• Title/Summary/Keyword: SUSAN

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Residents' Preference for Spatial Features in Sitting Areas at Assisted Living Facilities - Focused on direct or indirect social interaction for older adults -

  • Lee, Min-Ah;Rodiek, Susan D.
    • International Journal of Human Ecology
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    • v.14 no.1
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    • pp.87-102
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    • 2013
  • This study investigated residents' preferences for spatial features of sitting areas in assisted living facilities, and provides recommendations for planning sitting areas to support residents' spatial preferences and social interaction. The study participants were 69 residents of eight assisted living facilities (30+ resident capacity), located in south central Texas. A photographic comparison method was used, in which residents were shown 20 matched pairs of photos, with a single feature digitally modified in each pair, and asked to select which environmental representation they preferred. The hypothesized spatial characteristics were identified in practice based literature as those that may encourage usage of sitting areas: viewability, variety, homelikeness, and privacy. Most of the hypothesized features were preferred by participants, with the highest preference found for non-institutional furniture arrangements and naturalness, followed by increasing enclosure and variety of seating. Preference was less significant for domestic cues such as carpeted floors, divided light windows, and boundaries defined by different colored material or columns, possibly due to their physical impairments or preference for visual openness. Participants' level of mobility assistance was significantly related to their preference for some features, such as seating with people-watching capability, and carpeted floors. The findings have implications for facility architects and administrators engaged in resident-oriented spatial planning.

Gall structure and specificity in Bostrychia culture isolates (Rhodomelaceae, Rhodophyta)

  • West, John A.;Pueschel, Curt M.;Klochkova, Tatyana A.;Kim, Gwang Hoon;De Goer, Susan;Zuccarello, Giuseppe C.
    • ALGAE
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    • v.28 no.1
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    • pp.83-92
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    • 2013
  • The descriptions of galls, or tumors, in red algae have been sparse. K$\ddot{u}$tzing (1865) observed possible galls of Bostrychia but only presented a drawing. Intensive culture observations of hundreds of specimens of the genus Bostrychia over many years have revealed that galls appeared in only a small subset of our unialgal cultures of B. kelanensis, Bostrychia moritziana/radicans, B. radicosa, B. simpliciuscula, and B. tenella and continued to be produced intermittently or continuously over many years in some cultures but were never seen in field specimens. Galls appeared as unorganized tissue found primarily on males and bisexuals, but occasionally on females and tetrasporophytes. The gall cells usually were less pigmented than neighboring tissue, but contained cells with fluorescent plastids and nuclei. The galls were not transferable to other potential hosts. Galls could be produced from gall-free tissue of cultures that originally had galls even after transfer to new culture dishes. Electon microscopy of galls on one isolate (3895) showed that virus-like particles are observed in some gall cells. It is possible that a virus is the causative agent of these galls.

The study on the number of customer to be estimated when cultural theme park is constructed in Busan (부산지역 역사ㆍ문화 테마파크 조성을 위한 내ㆍ외래 관광객의 수요추정 기초조사연구)

  • 최승복;오세두
    • Archives of design research
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    • v.17 no.2
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    • pp.33-42
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    • 2004
  • It is a matter of fact that Susan, doesn't have enough systematic history and culture, has face on very difficult situation. A competitive and fashionable tourist theme park need to be constructed to develop their historical theme park, and to make own culture which is related to Busan' tradition. The subject of this study is to suggest the basic knowledge about number of customer to be estimated When cultural theme park is built up. The questionaries to customer is consist of the propensity of leasure, the use of similar facility, the type of theme park, and inclination of visitation to foreign and domestic tourist.

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Positional Cloning and Phenotypic Characterization of a New Mutant Mouse with Neuronal Migration Abnormality

  • Park, Chankyu;Ackerman, Susan-L
    • Proceedings of the Korean Society of Developmental Biology Conference
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    • 2001.10a
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    • pp.14-17
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    • 2001
  • Positional clonging (map-based cloning) of mutations or genetic variations has been served as an invaluable tool to understand in-vivo functions of genes and to identify molecular components underlying phenotypes of interest. Mice homozygous for the cerebellar deficient folia (cdf) mutation are ataxic, with cerebellar hypoplasia and abnormal lobulation of the cerebellum. In the cdf mutant cerebellum approximately 40% of Purkinje cells are ectopically located within the white matter and the inner granule cell layer (IGL). To identify the cdf gene, a high-resolution genetic map for the cdf-gene-encompassing region was constructed using 1997 F2 mice generated from C3H/HeSnJ-cdf/cdf and CAST/Ei intercross. The cdf gene showed complete linkage disequilibrium with three tightly linked markers D6Mit208, D6Mit359, and D6Mit225. A contig using YAC, BAC, and P1 clones was constructed for the cdf critical region to identify the gene. A deletion in the cdf critical region on chromosome 6 that removes approximately 150 kb of DNA selection. cdf mutant mice with the transgenic copy of the identified gene restored the brain abnormalities of the mutant mice. The positional cloning of cdf gene provides a good example showing the identification of a gene could lead to finding a new component of important molecular pathways.

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An Information-Intensive Approach to the Molecular Pharmacology of Cancer

  • John N. Weinstein;Timothy G. Myers;Patrick M. O′Connor;Stephen H. Friend;Albert J. Fornace Jr;Kurt W. Kohn;Tito Fojo;Susan E. Bates;Lawrence V. Rubinstein;N. Leigh Anderson;John K. Buolamwini;Wiliam W. van Osdol;Anne P. Monks;Dominic A. Scudiero;Edward A. Sausville;Daniel W. Zaharevitz;Barry Bunow;Vellarkda N. Viswanadhan;Georage S. Johnson;Robert E. Wittes;Kennety D. Paull
    • Proceedings of the Korean Society for Bioinformatics Conference
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    • 2001.08a
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    • pp.139-149
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    • 2001
  • Since 1990, the National Cancer Institute(NCI) has screened more than 60.000 compounds against a panel of 60 human cancer cell lines. The 50-percent growth-inhibitory concentration (GI$_{50}$) values encode unexpectedly rich, detailed information on mechanisms of drug action and drug resistance. Each compound's pattern is like a fingerprint, essentially unique among the many billions of distinguishable possibilities. These activity patterns are being used in conjunction with molecular structural features of the tested agents to explore the NCI's database of more than 460, 000 compounds, and they are providing insight into potential target molecules and modulators of activity in the 60 cell lines. For example, the information is being used to search for candidate anticancer drugs that are not dependent on intact p53 suppressor gene function for their activity. It remains to be seen how effective this information-intensive strategy will be at generating new clinically active agents.s.

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Erythrolobus australicus sp. nov. (Porphyridiophyceae, Rhodophyta): a description based on several approaches

  • Yang, Eun-Chan;Scot, Joe;West, John A.;Yoon, Hwan-Su;Yokoyama, Akiko;Karsten, Ulf;De Goer, Susan Loiseaux;Orlova, Evguenia
    • ALGAE
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    • v.26 no.2
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    • pp.167-180
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    • 2011
  • The unicellular marine red alga Erythrolobus australicus sp. nov. (Porphyridiophyceae) was isolated into laboratory culture from mangroves in Queensland and New South Wales, Australia. The single multi-lobed red to rose-red plastid has more than one pyrenoid and lacks a peripheral thylakoid. Arrays of small electron dense globules occur along the thylakoids. The nucleus is peripheral with a central to eccentric nucleolus. Each Golgi body is associated with a mitochondrion. The spherical cells are positively phototactic with slow gliding movement. The psaA + psbA phylogeny clearly showed that E. australicus is a distinct species, which is closely related to E. coxiae. The chemotaxonomically relevant and most abundant low molecular weight carbohydrate in E. australicus is floridoside with concentrations between 209 and 231 ${\mu}mol g^{-1}$ dry weight. Traces of digeneaside were also detected. These various approaches help to understand the taxonomic diversity of unicellular red algae.

Unrecorded Fungal Species Isolated from Medicinal Plant Leaves in Korea (약용식물 잎에서 분리한 국내 미기록 진균)

  • Ahn, Geum Ran;Noh, Hyeungjin;Lee, Dong Hyeung;Kim, Susan;Kim, Jun Young;Kim, Seong Hwan
    • The Korean Journal of Mycology
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    • v.47 no.4
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    • pp.319-328
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    • 2019
  • As an effort to explore fungal diversity, fungal survey was undertaken in 2018 in Jangheung, Korea. For the survey, medicinal plant leaves were sampled from Selaginella tamariscina, Serratula coronata ssp. insularis, Scutellaria baicalensis, Scrophularia buergeriana and subjected to fungal isolation. Four unrecorded fungal species, Paraboeremia selaginellae, Colletotrichum camelliae, Alternaria eichhorniae, and Phomopsis capsici were obtained from the survey. This study described their morphological characteristics including colony features formed on media, light microscopic images and molecular characteristics of nucleotide sequences of the ITS and 28S rDNA regions.

Effects of a Breastfeeding Program for Premature Infants on Maternal Stress, Knowledge, and Breastfeeding Behaviors (미숙아 모유수유 프로그램이 미숙아 어머니의 스트레스, 모유수유 지식정도 및 실천에 미치는 효과)

  • Oh, Jin-A;Choi, Mi-Hyang;Kim, Hyun-Hee
    • Korean Parent-Child Health Journal
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    • v.7 no.2
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    • pp.121-132
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    • 2004
  • Purpose: This study aimed to develop a breast feeding program for mothers of premature infants. The program was applied and its effect was evaluated on stress, knowledge and breastfeeding behaviors of premature infant mothers. Method: This study employed a one group pre- and post-test quasi-experimental design. The data were collected from 17 participants from August 15 to October 24, 2004, at a N1CU at D University Medical Center located in Susan, Korea. Data were analyzed by means of frequency, SD, and t-test using SPSS version 10. Result: After the program, participants significantly showed a greater level of knowledge than before the program (t=-5.750, p=.000). No statistically significant differences in stress level scores were found (t=1.453, p=.153). The breastfeeding practice rate was 94.1%: Conclusion: This educational program using a handbook and video had a positive effect on increasing knowledge and practice of breastfeeding among premature infant mothers. It is suggested that this study be replicated with a larger sample size to compare group responses.

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A Study on the Digital Era's Influential Factors on Policy Organizations (디지털시대의 정책조직에 미치는 영향요인에 관한 연구)

  • Lee, Sang-Bum
    • Journal of Digital Convergence
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    • v.6 no.2
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    • pp.33-40
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    • 2008
  • Alvin Toffler는 인류 발전 과정을 세 가지 변화의 물결, 즉 유목 채집 사회에서 농경 사회로의 변화, 산업혁명에 의한 농경 사회에서 산업 사회로의 변화, 그리고 1950년대부터의 후기 산업화 사회로의 변혁으로, 산업 사회에서 정보 사회로의 변혁이 일어나기 시작했으며 탈대량화, 다양화, 지식기반 생산과 변화의 가속이 시작된 시기였다. Herman Maynard와 Susan Mehrtens는 ICT (Information Communication Technology: 휴대폰 등), 인터넷의 발달로 제4의 물결이 시작되고 있다고 주장한다. 이전의 사회 변혁들은 물질 생산이 따르는 가시적인 변혁들이었으나, 디지털 혁명은 시민사회의 참여 확대를 통한 민주주의의 진화된 형태를 가능하게 하고 있다. 지금 우리가 경험하고 있는 제4의 물결의 시작은, 시민사회의 정책 참여와 견제가 효과적이고 효율적으로 이루어지기 시작하는 초고도 정보화 사회의 시작을 의미하며, 정책 결정 자들은 정책 결정 과정에서 그들이 보유하던 절대 영향력의 일부분을 시민사회에 이양됨을 막을 수 없을 것이다. 이러한 대변혁의 시대에 관료주의, Digital Divide, 그리고 시민 참여와의 상관관계를 이해하는 것은 매우 중요하다. 본 논문에서는 시민 참여에 대한 관료주의의 방침과 태도, 제4의 물결의 정책 민주화와 Digital Divide로의 영향 분석을 통하여 정책 결정 자들과 그들의 환경으로의 파급 효과를 논증한다. 본 연구는 이러한 분석과 논증을 통하여, 정책조직들과 시민사회와의 신세기의 바람직한 동반자적 입지 구축에 기여 할 것이다.

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Structure function relationships amongst the purple acid phosphatase family of binuclear metal-containing enzymes

  • Hamilton, Susan
    • Proceedings of the Korean Society for Bioinformatics Conference
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    • 2003.10a
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    • pp.5-5
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    • 2003
  • The purple acid phosphatases comprise a family of binuclear metal-containing enzymes. The metal centre contains one ferric ion and one divalent metal ion. Spectroscopic studies of the monomeric, ${\sim}$36 kDa mammalian purple acid phosphatases reveal the presence of an Fe(III)Fe(II) centre in which the metals are weakly antiferromagnetically coupled, whereas the dimeric, ${\sim}$110 000 kDa plant enzymes contain either Fe(III)Zn(II) or Fe(III)Mn(II). The three dimensional structures of the red kidney bean and pig enzymes show very similar arrangements of the metal ligands but some significant differences beyond the immediate vicinity of the metals. In addition to the catalytic domain, the plant enzyme contains a second domain of unknown function. A search of sequence databases was undertaken using a sequence pattern which includes the conserved metal-binding residues in the plant and animal enzymes. The search revealed the presence in plants of a 'mammalian-type' low molecular weight purple acid phosphatase, a high molecular weight form in some fungi, and a homologue in some bacteria. The catalytic mechanism of the enzyme has been investigated with a view to understanding the marked difference in specificity between the Fe-Mn sweet potato enzyme, which exhibits highly efficient catalysis towards both activated and unactivated phosphate esters, and other PAPs, which hydrolyse only activated esters. Comparison of the active site structures of the enzymes reveal some interesting differences between them which may account for the difference. The implications fur understanding the physiological functions of the enzymes will be discussed.

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