• Journal of Food Hygiene and Safety
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• v.25 no.3
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• pp.209-214
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• 2010

Metastasis is the primary cause of from breast cancer mortality. Cell migration and invasion play important roles in neoplastic metastasis. Matrix metalloproteinase-9 (MMP-9), which degrades the extracellular matrix (ECM), plays an important role in cancer cell invasion. NF-${\kappa}B$ is transcription factor important in the regulation of MMP-9, as the promoter of MMP-9 gene contains binding sites for NF-${\kappa}B$. Brazilin, an active component of sappan wood (Caesalpinia sappan), decreases TPA-induced MMP-9 expression and invasion in MCF-7 cells. Also, brazilin suppressed NF-${\kappa}B$ activation in TPA-treated MCF-7 cells. Taken together, we demonstrated that the inhibition of TPA-induced MMP-9 expression and cell invasion by brazilin is mediated by the suppression of the NF-${\kappa}B$ pathway in MCF-7 cells. This result suggest brazilin provide a potential therapeutic app roach for the treatment of breast cancer.

• Journal of the Korean Wood Science and Technology
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• v.45 no.3
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• pp.297-307
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• 2017

This research was performed to use recycling wood fiber from waste MDF as raw materials for manufacturing of interior decorative accessories. Virgin fiber of Pinus rigida for manufacturing MDF and recycling fiber from manufactured MDF with virgin fiber were dyed by using reactive dyes (Bis-monochlorotriazine and Vinyl sulfone type), vat dyes (Anthraquinone type), direct dyes (Diazo type) such as red, yellow and blue, and natural dyes using gardenia or sappan wood, and they were examined to evaluate their dyeing properties and sunlight fastness. The hue of virgin fiber and recycling fiber were 4.2YR, and 4.4YR, respectively, which showed red-yellowish color. The recycling fiber looked a little darker than the virgin fiber, where $L^*$ values of the recycling fiber showed a little lower. Reactive, vat and direct dyes dyed well both the virgin and recycling fibers. The recycling fiber showed a little higher values of colour yield and a little lower in $L^*$, but it seemed that there was no significant difference. The Hue values of the recycling fiber and the virgin fiber dyed with sappan wood were 4.4YR and 4.0YR, showing no difference between/after dyeing. However the Hue values of the recycling fiber and the virgin fiber dyed with gardenia were 7.4YR and 6.9YR, respectively. Those values were much higher than the values of the fibers dyed with other chemical dyes. But the fibers dyed with gardenia showed poor sunlight fastness.

• Textile Coloration and Finishing
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• v.9 no.6
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• pp.33-41
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• 1997

This paper surveys the extraction condition of polygenetic natural dye, Sappan Wood and the effect of ash to the dyeability and fastness. The appropriate time for extracting Sappon Wood was 1hour. The pH was increased as the amount of ash increase. The pH was nearly invariable according to the time of ash solution, the extracting times and temperature. Absorbance of dyeing fabrics was about 480nm. From the result of K/S value determination of fabrics, 10g/$\ell$ quantity of ash was surfficient for treatment and the amount of Sappon Wood was in 100% o.w.f.. K/S value of fabrics pre-mordanted or post-mordanted were higher than that of fabrics simultaneous mordanted.K/S value was increased as pH of mordanting bath decrease and pre-mordanting and post-mordanting fabrics increased the amount of absorption (K/S value) compared with non-mordanted fabrics. It was found that pH of mordanting bath affected the amount of absorption and color change of dyed fabrics. Light fastness of fabric dyed was very poor and the fastness of fabric dyed was not influenced by the mordanting conditions and methods.

• Journal of dental hygiene science
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• v.12 no.3
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• pp.209-215
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• 2012

Somok, the heart wood of Caesalpinia sappan is used in traditional Chinese medicine. This study was performed to investigate the effect of growth and culture conditions of brazilin from C. sappan against S. mutans ATCC 25175. The bacteria were cultured in brain heart infusion (BHI) broth, and then incubated under 5% $CO_2$ at $37^{\circ}C$ for 18-24 hours. The effect of brazilin against S. mutans was confirmed under the changes of the culture conditions, such as growth curve and the change of pH, protein, and total carbohydrate. The growth of S. mutans in control medium was the highest at 24 hr, while brazilin-added medium (0.3 mg/ml) showed maximum growth at 32 hr. The pH values of the control medium was 5.25 at 16 hr, but the media supplemented with brazilin (0.3 mg/ml) was 7.0 at 16 hr. The amounts of total carbohydrate of the control medium was 11 mg/ml at 8 hr, but the brazilin-added media (0.3 mg/ml) was 18 mg/ml at 8 hr. In the protein change of the culture medium, the control culture broth and the brazilin supplemented-cultures was 2.4 mg/ml and 2.54 mg/ml at 24 hr, respectively. Polysaccharide contents of the control medium and test media were 3 mg/ml and 2 mg/ml at 8 hr, respectively. Thus, the application of C. sappan can be considered a useful and practical material for the prevention of dental caries.

• Textile Coloration and Finishing
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• v.22 no.4
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• pp.314-324
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• 2010

The purpose of this study is to obtain the dyed-fabrics of the elaborate patterns using the natural dye powders extracted from Galla Rhois, Sophorae Flos Immaturus, Clove, Sappan Wood, Madder, Log Wood and Japanese Green Alder. Specific informations on the separation and powder-making of each colorant were disclosed. Appropriate printing paste preparation and printing conditions including the viscosity and mordant concentration in the printing paste were investigated. The dyeability and colorfastness of the screen-printed silk fabrics with the colorant powders were discussed in terms of practical applicability. The deodorization and antimicrobial activities of the silk fabrics screen-printed with natural dyes were also assessed.

• Journal of Fashion Business
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• v.26 no.3
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• pp.87-97
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• 2022

This study investigated the dyeability and color change of the natural dyes of SeaCell, a biodegradable functional fiber that is permanently added to cellulose fibers with natural additives extracted from seaweeds. The natural dyes used in the study are five dyes. Gardenia and turmeric, which are yellow-based natural dyes, Sappan wood and Lac, which are red-based natural dyes, and Indigo, a blue-based natural dye, were selected. The dyeability and color change according to the change of the mordant conditions and the number of times of dyeing were investigated. In addition, the dyeing properties and colors of cotton and silk fibers were compared under the same dyeing conditions as SeaCell. The study results are as follows. It was found that SeaCell had lower dyeing properties than silk, a protein fiber, in gardenia, sappan wood, and lac dyes, but had higher dyeing properties than cotton with the same cellulose component as SeaCell fibers. In the case of turmeric, it showed higher dyeing properties than cotton except for the no mordant condition. In the case of Indigo dye, SeaCell shows the best dyeability, indicating that it is a very suitable fiber for Indigo dyeing. As sustainable functional fibers are continuously developed in the future, natural dyes that are environmentally friendly and human-friendly are actively introduced and commercialized, and it is expected that they can be used as reference materials.

• Journal of dental hygiene science
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• v.10 no.5
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• pp.365-372
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• 2010

Caesalpinia sappan L. has long been commonly used in oriental folk medicines and as dyes materials. To investigate the antioxidative activities and antiproliferation effects of brazilin from C. sappan heart wood, the MeOH soluble extract was successively fractionated by using hexane, $CHCl_{3}$, EtOAc, BuOH, MeOH, and $H_{2}O$. In these fractions, we were purified brazilin from EtOAc fraction which partitioned to 3.94% of the highest yields. The effects of brazilin and the extracts on human oral carcinoma cells (KB) by MTT assay and their antioxidant activities by DPPH, TCA assay and Fenton reaction were tested. The results showed that the brazilin could inhibits the proliferation of KB cells and obviously decreased the production of nitric oxide of the cells. When the concentration of the brazilin reached to $100\;{\mu}g/ml$, the inhibition percentage of the cell growth was about 60%. In assay on antioxidant activities, The results showed that brazilin exhibit the highest capacity of DPPH free radical scavenging effects among tested extracts. When the concentration of brazilin reached to 1 mg/ml, the lipid peroxide inhibition and radical inhibition activities were determined to be 65.0% and 85.8%, respectively. These results are suggest that brazilin have stronger antiproliferation effect on KB cell and antioxidant properties.

• Textile Coloration and Finishing
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• v.28 no.3
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• pp.208-218
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• 2016

This study investigated the effects of the working mechanisms of proteins, mordants, and dyes, as well as the mordanting order, on dye uptake by silk fabric pre-treated with proteins and dyed with freeze-dried sappan wood water extract. Soybean protein and sodium caseinate were used as the proteins. 1. When Al mordants were not used, the dyeability of the fabrics increased upon protein pre-treatment as compared to the case without treatment. 2. Dyeing with protein pre-treatment, followed by mordanting, led to the highest dye uptake, and the optimal protein concentration was 5%. 3. The K/S values slightly decreased with an increase in the dyeing temperature, and the fabric turned dark red in color when dyeing was carried out at increasing temperature. Fabrics showed the highest dye uptake at $40^{\circ}C$. 4. Regarding the effect of time, the K/S values of the fabrics with and without protein treatment showed almost no increase after the initial dyeing time of 10min; further, there was hardly any difference in the cases with and without protein pre-treatment. 5. In case of protein pre-treatment fabrics, the washing fastness was level 2. The dry cleaning fastness showed very excellent result with level 4-5. The rubbing fastness was better in dry rubbing than in wet rubbing of the fabrics. For the light fastness, all dyed fabrics showed low fastness.

• Herbal Formula Science
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• v.12 no.1
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• pp.159-175
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• 2004

The inhibitory effects of 207 oriental medicines and 19 oriental prescriptions on the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical were examined. The most effective oriental medicines were the fruit of Terminalia chebula, followed in order by the seed of Areca catechu, the heart wood of Caesalpinia sappan, the pericarp of Castanea crenata, the seed of Nelumbo nucifera, Rhus galls, the root of Sanguisorba officinalis, and the bark of Betula platyphylla at the concentration of 10 ${\mu}g$／mL. Of the 19 oriental prescriptions, Buyeonsan and Samsinhwan showed the potent scavenging activities of 88% and 71% on DPPH radical at the concentration of 5 ${\mu}g$／mL, respectively.

• Journal of the Korea Furniture Society
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• v.23 no.4
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• pp.407-414
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• 2012

In order to develop the end use of cylindrical laminated veneer lumber (LVL) such as wooden crafts, the light resistance properties of natural dye-colored and finished cylindrical LVL was investigated. The study results were as follows; The cross section of LVL showed the higher light resistance than its tangential section, and the light resistance also increased with surface coated. On the other hand, LVL specimen were colored by 9 natural dyes of amur cork-tree etc., and the natural and apparent hue harmonized with wood was found after coating and light resistance test. Particularly, The dyes extracted from amur cork-tree, persimon and sappan wood showed orange color, reddish brown and red color respectively, giving an accenting effect to original wood color.