• Food Science and Biotechnology
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• v.16 no.6
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• pp.1035-1040
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• 2007

Epidemiologic studies have shown important relationships between oxidative stress and Alzheimer's disease (AD) brain. In this study, free radical scavenging activity and neuronal cell protection effect of aqueous methanol extracts of Acanthopanax senticosus (A. senticosus) were examined. $H_2O_2$-induced oxidative stress was measured using 2',7'-dichlorofluorescein diacetate (DCF-DA) assay. Pretreatment with the phenolics of A. senticosus prevented oxidative injury against $H_2O_2$ toxicity. Since oxidative stress is known to increase neuronal cell membrane breakdown, leading to cell death, lactic dehydrogenase release, and trypan blue exclusion assays were utilized. We found that phenolics of A. senticosus have neuronal cell protection effects. It suggests that the phenolics of A. senticosus inhibited $H_2O_2$-induced oxidative stress and A. senticosus may be beneficial against the oxidative stress-induced risk in AD.

• Journal of the Korean Society of School Health
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• v.24 no.2
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• pp.190-198
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• 2011

Purpose: The purpose of this study was to compare stress levels of middle school students by grade. Methods: This was a descriptive comparative survey using as convenience sample of 701 1st, 2nd and 3rd-grade students. The stress levels was measured by stress scale that consisted of 65 items regarding personal characters family, school, and peer factors. The data were analyzed by ${\chi}^2$-test, t-test, ANOVA, and multiple regression using the SPSS/WIN 12.0 statistical program. Results: 1st graders and female students showed higher stress levels than 2nd, 3rd graders and male students, respectively. Conclusion: Grade, gender, life satisfaction, and regional levels were all significant factors associated with high stress levels among middle school students. Development of stress management program for this specific population, especially targeting students who are 1st Grader and living in rural areas, is needed.

• Journal of Welding and Joining
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• v.29 no.2
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• pp.46-55
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• 2011

This paper deals with the crack propagation life assessment of T-joint welded structure where typical fatigue cracks have been frequently initiated when the marine vessels experience the storm load. Welding residual stresses are calculated to investigate its effects on the fatigue life. Thereafter the residual stress distribution was applied to the AFGROW life prediction program, which incorporated the loading, the welding residual stress, and the geometric shape of the structure. The fatigue tests of the T-joint welded specimen under storm loading show the beach mark clearly generated on the fractured section of the weldment. The crack propagation life estimated based on the beach mark is compared with that of AFGROW to validate the life prediction. Based on the results, the evaluation method of the remaining fatigue life for T-joint fillet weldment of marine vessel's cargo hold with random load or storm load was established.

• 한국생물공학회:학술대회논문집
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• 2005.04a
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• pp.540-540
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• 2005

• Molecules and Cells
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• v.19 no.2
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• pp.228-231
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• 2005

Recent characterization of several genes involved in plant defense responses suggested that ubiquitin-mediated protein degradation has a role in these responses. We isolated two cDNAs (NtUBA1 and NtUBA2) encoding ubiquitin-activating enzyme (E1) from Nicotiana tabacum cv. BY-2. The open reading frames of both encoded 1080 amino acids, corresponding to molecular masses of 120 kDa. The E1s and corresponding transcripts were upregulated by infection with tobacco mosaic virus (TMV) and tomato mosaic virus (ToMV), and to a lesser extent by cucumber mosaic virus (CMV). Furthermore, they were also upregulated by wounding stress, and the plant hormones salicylic acid, jasmonic acid and the ethylene precursor, aminocyclopropane-1-carboxylic acid (ACC). Our findings support the idea that the ubiquitin-proteasome system plays a role in plant disease defenses.

• Nuclear Engineering and Technology
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• v.53 no.12
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• pp.4166-4178
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• 2021

The Control Rod Drive Mechanism (CRDM) is an essential part of the reactor, which realizes the start-stop and power adjustment of the reactor by lifting and lowering the control rod assembly. As a moving part in CRDM, the latch directly contacts with the control rod assembly, and the life of latch is closely related to the service life of the reactor. In this paper, the relationship between the life of the latch and the step stress, friction stress, and impact stress in the process of movement is analyzed, and the optimization methodology and process of latch life based on the approximate model are proposed. The design variables that affect the life of the latch are studied through the experimental design, and the optimization objective of design variables based on the latch life is established. Based on this, an approximate model of the life of the latch is built, and the multi-objective optimization of the life of the latch is optimized through the NSGA-II algorithm.

• Tribology and Lubricants
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• v.29 no.1
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• pp.33-38
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• 2013

This study is aimed to predict the fatigue life for pitch bearings under combined radial, thrust load and moment. In order to do this, a series of simulation such as bearing load distribution, initial surface stress, subsurface stress and fatigue analysis is needd. Fatigue life for pitch bearing can be predicted by using a bearing's material fatigue property.

• Molecules and Cells
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• v.27 no.5
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• pp.609-613
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• 2009

It has been reported that selenoprotein W (SelW) mRNA is highly expressed in the developing central nerve system of rats, and its expression is maintained until the early postnatal stage. We here found that SelW protein significantly increased in mouse brains of postnatal day 8 and 20 relative to embryonic day 15. This was accompanied by increased expression of SOD1 and SOD2. When the expression of SelW in primary cultured cells derived from embryonic cerebral cortex was knocked down with small interfering RNAs (siRNAs), SelW siRNA-transfected neuronal cells were more sensitive to the oxidative stress induced by treatment of $H_2O_2$ than control cells. TUNEL assays revealed that $H_2O_2$-induced apoptotic cell death occurred at a higher frequency in the siRNA-transfected cells than in the control cells. Taken together, our findings suggest that SelW plays an important role in protection of neurons from oxidative stress during neuronal development.

• Tribology and Lubricants
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• v.22 no.6
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• pp.320-328
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• 2006

In this study, the simulation of rolling contact fatigue based on stress analysis is conducted under Elastohydrodynamic Lubrication state. To predict a crack initiation life accurately, it is necessary to calculate contact stress and subsurface stresses accurately. Contact stresses are obtained by contact analysis of a semi-infinile solid based on the use of influence functions and the subsurface stress field is obtained using rectangular patch solutions. And a numerical algorithm using Newton-Rapson method was constructed to calculate the Elastohydrodynamic lubrication pressure. Based on these stress values, several multiaxial high-cycle fatigue criteria are used and the critical loads corresponding to fatigue limits are calculated.

• Journal of the Korean Dietetic Association
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• v.27 no.2
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• pp.113-123
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• 2021

This study aimed to examine the association between sleep duration, stress levels, and dietary behavior in adolescents. A survey was conducted on 453 students (227 male, 226 female) in high schools in the Chungbuk area. The participants were divided into groups based on daily sleep duration: group I (<5 hrs/d), group II (≥5 hrs/d and <6 hrs/d), group III (≥6 hrs/d and <7 hrs/d), and group IV (≥7 hrs/d). To measure the stress levels of participants, the survey had questions covering a variety of areas, including school life, family life, social relationships, and personal evaluation. To assess the dietary behaviors of participants, the survey included questions encompassing the Nutrition Quotient for Korean adolescents (NQ-A). Among female students, the sleep duration group IV had significantly lower total stress (P=0.022) and significantly lower stress in the personal evaluation area than the sleep duration group I (P=0.004). In the analysis of NQ-A, among female students, the sleep duration group IV showed significantly higher scores in balance (P=0.004), diversity (P=0.016), and total NQ-A score area (P=0.007) compared to other groups. There was a significant negative correlation between sleep duration and stress scores in total students (r=-0.24, P<0.001), while a significant positive correlation was seen between sleep duration and NQ-A scores in female students (r=0.16, P<0.05). To sum up, the longer the sleep duration, the lower the degree of stress, and the quality of meals which can be said to be a significant finding for high school students.