate cell fractionation and cellularity of epithelial cells. 10% dextran of gradient media shows good fractionation. The samples processed with 10% dextran demonstrated sufficient cellularity of epithelial cells and shows the fewest cellular changes. In conclusion, using a manual technique on these samples is easier to read than those results obtained using the $SurePath^{TM}$ automated method.