• Title/Summary/Keyword: SVP

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A Case Series of Snake Venom Pharmacopuncture for Chemotherapy-Induced Peripheral Neuropathy: A Retrospective Observational Study

  • Song, Si Yeon;Bae, Kyeore;Shin, Kwhang Ho;Yoo, Hwa-Seung
    • Journal of Pharmacopuncture
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    • v.20 no.4
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    • pp.280-286
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    • 2017
  • Objective: This case series aims to report the efficacy and the safety of using snake venom pharmacopuncture (SVP) for chemotherapy-induced peripheral neuropathy (CIPN). Methods: Three heterogeneous cancer (1 endometrium, 1 cervix, and 1 prostate cancer) patients were referred to the East-West Cancer Center (EWCC), Dunsan Korean Medicine Hospital of Daejeon University, from August 02, 2017, to September 15, 2017, for treatment with SVP, and they were treated with SVP 4 times, 6 times, and 8 times, respectively. During the treatment period, the efficacy of SVP therapy was assessed by using the Numerical Rating Scale (NRS) and the Common Terminology Criteria for Adverse Events (CTCAE), and the stability was evaluated by using blood tests. Following each session, all patients were examined closely for any allergenic responses or adverse effects. Results: All patients showed noticeable improvements of their NRS and CTCAE scores. Except for bleeding and bruising at the SVP injection site, no major side effects were noted. One of the patients reported mild chilling and a sore throat after receiving the second treatment; those symptoms went away after a few hours. No hematologic toxicity, hepatotoxicity, or nephrotoxicity was found on the blood test. Conclusion: The results of this research suggest positive potential benefits of using SVP for treating patients with CIPN. Also, the excellent safety results of SVP seen in this research should lead to larger clinical trials aimed at developing SVP into a potential intervention for managing patients with the symptoms of CIPN.

Development of a chatbot for school violence prevention among elementary school students in South Korea: a methodological study

  • Kyung-Ah Kang;Shin-Jeong Kim;Byoung-doo Oh;Yu-Hyeon Kim
    • Child Health Nursing Research
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    • v.30 no.1
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    • pp.45-53
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    • 2024
  • Purpose: This study develops a chatbot for school violence prevention (C-SVP) among elementary school students. Methods: Among the analysis, design, development, implementation, and evaluation (ADDIE) models, ADD phases were applied to develop a C-SVP. Students' learning needs were identified by constructing content with a design that attracted their attention. Subsequently, a formative evaluation was conducted on the developed C-SVP to test its applicability by ten elementary school students targeting the 5th and 6th grades. Results: The chatbot was designed using KakaoTalk and named "School Guardian Angel." The formative evaluation revealed that the developed C-SVP was easily accessible and useful for elementary school students. Conclusion: The developed C-SVP is expected to be effective in preventing violence among elementary school students. However, further research involving children of various age groups is required.

Design of Architecture of Programmable Stack-based Video Processor with VHDL (VHDL을 이용한 프로그램 가능한 스택 기반 영상 프로세서 구조 설계)

  • 박주현;김영민
    • Journal of the Korean Institute of Telematics and Electronics C
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    • v.36C no.4
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    • pp.31-43
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    • 1999
  • The main goal of this paper is to design a high performance SVP(Stack based Video Processor) for network applications. The SVP is a comprehensive scheme; 'better' in the sense that it is an optimal selection of previously proposed enhancements of a stack machine and a video processor. This can process effectively object-based video data using a S-RISC(Stack-based Reduced Instruction Set Computer) with a semi -general-purpose architecture having a stack buffer for OOP(Object-Oriented Programming) with many small procedures at running programs. And it includes a vector processor that can improve the MPEG coding speed. The vector processor in the SVP can execute advanced mode motion compensation, motion prediction by half pixel and SA-DCT(Shape Adaptive-Discrete Cosine Transform) of MPEG-4. Absolutors and halfers in the vector processor make this architecture extensive to a encoder. We also designed a VLSI stack-oriented video processor using the proposed architecture of stack-oriented video decoding. It was designed with O.5$\mu\textrm{m}$ 3LM standard-cell technology, and has 110K logic gates and 12 Kbits SRAM internal buffer. The operating frequency is 50MHz. This executes algorithms of video decoding for QCIF 15fps(frame per second), maximum rate of VLBV(Very Low Bitrate Video) in MPEG-4.

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Mesotherapy with Snake Venom Pharmacopuncture to Treat Hand Eczema: Two Cases Report

  • Kim, Sungha;Lee, Jinbok;Shin, Minseop
    • Journal of Pharmacopuncture
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    • v.23 no.4
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    • pp.273-276
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    • 2020
  • Hand eczema is a recurrent and resistant disease that seriously affects the quality of life of patients; currently, there are no ideal treatments for hand eczema. Here, we describe two patients who presented with hand eczema to illustrate the potential efficacy of mesotherapy with snake venom pharmacopuncture (SVP). A 23-year-old woman (Case 1) and a 47-year-old woman (Case 2) presented to the clinic with symptoms of pruritic rash, blisters, and itchiness on both the hands and the left hand, respectively. Both patients were diagnosed with hand eczema based on the physical examination of blisters and redness only on the hands. The patients underwent 1 month (Case 1) and 1 week (Case 2) of mesotherapy with SVP. After treatment, the lesions completely improved and did not recur at 1 year of follow-up. These outcomes suggest that mesotherapy with SVP may be effective for the resolution of hand eczema; however, further research is needed to confirm these findings.

Effect of Sound Velocity on Bathymetric Data Aquired by EM120(multi-beam echo sounder) (EM120(multi-beam echo sounder)을 이용한 지형조사 시 적용되는 해수 중 음속 측정의 중요성; 수중음속 측정장비의 특성 비교)

  • Ham, Dong-Jin;Kim, Hyun-Sub;Lee, Gun-Chang
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.13 no.3
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    • pp.295-301
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    • 2008
  • Bathymetric data collected using a multi-beam echo sounder during marine scientific survey is essential for geologic and oceanographic research works. Accurate measurment of sound velocity profile(SVP) in water-column is important for bathymetric data processing. SVP can vary at different locations during the survey undertaken for wide areas. In addition, an observational error can occur when different equipments(Sound Velocity Profiler, Conductivity Temperature Depth, eXpendable BathyThermograph) are used for measuring SVP at the same water column. In this study, we used an MB-system software to show changes in bathymetry caused by variation of SVP. The analyses showed that the sound velocity(SV) changes due to the depth and thickness of thermocline had more significant effects on the resulting bathymetric data than those of surface mixed layer. The observational errors between SVP measuring instruments did not cause much differneces in the processed bathymetric data. Bathymetric survey line is better to be established to the direction that the change of temperature can be minimize to reduce the variation of SVP during the data acquisition along the survey line.

A Study on NTRUSign security to prevent script attacks (스크립트 공격을 막기 위한 NTRUSign 보안 연구)

  • Bae, Sung-Hyun;Jeong, Jong-hyeog
    • Journal of IKEEE
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    • v.23 no.1
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    • pp.200-206
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    • 2019
  • Recently, there is a growing preference for a fast and secure cryptographic protocol that is applicable to Internet of things environments. Among the lattice-based cryptographic algorithms, the NTRU cryptosystem is secure by virtue of the shortest vector problem (SVP) and the closest problem(CVP), which is a problem of finding very short vectors and closest vector. NTRUSign, an electronic signature based on this cryptographic algorithm, has been proposed and proved unsafe for script attacks. In this paper, we propose a security protocol using a symmetric key algorithm by securing a shared key using key exchange. Therefore, the attacker can not compute the key value and intends to propose a more secure digital signature.

Improvement in Inefficient Repetition of Gauss Sieve (Gauss Sieve 반복 동작에서의 비효율성 개선)

  • Byeongho Cheon;Changwon Lee;Chanho Jeon;Seokhie Hong;Suhri Kim
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.33 no.2
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    • pp.223-233
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    • 2023
  • Gauss Sieve is an algorithm for solving SVP and requires exponential time and space complexity. The terminationcondition of the Sieve is determined by the size of the constructed list and the number of collisions related to space complexity. The term 'collision' refers to the state in which the sampled vector is reduced to the vector that is already inthe list. if collisions occur more than a certain number of times, the algorithm terminates. When executing previous algorithms, we noticed that unnecessary operations continued even after the shortest vector was found. This means that the existing termination condition is set larger than necessary. In this paper, after identifying the point where unnecessary operations are repeated, optimization is performed on the number of operations required. The tests are conducted by adjusting the threshold of the collision that becomes the termination condition and the distribution in whichthe sample vector is generated. According to the experiments, the operation that occupies the largest proportion decreased by62.6%. The space and time complexity also decreased by 4.3 and 1.6%, respectively.

Using Internet and an Alleviation of Information Gap (인터넷 이용과 정보격차 완화)

  • 이순재
    • Proceedings of the Korean Society for Information Management Conference
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    • 1999.08a
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    • pp.77-80
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    • 1999
  • 정보기술의 무한한 잠재력에도 불구하고 이로 인한 문제점들이 부각되고 있는 바, 그 수용여부에 따라 사회계층간 심각한 정보격차 현상이 나타나고 있다. 그러나 정책격차는 인터넷 이용을 통해 상당부분 완화시킬 수 있으며, 실제로 미국의 경우를 FIND/SVP의 통계조사를 토대로 그 실태를 살펴보고자 한다.

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Settlement analysis of pile cap with normal and under-reamed piles

  • Kumar, Madisetti Pavan;Raju, P. Markandeya;Jasmine, G. Vincent;Aditya, Mantini
    • Computers and Concrete
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    • v.25 no.6
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    • pp.525-535
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    • 2020
  • The use of pile foundations has become more popular in recent years, as the combined action of the pile cap and the piles can increase the bearing capacity, reduce settlement, and the piles can be arranged so as to reduce differential deflection in the pile cap. Piles are relatively long, slender members that transmit foundation loads through soil strata of low bearing capacity to deeper soil or rock strata having a high bearing capacity. In this study analysis of pile cap with considering different parameters like depth of the pile cap, width and breadth of the pile cap, type of piles and different types of soil which affect the behaviour of pile cap foundation is carried out by using Finite Element Software ANSYS. For understanding the settlement behaviour of pile cap foundation, parametric studies have been carried out in four types of clay by varying pile cap dimensions with two types of piles namely normal and under-reamed piles for different group of piles. Furthermore, the analysis results of settlement and stress values for the pile cap with normal and under-reamed piles are compared. From the study it can be concluded that settlement values of pile cap with under-reamed pile are less than the settlements of pile cap with normal pile. It means that the ultimate load bearing capacity of pile cap with under-reamed piles are greater than the pile cap with normal piles.

Comparative Study of Particulate Contamination from Ampoule and Prefilled Syringe (앰플 및 1회용 주사용기에서의 미립자 혼입에 관한 비교연구)

  • Shim, Chang-Koo;Han, Yong-Hae;Kwon, Don-Sun
    • Journal of Pharmaceutical Investigation
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    • v.21 no.3
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    • pp.155-160
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    • 1991
  • Particulate is the foreign insoluble material in injectable solution inadvertently present in a given product. Considerable efforts have been made to avoid or minimize particulate contamination by pharmaceutical manufacturers during the production of parenteral products. Particulate contamination of the parenteral products can occur mainly during the opening (cutting) the container immediately before clinical use. In this study, particulate contamination generated during the opening process of ampoules (conventional type, 1-point and color-break ampoules) was compared with that of a prefilled injectable container (prefilled syringe). The particles were examined under a microscope after filtration of the total fluids in the containers. Particles having wide range of size distribution were found from all the ampoules tested. The contamination from the I-point ampoule and colorbreak ampoule was much less than from the conventional ampoule. Glass particles generated by cutting the glass-made ampoules seemed a principal source of the particulate contamination. The glass-partiaulte contamination could be improved substantially by replacing the ampoule containers with the prefilled syringe. Prefilled syringe, which can be used without any cutting process. did not generate particulates during the use. Therefore, it was concluded that prefilled syringe is most preferable container for the small volume parenteral (SVP) fluids in terms of particulate contamination.

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