• Journal of Korean Clinical Health Science
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• v.3 no.2
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• pp.320-327
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• 2015

Purpose. This study was conducted to provide basic data for decrease campus life stress investigated survey on the socio-demographic characteristic and campus life stress of the dental hygiene students. Methods. The research subjects are the total 220 and it was analyzed with structured questionnaires. The collected data was analyzed by IBM SPSS ver. 20.0, a statistical program (IBM Co., Armonk, NY, USA) for the frequency and percentage, ANOVA, Regression. The result is as following Results. The campus life stress was statistically significant differences by in case of poor family reason (${\beta}$=0.287), the fourth grader(${\beta}$=0.151), pocket money a month(${\beta}$=-0.136). Conclusions. As the results of the reasearch, it is necessary support and expansion plan with systemized cooperation between the government and school to state scholarship, living expenses and worker's scholarship for decrease the campus life stress.

• The Journal of Korean Society for School & Community Health Education
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• v.3
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• pp.35-58
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• 2002

This research attempted to investigate the real state of adolescent smoking and drinking, and to study how stress influences on smoking and drinking of high school students. This data was collected from 837 first and second grade students in a vocational high school in Go-yang city, Gyeonggi province. Data analysis consisted of frequency, percentage, Chi-square, T-test, step-wise regression analysis, using SPSSWIN. The results of analysis were as follows: First, 51.7% of the students have never smoked, while 48.3% have experienced smoking. Most students started smoking in the second year of the middle school, though 17.6% of the smokers already started in the elementary school. The strongest motive of initial smoking was curiosity, next the inducement of friends, and 10.9% of them smoked to get rid of stress. Their favorite place for smoking was in the order of the entertainment centers, schools, and private academies. They personally purchased cigarettes mostly at the store. Most of them smoked less than 5 cigarettes a day, but 3.7% smoked more than a pack of cigarettes a day, usually with friends rather than alone. Second, the ratio of drinking was relatively high 78.1%, and their initial drinking experience was most frequent at the third year of the middle school. The initial motive of drinking was mostly curiosity and the inducement of friends, but 10.7% of them started drinking to reduce stress and anxiety. The places for buying alcohol and drinking were bars or restaurants. The ratio of habitual drinking was 45.1%, and the ratio of irregular drinking was 53.3%. 1.8% of the drinking students enjoyed drinking everyday. The amount of drinking varied from half a bottle to two bottles of Soju, and the drinking problem was serious to see that 11% of them drank more than two bottles at a time. Because 84.4% drank in groups with friends, a thorough and systematic supervision and education of the peer group drinking is essential. Third, as for the relationship between personal matters and smoking, it was found that there was a positive relation between smoking and sex, but there was no correlation between smoking and school years. Adolescent smoking was also related with scholastic achievement, the number of friends, and the existence of parents. Fourth, as for the relationship between personal matters and drinking, it was found that there was no correlation between drinking and sex, but there was a positive relation between drinking and school years. Fifth, the average index of stress was students themselves(2.58), school life(2.53), family life(2.19), friends(2.00), and the total index of stress was 2.33. Sixth, there appeared a marginal negative correlation between stress and 'drinking and smoking' in Pearson coefficient of correlation r to see the influence of stress on smoking and drinking. The difference of the average index of stress according to smoking and drinking bears meaningful difference for all students, smokers and non-smokers, drinkers and abstainers in students themselves, school life, family life, friends, and total stress. Smoking has an effect on family life most, school life next, and drinking has an effect on school life most, family life next, with the explanation power of 11% and 9% respectively, in a regression analysis to analyze the factors influencing on smoking and drinking among the factors of stress.

• The Journal of Korean Society for School & Community Health Education
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• v.9 no.1
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• pp.127-142
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• 2008

Objectives: This study was conducted to analyze the stress level of teachers and their management measures, the school environments affecting on the characteristics of teachers and how the health status of school teachers have effect on the stress level of school teachers in our nation. Methods: The study conducted to 900 high school teachers in Seoul, Busan, Incheon, Kwangju and Daejeon. The investigation was carried out for 5 months from March 10 to July 10, 2007. Results: The stress level of test subjects was $15.55{\pm}3.14$ in 30 point scale (51.8 in 100 point scale). The overall level scored 3.71 in 8 point scale (46.4 in 100 point scale), and the average of stress management methods was 15.51 in 36 point scale (55.8 in 100 point scale). Therefore, stress management methods should be developed to solve stress and to reduce the causes of stress variables of high school teachers to teach students healthily in good health status without stress, which can allow us to have healthy families and society though the ripple effects. In addition, the related governments, organizations, related experts and teachers should take effort by paying more attention to increase the life quality of teachers to enjoy healthy life.

• Animal cells and systems
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• v.4 no.1
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• pp.71-76
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• 2000

The aim of this study was to investigate expression patterns of the prolactin (PRL) and c-fos genes by 17$\beta$-estradiol (17$\beta$-E) and stress in the mouse pituitary. In the pituitary, the levels of PRL mRNA were found high with some fluctuation at 30, 50, and 90 min whereas the levels of PRL mRNA were low at 120 min when ovariectomized female mice were injected with 17$\beta$-E or vehicle. PRL mRNA levels began to increase again at 4 h and remained high up to 24 h only in the 17$\beta$-E- treated mice. The overall changes in c-fos mRNA by 17$\beta$-E were very similar to those in PRL mRNA in the pituitary. Subsequent study revealed that these high initial levels of PRL and c-fos mRNAs were caused by stress during Injection, not by 17$\beta$-E, since vehicle injection alone into the ovariectomized mice could increase the levels of PRL and c-fos mRNAs. The stress-induced elevations of PRL and c-fos mRNAs were inhibited by bromocriptin, a dopamine agonist, suggesting that the dopaminergic system is involved in the action route of injection stress. In addition, the induced levels of c-fos mRNA by 17$\beta$-E and stress in the pituitary were very low compared with those in the uterus. The time course changes in c-fos mRNA level were different between the pituitary and uterus. Taken together, these data indicate that PRL and c-tos gene expression in the pituitary are regulated by 17$\beta$-E and stress in a parallel manner, supporting the notion that c-Fos plays a role in regulation of PRL gene expression.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.6
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• pp.2828-2838
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• 2013

The purpose of this study was to measure the level of psychosocial stress, anxiety and depression symptoms among college students, and to reveal its related factors. The survey was filled out by 551 students from Daejon City from April 1, 2012 to July 30, 2012. The independent variables of the questionnaire were socio-demographic characteristics, family life, school life, and other variables health related while the dependent variables were psychosocial stress, anxiety and depression symptoms. As a results, 22.7% of the study subjects were in the high-risk stress group, 15.6% of study subject were in the anxiety disorder group, and 22.1% were in the mild to moderate depression group. In addition, its related factors were influenced by a variety of factors such as gender, family income, satisfaction of family life, grades, social life, satisfaction of school life, subjective sleep quality, subjective health status. Psychosocial stress was significantly influenced by socio-demographic characteristics and family life variables, while anxiety and depression symptoms were influenced more so by psychosocial stress. In order to lower the level of psychosocial stress, anxiety and depression symptoms of college students, the development of programs that monitor the psychosocial stress, socio-demographic characteristics, family life variables, and school variables is imperative.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.9
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• pp.483-492
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• 2016

This study was conducted to identify the correlation between the school-life stress, depression and college adjustment of dormitory residents, in order to provide the basic data needed to establish a strategy to improve the adjustment of college students. The subjects were 210 students in Korea. The data were collected using a self-report questionnaire from September 13 to 19, 2014, and analyzed by frequency, t-test, ANOVA and Pearson's correlation using the SPSS Win 21 program. The school-life stress, depression and college adjustment of the students residing in the dormitory on a 5-point scale were 2.43, 1.88 and 3.81, respectively. School-life stress had a significant positive correlation with depression (r=.639, p<.001) and significant negative correlation with college adjustment (r=-.709, p<.001). Depression had a significant negative correlation with college adjustment (r=-.788, p<.001). Those students with a higher school-life stress showed higher levels of depression and lower levels of college adjustment. Those students with a higher level of depression showed a lower level of college adjustment. Therefore, it is necessary to develop and test a suitable program in order to understand the differences between psychological adjustment based on gender, and to decrease school-life stress and depression and increase college adjustment.

• Proceedings of the Korean Society of Plant Biotechnology Conference
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• 2005.11a
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• pp.162-162
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• 2005

• Biomolecules & Therapeutics
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• v.32 no.5
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• pp.640-646
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• 2024

Hair growth cycles are mainly regulated by human dermal papilla cells (hDPCs) and human outer root sheath cells (hORSCs). Protecting hDPCs from excessive oxidative stress and hORSCs from glycogen phosphorylase (PYGL) is crucial to maintaining the hair growth phase, anagen. In this study, we developed a new PYGL inhibitor, hydroxytrimethylpyridinyl methylindolecarboxamide (HTPI) and assessed its potential to prevent hair loss. HTPI reduced oxidative damage, preventing cell death and restored decreased level of anagen marker ALP and its related genes induced by hydrogen peroxide in hDPCs. Moreover, HTPI inhibited glycogen degradation and induced cell survival under glucose starvation in hORSCs. In ex-vivo culture, HTPI significantly enhanced hair growth compared to the control with minoxidil showing comparable results. Overall, these findings suggest that HTPI has significant potential as a therapeutic agent for the prevention and treatment of hair loss.

• Journal of Life Science
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• v.22 no.8
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• pp.1132-1136
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• 2012

Many kind of cell stresses induce gene expression of unfolded protein response (UPR)-associated factors. This study demonstrated that up- and down-regulation of gene expression of endoplasmic reticulum (ER) stress chaperones and ER stress sensors was induced by immobilization stress in the rat organs (adrenal gland, liver, lung, muscle). However, no statistically significant regulation was detected in the others (heart, spleen, thymus, kidney, testis). The results are the first to show that immobilization stress induces UPR associated gene expression, will help to explain immobilization stress-associated ER stress.

• The Korean Journal of Health Service Management
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• v.6 no.4
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• pp.131-142
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• 2012

The purpose of the study was to identify the mediating effects of health promoting lifestyle in the relationship between life stress and adaptation to college life of health department college students. The data was collected for 10 days form sept. 3 to 14, 2012. Among a total of 351 cases of questionaries, only 342 cases were used. To data were analyzed by frequency, t-test, ANOVA, correlation and a hierarchical multiple regression analysis as suggested by Baron and Kenny(1986) using PASW statistics 18.0. From the analyses, there was a negative relationship between life stress and adaptation to college life but a positive relationship between health promoting lifestyle and adaptation to college life. There was a partial mediating effect of health promoting lifestyle between life stress and adaptation to college life. The results indicate a need to develop programs that effectively promote the health promoting lifestyle of health department college students to decrease life stress and maximize adaptation to college life.